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Newswise Special Wire
Tuesday, August 29, 2017

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Newswise Cancer Research Wire for 29-Aug-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Study: Most Melanomas Don’t Arise From Existing Moles

A study has found that less than one-third of melanomas arise from existing moles, while the vast majority appear on the skin as new spots. Additional research indicates that less than half of consumers look for broad-spectrum protection when choosin...

– American Academy of Dermatology

Journal of the American Academy of Dermatology

Embargo expired on 29-Aug-2017 at 03:05 ET

The Understudied Consequences of Peripheral Neuropathy after Chemotherapy

In two papers published in the Journal of the National Cancer Institute researchers from UC Davis, UCLA and other institutions have found that peripheral neuropathy, which causes pain, numbness, and tingling in hands and/or feet, can bother early-sta...

– UC Davis Comprehensive Cancer Center


Boosting Immune Cell Memory to Improve Vaccines and Cancer Immunotherapy

In mouse experiments, researchers at University of California San Diego School of Medicine have discovered that drugs that activate the cells’ proteasome, or recycling center, tip the balance in favor of memory CD8+ T cells. This approach could be ...

– University of California San Diego Health

Journal of Clinical Investigation

Embargo expired on 28-Aug-2017 at 16:00 ET

New App Uses Smartphone Selfies to Screen for Pancreatic Cancer

A new app from University of Washington researchers could lead to earlier detection of pancreatic cancer -- simply by snapping a smartphone selfie. The disease kills 90 percent of patients within five years, in part because no telltale symptoms or no...

– University of Washington

UbiComp 2017

Muscle Disease Patients Gather to Learn About Myositis

The Myositis Association (TMA) hosts their 2017 Annual Patient Conference September 7-10 at the Sheraton San Diego Hotel and Marina. With more than 80 presentations and nearly 500 myositis patients, friends, and family members in attendance, this con...

– Myositis Association

Stroke Prevention, HPV Vaccines, Early Drinking, Immunotherapy, and More in the Public Health News Source

The latest research, experts and features in Public Health in the Public Health News Source

– Newswise

Adding Radiation Treatments to Inoperable Lung Cancer Increases Survival by up to One Year

Patients with unresectable, or inoperable, lung cancer are often given a dismal prognosis, with low rates of survival beyond a few years. Researchers exploring combination therapies have recently discovered improved survival rates by up to one year ...

– Sbarro Health Research Organization (SHRO)


Cancer Treatments Can Change the Sense of Taste, Nutrition Expert Warns

Cancer treatments have many effects on patients – some apparent and some less so. One of the most noticeable changes is a change in taste.

Expert Available

– University of California, Los Angeles (UCLA), Health Sciences

Cancer Drug May Benefit Patients with Inherited Form of Kidney Disease

• A tyrosine kinase inhibitor approved for the treatment of certain cases of chronic myeloid leukemia slowed cyst growth in patients with autosomal dominant polycystic kidney disease.

– American Society of Nephrology (ASN)

doi: 10.2215/CJN.01530217

Embargo expired on 24-Aug-2017 at 17:00 ET

HPV Vaccine Significantly Lowers Rate of Second Cancer for Childhood Cancer Survivors

Health care provider recommendation of HPV vaccines could help decrease secondary cancers in childhood cancer survivors.

– University of Alabama at Birmingham

Journal of Clinical Oncology, Aug-2017

Embargo expired on 24-Aug-2017 at 16:00 ET

HPV Vaccination Rates Lag for Vulnerable Population of Childhood Cancer Survivors

Research suggests health providers are key to boosting HPV vaccination rates of childhood cancer survivors, who, as a group, are at increased risk for second cancers associated with the human papillomavirus.

– St. Jude Children's Research Hospital

Journal of Clinical Oncology, August 24

Embargo expired on 24-Aug-2017 at 16:00 ET

Scientists Develop Novel “Dot” System to Improve Cancer Detection

SBP researchers advance tumor-imaging nanosystem for enhanced diagnostic imaging

– Sanford Burnham Prebys Medical Discovery Institute

Nature Communications

This Is How Belly Fat Could Increase Your Cancer Risk

A new Michigan State University study now offers new details showing that a certain protein released from fat in the body can cause a non-cancerous cell to turn into a cancerous one. The federally funded research also found that a lower layer of abdo...

