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Newswise Special Wire
Tuesday, September 26, 2017

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Newswise Cancer Research Wire for 26-Sep-2017
 

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.



ACA Medicaid Expansion Cut Disparities in Cancer Care for Minorities, Poor

States that fully expanded their Medicaid programs under the Affordable Care Act cut their rates of uninsured cancer patients by more than half between 2011 and 2014. Black patients and those living in the highest poverty areas saw the greatest benef...

– Duke Health

Embargo expired on 26-Sep-2017 at 10:45 ET


Uninsured Cancer Patients Saw Increased Coverage for Care Following Medicaid Expansion

A new study finds that Medicaid expansion enacted as part of the Patient Protection and Affordable Care Act (ACA) improved coverage for care for cancer patients receiving radiation therapy and potentially decreased health care disparities.

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017

Embargo expired on 26-Sep-2017 at 10:45 ET


UNM Cancer Center Plays Key Role in First-in- Human Testing of New Cancer Drug

The UNM Comprehensive Cancer Center played a key role in the first clinical trials of a new drug that targets solid cancer tumors. The Phase 1A clinical trials mark the first time ever the drug, called BXQ-350, was used in people. BXQ-350 is compris...

– University of New Mexico Comprehensive Cancer Center

Embargo expired on 26-Sep-2017 at 05:05 ET


New Payment Models for Radiation Therapy Should Consider Impact of Behavioral Health Costs Mayo Researchers Say

.Efforts to develop new payment models in radiation oncology also should consider measures to address behavioral health to reduce the total cost of care during and after radiotherapy, according to the results of study performed by researchers at Mayo...

– Mayo Clinic

embargoed until 26-Sep-2017, 13:00 ET


Drug Combo Gangs Up to Take on Triple-Negative Breast Cancer

In the hunt for novel treatments against an aggressive form of breast cancer, researchers combined a new protein inhibitor with a chemotherapy drug to create a powerful combination that resulted in cancer cell death.

– Michigan Medicine - University of Michigan

Oncotarget; GM097220


Breast Cancer Patients Largely Find Radiation Therapy Experience Better Than Expected

A new survey finds breast cancer patients’ actual radiation therapy experiences largely exceeded their expectations.

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017

Embargo expired on 25-Sep-2017 at 10:45 ET


MRI Contrast Agent Locates and Distinguishes Aggressive From Slow-Growing Breast Cancer

A new magnetic resonance imaging (MRI) contrast agent being tested by researchers at Case Western Reserve University not only pinpoints breast cancers at early stages but differentiates between aggressive and slow-growing types.

– Case Western Reserve University

Nature Communications; Sept.-2017

Embargo expired on 25-Sep-2017 at 05:00 ET


Halving Radiation Therapy for HPV-Related Throat Cancer Offers Fewer Side Effects and Similar Outcomes, Mayo Study Finds

Mayo Clinic researchers have found that a 50 percent reduction in the intensity and dose of radiation therapy for patients with HPV-related throat cancer reduced side effects with no loss in survival and no decrease in cure rates.

– Mayo Clinic

Embargo expired on 25-Sep-2017 at 15:00 ET


Aggressively Reduced Radiation Therapy for HPV-Related Throat Cancer Achieves Similar Control Rates with Fewer Side Effects

For certain patients with oropharyngeal cancer caused by the human papilloma virus (HPV), an aggressive reduction of radiation therapy after surgery may provide excellent cancer control while simultaneously reducing post-treatment side effects, impro...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017

Embargo expired on 25-Sep-2017 at 14:00 ET


Phase III Trial Confirms Pelvic Radiation as Standard of Care for High-Risk, Early-Stage Endometrial Cancer

In a new phase III trial report from the National Clinical Trial Network group, NRG Oncology, recurrence-free and overall survival rates for women with stage I-II high-risk endometrial cancer were not superior following vaginal cuff brachytherapy plu...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017

Embargo expired on 25-Sep-2017 at 14:00 ET


Overall Cancer Risk Not Increased with Use of Popular Diabetes Medication

People taking a new oral medication for Type 2 diabetes can breathe a sigh of relief concerning suspicions they might be at an increased risk for many types of cancer, according to Indiana University researchers.

