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Newswise Special Wire
Wednesday, September 6, 2017

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Newswise Cancer Research Wire for 06-Sep-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Liver Cancer Patients Can Start with Lower Dose of Chemotherapy and Live Just as Long

Patients with the most common type of liver cancer who are taking the chemotherapy drug sorafenib can begin their treatment with a lower dose than is currently considered standard, and it will not affect how long they live when compared to patients w...

– Perelman School of Medicine at the University of Pennsylvania

Journal of Clinical Oncology

Employees Not Aware of Prolonged Sitting Risks

It is estimated that employees spend more than half their day sitting down. A recent study has found that this could lead to serious health problems such as cancer, heart disease and diabetes.

– Leeds Beckett University

Zika Virus Kills Brain Cancer Stem Cells

While Zika virus causes devastating damage to the brains of developing fetuses, it one day may be an effective treatment for glioblastoma, a deadly form of brain cancer. New research from Washington University School of Medicine in St. Louis and the ...

– Washington University in St. Louis

The Journal of Experimental Medicine, Sep-2017; R01 AI073755; R01 AI104972; CA197718; CA154130; CA169117; CA171652; NS087913; NS089272

Embargo expired on 05-Sep-2017 at 09:00 ET

Vaccine to Prevent Most Cervical Cancers Shows Long-Term Effectiveness

A vaccine that can literally eradicate the majority of cervical cancer cases shows long-term effectiveness in a study published today in The Lancet. This study in 18 countries extends the initial phase 3 efficacy and safety trial of the nine-valent h...

– University of Alabama at Birmingham

The Lancet

Embargo expired on 05-Sep-2017 at 18:30 ET

Research Reveals Gene Differences in Mouse Model Versus Humans

Aspects of gene function in humans can be predicted by studies of the corresponding gene in mice, but new research findings have revealed important divergences between the species which scientists will need to understand better through further invest...

– Sbarro Health Research Organization (SHRO)


Exploring Immunotherapy for Carcinoid and Pancreatic Neuroendocrine Tumors

A clinical trial testing the immunotherapy drug pembrolizumab shows the drug to be well tolerated among patients who have carcinoid or pancreatic neuroendocrine tumors. That’s according to investigators at Rutgers Cancer Institute of New Jersey an...

– Rutgers Cancer Institute of New Jersey

ESMO 2017 Congress

Young and Female: A Good Combination for Kidney Health?

Young females may have the greatest level of protection against acute kidney injury (AKI) caused by the chemotherapy drug Cisplatin, commonly used to treat lung, ovarian, bladder and stomach cancer. Nearly a third of all people who are treated with C...

– American Physiological Society (APS)

Penn’s Glowing Cancer Tool Illuminates Benign, but Dangerous, Brain Tumors during Pituitary Surgery

An experimental imaging tool that uses a targeted fluorescent dye successfully lit up the benign brain tumors of patients during removal surgery, allowing surgeons to identify tumor tissue, a new study from researchers at the Perelman School of Medic...

– Perelman School of Medicine at the University of Pennsylvania

Journal of Neurosurgery, Aug-2017; R01 CA193556; UL1TR000003

Combined DNA and Protein ‘Liquid Biopsy’ for Early Pancreatic Cancer Better Than Either Alone

Johns Hopkins scientists say they have developed a blood test that spots tumor-specific DNA and protein biomarkers for early-stage pancreatic cancer.

– Johns Hopkins Medicine

Proceedings of the National Academy of Sciences; APP1060804, P30-CA006973, CA062924, CA102701, CA06973, CA152753, GM-07309, CA152753

Embargo expired on 04-Sep-2017 at 15:00 ET

Palliative Care Makes Only Limited Gains in Africa

Icahn School of Medicine at Mount Sinai student leads first comprehensive analysis of African palliative care literature over past 12 years

– Mount Sinai Health System

Lancet Oncology

Embargo expired on 01-Sep-2017 at 18:30 ET

X-Ray Footprinting, Brain Development, Sleep Research, and More in the Cell Biology News Source

The latest research and features in cell biology in the Cell Biology News Source

– Newswise

Physician Experts Highlight Research ahead of Otolaryngology’s Annual Meeting

The latest research on patient preferences, quality-of-life, ear health, thyroidectomy, and other topics related to the specialty of otolaryngology will be presented in Chicago, IL, September 10-13, during the AAO-HNSF 2017 Annual Meeting & OTO Exper...

– American Academy of Otolaryngology - Head and Neck Surgery

Study: Drug May Curb Female Infertility From Cancer Treatments

An existing drug may one day protect premenopausal women from life-altering infertility that commonly follows cancer treatments, according to a new study.