– Michigan State University


DNA Sensor Plays Critical Role in Cancer Immunotherapy via Robust Response to Unexpected Form of DNA

UT Southwestern Medical Center researchers report for the first time that tumors stressed by cancer immunotherapy release their mitochondrial DNA into nearby immune cells, triggering a host alert system.

– UT Southwestern Medical Center


Still Laboratory Seeks ‘Novel Lead Compound’ to Help Treat Cancer

Still uses the NMR spectrometer to conduct his research on plant extracts he procured from the National Cancer Institute (NCI) Active Repository Program.

– California State University, Dominguez Hills

State’s Stem Cell Agency Awards $18.2 Million Grant for B Cell Cancer Clinical Trial

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) today unanimously approved an $18.29 million grant to University of California San Diego School of Medicine researchers to fund a phase Ib/IIa c...

– University of California San Diego Health

Fred Hutch Tip Sheet: Breast Cancer, Skin Cells as a Cancer Repair Mechanism, HIV Prevention Study, Air Pollution Risk and More

The August tip sheet from Fred Hutch includes stories on breast cancer, skin cells as a cancer repair mechanism, an HIV prevention study, air pollution risk and more -- Here are quick summaries for journalists that offer sources and story ideas from ...

– Fred Hutchinson Cancer Research Center

CRI Scientists Develop an Innovative System to Characterize Regulatory DNA Sequences Responsible for Human Diseases

Scientists from the Children’s Medical Center Research Institute at UT Southwestern (CRI) have developed an innovative system to identify and characterize the molecular components that control the activities of regulatory DNA sequences in the human...

– UT Southwestern Medical Center

Cell, Aug-2017

On the Other Hand, the Immune System Can Also CAUSE Cancer

University of Colorado Cancer Center paper describes how immune response designed to scramble HPV DNA can scramble human DNA as well, sometimes in ways that cause cancer.

– University of Colorado Cancer Center


Putting It to the Test

University of Utah researchers led by chemical engineering and chemistry professor Marc has developed a rapid portable screening test for liver cancer that doesn’t involve sending a specimen to a blood lab and cuts the wait time for results from tw...

– University of Utah

New Method of Isolating Tumor Cells Could Improve Cancer Research and Treatment

Researchers from the University of Georgia and the Georgia Cancer Center at Augusta University have created a microfluidic device to isolate tumor cells quickly and efficiently

– University of Georgia

The Medical Minute: An Especially Challenging Brain Cancer Diagnosis

Most brain cancers start elsewhere in the body, but one particularly aggressive and uncommon form – glioblastoma – originates in the brain itself.

– Penn State Health Milton S. Hershey Medical Center

Retention of One Normal Version of BRCA Gene in Breast and Ovarian Cancers Influences Patient Survival, According to Penn-Led Study

Researchers found a relationship between the genetics of tumors with germline BRCA1/2 mutations and whether the tumor retains the normal copy of the BRCA1/2 gene, and risk for primary resistance to a common chemotherapy that works by destroying cance...

– Perelman School of Medicine at the University of Pennsylvania

W81XWH-13-1-0338, 5T32GM008638-15

Embargo expired on 22-Aug-2017 at 05:00 ET

New Recommendations for Managing Menopausal Symptoms in Breast Cancer Survivors

A large proportion of the world’s estimated 9.3 million breast cancer survivors experience menopausal symptoms or clinical manifestations of estrogen deficiency. A comprehensive review published in the Endocrine Society’s Journal of Clinical Endo...

– Endocrine Society

Journal of Clinical Endocrinology & Metabolism, Aug-2017

Spaser Can Detect, Kill Circulating Tumor Cells to Prevent Cancer Metastases, Study Finds

A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells in the blood stream and then killing these cells, according to a new research study.

– Georgia State University

Nature Communications

CRI Scientists Discover Vitamin C Regulates Stem Cell Function and Suppresses Leukemia Development

Not much is known about stem cell metabolism, but a new study from the Children’s Medical Center Research Institute at UT Southwestern (CRI) has found that stem cells take up unusually high levels of vitamin C, which then regulates their function a...

– UT Southwestern Medical Center


An Opening for Early Detection: What Your Mouth Says About Your Health

Dentists and hygienists see more than just teeth. They can see early signs of certain diseases — often before patients know they have them.

