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Newswise - News for Journalists
Newswise Special Wire
Tuesday, August 8, 2017

Public edition |

Newswise Cancer Research Wire for 08-Aug-2017

Prostate Cancer Cells Become ‘Shapeshifters’ to Spread to Distant Organs

Johns Hopkins Kimmel Cancer Center scientists report they have discovered a biochemical process that gives prostate cancer cells the almost unnatural ability to change their shape, squeeze into other organs and take root in other parts of the body. T...

– Johns Hopkins Medicine

Nature Communications; P50CA058236, CA070196, P50CA88843, P30CA006973, R01CA183965, U01CA196390, U54CA210173-01

‘Origami Organs’ Can Potentially Regenerate Tissues

Northwestern Medicine scientists and engineers have invented a range of bioactive “tissue papers” made of materials derived from organs that can potentially be used to support natural hormone production in young cancer patients and aid wound heal...

– Northwestern University

P50 HD076188-02

Embargo expired on 07-Aug-2017 at 09:00 ET

How a Chemo Drug Can Help Cancer Spread From the Breast to the Lungs

The very same treatment that thwarts breast cancer has a dark side – it can fuel the spread of the disease to the lungs. Researchers at The Ohio State University found clues to why it happens, opening up the possibility of interfering with the medi...

– Ohio State University

Embargo expired on 07-Aug-2017 at 15:00 ET

New Tumor Database Deployed to Battle Childhood Cancer at UC Santa Cruz

The Treehouse Childhood Cancer Initiative researchers at UC Santa Cruz Genomics Institute and the St. Baldrick’s Foundation are making a 11,000+ tumor database available for use by all researchers in the pediatric cancer community and beyond in our...

– University of California, Santa Cruz

Embargo expired on 07-Aug-2017 at 12:00 ET

Ninety-Seven Percent of Insurance Denials in Pediatric Proton Patients Overturned on Appeal

nsurance companies end up covering proton therapy treatment for pediatric cancer patients in 97 percent of the cases they originally deny once those decisions are appealed. Researchers from the Perelman School of Medicine at the University of Pennsyl...

– Perelman School of Medicine at the University of Pennsylvania

Rare Leukemia Targeted by Modifying Patients’ Immune Cells

Young patients with a particular type of leukemia who have relapsed after going into remission may find new hope through a treatment that involves modifying a patient’s own T cells, an important part of the immune system, to destroy cancer cells.

– Yale Cancer Center

Aspirin: Wonder Drug for Cancer Prevention?

Many are finding that aspirin can slow or prevent one of mankind's deadliest diseases: cancer. While the mechanism is still debated, some experts say aspirin reduces the inflammation that drives cancer.

– Yale Cancer Center

Good Cellular Neighbors Combat Incipient Cancers

When Yale researchers took a closer look at skin cells, they discovered the unaffected neighbor cells are not helplessly awaiting invasion of cancer cells but acting like cellular police, actively correcting tissue flaws created by their aberrant nei...

– Yale Cancer Center

Engineering and Medicine Combine to Fight Brain Cancer

A collaboration between two laboratories – one in Engineering and the other in Medicine – has led to a promising drug delivery system that uses nanoparticles to fight a particularly aggressive and hard-to-treat brain cancer.

– Yale Cancer Center

Does Radiology Contrast Medium Matter? To Fragile Cancer Patients, Yes

Given the choice of contrast medium for a computed tomography (CT) scan, most patients wouldn’t know the difference between the two iodine-based options commonly used in cancer cases. But for some patients, particularly in the already fragile and p...

– Sbarro Health Research Organization (SHRO)

Journal of Cellular Physiology

Fat Rats Show Why Breast Cancer May Be More Aggressive in Patients with Obesity

In an animal model of obesity and breast cancer, tumor cells in obese animals but not lean animals had especially sensitive androgen receptors, allowing these cells to magnify growth signals from the hormone testosterone.

– University of Colorado Cancer Center

Yale Chemist's Upcoming Trial Could Open Doors For New Medical Treatments

A Yale chemistry professor is closing in on a medical breakthrough that could help cure a rare genetic disorder as well as pioneer a novel way of treating disease.

– Yale Cancer Center

Urologists Seeking Patients for Groundbreaking Prostate Cancer Study

A research study to remove cancerous cells in the prostate using Magnetic Resonance Imaging guided technology is entering its final phase at Beaumont.

