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Newswise Special Wire
Tuesday, October 31, 2017

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Newswise Cancer Research Wire for 31-Oct-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

How an Interest in Bipolar Disorder Drugs Led to a Better Understanding of Leukemia

A research project that began 20 years ago with an interest in how lithium treats mood disorders has yielded insights into the progression of blood cancers such as leukemia. The research, which centers on a protein called GSK-3, will be published in ...

– American Society for Biochemistry and Molecular Biology (ASBMB)

Journal of Biological Chemistry, Nov-2017

No-Shave November Will Continue Supporting Fight Colorectal Cancer

No-Shave November is a movement encouraging men and women to discontinue shaving and donate the savings instead during the month of November. No-Shave November, a nonprofit, is splitting the funds raised in 2017 between three charities, one being Fig...

– Fight Colorectal Cancer

Gene Expression Study Reveals “Hidden” Variability in How Cancer Cells Respond to Drugs

Drug exposure can cause significant changes in gene expression without affecting growth or survival in some cell lines, highlighting strategies to better evaluate drug effectiveness.

– Harvard Medical School

Nature Communications

Embargo expired on 30-Oct-2017 at 06:00 ET

Minorities Less Likely to Have Breast Reconstruction, But Not for the Reason Many Think

Minority women are far less likely to undergo breast reconstruction than white women, even if they live in the same area and have similar insurance.

– Perelman School of Medicine at the University of Pennsylvania

The American Journal of Surgery

Umbilical Cord Blood Improves Motor Skills in Some Children With Cerebral Palsy

An infusion of cells from a child’s own umbilical cord blood appears to improve brain connectivity and motor function in children with spastic cerebral palsy, according to a randomized clinical trial published this week by Stem Cells Translational ...

– Duke Health

Stem Cells Translational Medicine

Rousing Masses to Fight Cancer with Open Source Machine Learning

Sharing is caring in the fight against cancer with this open source software project to predict cancer drug effectiveness. Georgia Tech researchers have kicked it off with a program they tested to be about 85% effective in making predictions in indiv...

– Georgia Institute of Technology

PLOS One; Rising Tide Foundation

Scientists Discover Surprising Immune Cell Activity That May Be Limiting Immunotherapy

Researchers have uncovered a surprising process within a key immune cell that may help explain the limitations of immunotherapy as a cancer treatment.

– Michigan Medicine - University of Michigan

Nature Immunology; CA156685; CA171306; CA190176; CA193136; CA211016; 5P30CA46592; CA217540; CA123088; CA099985

Fred Hutch Tip Sheet: New Take on Prostate Cancer Screening; Fruit Fly Obesity; Nanoparticles for Gene Therapy; TCRs for Relapsing Leukemia and More

The October tip sheet from Fred Hutchinson Cancer Research Center includes story ideas about a new take on prostate cancer screening; fruit fly obesity; nanoparticles for gene therapy; TCRs for relapsing leukemia and more. Each tip links to more deta...

– Fred Hutchinson Cancer Research Center

Zika Transmission, Overcoming Resistance to Immunotherapy, ASCB's E.E. Just Award, Proteins of the Ear, and More in the Cell Biology News Source

The latest research and features in cell biology in the Cell Biology News Source

– Newswise

Overcoming Resistance to Immunotherapy

For some cancer patients, the road to remission and healing can have its share of speed bumps. That’s particularly true of patients with non-small cell lung cancer (NSCLC) who develop a secondary, or acquired, resistance to immunotherapy, which ini...

Expert Available

– Yale Cancer Center

Some Factors That May Skew Your PSA Test Results

The PSA test does not specifically check for prostate cancer itself, but rather for the presence of a molecule in the blood naturally made by the prostate.Here are common factors to be aware of that could change your PSA test results.

Expert Available

– University of California, Los Angeles (UCLA), Health Sciences

Details Uncovered in Development of Immune Cell Implicated in Cancer, Autoimmune Diseases

Scientists understand new details about the development of Th17, a type of immune cell that is believed to play a complex role in cancer, and is also implicated in autoimmune diseases.

– University of North Carolina Health Care System

Nature, Oct-2017

Mutation in Fallopian Tube Lesions May Help Catch Ovarian Cancer Years Earlier

Screening for tumor cells in the fallopian tubes of women at high-risk for ovarian cancer may help detect the cancer years before it develops further, suggests a new study co-led by researchers at Penn Medicine and published online this week in Natur...

– Perelman School of Medicine at the University of Pennsylvania

Nature Communications

Regional Anesthesia Linked to Improved Outcomes for Breast Cancer Patients

According to research published in Regional Anesthesia and Pain Medicine, the use of regional anesthesia is associated with lower levels of inflammation and a better immune response in breast cancer surgery patients.

– American Society of Regional Anesthesia and Pain Medicine (ASRA)

Regional Anesthesia and Pain Medicine

The Brain Region for Balance, Movement Also Involved in Processing Traumatic Memories

The cerebellum is activated in patients using the neuro-emotional technique (NET) to alleviate stress from traumatic cancer-related memories.

– Thomas Jefferson University

Journal of Cancer Survivorship

Timing Could Matter to How Responsive Cancer Cells Are to Treatment, Study Suggests

In a new study published in Cell Systems, UNC Lineberger's Jeremy Purvis, PhD, and colleagues report that the timing of when DNA damage occurs within these different checkpoints matters to a cell’s fate.

– University of North Carolina Health Care System

Cell Systems, Oct-2017

Embargo expired on 25-Oct-2017 at 12:00 ET

New Study: ‘Double Decker’ Antibody Technology Fights Cancer

Scientists from the Florida campus of The Scripps Research Institute have created a new class of antibody-drug conjugates for cancer therapy.