– University of Alabama at Birmingham

GIST Tumors Linked to NF1 Mutations, Genetic Testing Needed

Researchers at UC San Diego Moores Cancer Center, with colleagues from Memorial Sloan Kettering Cancer Center and Fox Chase Cancer Center, have determined that a specific region of the small bowel, called the duodenal-jejunal flexure or DJF, shows a ...

– University of California San Diego Health

JCO Precision Oncology

Make Way for Hemoglobin

Harvard Medical School researchers have identified the mechanism behind red blood cell specialization. Their findings could spark the development of new treatments for blood disorders and cancers.

– Harvard Medical School

Science, Aug-2017

Few Women with History of Breast Cancer and Ovarian Cancer Take a Recommended Genetic Test

More than 80 percent of women living with a history of breast or ovarian cancer at high-risk of having a gene mutation have never taken the test that can detect it.

– University of California, Los Angeles (UCLA), Health Sciences

Journal of Clinical Oncology

Wistar Scientists Develop Novel Immunotherapy Technology for Prostate Cancer

A study led by Wistar scientists describes a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA to directly encode protective antibodies against a cancer specific protein.

– Wistar Institute

Coaching the Pros

Data from the Corporal Michael J. Crescenz Veterans Affairs Medical Center in Philadelphia showed that doctors there were ordering bone scans at three times the national rate for a certain group of prostate cancer patients. It called for a coaching v...

– Perelman School of Medicine at the University of Pennsylvania

Under the Redwoods, UC Santa Cruz Treehouse Initiative Fights Kids’ Cancer Using Computers

The City of Santa Cruz Economic Development Office recently sat down with Treehouse Childhood Cancer Initiative Founder Olena Morozova and UC Santa Cruz Genomics Institute Scientific Director David Haussler to learn more about how UC Santa Cruz is wo...

– University of California, Santa Cruz

Cell Cycle-Blocking Drugs Can Shrink Tumors by Enlisting Immune System in Attack on Cancer, Study Finds

• Study explains why CDK4/6 inhibitors can shrink tumor in some advanced breast cancers • CDK4/6 inhibitors trigger the immune system to attack tumor cells • CDK4/6 inhibitors can also enhance anti-cancer effect of immunotherapy agents

– Dana-Farber Cancer Institute


Embargo expired on 16-Aug-2017 at 13:00 ET

Favorable Safety Profile Seen in Immunotherapy Drug in Aggressive Form of Lung Cancer

The immunotherapy drug pembrolizumab has demonstrated a favorable safety profile and “promising durable clinical activity” in pretreated patients who exhibit high levels of the PD-L1 protein in advanced stages of small cell lung cancer. That is a...

– Rutgers Cancer Institute of New Jersey

Journal of Clinical Oncology, Aug-2017

Embargo expired on 16-Aug-2017 at 16:00 ET

Successful Test of Small-Scale Accelerator with Big Potential Impacts for Science and Medicine

An advanced particle accelerator designed at the U.S. Department of Energy's Brookhaven National Laboratory could reduce the cost and increase the versatility of facilities for physics research and cancer treatment.

– Brookhaven National Laboratory

Embargo expired on 16-Aug-2017 at 07:30 ET

Combination of Traditional Chemotherapy, New Drug Kills Rare Cancer Cells in Mice

An experimental drug combined with the traditional chemotherapy drug cisplatin, when used in mice, destroyed a rare form of salivary gland tumor and prevented a recurrence within 300 days, a University of Michigan study found.

– University of Michigan

Researchers Working on Blood Test to Detect Brain Metastases While Still Treatable

Houston Methodist cancer researchers are now closer to creating a blood test that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response to therapy in real time...

– Houston Methodist

Nature Communications, August 4

Eating Habits Affect Skin’s Protection Against Sun

Sunbathers may want to avoid midnight snacks before catching some rays.

– UT Southwestern Medical Center

Cell Reports

Policy and Public Affairs

ASTRO Supports U.S. Nuclear Regulatory Commission Final Rule

The American Society for Radiation Oncology (ASTRO) applauds the United States Nuclear Regulatory Commission (NRC) for today’s announcement of a final rule that updates the definition of medical events for permanent implant brachytherapy and protec...

– American Society for Radiation Oncology (ASTRO)


Penn Medicine Pharmacologist Given Founders’ Award from American Chemical Society

Ian A. Blair, PhD, an internationally recognized expert on applying mass spectrometry, has won the 2017 Founders’ Award from the Division of Chemical Toxicology of the American Chemical Society.