– Beaumont Health

Drug Short-Circuits Cancer Signaling

Drug zeroes in on mutated nuclear receptors found in cancer, leaves normal proteins alone

– Sanford Burnham Prebys Medical Discovery Institute

Nature Communications, 17 July 2017

Discovery Points to Drugs That Would ‘Short-Circuit’ Deadly Leukemia

St. Jude Children’s Research Hospital scientists have found that cells of a deadly acute myeloid leukemia can be killed by blocking production of a molecular “battery.”

– St. Jude Children's Research Hospital

JCI Insight, August 2017; CA194057; CA21745

Embargo expired on 03-Aug-2017 at 07:00 ET

New Research Shows the Power of Radiomics to Improve Precision Medicine

Precision medicine has become the leading innovation of cancer treatment. Patients are routinely treated with drugs that are designed to target specific tumors and molecules. Despite the progress that has been made in targeted cancer therapies, the p...

– Moffitt Cancer Center

Aggressive Breast Cancers May Contribute to Racial Survival Disparities


– University of North Carolina Health Care System

JNCI, August-2017

Comprehensive Sequencing Program Shows Promise of Precision Medicine for Advanced Cancer

A new study shows just how complex metastatic cancer is and offers some clues to attacking it. The study represents one of the largest and most comprehensive efforts to examine the genetic and molecular landscape of advanced cancer.

– Michigan Medicine - University of Michigan

Nature; 1UM1HG006508; CA214170 ; CA186786

Embargo expired on 02-Aug-2017 at 13:00 ET

UCLA study offers roadmap to personalized therapies for sarcoma and other aggressive cancers

Sarcoma is a rare and deadly form of cancer occurring in the bones and connective tissue that affects individuals of all ages. Its aggressiveness, rarity and diversity continue to hinder efforts to identify effective therapies for people with this ma...

– University of California, Los Angeles (UCLA), Health Sciences

JCO Precision Oncology

Embargo expired on 02-Aug-2017 at 16:00 ET

Scientists Deliver Knock-Out Blow to Multiple Cancers

Targeting healthy cells that have been hijacked by cancer cells could help treat many different types of the disease, according to research by scientists at the University of Southampton.

– University of Southampton

Journal of the National Cancer Institute

Embargo expired on 02-Aug-2017 at 20:00 ET

New Research Identifies Molecules That Could Help to Prevent the Development of Brain Tumours

Researchers from the University of Portsmouth’s Brain Tumour Research Centre of Excellence have identified molecules which are responsible for metastatic lung cancer cells binding to blood vessels in the brain.

– University of Portsmouth

International Journal of Molecular Sciences 2017, 18(7), 1474;

In-Depth Analysis of Metastatic Cancer Could Enable More Precise Treatments

HHMI Investigator Arul Chinnaiyan is using comprehensive tumor sequencing to better capture the drivers of metastatic cancer and treat the disease more effectively.

– Howard Hughes Medical Institute (HHMI)


Ferreting Out Causes of Resistance to Cancer Drugs

Cancer cells are smart and find ways to best even the newest of treatments. Chemo, radiation, targeted therapy, and other treatments may kill nearly all cancer cells, but some cells are either not affected, or change to survive treatment. In time, th...

– Perelman School of Medicine at the University of Pennsylvania

Findings That Could Lead to the First Blood Test for Kidney Cancer Presented at the 69th AACC Annual Scientific Meeting

A new study has discovered that two microRNAs could be used to develop the first-ever blood test for kidney cancer as well as novel treatments for this condition. These findings were presented today at the 69th AACC Annual Scientific Meeting & Clinic...

– American Association for Clinical Chemistry (AACC)

69th AACC Annual Scientific Meeting, Aug-2017

Embargo expired on 01-Aug-2017 at 09:30 ET

Study: History of Gum Disease Increases Cancer Risk in Older Women

Postmenopausal women who have a history of gum disease also have a higher risk of cancer, according to a new study of more than 65,000 women.

– University at Buffalo

Cancer Epidemiology, Biomarkers & Prevention, Aug-2017

Embargo expired on 01-Aug-2017 at 00:05 ET

Aye Group Discovers Avenue for Precision Cancer Treatment

One of the goals of personalized medicine is to be able to determine which treatment would work best by sequencing a patient’s genome. New research from the lab of Yimon Aye, assistant professor of chemistry and chemical biology, could help make th...

– Cornell University

How Powerful is CRISPR?

"Good morning, doctor, I am here for my gene editing appointment.” In the future, could this be a greeting heard in physician offices around the world? With the introduction of CRISPR technology, genetic material can now be more easily and precisel...