– Cornell University


Mayo Clinic Monthly News Tips - August 2017 Headlines

Balancing school and sleep; Researchers report link between cells associated with aging and bone loss; Discovery of new prostate cancer biomarkers could improve precision therapy...

– Mayo Clinic

Mayo Clinic Researchers Identify Genes Fueling Neuroblastoma Spread

For the first time, Mayo Clinic researchers and colleagues present data on how nervous system tumors, called neuroblastomas, spread. Their paper, published in Cancer Cell, clarifies the relationship between two genes that fuel the aggressive spread ...

– Mayo Clinic

Cancer Cell

Ovarian Cancer Patients Receive Individualized Care Through Comprehensive Program for Mind, Body and Soul

UAB provides ovarian cancer care beyond traditional interventions to include nutrition, supportive care, counseling and genetic testing.

– University of Alabama at Birmingham

New Approach to Genetic Testing Matches Lung Cancer Patient with Life-Saving Drug

A University of Colorado Cancer Center case study published today in the journal JCO Precision Oncology tests for alterations in many genes simultaneously, matching stage IV lung cancer patient with life-saving drug

– University of Colorado Cancer Center

JCO Precision Oncology

Key Factor Identified in Gene Silencing

Hengbin Wang and colleagues describe a key role for a protein called RSF1 in silencing genes. Besides the molecular biology details, the researchers also showed that disruption of RSF1 expression in the embryos of African clawed frogs caused severe d...

– University of Alabama at Birmingham

Proceedings of the National Academy of Sciences; GM081489 ; GM098539; 2016533; 91440116

Z-endoxifen Shows Promise as New Treatment for Common Breast Cancer Type

Z-endoxifen, a potent derivative of the drug tamoxifen, could itself be a new treatment for the most common form of breast cancer in women with metastatic disease. This finding was reported from a clinical trial conducted by researchers at Mayo Clini...

– Mayo Clinic

Journal of Clinical Oncology

Beta Blockers May Hold Key to Unleashing Potential of Checkpoint Inhibitors, Roswell Park Team Shows

In new research published in the journal Cancer Research, a team from Roswell Park has shown that "beta blocker" drugs appear to be an effective means of reducing beta-2 receptor signaling and, in the process, may improve the efficacy of checkpoin...

– Roswell Park Cancer Institute

Cancer Research; T32CA085183; R01CA140622; P30CA016056

An Innovative Whole-Breast Ultrasound Technology Could Be Life-Saving for Women with Dense Breast Tissue

USC Norris Comprehensive Cancer Center is the first site actively recruiting for a clinical trial researching a new, gentle, automated technology for imaging dense breasts.

– Keck Medicine of USC

FDA Approves Personalized Cellular Therapy for Advanced Leukemia Developed by University of Pennsylvania and Children’s Hospital of Philadelphia

In a landmark decision for the field of cancer immunotherapy, the U.S. Food and Drug Administration (FDA) today approved a personalized cellular therapy developed by the University of Pennsylvania and Children’s Hospital of Philadelphia (CHOP) for ...

– Perelman School of Medicine at the University of Pennsylvania

UChicago Medicine Working to Offer Breakthrough CAR T-Cell Gene Therapy Approved Today by FDA

The University of Chicago Medicine is one of a limited number of U.S. sites working to offer a breakthrough gene therapy for pediatric acute lymphoblastic leukemia (ALL), which was just approved by the U.S. Food and Drug Administration.

– University of Chicago Medical Center

Expanding the Reach of Therapeutic Antibodies

A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy. The details will be published in the Se...

– American Society for Biochemistry and Molecular Biology (ASBMB)

Journal of Biological Chemistry, Aug 2017

Two-Stage Approach to Risk-Reducing Mastectomy Improves Results for Women with Large Breasts


– Wolters Kluwer Health: Lippincott Williams and Wilkins

Plastic and Reconstructive Surgery


Innovative Study Brings Next-Generation Genomic Sequencing to More Ontario Cancer Patients

Understanding a cancer’s genetics is key to selecting targeted therapies that are likely to be of the most benefit to a patient. The Ontario Institute for Cancer Research (OICR) today announced a new study, called Ontario-wide Cancer TArgeted Nucle...

– Ontario Institute for Cancer Research

Radiation Oncology Institute’s Inaugural Publication Awards Honor Radiation Oncology Researchers

The Radiation Oncology Institute (ROI) announced today the winners of its inaugural publication awards, which recognize research on the value of radiation therapy for improving cancer outcomes.

