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Newswise Special Wire
Tuesday, October 10, 2017

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Newswise Cancer Research Wire for 10-Oct-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

In Global First, Penn Using Glowing Tumor Dye to Identify Cancerous Lymph Nodes

Surgeons at Penn Medicine are using a fluorescent dye that makes cancerous cells glow in hopes of identifying suspicious lymph nodes during head and neck cancer procedures. Led by Jason G. Newman, MD, FACS, an associate professor of Otorhinolaryngolo...

– Perelman School of Medicine at the University of Pennsylvania

1F32CA210409; R01 CA193556

Areas of Glioblastoma Tumors Correlate with Separate Subtypes of Glioma Stem Cells, Respond Better to Combination Treatment

Study in journal Nature Medicine demonstrates, for the first time, that glioblastoma (GBM) is driven by two distinct subsets of cancer stem cells. Moreover, each subtype of glioma stem cells is driven by distinct transcriptional programs for growth ...

– University Hospitals Cleveland Medical Center

Nature Medicine

Novel Treatment Causes Cancer to Self-Destruct Without Affecting Healthy Cells

Scientists at Albert Einstein College of Medicine have discovered the first compound that directly makes cancer cells commit suicide while sparing healthy cells. The new treatment approach, described in today’s issue of Cancer Cell, was directed ag...

– Albert Einstein College of Medicine

Cancer Cell; R01CA178394

Embargo expired on 09-Oct-2017 at 12:00 ET

Liquid Biopsy May Be New Way to Detect Liver Cancer Earlier, Easier

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and ...

– University of California San Diego Health

Nature Materials

Embargo expired on 09-Oct-2017 at 11:00 ET

Combination Treatment Targeting Glucose in Advanced Brain Cancer Shows Promising Results in Preclinical Study

UCLA scientists have discovered a potential combination treatment for glioblastoma, the deadliest form of brain cancer in adults. The three-year study led by Dr. David Nathanson, a member of UCLA's Jonsson Comprehensive Cancer Center, found that the ...

– University of California, Los Angeles (UCLA), Health Sciences

Nature Medicine

P53 “Master Switch” Remains Top Target in Gene Signaling Network Controlling Cancer Suppression

“People have always been after the silver bullet against cancer and there are few things that are as relevant across cancer types as p53. Now the question is what is the best approach to harness it,” says senior author Joaquin Espinosa, PhD.

– University of Colorado Cancer Center

Genome Research

5 New Ways Health Care Providers Can Apply Individualized Medicine to Patient Care

Advancements in individualized medicine are offering health care providers new tools to quickly and accurately diagnose, treat, predict and, eventually, prevent disease.

– Mayo Clinic

Genetic Body/Brain Connection, DNA Damage Reversed, Whole Brain Map, and More in the Cell Biology News Source

The latest research and features in cell biology in the Cell Biology News Source

– Newswise

New Biomarker Predicts Metastatic Prostate Cancers

Many prostate cancers, which generally are diagnosed in older men, are "indolent," slow-growing tumors that aren't destined to be fatal. But some tumors are prone to becoming aggressive and spreading beyond the prostate, making them difficult to trea...

– Dana-Farber Cancer Institute

Clinical Cancer Research

DNA Damage Caused by Cancer Treatment Reversed by ZATT Protein

An international team led by scientists at the National Institutes of Health is the first to discover a new way that cells fix an important and dangerous type of DNA damage known as a DNA-protein cross-link (DPC). The researchers found that a protein...

– National Institute of Environmental Health Sciences (NIEHS)

Science; ZIAES102765; ZICES102488; ZIAES050111; R01GM105404

Some Breast Cancer Patients Don’t Need Radiation. Why Are They Still Getting It?

Recent clinical trials have shown that 90 percent of early stage breast cancer patients over age 70 do not benefit from radiation after breast-conserving surgery. And yet, use of radiation in this context has dropped only minimally. A new University ...

– Michigan Medicine - University of Michigan

Annals of Surgical Oncology, doi:10.1245/s10434-017-6013-1; P01CA163233

New Discovery about BRCA1

It's been 20 years since the BRCA1 gene was found to predispose women to breast cancer, and researchers at Yale have pinpointed what about the gene's mutation leads to cancer.

– Yale Cancer Center

Mystery of Breast Cancer Risk Gene Solved, 20 Years After Its Discovery

More than 20 years after scientists revealed that mutations in the BRCA1 gene predispose women to breast cancer, Yale scientists have pinpointed the molecular mechanism that allows those mutations to wreak their havoc.

– Yale Cancer Center

Want To Help A Loved One Coping With Cancer? Stay Positive

San Diego State University Professor Dr. Wayne Beach explains how positive, frequent communication by family members can truly help cancer patients.