– 69th AACC Annual Scientific Meeting Press Program

69th AACC Annual Scientific Meeting

Forum of International Respiratory Societies Continues Grassroots World Lung Cancer Efforts

On World Lung Cancer Day, August 1, the American Thoracic Society and fellow members of the Forum of International Respiratory Societies (FIRS) commemorates, celebrates and supports those impacted by lung cancer. FIRS continues to support the grassro...

– American Thoracic Society (ATS)

Livestreaming Today: Star Trek Tricorder XPrize Winning Device Presentation

Press can register here to livestream this special session through Newswise Live on Monday, July 31 at 7:30 PM EDT

– Newswise

Refuting the Idea That Mutations Cause Cancer

Writing today in the journal Cancer Research, James DeGregori, PhD, deputy director of the University of Colorado Cancer Center offers evidence that it is forces of evolution driven by natural selection acting in the ecosystem of the body that, in th...

– University of Colorado Cancer Center

How DNA Damage Turns Immune Cells Against Cancer

The delayed arrival of immune cells after cancer therapy is well documented and critical for responses to chemotherapy and radiation, yet the events underlying their induction remain poorly understood. Now, Penn researchers have discovered how DNA da...

– Perelman School of Medicine at the University of Pennsylvania

CA17494, CA138835, GM101149

Argonne Goes Deep to Crack Cancer Code

Argonne researchers tackling cancer through deep learning with an eye towards the future and exascale computing.

– Argonne National Laboratory

Fred Hutch Tip Sheet: Glioblastoma, Tumor Microenvironment and More

Quick summaries for journalists that offer sources and story ideas from Fred Hutch. Each links to more detailed information and includes contact information for arranging interviews. Topics include Glioblastoma, tumor microenvironment and more.

– Fred Hutchinson Cancer Research Center

Cancer-Death Button Gets Jammed by Gut Bacterium

Researchers at Michigan Medicine and in China showed that a type of bacterium is associated with the recurrence of colorectal cancer and poor outcomes. They found that Fusobacterium nucleatum in the gut can stop chemotherapy from causing a type of ca...

– Michigan Medicine - University of Michigan

Cell; CA211016

Embargo expired on 27-Jul-2017 at 12:00 ET

WashU Biomedical Engineer Combines Data, Algorithms to Understand HER2 Breast Cancer Gene

In American women, breast cancer is the second most common cancer and the second leading cause of cancer death. Using data, algorithms and lab experimentation, a biomedical engineer at Washington University in St. Louis is studying breast cancer at t...

– Washington University in St. Louis

Integrative Biology

Glowing Tumor Technology Helps Surgeons Remove Hidden Cancer Cells

Surgeons were able to identify and remove a greater number of cancerous nodules from lung cancer patients when combining intraoperative molecular imaging (IMI) – through the use of a contrast agent that makes tumor cells glow during surgery – wi...

– Perelman School of Medicine at the University of Pennsylvania

1F32CA210409; R01 CA193556

Researchers Show Curcumin Protects Against Chemoresistant Pancreatic Cancer

Researchers at Baylor Scott & White Research Institute reveal curcumin has potential to overcome chemoresistance in pancreatic ductal adenocarcinoma, a common but aggressive form of cancer in the pancreas.

– Baylor Scott and White Health

Carcinogenesis, July-2017

Study Finds Breast Cancer Driver, HER2, in 3 Percent of Lung Cancers

The Lung Cancer Mutation Consortium at the University of Colorado Cancer Center reports this week in the journal Cancer that 24 of 920 patients (3 percent) with advanced-stage lung cancer had mutations in the gene HER2. Seventy-one percent of these p...

– University of Colorado Cancer Center

Seattle Children's Opens CD22 CAR T-Cell Immunotherapy Trial for Children and Young Adults Whose Leukemia Escapes CD19 CAR T-Cell Therapy

After seeing promising results in phase 1 of the Pediatric Leukemia Adoptive Therapy (PLAT-02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, researchers at Seatt...

– Seattle Children's Hospital

Stem Cell Therapy Attacks Cancer by Targeting Unique Tissue Stiffness

A stem cell-based method created by University of California, Irvine scientists can selectively target and kill cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way.

– University of California, Irvine

Science Translational Medicine, July 26, 2017

Randomized Clinical Trials Shown to Accurately Predict Real-World Overall Survival

Value in Health, the official journal of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), announced today the publication of new research examining the relationship between the efficacy of randomized controlled trials an...