– Indiana University

Diabetologia, July-2017


Prostaglandin E1 Inhibits Leukemia Stem Cells

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

– University of Iowa

Cell Stem Cell, Sept-2017; RO1AI112579; R21AI115149; R21AI119160; RO1AI121080; RO1HG006130; P50CA097274


Researchers Identify Gene Variants Linked to a High-Risk Children's Cancer

Pediatric researchers in the Roberts Collaborative for Genetics and Individualized Medicine at Children's Hospital of Philadelphia have identified common gene variants that raise the risk of developing an aggressive form of the childhood cancer neuro...

– Children's Hospital of Philadelphia

Nature Communications, Sept. 18, 2017; HG006830, CA124709


Grant Ushers Delaware to Forefront of Gene Editing Education

The world’s most revolutionary gene editing technology is coming to college classrooms in Delaware, thanks to a $1 million National Science Foundation grant awarded to the Delaware Technical Community College and the Gene Editing Institute of Chris...

– Christiana Care Health System


Adding Radiation to Chemotherapy May Dramatically Improve Survival for Advanced-Stage NSCLC Patients

Combining radiation therapy with chemotherapy for patients with limited metastatic non-small cell lung cancer (NSCLC) may curb disease progression dramatically when compared to NSCLC patients who only receive chemotherapy, according to a new randomiz...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017

Embargo expired on 24-Sep-2017 at 16:00 ET


Distress associated with missed appointments and hospital admission during cancer treatment

Psychological distress has long been associated with negative health outcomes for cancer patients, though specific reasons remain unclear.

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017

Embargo expired on 24-Sep-2017 at 16:15 ET


Long-Term Survival Rates More Than Double Previous Estimates for Locally Advanced Lung Cancer

Long-term results of a phase III clinical trial indicate that survival rates for patients receiving chemoradiation for unresectable, locally advanced non-small cell lung cancer (NSCLC) may be more than twice as high as previous estimates.

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017

Embargo expired on 24-Sep-2017 at 16:00 ET


Study at Urban Cancer Center Finds 75 Percent of Its Depressed Patients Were Previously Undiagnosed

A new study of patients at an urban cancer center points to a potentially serious problem that may limit the impact of clinical cancer care—undiagnosed depression.

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017

Embargo expired on 24-Sep-2017 at 16:15 ET


Radiation-Immunotherapy Combination Can Slow Tumor Growth for Some Patients with Metastatic Late-Stage Cancer

A new study involving patients with stage IV cancer finds that treatment with radiation therapy and immunotherapy can halt the growth of tumors by stimulating the body’s immune system to attack the cancer.

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017

Embargo expired on 24-Sep-2017 at 16:00 ET


International Trial Confirms Safety, Effectiveness of High-Dose Brachytherapy Plus Pelvic Radiation for Cervical Cancer

Findings from a new multicenter, international clinical trial confirm the effectiveness of high-dose brachytherapy, or internal radiation therapy, for managing locally advanced cervical cancer. Tumor control was significantly better following four fr...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Sep-2017


Can Gardening Prevent Cancer?

Public health researchers, armed with a $1 million American Cancer Society grant, have launched one of the first randomized controlled trials ever to study the physical and psychological benefits of community gardening.

– University of Colorado Boulder


Locking Down the Big Bang of Immune Cells

Scientists have found that ignored pieces of DNA play a critical role in the development of immune cells (T cells). These areas activate a change in the structure of DNA that brings together crucial elements necessary for T cell formation. This “bi...

– University of California San Diego

Cell, Sep-2017

Embargo expired on 21-Sep-2017 at 12:00 ET


Targeting a Binding Protein in Mutated p53 Could Yield New Cancer Treatment Strategies

Research by Rutgers Cancer Institute of New Jersey investigators shows the targeting of a binding protein of mutant p53 known as Rac1 could lead to new therapeutic strategies for patients whose cancer carries mutations in the p53 gene.