Expert Available

– California State University (CSU) Chancellor's Office

Breast Cancer Treatment Has Evolved. Here’s Where We Are.

Targeted therapies are now available for approximately 85 percent of women diagnosed with breast cancer.

Expert Available

– University of California, Los Angeles (UCLA), Health Sciences

Scientists Find New RNA Class in Kidneys Is Linked to Hypertension

Researchers from the University of Toledo (Ohio) College of Medicine and Life Sciences have discovered more than 12,000 different types of noncoding RNA (circRNAs) in the kidney tissue of rats. This type of genetic material, previously thought to hav...

– American Physiological Society (APS)

Physiological Genomics

Researchers Identify Genetic Drivers of Most Common Form of Lymphoma

An international research effort led by Duke Cancer Institute scientists has been working to better understand the genetic underpinnings of the most prevalent form of this cancer -- diffuse large B cell lymphoma – and how those genes might play a r...

– Duke Health


Good-Guy Bacteria May Help Cancer Immunotherapies Do Their Job

Individuals with certain types of bacteria in their gut may be more likely to respond well to cancer immunotherapy, researchers at the Harold C. Simmons Comprehensive Cancer Center found in a study of patients with metastatic melanoma.

– UT Southwestern Medical Center

Neoplasia, Oct-2017

CRI Study Challenges Long-Standing Concept in Cancer Metabolism

Scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered that lactate provides a fuel for growing tumors, challenging a nearly century-old observation known as the Warburg effect.

– UT Southwestern Medical Center

Cell, Oct-2017

New Insights on the Addictions of Tumors

Stromal tissue may provide novel targets to disrupt tumor supply lines

– Sanford Burnham Prebys Medical Discovery Institute

Cell Metabolism, Oct 2017

Clearing the Air of Confusion About Mammography Guidelines

Published mammography guidelines differ on this and similar topics. With 1 in 8 U.S. women developing invasive breast cancer over the course of their lifetimes, knowing when to have this potentially lifesaving screening is critical.

– Beaumont Health

Cell Stress Response Sheds Light on Treating Inflammation-related Cancer, Aging

Stress – defined broadly – can have a profoundly deleterious effect on the human body. Even individual cells have their own way of dealing with environmental strains such as ultraviolet radiation from the sun or germs. One response to stress – ...

– Perelman School of Medicine at the University of Pennsylvania


Embargo expired on 04-Oct-2017 at 13:00 ET

Blood Test for HPV May Help Predict Risk in Cancer Patients

Preliminary findings presented at this year’s American Society for Radiation Oncology Annual Meeting suggest a genetic test for HPV16 in the blood could be useful to help assess risk for patients, and could help identify patients suitable for lower...

– University of North Carolina Health Care System

ASTRO Annual Meeting, Sept-2017

Delays for Melanoma Surgeries Linked to Insurance Type

Researchers report in JAMA Dermatology that surgical treatment delays – defined as surgery that occurred more than six weeks after diagnosis – were common. Medicaid patients were 36 percent more likely than private insurance patients to experienc...

– University of North Carolina Health Care System

JAMA Dermatology, Oct-2017

UWM-Developed App Helps Protect Patients’ Brains During Surgery

UW-Milwaukee students and a neuropsychologist jointly built a tablet app that helps brain surgeons identify tissue that would impair patient critical functions if removed.

– University of Wisconsin-Milwaukee

Moving From the Research Lab to Clinical Care: Precision Medicine Coming to Your Medical Provider’s Office

Individualized medicine — the concept of matching medical care precisely to each patient’s genes, lifestyle and environment is no longer just a theory. Experts in individualized medicine — also known as personalized or precision medicine — wi...

– Mayo Clinic

Individualizing Medicine 2017: Advancing Care Through Genomics

After Clinical Testing at UCLA, Immunotherapy Drug Approved by FDA to Treat Stomach Cancer

Pembrolizumab, a drug that has effectively extended the lives of countless people with many types of cancer, has now been approved by the U.S. Food & Drug Administration to treat people with metastatic gastric adenocarcinoma, the most common form of ...

– University of California, Los Angeles (UCLA), Health Sciences

New Technology Enables Shorter Radiation Treatment Time for Patients

Patients at UC San Diego Health in need of radiation therapy now have access to the next generation of radiation treatment technology. The new radiotherapy system significantly reduces treatment times with improved accuracy.

– University of California San Diego Health

Genetic Targets to Chemo-Resistant Breast Cancer Identified

Research led by Dr. Carlos Arteaga, Director of the Harold C. Simmons Comprehensive Cancer Center, has identified potential targets for treatment of triple negative breast cancer, the most aggressive form of breast cancer.

