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Newswise Special Wire
Tuesday, August 15, 2017

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Newswise Cancer Research Wire for 15-Aug-2017
 

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.



Skewing the Aim of Targeted Cancer Therapies

The aim of targeted gene-based cancer therapies could often be skewed from the start. A widespread concept about how cells produce proteins proved incorrect 62% of the time in a new study in ovarian cancer cells of the relationship between RNA and pr...

– Georgia Institute of Technology

Scientific Reports; Ovarian Cancer Institute; The Deborah Nash Endowment Fund; Northside Hospital; CHE-452 1454501

Embargo expired on 15-Aug-2017 at 05:00 ET


Blood Biopsy Reveals Unique, Targetable Genetic Alterations in Patients with Rare Cancer

Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a ...

– University of California San Diego Health

Cancer Research

Embargo expired on 15-Aug-2017 at 12:00 ET


How Decision-Making Habits Influence the Breast Cancer Treatments Women Consider

A new study finds that more than half of women with early stage breast cancer considered an aggressive type of surgery to remove both breasts. The way women generally approach big decisions, combined with their values, impacts what breast cancer trea...

– Michigan Medicine - University of Michigan

Cancer; CA163233

Embargo expired on 15-Aug-2017 at 10:00 ET


WashU Study: Birth Defects, Cancer Linked

Some children born with birth defects may be at increased risk for specific types of cancer, according to a new review from the Brown School and the School of Medicine at Washington University in St. Louis.

– Washington University in St. Louis


Cancer-Fighting T Cells Are Smarter, Stronger Than Experts Thought

It takes a minuscule amount of force to make T cells behave in the lab as they behave in the body. That finding is a leap in cancer therapy research.

– Vanderbilt University

Proceedings of the National Academy of Sciences, Aug-2017; R01AI100643; SU2C-AACR-DT1314

Embargo expired on 14-Aug-2017 at 15:00 ET


Proteins Developed at Boise State University Effectively Fight 58 Types of Tumors

Boise State University researchers have created anti-cancer drugs that are effective at killing 58 of the 60 types of tumors found in the National Cancer Institutes NCI-60 panel of cancer cells, which affect nine organ systems in the human body.

– Boise State University

Embargo expired on 14-Aug-2017 at 10:00 ET


Breast Cancer Study in India Shows How the Country Can Avoid Crisis

The research, which is the first of its kind to look at breast cancer awareness in India, found that cultural and religious issues mean that women don’t access health services, are reluctant to consult male doctors, neglect their own health due to ...

– University of Portsmouth


Too Many Drug Trials, Too Few Patients

With the arrival of two revolutionary treatment strategies, immunotherapy and personalized medicine, cancer researchers have found new hope — and a problem that is perhaps unprecedented in medical research.

– Yale Cancer Center


Study Pinpoints Gene’s New Role in Pancreatic Cancer

Pancreatic cancer is a particularly deadly form of disease, and patients have few options for effective treatment. But a new Yale Cancer Center study has identified a gene that is critical to pancreatic cancer cell growth, revealing a fresh target fo...

– Yale Cancer Center


Does Stronger Initial Response to Cancer Treatment Predict Longer Overall Survival?

It seems like such a simple question: Do patients whose tumors shrink more in response to targeted treatment go on to have better outcomes than patients whose tumors shrink less? But the implications of a recent study demonstrating this relationship ...

– University of Colorado Cancer Center


Findings Pave Way for Three-Drug Combination Treatment for Childhood Leukemia

UCLA researchers have developed a new approach that could eventually help young people respond better to treatment for acute lymphoblastic leukemia. The scientists discovered in mice that when the production of nucleotides -- also known as the buildi...

– University of California, Los Angeles (UCLA), Health Sciences


Clinical Trial Eligibility Criteria a Growing Obstacle

Despite a decade-long call for simplification of clinical trials, the number of criteria excluding patients from participating in clinical trials for lung cancer research continues to rise.

– UT Southwestern Medical Center

Journal of Thoracic Oncology-2017


SLU Surgeons Study “Awake Aneurysm Surgery” for Better Outcomes

Saint Louis University researchers are encouraged by study results which they hope can reduce the risks associated with this type of brain surgery.

– Saint Louis University Medical Center

Journal of Neurosurgery


Discovery of New Prostate Cancer Biomarkers Could Improve Precision Therapy

ROCHESTER, Minn. — Mayo Clinic researchers have identified a new cause of treatment resistance in prostate cancer. Their discovery also suggests ways to improve prostate cancer therapy. The findings appear in Nature Medicine.

– Mayo Clinic


Cardiovascular Aging Symposium Explores Relationship Between Dysfunction and Disease Development

During the “Novel Implications for Blood Flow and Vascular Dysfunction in Non-cardiovascular Related Disease” symposium at the APS Cardiovascular Aging: New Frontiers and Old Friends conference, researchers will present findings that emphasize th...