– Rutgers Cancer Institute of New Jersey

Genes & Development, Sept-2017

Embargo expired on 21-Sep-2017 at 17:00 ET


Breathing Dirty Air May Harm Kidneys

Outdoor air pollution may increase the risk of chronic kidney disease and contribute to kidney failure, Washington University School of Medicine in St. Louis and the Veterans Affairs (VA) St. Louis Health Care System. Scientists culled national VA da...

– Washington University in St. Louis

Journal of the American Society of Nephrology


Scientists Restore Tumor-Fighting Structure to Mutated Breast Cancer Proteins

Scientists at the Virginia Tech Carilion Research Institute have successfully determined the full architecture of the breast cancer susceptibility protein (BRCA1) for the first time. This three-dimensional information provides a potential pathway to ...

– Virginia Tech

Science Advances


Drug Combination May Improve Impact of Immunotherapy in Head and Neck Cancer

Checkpoint inhibitor-based immunotherapy has been shown to be very effective in recurrent and metastatic head and neck cancer but only in a minority of patients. University of California San Diego School of Medicine researchers may have found a way t...

– University of California San Diego Health

JCI Insights


Study Shows Diet and Exercise Improve Treatment Outcomes for Obese Pediatric Cancer Patients

Diet and exercise may improve treatment outcomes in pediatric cancer patients, according to a study at The University of Texas MD Anderson Cancer Center.

– University of Texas M. D. Anderson Cancer Center

Pediatrics Research


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– Newswise


When Good Immune Cells Turn Bad

Investigators at CHLA have identified the molecular pathway used to foster neuroblastoma and demonstrated use of a clinically available agent, ruxolitinib, to block the pathway.

– Children's Hospital Los Angeles Saban Research Institute

Oncotarget, September 2017; CDMRP10669916; W81XWH-12-1-0571; 5U54CA163117


Tibetan Yoga Practice May Improve Sleep Quality for Breast Cancer Patients Receiving Chemotherapy

Participating in twice-weekly practice of Tibetan yoga may reduce sleep disturbances and improve sleep quality in breast cancer patients receiving chemotherapy, according to a study from researchers at The University of Texas MD Anderson Cancer Cente...

– University of Texas M. D. Anderson Cancer Center

Cancer

Embargo expired on 20-Sep-2017 at 10:00 ET


Penn Researchers Identify New Target, Develop New Drug for Cancer Therapies

Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant...

– Perelman School of Medicine at the University of Pennsylvania

Cancer Discovery; R01CA169134; P01 CA114046; P30 CA016520; SPORE P50 CA174523; 1R01CA198015; CA016672; P30CA010815


Altitude Training for Cancer-Fighting Cells

Training at altitude – meaning under low-oxygen conditions – turns athletes into super-performers. Likewise, Prof. Guy Shakhar has found, oxygen-starved T cells become super-effective at attacking cancer. These T cells could provide an immediate ...

– Weizmann Institute of Science

Cell Reports, Sept-2017


How Bacteria Hinder Chemotherapy

Dr. Ravid Straussman and colleagues have discovered that bacteria not only live in pancreatic cancer, but are able to render a chemo drug ineffective. Fortunately, it appears that taking antibiotics allows the chemo to work again.

– Weizmann Institute of Science

Science, Sept-2017


Characterization of a Slowly Proliferating Population of Melanoma Cells with High Metastatic Properties

A study conducted at The Wistar Institute has led to the identification of a slowly proliferating and highly invasive melanoma cell subpopulation, characterized by production of a protein associated with invasive behavior.

– Wistar Institute

Oncogene


Titan Helps Researchers Suck Mystery Out of Cell’s ‘Vacuum Cleaners’

In cancer cells, a membrane transport protein called P-glycoprotein, or Pgp, actively pumps anticancer drugs out of the cell, contributing to multidrug resistance. Recently, a team led by computational biophysicist Emad Tajkhorshid from the Universit...