– International Society for Pharmacoeconomics and Outcomes Research (ISPOR)

Value in Health, Jul-Aug-2017

Future Doctors Spend ‘A Day in the Life’ of a Skin Cancer Patient

All too frequently doctors are faced with the challenge of breaking bad news to patients. A new research study by Queen’s University Belfast suggests that techniques allowing medical students to ‘walk in the shoes’ of a patient may better prepa...

– Queen's University Belfast

No Longer Lost in Translation

Mouse models have advanced our understanding of immune function and disease in many ways but they have failed to account for the natural diversity in human immune responses. As a result, insights gained in the lab may be lost in translation. In their...

– La Jolla Institute for Allergy and Immunology

Nature Communications (2017) ; National Institutes of Health; Deutsche Forschungsgemeinschaft

In Assessing Risk of Hormone Therapy for Menopause, Dose — Not Form — Matters

UCLA-led research finds that the way estrogen therapy for menopause is delivered doesn’t affect risk or benefit. What DOES make a difference with the commonly used conjugated equine estrogen, plus progestogen, is dosage.

– University of California, Los Angeles (UCLA), Health Sciences


Touching Lives Through Telehealth for Ostomy Patients

One UAB School of Nursing faculty member is impacting outcomes for ostomy patients with online postoperative visits.

– University of Alabama at Birmingham

Virginia Tech Carilion Research Institute Teams Converge on Strategies to Defeat McCain’s Form of Brain Cancer

Research teams at the Virginia Tech Carilion Research Institute from three colleges — Engineering, Science, and Veterinary Medicine — are developing new approaches to treat glioblastoma, the aggressive form of brain cancer diagnosed in U.S. Sen. ...

– Virginia Tech

Scientists Identify Gene Mutations in Smoking-Related Cancers

African-Americans typically have worse outcomes from smoking-related cancers than Caucasians, but the reasons for this remain elusive. However, scientists at Wake Forest Baptist Medical Center have taken a big step toward solving this puzzle.

– Wake Forest Baptist Medical Center

Theranostics, July-2017

CU Cancer Center Study May Explain Failure of Retinoic Acid Trials Against Breast Cancer

University of Colorado Cancer Center study published online ahead of print in the journal Oncogene offers compelling evidence explaining failure of retinoic acid trials against breast cancer and offers a possible strategy for their use.

– University of Colorado Cancer Center



Mayo Clinic ranked top hospital nationwide by U.S. News & World Report

Mayo Clinic was again named the best hospital in the country in U.S. News & World Report’s annual list of top hospitals published on the U.S. News & World Report website today.

– Mayo Clinic

Embargo expired on 08-Aug-2017 at 00:05 ET

Roswell Park Cancer Institute Named a U.S. News ‘Best Hospital’ For Cancer

Roswell Park Cancer Institute has been named a 2017–18 Best Hospital for cancer by U.S. News & World Report. The Buffalo, N.Y., comprehensive cancer center was ranked by the news outlet as 33rd among nearly 900 cancer hospitals reviewed nationwide,...

– Roswell Park Cancer Institute

Embargo expired on 08-Aug-2017 at 00:05 ET

Dana-Farber/Brigham and Women's Cancer Center the Best in the Region for Cancer Care for 17th Year

Dana-Farber /Brigham and Women's Cancer Center is ranked no. 4 in cancer by U.S. News and World Report.

– Dana-Farber Cancer Institute

The University of Kansas Cancer Center Receives Renewal of National Cancer Institute Designation and Announces Approval of Children’s Mercy as an Official Consortium Partner

The University of Kansas Cancer Center announced today that the National Cancer Institute (NCI) renewed its national cancer center designation for five years and that Children’s Mercy has been formally approved as a cancer center consortium partner...

– University of Kansas Cancer Center

NCCN Foundation Announces Fifth 2017 Young Investigator Award

NCCN Foundation Young Investigator Awards provide funding over a two-year period for research initiatives focused on assessing and improving outcomes in cancer care.

– National Comprehensive Cancer Network® (NCCN®)

Dana-Farber Debuts New Name, State-of-the-Art Facility for Integrative Therapies

The Dana-Farber Cancer Institute is pleased to announce the opening of the new Leonard P. Zakim Center for Integrative Therapies and Healthy Living, underscoring Dana-Farber’s commitment to providing cutting-edge patient therapies and support for t...