– American Physiological Society (APS)

Embargo expired on 12-Aug-2017 at 20:00 ET


Using Alternative Medicine Only for Cancer Linked to Lower Survival Rate

Patients who choose to receive alternative therapy as treatment for curable cancers instead of conventional cancer treatment have a higher risk of death, according to researchers from the Cancer Outcomes, Public Policy and Effectiveness Research (COP...

– Yale Cancer Center


Sweet! Sugar-Coated Probe Yields Better Acid Test

When our cells’ acid-alkaline balance goes wrong, it can go wrong in a big way—think cancer and cystic fibrosis. New fluorescent probes make it easier to detect pH and sweetened the deal by adding sugar to his acid-sensitive probes, making them m...

– Michigan Technological University

ACS Sensors, June 2017 ; National Institute of General Medical Sciences of the National Institutes of Health, Award Number R15GM114751


Know Your Risk for Ovarian CancerMount Sinai Experts Share Tips for Ovarian Cancer Awareness Month in September

Ovarian cancer is the fourth leading cause of death in American women and according to the National Cancer Institute, approximately 22,000 women will be diagnosed with the disease and 14,000 will die from it.

– Mount Sinai Health System


Out-of-Pocket Costs Exceed What Many Insured Cancer Patients Expect to Pay

A third of insured people with cancer end up paying more out-of-pocket than they expected, despite having health coverage, researchers at the Duke Cancer Institute have found.

– Duke Health

JAMA Oncology

Embargo expired on 10-Aug-2017 at 11:00 ET


Checkpoint Inhibitors Fire Up Different Types of T Cells to Attack Tumors

Cancer immunotherapies that block two different checkpoints on T cells launch immune attacks on cancer by expanding distinct types of T cell that infiltrate tumors, researchers from The University of Texas MD Anderson Cancer Center report in the jour...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 10-Aug-2017 at 12:00 ET


A Metabolic Pathway That Feeds Liver Cancer

A little-studied gene may explain how some liver cancer cells obtain the nutrition they need to proliferate, according to new research from the University of Maryland.

– American Society for Biochemistry and Molecular Biology (ASBMB)

Journal of Biological Chemistry, Aug 18 2017


Fred Hutch Aims to Eliminate Cancers Caused by Infections

Fred Hutchinson Cancer Research Center is launching a new integrated research center to prevent and find cures for cancers caused by infectious agents. It will be led by Dr. Denise Galloway, a Fred Hutch microbiologist whose research paved the way fo...

– Fred Hutchinson Cancer Research Center


Protecting Kids Against HPV Before Cancer Risk Increases

It is that time of year for kids returning to school to get vaccinated before the school year starts. But the controversy over the HPV vaccine continues to rage as it has since its introduction in the U.S. in 2014.

Expert Available

– University of California, Los Angeles (UCLA), Health Sciences


Black Men Have Lowest Survival Rates Among Patients with Anal Cancer

As published in JNCCN – Journal of the National Comprehensive Cancer Network, researchers at UT Southwestern Medical Center found significant racial and gender-based disparities in outcomes among patients with locoregional anal cancer.

– National Comprehensive Cancer Network® (NCCN®)


Moffitt Cancer Center & Cvergenx Partner to Personalize Radiation Therapy

Moffitt’s Radiation Oncology Department will utilize Cvergenx’s Genomic-Adjusted Radiation Dose (GARD) model.

– Moffitt Cancer Center


Researchers Look to Improve Detection of Skin Cancer Lacking Pigment Melanin

UNC Lineberger scientists led a multi-institution research team to identify key features linked to amelanotic melanoma, a form of skin cancer that lacks the brown or black color that stems from the pigment melanin.

– University of North Carolina Health Care System

JAMA Dermatology, Aug-2017


Identifying a New Type of Liver Tumor

Investigators at Children's Hospital Los Angeles have succeeded in better defining a rare pediatric malignant liver disease — a necessary step in achieving an optimum treatment.

– Childrens Hospital Los Angeles

Histopathology, June 2017


First-in-Class Drug Holds Promise for Therapy-Resistant Breast Cancer

First-in-class drug holds promise for therapy-resistant breast cancer

– UT Southwestern Medical Center

eLife, Aug-2017


Seattle Cancer Care Alliance Again Ranked Top Five in the U.S. For Adult Cancer Care

For more than a decade, SCCA/UWMC consistently has maintained a top standing among the top hospitals for adult cancer care in the U.S.

– Seattle Cancer Care Alliance


New Genes Discovered Regulating Brain Metastases in Lung Cancer Patients

The researchers set out to find which genes can regulate the cells that initiate brain metastases - what are the genes that are sending the signal to leave the lung tumour, go into the blood stream, invade the blood-brain barrier and form a tumour i...

– McMaster University


NYITCOM Researcher Discovers Potential Cancer Treatment Breakthrough

Patients undergoing conventional chemotherapy for certain cancers could potentially receive more effective and less toxic drug treatment.