– Oak Ridge National Laboratory

Nature


New Clinical Trial Explores Combining Immunotherapy and Radiation for Newly Diagnosed Sarcoma Patients

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as wel...

– University of Maryland Medical Center/School of Medicine


October Is Breast Cancer Awareness Month

Mount Sinai Experts Offer Tips on Early Detection, Screening, Understanding Risk and Personalized Treatment Options

– Mount Sinai Health System


Tumor-infiltrating B Lymphocytes Promote Melanoma Progression and Resistance to Therapy

In a multi-institutional collaborative study, scientists at The Wistar Institute and the Medical University of Vienna, Austria, have identified the role of tumor-infiltrating or tumor-associated B-cells (“TABs”) in melanoma progression and resist...

– Wistar Institute

Nature Communications


Brain Powered: Increased Physical Activity Among Breast Cancer Survivors Boosts Cognition

It is estimated that up to 75 percent of breast cancer survivors experience problems with cognitive difficulties following treatments, perhaps lasting years. Currently, few science-based options are available to help. University of California San Die...

– University of California San Diego Health

Cancer


Ovarian Cancer: Risk Factors, Symptoms, Diagnosis and Treatment

Ovarian cancer is the 9th most common cancer in women and although it only accounts for approximately 3 percent of cancers in women, it is responsible for the most deaths of any cancer involving the female reproductive tract. The American Cancer Soci...

– Valley Health System


Announcements


Hackensack Meridian Health Riverview Medical Center Laboratory Receives Accreditation from College of American Pathologists

The laboratory at Hackensack Meridian Health Riverview Medical Center is pleased to announce that it has again received accreditation from the American College of Pathologists (CAP), marking 42 years of accreditation for this vital hospital service. ...

– Hackensack Meridian Health


Hackensack Meridian Health Riverview Medical Center Earns ACR Lung Cancer Screening Center Designation

Hackensack Meridian Health Riverview Medical Center has been designated a Lung Cancer Screening Center by the American College of Radiology (ACR). The ACR Lung Cancer Screening Center designation is a voluntary program that recognizes facilities that...

– Hackensack Meridian Health


“Top Docs” Raise the Bar at UC San Diego Health

More than 100 physicians from UC San Diego Health were named “Top Docs” in the annual <i>San Diego Magazine</i> “Physicians of Exceptional Excellence” annual survey. These physicians represent 45 diverse specialties, from infectious disease, ...

– University of California San Diego Health


UTSW Lung Cancer Researcher Named NCI Outstanding Investigator

The National Cancer Institute (NCI) has selected UT Southwestern Medical Center cancer researcher Dr. Ralph DeBerardinis to receive its prestigious Outstanding Investigator Award. The award includes annual funding of $600,000 for seven years to suppo...

– UT Southwestern Medical Center


UPMC Invests in Private Rome Hospital, Plans Expansion of Specialized Services

UPMC has taken a 50 percent stake in Salvator Mundi International Hospital and will expand specialized services.

– Health Sciences at the University of Pittsburgh


Penn First in World to Treat Patient with New Radiation Technology

Doctors at Penn Medicine have become the first in the world to treat a patient with a new treatment platform designed to streamline the way therapeutic radiation is delivered to cancer patients.

– Perelman School of Medicine at the University of Pennsylvania


Mount Sinai Queens Opens a Satellite of the Head and Neck and Thyroid Institute

Patients in Queens now have access to high quality, advanced medical care for a wide range of ear, nose, and throat (ENT) conditions at Mount Sinai Doctors Queens

– Mount Sinai Health System


UAB Adopts Innovative Imaging Agent to Improve Detection of Certain Bladder Cancers

A blue-light cystoscopy may detect certain bladder cancer tumors more than the use of standard white-light diagnostic testing.

– University of Alabama at Birmingham


Susan Burke Introduced as New President of the Association of Pediatric Hematology/Oncology Nurses

Chicago (Sept. 20, 2017): The Association of Pediatric Hematology/Oncology Nurses (APHON) elected Susan Burke, MA RN CPNP CPHON®, to serve as President for the 2017-2019 term. Burke officially took office at the recent 41st Annual APHON Conference a...