– Perelman School of Medicine at the University of Pennsylvania

$729K American Cancer Society Grant Awarded to Rutgers Cancer Institute Researcher

Jennifer Tsui, PhD, a researcher at Rutgers Cancer Institute of New Jersey, has been awarded a $729,000 Mentored Research Scholar Grant in Applied and Clinical Research (MRSG-17-099-01-CPHSPS) from the American Cancer Society to further explore healt...

– Rutgers Cancer Institute of New Jersey


DoD Gives SBP Scientist Career Development Award for Pancreatic Cancer Research

Assistant professor aims to identify drugs that deplete tumors of nutrition.

– Sanford Burnham Prebys Medical Discovery Institute

CWRU Awarded Funding to Understand How A Virus-Like Particle from Plants Stimulates Potent Anti-Tumor Response

Nicole Steinmetz, PhD, Associate Professor of Biomedical Engineering, Radiology, member of the Case Comprehensive Cancer Center and the Center for RNA Science and Therapeutics in the Division of General Medical Sciences at Case Western Reserve Univer...

– Case Western Reserve University

National Institutes of Health; U01 Award, National Cancer Institute

NCCN Guidelines to Be Integrated Into the Evinance Decision Support Platform

Integration of the NCCN Content into the Evinance Decision Support Platform will provide clinicians with access to the latest evidence-based treatment information at the point of care.

– National Comprehensive Cancer Network® (NCCN®)

$4 Million in Multi-Source Support Aids DNA Repair Research by Rutgers Cancer Institute of New Jersey and National Cancer Institute Investigators

Rutgers Cancer Institute of New Jersey and the National Cancer Institute’s Center for Cancer Research are collaborating on work examining DNA repair in cancer thanks to $4 million in support including $2 million from the Robert Wood Johnson Foundat...

– Rutgers Cancer Institute of New Jersey

Cancer Genetics Expert Katherine L. Nathanson, MD, Named Deputy Director of Abramson Cancer Center

Katherine L. Nathanson, MD, an internationally recognized expert in the field of cancer genetics, has been named deputy director of the Abramson Cancer Center of the University of Pennsylvania.

– Perelman School of Medicine at the University of Pennsylvania

Breast Cancer Specialist, Dr. Carlos L. Arteaga, to Head UT Southwestern’s Simmons Comprehensive Cancer Center

Dr. Carlos L. Arteaga, internationally recognized for his work in laboratory-based translational research and advancing the care of breast cancer patients, has been selected as Director of the Harold C. Simmons Comprehensive Cancer Center at UT South...

– UT Southwestern Medical Center

NYU Dental Researchers Awarded NIH Grant for Microbiome Research to Identify Biomarkers for Tongue Cancer

The research focuses on the oral microbiome and disruptions in its normal balance, using next-generation sequencing, new molecular technologies which now permit far more comprehensive analyses of the bacterial community in the mouth. Researchers aim...

– New York University

New Data Resource Centre Will Help Better Understand Links Between Birth Defects and Childhood Cancer

Up to $14.8 million over five years, contingent on available funds, was announced today by The National Institutes of Health (NIH) Common Fund’s Gabriella Miller Kids First Pediatric Research Program (Kids First). Researchers in Canada and the Unit...

– Ontario Institute for Cancer Research

Embargo expired on 15-Aug-2017 at 12:05 ET

New Genomic Data Platform to Focus on Children’s Health Issues

Investigators from the University of Chicago Medicine will play a central role in a five-year, $14.8 million effort by the National Institutes of Health, contingent upon available funding, to improve the understanding of inherited diseases.

– University of Chicago Medical Center

CHLA Researcher Awarded $1.9 Million by NIH to Study Novel Approach to Battling Neuroblastoma

Muller Fabbri, MD, PhD, of the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles, has been awarded $1.9 million by the National Cancer Institute of the NIH to further his research on neuroblastoma.

– Children's Hospital Los Angeles Saban Research Institute


Higher Education Events

Cowboys for Cancer Research Celebrates 35 Years of Supporting New Mexicans

Cowboys for Cancer Research will hold its 35th annual dinner, dance and silent auction fundraising event to raise money and awareness for cancer research at The University of New Mexico Comprehensive Cancer Center and at New Mexico State University. ...

– University of New Mexico Comprehensive Cancer Center

Expert Pitch

Expert Discusses Future in Metastatic Lung Cancer Treatment

– Yale Cancer Center





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