– New York Institute of Technology

Proceedings of National Academy of Sciences


New Study Discovers "Killer Peptide" That Helps Eliminate Resistant Cancer Cells

A new study by University of Kentucky Markey Cancer Center researchers shows that when therapy-sensitive cancer cells die, they release a "killer peptide" that can eliminate therapy-resistant cells.

– University of Kentucky

Cancer Research


Announcements


Children's Hospital of Philadelphia to Lead New Pediatric Data Resource Center for Research in Childhood Cancer and Structural Birth Defects

The Center for Data Driven Discovery in Biomedicine at Children’s Hospital of Philadelphia (CHOP) will lead a new, collaborative effort funded by the National Institutes of Health Common Fund to discover the causes of pediatric cancer and structura...

– Children's Hospital of Philadelphia


Stem Cell Transplant Program Celebrates First Year

The University of New Mexico Comprehensive Cancer Center began helping New Mexicans with blood disorders a little more than one year ago. It is the state’s only bone marrow transplant program. The program offers treatment choices for people with ly...

– University of New Mexico Comprehensive Cancer Center


American Society for Radiation Oncology Hires New Assistant Director of Congressional Relations

The American Society for Radiation Oncology (ASTRO) recently welcomed Margarita Valdez as its assistant director of congressional relations, a key position on its government relations and advocacy team.

– American Society for Radiation Oncology (ASTRO)


New NCCN Patient Resources for Rectal Cancer Now Available

Together with the NCCN Guidelines for Patients®: Colon Cancer, these free resources aid in decision-making for patients with colon and rectal cancers.

– National Comprehensive Cancer Network® (NCCN®)


American Thyroid Association Awards Research Grant to Marco Medici, MD, PhD, MSc, Erasmus Medical Center

The American Thyroid Association has awarded a 2017 Research Grant to Marco Medici, MD, PhD, MSc, a clinical fellow in endocrinology at Erasmus Medical Center in Rotterdam, The Netherlands. In his project, “Personalized Management of Thyroid Diseas...

– American Thyroid Association


American Thyroid Association Awards ThyCa Research Grant to Glenn J. Hanna, M.D., Dana-Farber Cancer Institute’s Center for Head and Neck Oncology

The American Thyroid Association has awarded a 2017 Research Grant, funded by the Thyroid Cancer Survivors’ Association, Inc. (ThyCa), to Glenn J. Hanna, MD. Dr. Hanna is a Staff Physician at the Dana-Farber Cancer Institute (DFCI)’s Center for H...

– American Thyroid Association


American Thyroid Association Awards ThyCa Research Grant to Jens Lohr, MD, PhD, Dana Farber Cancer Institute

The American Thyroid Association has awarded a 2017 Research Grant, funded by the Thyroid Cancer Survivors’ Association, Inc. (ThyCa), to Jens Lohr, MD, PhD, who is Assistant Professor of Medicine in the Medical Oncology Department at Dana-Farber C...

– American Thyroid Association


American Thyroid Association Awards ThyCa Research Grant to Vicki Emma Smith, PhD, University of Birmingham, UK

The American Thyroid Association has awarded a 2017 Research Grant, funded by the Thyroid Cancer Survivors’ Association, Inc. (ThyCa), to Vicki Emma Smith, PhD, Lecturer in Molecular Endocrinology at the University of Birmingham, UK. Dr. Smith’s ...

– American Thyroid Association


American Thyroid Association Awards Research Grant to Jason E. Coleman, PhD, University of Florida

The American Thyroid Association has awarded a 2017 Research Grant to Jason E. Coleman, PhD, Assistant Professor of Pediatrics at the University of Florida in Gainesville. Dr. Coleman’s project, “Effects of Early Hypo- and Hyperthyroidism on Long...

– American Thyroid Association


American Thyroid Association Awards Bite Me Cancer Research Grant to Brian P. Danysh, PhD, University of Texas MD Anderson Cancer Center

The American Thyroid Association has awarded a 2017 Research Grant, funded by Bite Me Cancer, to Brian P. Danysh, PhD, Instructor in Endocrine Neoplasia and Hormonal Disorders at the University of Texas MD Anderson Cancer Center. Dr. Danysh’s proje...

– American Thyroid Association


American Thyroid Association Awards Research Grant to Lawrence A. Shirley, MD, MS, FACS, Ohio State University Wexner Medical Center

The American Thyroid Association has awarded a 2017 Research Grant to Lawrence A. Shirley, MD, MS, FACS, Assistant Professor of Surgical Oncology, Ohio State University Wexner Medical Center. Dr. Shirley’s project is entitled “Impact of BRAF-Muta...

– American Thyroid Association


ASTRO Journal Advances in Radiation Oncology Now Indexed in PubMed Central

Advances in Radiation Oncology, the newest journal of the American Society for Radiation Oncology (ASTRO), is now indexed by PubMed Central, a free, full-text archive of biomedical and life sciences literature organized by the U.S. National Institute...

– American Society for Radiation Oncology (ASTRO)

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