– Association of Pediatric Hematology/Oncology Nurses (APHON)


Association of Pediatric Hematology/Oncology Nurses Announces Jami Gattuso as the 2017 Dr. Casey Hooke Distinguished Service Award Recipient

Chicago (Sep. 20, 2017): The Association of Pediatric Hematology/Oncology Nurses (APHON) has presented Jami Gattuso, MSN RN CPON® with the 2017 Dr. Casey Hooke Distinguished Service Award. Gattuso received her award at the 41st APHON Annual Conferen...

– Association of Pediatric Hematology/Oncology Nurses (APHON)


Association of Pediatric Hematology/Oncology Nurses Announces Dianne Fochtman as the winner of the 2017 Dr. Nancy E. Kline Mentoring Award

Chicago (Sep. 20, 2017): The Association of Pediatric Hematology/Oncology Nurses (APHON) has awarded Dianne Fochtman, PhD RN CPNP CHPPN CPON® with the 2017 Dr. Nancy E. Kline Mentoring Award. This award was presented to Fochtman at the 41st Annual ...

– Association of Pediatric Hematology/Oncology Nurses (APHON)


Association of Pediatric Hematology/Oncology Nurses Announces Amy Haskamp, MSN CNS RN CPON® winner of the 2017 Dr. Patricia Greene Leadership Award

Chicago (Sep. 20, 2017): The Association of Pediatric Hematology/Oncology Nurses (APHON) has awarded this year’s Dr. Patricia Greene Leadership Award to Amy Haskamp, MSN CNS RN CPON®. Haskamp was presented with this award at the 41st Annual APHON ...

– Association of Pediatric Hematology/Oncology Nurses (APHON)


APHON Announces the 2017 Membership Award Winners at its 41st Annual Conference

Chicago (Sep. 20, 2017) The Association of Pediatric Hematology/Oncology Nurses (APHON) announced the recipients of the 2017 APHON Membership Awards at its 41st Annual Conference and Exhibit, held August 17-19 in Palm Springs, CA. APHON Membership Aw...

– Association of Pediatric Hematology/Oncology Nurses (APHON)


CPRIT Awards $34M to UTSW for Cancer Research, Recruitment

The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded UT Southwestern researchers more than $34 million for cancer research and faculty recruitment, including support for programs in pancreatic cancer, lung cancer, breast cancer, ...

– UT Southwestern Medical Center


Higher Education Events


Nation’s Experts in Hematologic Malignancies to Discuss Latest Treatment Advances and Examine Patient Cases during NCCN 12th Annual Congress

NCCN 12th Annual Congress: Hematologic Malignancies™ will be held October 6 – 7, 2017 in San Francisco, California, and features a new Nursing Forum.

– National Comprehensive Cancer Network® (NCCN®)

12th Annual Congress: Hematologic Malignancies™


Over 4,000 Patients, Caregivers and Staff Join John Theurer Cancer Center’s 9th Annual Celebrating Life and Liberty Event

On Sunday, September 10, John Theurer Cancer Center at Hackensack Meridian Health Hackensack University Medical Center, one of the nation’s leading hospitals for cancer, celebrated its largest and most successful Celebrating Life and Liberty event ...

– Hackensack Meridian Health


Marketplace


MD Anderson Cancer Center and Pfizer Oncology Announce Clinical Collaboration to Evaluate Immuno-Oncology Combinations in Blood Cancers and Solid Tumors

The University of Texas MD Anderson Cancer Center and Pfizer Inc. today announced that they have entered into a clinical collaboration to study novel combinations of three Pfizer investigational immuno-oncology therapies and other Pfizer agents in t...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 26-Sep-2017 at 07:00 ET


Expert Pitch


Backed by Yale Cancer Center Research, FDA Approves New Immunotherapy Drug for Stomach Cancer

– Yale Cancer Center

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