– Radiation Oncology Institute

Evinance to Integrate its Decision Support Technology in Varian Oncology Care Management Platform

Evinance Innovation Inc. and Varian Medical Systems (NYSE: VAR) announced today that the Evinance Decision Support platform will be integrated within Varian’s 360 Oncology™ care management platform.

– Evinance Innovation Inc.

Outstanding Investigator Grant Awarded to Dario C. Altieri, M.D., Wistar President and CEO

The Wistar Institute is pleased to announce that distinguished scientist Dario C. Altieri, M.D., Wistar president and CEO and director of the Institute’s Cancer Center, has been awarded an Outstanding Investigator Grant (R35) by the National Instit...

– Wistar Institute

Internationally Recognized Surgeon Named Chief Surgical Officer at Rutgers Cancer Institute of New Jersey

Expanding its surgical and research focus on cancers of the abdominal area and rare conditions including endocrine and mesothelioma malignancies, Rutgers Cancer Institute of New Jersey has named H. Richard Alexander, MD, FACS, as its new chief surgic...

– Rutgers Cancer Institute of New Jersey

Mercy Medical Center Earns Joint Commission Certification in Uterine & Ovarian Cancer

Mercy Medical Center has achieved initial certification in Uterine and Ovarian Cancer Care from The Joint Commission, Disease-Specific Care Certification process. Mercy is the first hospital in Maryland to achieve Uterine and Ovarian Cancer care cert...

– Mercy Medical Center, Baltimore

Investigating the Mechanisms of Metastasis

To understand metastasis, Yves DeClerck, MD, of Children’s Hospital Los Angeles has studied the tumor microenvironment for his entire career. He has recently been awarded $2.2 million from the National Cancer Institute, to investigate the microenvi...

– Children's Hospital Los Angeles Saban Research Institute

Wolters Kluwer and the European Society of Oncology Pharmacy Launch the European Journal of Oncology Pharmacy

Wolters Kluwer Health and the European Society of Oncology Pharmacy (ESOP) today announced the launch of a new open access journal, the European Journal of Oncology Pharmacy (EJOP). The official journal of the ESOP will join the Lippincott portfolio ...

– Wolters Kluwer Health: Lippincott Williams and Wilkins

European Journal of Oncology

Dr. Peter Glazer Receives Prestigious Outstanding Investigator Award for Cancer Research

The National Cancer Institute (NCI) has named Peter M. Glazer, M.D., Ph.D., as a recipient of its Outstanding Investigator Award (OIA).

– Yale Cancer Center

Dr. Pawel Muranski to Head New Cellular Immunotherapy Laboratory at NewYork-Presbyterian/Columbia University Medical Center

Dr. Pawel Muranski has joined NewYork-Presbyterian and Columbia University Medical Center (CUMC) as director of cellular immunotherapy at the newly established Good Manufacturing Practices (GMP) cell production lab and assistant director of Transfusi...

– New York-Presbyterian Hospital

ASTRO honors 43 researchers with Abstract Awards at its 2017 Annual Meeting

The American Society for Radiation Oncology (ASTRO) has selected 43 recipients to be presented with one of its 2017 Annual Meeting Abstract Awards.

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting September 24-27

The University of Kansas Cancer Center and Children’s Mercy Receive Grant to Advance Childhood Cancer

Braden’s Hope announced it will be awarding $3 million to advance childhood cancer research at The University of Kansas Cancer Center and Children’s Mercy. Braden’s Hope is a Kansas City-based charity that raises awareness and funds for precisi...

– University of Kansas Cancer Center

Higher Education Events

Legendary Music Executive/Record Producer Clive Davis, Marty Bandier and Music and Entertainment VIPs to Celebrate at 13th Annual Songs of Hope Event on Sept. 28

Max Martin, Hans Zimmer, Jack Antonoff and the Chainsmokers announced as honorees for Songs of Hope XIII — benefiting City of Hope.

– City of Hope

Expert Pitch

FDA's CTL019 Ruling Validates Importance of Similar Lifesaving Cellular Immunotherapies Currently Being Developed and Tested by Fred Hutch and Other NCI-Designated Cancer Centers

– Fred Hutchinson Cancer Research Center

UPMC Hillman Cancer Center immunology expert available to talk about FDA approval of CAR - T cell therapy.

– Health Sciences at the University of Pittsburgh

Dr. Bishop @Uchicagomed Knows CAR T-Cell Therapy Backward and Forward

– University of Chicago Medical Center





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