– Dana-Farber Cancer Institute

NCCN “Just Bag It!” Campaign Reaches 100 Adopters Nationwide

100 cancer centers throughout the country have pledged to adopt a life-saving administration policy for vincristine

– National Comprehensive Cancer Network® (NCCN®)

FDA Awards Orphan Status to Brain Cancer Vaccine Developed at Roswell Park Cancer Institute

The U.S. Food and Drug Administration has awarded orphan drug status to SurVaxM, a promising immunotherapy vaccine developed at Roswell Park Cancer Institute and being studied as a treatment for glioblastoma, a type of brain cancer.

– Roswell Park Cancer Institute

Cancer Research Institute and Israel Cancer Research Fund Announce Launch of the Immunotherapy Promise Initiative

A collaborative campaign brings together the leading funder of immunotherapy research internationally with North America’s largest nonprofit dedicated to supporting Israeli cancer research

– Cancer Research Institute

Better Outcomes for Young Women Surviving Cancer

Reproductive health is not the same as sex ed,” Teresa K. Woodruff, PhD, from the Feinberg School of Medicine, Northwestern University, reminded us in yesterday’s plenary session, “Oncofertility: From Bench to Bedside to Babies.” The war on c...

– 69th AACC Annual Scientific Meeting Press Program

69th AACC Annual Scientific Meeting Press Program

Twenty-Three ASTRO Members Awarded Fellows Designation

The American Society for Radiation Oncology has selected 23 distinguished members to receive the ASTRO Fellow designation. The 2017 class of Fellows will be recognized during the Awards Ceremony at ASTRO’s 59th Annual Meeting, to be held September ...

– American Society for Radiation Oncology (ASTRO)

Theodoros N. Teknos, MD, Named President and Scientific Officer of University Hospitals Seidman Cancer Center

Announcement of new president for University Hospitals Seidman Cancer Center in Cleveland: Theodoros N. Teknos, MD.

– University Hospitals Cleveland Medical Center

Spirit of EAGLES Event Focused on Cancer in Native Communities Coming to Niagara Falls, NY in September

Roswell Park Cancer Institute and the Mayo Clinic Cancer Center are jointly hosting the 10th annual Spirit of EAGLES: Changing Patterns of Cancer in Native Communities conference, to be held Sept. 21–24 in Niagara Falls, New York.

– Roswell Park Cancer Institute

Case Western Reserve University School of Medicine Faculty Receives Funding for Pediatric Cancer Research

Alex Huang has been awarded a $150,000 St. Baldrick’s Foundation Innovation Award.

– Case Western Reserve University

$450K in Fellowship Grants Awarded to Rutgers Cancer Institute Investigators

Rutgers Cancer Institute of New Jersey investigators have received $450,000 in funding to support research projects in immunotherapy and basic science research that could impact pancreatic, breast and other cancers. The Pre- and Post-Doctoral Fellows...

– Rutgers Cancer Institute of New Jersey

Penn Center for Precision Medicine Awards $565,000 in Second Accelerator Grants

The Penn Center for Precision Medicine (PCPM) Accelerator Fund awarded eight research teams from Penn Medicine in their second round of funding for the implementation of personalized medicine projects across a range of clinical specialties.

– Perelman School of Medicine at the University of Pennsylvania

Chemoradiation Researcher, Retired Brigadier General Receives 2017 ASTRO Honorary Membership

Edith Peterson Mitchell, MD, a leading researcher, medical oncologist and proponent of combined modality treatment, has been chosen as the 2017 American Society for Radiation Oncology (ASTRO) Honorary Member.

– American Society for Radiation Oncology (ASTRO)

Childhood Cancer Research at UAB Continues with Grants From St. Baldrick’s Foundation

Pediatric neurosurgeons, oncologists and molecular imaging physicians continue to work toward better diagnoses, treatments and cures for childhood cancer.

– University of Alabama at Birmingham

Bio-Rad Announces the Addition of Analytes for Liquichek Tumor Marker Control

Bio-Rad Laboratories, Inc. a global provider of life science research and clinical diagnostic products, today announced the addition of four new analytes to the company’s Liquichek Tumor Marker Control.

– 69th AACC Annual Scientific Meeting Press Program

All Meeting News on Newswise

Higher Education Events

Tenth Annual HERO Event Celebrates Those on Cancer Clinical Trials

The Helping to Enhance Research in Oncology program will hold its tenth annual celebration event. The event honors those on cancer clinical trials and raises awareness for the importance of cancer clinical trials. The event will offer public informat...

– University of New Mexico Comprehensive Cancer Center

Expert Pitch

Virginia Tech Carilion Research Institute Teams Converge on Strategies to Defeat McCain’s Form of Brain Cancer

– Virginia Tech





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