– UT Southwestern Medical Center

Journal of Cell Metabolism, Oct-2017


Cancer Research Institute to Honor Three Scientists for Their Outstanding Scientific Contributions to Cancer Immunology and Immunotherapy

The Cancer Research Institute will give awards for scientific achievements in immunology and tumor immunology and immunotherapy to three accomplished research scientists at its 31st Annual Awards Dinner on November 14, 2017, in New York City.

– Cancer Research Institute

Genentech CEO Bill Anderson and Philanthropist Bruce Ratner to Receive the Cancer Research Institute 2017 Oliver R. Grace Award for Distinguished Service in Advancing Cancer Research

Cancer Research Institute will recognize Genentech and Bruce Ratner for their contributions to medical research, patient care, or public education in the fields of cancer immunology and immunotherapy.

– Cancer Research Institute

Icahn School of Medicine at Mount Sinai Hosts 6th Annual SINAInnovations conference and Second Health Hackathon

The Icahn School of Medicine at Mount Sinai is preparing to host the 6th annual SINAInnovations conference, whose theme this year is “Cancer.”

– Mount Sinai Health System

6th Annual SINAInnovations, October 17-18

Markey's Blackburn Earns NIH New Innovator Award for Cancer Research

University of Kentucky Markey Cancer Center Researcher Jessica Blackburn has earned a prestigious National Institutes of Health's New Innovator Award, a grant totaling $1.5 million over five years to fund pediatric cancer research.

– University of Kentucky


Hackensack University Medical Center Foundation Receives Generous Donation from Celgene to Advance Multiple Myeloma Research at John Theurer Cancer Center

The Hackensack University Medical Center Foundation has received a substantial donation from Celgene Corporation to advance multiple myeloma research and transformational medicine that improve patient outcomes at Hackensack Meridian Health - John The...

– Hackensack Meridian Health

Richard Price of UVA Receives Inaugural Andrew J. Lockhart Prize

The Focused Ultrasound Foundation announced that Richard Price, PhD, professor of biomedical engineering, radiology and radiation oncology at the University of Virginia, has been selected as the inaugural recipient of the $75,000 Andrew J. Lockhart M...

– Focused Ultrasound Foundation

Cancer Immunologist Andrea Schietinger of Sloan Kettering Institute Honored with Prestigious NIH Director’s New Innovator Award

Cancer immunologist Andrea Schietinger, PhD, of the Sloan Kettering Institute (SKI) at Memorial Sloan Kettering (MSK) has been honored with the prestigious National Institutes of Health (NIH) Director’s New Innovator Award.

– Memorial Sloan Kettering Cancer Center

NIH Grant Number: DP2-CA-225212

NIH Selects Wistar Scientist Kavitha Sarma, Ph.D., for New Innovator Award

The Wistar Institute, an international leader in biomedical research in the fields of cancer, immunology and infectious diseases, announces Kavitha Sarma, Ph.D., assistant professor in Wistar’s Gene Expression and Regulation Program, has been award...

– Wistar Institute

ProMedica Toledo Hospital First in Ohio to Acquire Synaptive’s Advanced Neurosurgery System

ProMedica Toledo Hospital is the first in Ohio to acquire BrightMatter™ technology, an innovative solution that combines advanced imaging, planning, navigation and robotics for complex brain tumor and spinal surgery.

– ProMedica

Surge of New Cancer Center Leadership Marks 2017 AACI/CCAF Annual Meeting

The Association of American Cancer Institutes will host about two dozen new cancer center directors at its annual meeting in Washington, DC, October 15 - 17.

– Association of American Cancer Institutes (AACI)

2017 AACI/CCAF Annual Meeting

$2.4M Grant Aids Exploration of Social Media to Reduce Indoor Tanning Behavior

A $2.4 million grant from the National Cancer Institute awarded to Rutgers Cancer Institute of New Jersey behavioral scientist will support the development and testing of a novel behavioral intervention delivered through the social media site Faceboo...

– Rutgers Cancer Institute of New Jersey


Higher Education Events

Third Annual Motorcycle Ride to Raise Money and Awareness for Breast Cancer

The Turquoise Trail Harley Owners’ Group and Thunderbird Harley Davidson will welcome more than 100 riders for the third annual “Pink Your Ride — Motorcyclists Increasing Awareness (MIA)” motorcycle ride. The ride raises awareness for breast ...

– University of New Mexico Comprehensive Cancer Center

Embargo expired on 09-Oct-2017 at 05:00 ET

Expert Pitch

Yale Expert Wins Prestigious 2017 Warren Alpert Prize

– Yale Cancer Center

Daniel P. Petrylak, MD, on Urothelial Carcinoma: Results of the RANGE Trial

– Yale Cancer Center

How Close are Researchers to a “Real Shot Against Breast Cancer”?

– BriaCell Therapeutics Corp





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