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Newswise Special Wire
Tuesday, September 12, 2017

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Newswise Cancer Research Wire for 12-Sep-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Mayo Clinic National Health Checkup: Nearly All Americans Take at Least One Preventive Measure to Avoid Cancer

Cancer is a real concern for many Americans. According to the fourth edition of the Mayo Clinic National Health Checkup, 95 percent of respondents take at least one preventive measure to avoid cancer.

– Mayo Clinic

Embargo expired on 12-Sep-2017 at 05:30 ET

Doctors Can Now Predict the Severity of Your Disease by Measuring Molecules

The simple new technique could offer vastly superior predictions of disease severity in a huge range of conditions with a genetic component, including Alzheimer’s, autism, cancer, cardiovascular disease, diabetes, obesity, schizophrenia and depress...

– University of Virginia Health System

Small; NS065183; NS089578; NS053570; NS091452; NS094980; NS092548

SLU Researcher Discovers How Hibernating Ribosomes Wake Up

Saint Louis University scientist Mee-Ngan F. Yap, Ph.D.,has uncovered the way a bacterial ribosome moves from an inactive to an active form, and how that "wake up call" is key to its survival.

– Saint Louis University Medical Center

Proceedings of the National Academy of Sciences (PNAS); R01GM121359

Accelerating the Development of Next-Generation Cancer Therapies

The Gene Editing Institute of Christiana Care’s Helen F. Graham Cancer Center & Research Institute signs agreement with ABS to modify cell lines to accelerate cancer therapies

– Christiana Care Health System

Cell Surface Protein May Offer Big Target in Treating High-Risk Childhood Cancers

Oncology researchers studying high-risk children’s cancers have identified a protein that offers a likely target for immunotherapy--harnessing the immune system in medical treatments. In cell cultures and animal models, a potent drug attached to an...

– Children's Hospital of Philadelphia

Cancer Cell, online Sept. 11, 2017; CA009615, GM008638

Embargo expired on 11-Sep-2017 at 12:05 ET

A Newly Identified Mitochondrial Metastasis Suppressor Pathway Controls Metabolic Reprogramming of Tumor Cells

A novel mitochondrial variant of the protein Syntaphilin, or SNPH, which orchestrates the choice between cancer cell proliferation and metastasis in response to oxygen and nutrient shortage in the tumor microenvironment, has been identified by resear...

– Wistar Institute

Journal of Clinical Investigation

Embargo expired on 11-Sep-2017 at 16:00 ET

Savings Less Than Expected for Generic Oral Chemotherapy

Cost savings fell below expectations for generic versions of an orally administered cancer treatment in an analysis by University of North Carolina Lineberger Comprehensive Cancer Center researchers. The findings raise questions about the extent to w...

– University of North Carolina Health Care System

JAMA Internal Medicine, Sept-2017

Embargo expired on 11-Sep-2017 at 11:00 ET

Modulating T-Cell Metabolism Uncovers New Technology for Enhancing Immunotherapy

T lymphocytes found in tumors and implicated in killing tumor cells cope with the shortage of oxygen and nutrients in the tumor microenvironment by using fat as the main source of energy. Promoting a switch from glucose to fatty acid to generate ener...

– Wistar Institute

Cancer Cell

Embargo expired on 11-Sep-2017 at 12:00 ET

Revolutionary Process Could Signal New Era for Gene Synthesis

A team of scientists led by the University of Southampton has demonstrated a groundbreaking new method of gene synthesis – a vital research tool with real-world applications in everything from growing transplantable organs to developing treatments ...

– University of Southampton

Nature Chemistry, Sept-2017

Embargo expired on 11-Sep-2017 at 11:00 ET

Checking Your Neck, Colon Cancer Screening, New Microfluidic Device, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

– Newswise

Does Health Insurance Status Affect Childhood Cancer Survival?

Privately insured children and those with Medicaid at the time of a cancer diagnosis experience largely similar survival trends, with slight evidence for an increased risk of cancer death in children who were uninsured at diagnosis, finds a new study...

– Washington University in St. Louis


UCLA opens first engineered blood stem cell clinical trial for cancers with the NY-ESO-1 tumor marker

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have initiated a phase 1 clinical trial to test a novel cancer treatment for certain kinds of cancers that have a specific tumor marker called NY-ES...

– University of California, Los Angeles (UCLA), Health Sciences

Alternative Immunotherapy Drug More Effective than Current Standard of Care in Treating Advanced Melanoma after Surgical Removal of Disease

The immunotherapy drug nivolumab is safer and more effective than ipilimumab—the current standard of care—in treating patients with resected stage III and stage IV melanoma.

– NYU Langone Health

NEJM; ESMO Sept-2017

Embargo expired on 10-Sep-2017 at 18:05 ET

Letters, FIT Kits Can Triple Colon Cancer Screening Rates

Sending a letter and, in some cases, a simple mail-in kit tripled colon cancer screening completion among low-income adults, researchers at UT Southwestern’s Simmons Cancer Center report this week in JAMA.

– UT Southwestern Medical Center


Genome Sequence Is Not a Predictor of Radiation Resistance

Bethesda, Md. – For the last two decades, researchers worldwide have been using whole genome sequencing to understand what makes cells radiation-resistant, hoping to solve an old biological mystery: why is it that one of the most radiation-resistan...

– Uniformed Services University of the Health Sciences (USU)

Standards of Genomic Sciences

Study Unlocks How Changes in Gene Activity Early During Therapy Can Establish the Roots of Drug-Resistant Melanoma

A UCLA-led study of changes in gene activity in BRAF-mutated melanoma suggests these epigenomic alterations are not random but can explain how tumors are already developing resistance as they shrink in response to treatment with a powerful class of d...

– University of California, Los Angeles (UCLA), Health Sciences

Cancer Discovery

New Link Established Between a Molecular Driver of Melanoma Progression and Novel Therapeutic Agent

Wistar scientists have described a correlation between a key melanoma signaling pathway and a novel class of drugs being tested in the clinic as adjuvant therapy for advanced melanoma, providing useful information for a more effective use of this typ...

– Wistar Institute

Cancer Research; Melanoma Research Alliance/L’Oréal Paris-USA Women in Science Team Science Award; Adelson Medical Research Foundation; Ira Brind Associate Professorship to Weeraratna...

Embargo expired on 07-Sep-2017 at 00:05 ET

Adding Modified Herpes Virus to Immunotherapy Shows Promise for Treating Advanced Melanoma

In a two-year study at UCLA, nearly two-thirds of people with advanced melanoma responded positively to a treatment that combines the immunotherapy drug pembrolizumab with a herpes virus called talimogene laherpareovec, or T-VEC. Researchers led by ...

– University of California, Los Angeles (UCLA), Health Sciences


Check Your Neck!

There are approximately 57,000 newly diagnosed thyroid cancers annually. Do you know the signs and symptoms? A Rutgers Cancer Institute of New Jersey expert shares more.

– Rutgers Cancer Institute of New Jersey

Blood Tumor Markers May Warn When Lung Cancer Patients Are Progressing on Targeted Treatments

University of Colorado Cancer Center study shows that monitoring levels of blood tumor markers may predict when a lung cancer patient is progressing on targeted treatments.

– University of Colorado Cancer Center

Journal of Thoracic Oncology

New Study Finds Improved Vaccine That Protects against Nine Types of HPV is Highly Effective

TAMPA, Fla. – Cervical cancer is the second most common cause of cancer-related death worldwide, with almost 300,000 deaths occurring each year. More than 80 percent of these deaths occur in developing nations. The advent of human papillomavirus (H...

– Moffitt Cancer Center

The Lancet

The Medical Minute: Helping Children Thrive After Cancer

Childhood cancer survivors are at a higher risk of developing physical and emotional difficulties once their treatment is complete. That's why it’s important to connect them with follow-up care and resources.

– Penn State Health Milton S. Hershey Medical Center


Penn Cancer Biologist Given National Cancer Institute Outstanding Investigator Award

M. Celeste Simon, PhD, who studies cancer cell metabolism, tumor immunology, and the influence of oxygen availability and deprivation on tumor growth, has been given a National Cancer Institute Outstanding Investigator Award.

– Perelman School of Medicine at the University of Pennsylvania

NCCN Announces First Patient Dosed in NCCN-Peregrine Pharmaceuticals Collaborative Study of Bavituximab

An NCCN ORP-funded study, examining effectiveness of bavituximab combination in patients with newly diagnosed glioblastomas, enrolled its first patient at Dana-Farber Cancer Institute in Boston, Massachusetts.

– National Comprehensive Cancer Network® (NCCN®)

NCCN Chemotherapy Order Templates to be Integrated into MEDITECH’s Web EHR

Providing access to NCCN Templates® through MEDITECH’s Web EHR offers practitioners up-to-date, evidence-based cancer treatment protocols at the point of care to assist in shared decision-making.

– National Comprehensive Cancer Network® (NCCN®)

Mercy Medical Center's Dr. Armando Sardi Supports Partners for Cancer Care & Prevention with Annual Golf Tournament

8th Annual Chipping for Cancer Care and Prevention Golf Tournament, on Friday, Sept. 15th at the Waverly Woods Golf Club in Marriottsville, MD, supports efforts of Partners for Cancer Care and Prevention non-profit organization.

– Mercy Medical Center, Baltimore





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