– Scripps Research Institute

Nature Communications

Fred Hutch Researchers Engineer Complex TCR Immunotherapy That May Target Relapsing Leukemia

Researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a novel way to genetically engineer T cells that may be effective for treating and preventing leukemia relapse. The findings provide the basis for l...

– Fred Hutchinson Cancer Research Center

Blood, Oct 2017

Insights From a Rare Genetic Disease May Help Treat Multiple Myeloma

A new class of drugs for blood cancers such as leukemia and multiple myeloma is showing promise. But it is hobbled by a problem that also plagues other cancer drugs: targeted cells can develop resistance. Now scientists, reporting in ACS Central Scie...

– American Chemical Society (ACS)

ACS Central Science

Cells’ Mechanical Memory Could Hold Clues to Cancer Metastasis

In the body, cells move around to form organs during development; to heal wounds; and when they metastasize from cancerous tumors. A mechanical engineer at Washington University in St. Louis found that cells remember the properties they had in their ...

– Washington University in St. Louis


Sexual Function Concerns Not Always Reflected in Prostate Cancer Treatment Choices

A study led by UNC Lineberger Comprehensive Cancer Center researchers found that preference for preserving sexual function was not strongly reflected in the treatment choices of men with low-risk prostate cancer.

– University of North Carolina Health Care System

JNCI, Oct-2017

How Might High Intensity Exercise Training (HIIT) Prevent Colon Cancer?

Latest Research Highlights from ACSM

– American College of Sports Medicine (ACSM)

Medicine & Science in Sports & Exercise: September 2017 - Volume 49 - Issue 9 - p 1805–1816

Vanderbilt-Ingram Cancer Center Patients Treated with New FDA-Approved CAR T Therapy

Vanderbilt-Ingram Cancer Center (VICC) has been selected as one of the few authorized treatment centers in the United States approved to administer the first FDA- approved chimeric antigen receptor T cell (CAR T) therapy for treatment of adult patien...

– Vanderbilt University Medical Center

How Can I Decrease My Breast Cancer Risk?

Breast cancer is the most common cancer among American women (except for skin cancers). One in eight women in the United States will develop invasive breast cancer during their lifetime with an estimated 252,710 new cases of invasive breast cancer in...

– Valley Health System

Tarloxitinib Puts Tumor-Seeking Tail on Anti-EGFR Drug to Precisely Target Lung Cancer

University of Colorado Cancer Center study being presented October 28 at the AACR-NCI-EORTC International Conference on Molecular Targets: By pairing an anti-EGFR drug with a “tail” that only activates the drug when it is very near tumor cells, t...

– University of Colorado Cancer Center

AACR-NCI-EORTC Molecular Targets


Rush Honored for Providing Highest-Quality Lung Cancer Care in North America

Rush University Medical Center’s lung cancer care team is one of two programs that provide the highest-quality lung cancer care in North America, according to the International Association for the Study of Lung Cancer (IASLC), which chose Rush as o...

– Rush University Medical Center

Historic Partnership Grant Advances Immunotherapy Research of Mary Markiewicz, Ph.D., at the University of Kansas Cancer Center

.Mary Markiewicz, Ph.D., assistant professor at the University of Kansas Medical Center in the Department of Microbiology, Molecular Genetics and Immunology and a researcher with KU Cancer Center, will receive a grant, made possible by a unique partn...

– University of Kansas Cancer Center

Mayo Clinic to Offer CAR T-Cell Therapy for Relapsed Non-Hodgkin Lymphoma

Mayo Clinic announced today that its Rochester campus is one of 16 cancer centers nationally selected to provide chimeric antigen receptor T-cell therapy (CAR T-cell therapy) for adults with B-cell non-Hodgkin lymphoma who have not responded to, or h...

– Mayo Clinic

Six World-Class Research Teams to Investigate Overcoming Therapeutic Resistance in High Fatality Cancers

The Canadian Institutes of Health Research (CIHR), the International Development Research Centre (IDRC), the Azrieli Foundation and the Israel Science Foundation (ISF) are pleased to announce the recipients of the Joint Canada-Israel Health Research ...

– Canadian Institutes of Health Research (CIHR)

Tourassi Named Top Scientist at ORNL’s Annual Awards Night

Georgia Tourassi of Oak Ridge National Laboratory’s Computing and Computational Sciences Directorate has received the ORNL Director’s Award for Outstanding Individual Accomplishment in Science and Technology.

– Oak Ridge National Laboratory

Public-Private Consortium Aims to Cut Preclinical Cancer Drug Discovery from Six Years to Just One

Description: Lawrence Livermore National Laboratory, Frederick National Laboratory for Cancer Research, GSK, and University of California San Francisco will combine vast data stores, supercomputing, and scientific expertise to reinvent the discovery ...

– Lawrence Livermore National Laboratory

Embargo expired on 27-Oct-2017 at 11:30 ET

Dream Team Aims to Intercept Pancreatic Cancer Before It Flourishes

Deeply entrenched and mature by the time it’s found, pancreatic cancer is one of the hardest to defeat. A Dream Team assembled by Stand Up to Cancer and led by an investigator at The University of Texas MD Anderson Cancer Center will test new ways...

– University of Texas M. D. Anderson Cancer Center

UC San Diego Health Researchers Help Launch Second Pancreas Cancer “Dream Team”

Scientists and physicians at Moores Cancer Center at UC San Diego Health, in partnership with colleagues at MD Anderson Cancer Center in Texas, Johns Hopkins University in Maryland and elsewhere, have been awarded a $7 million grant over four years b...

– University of California San Diego Health

AACI, ACS, and CDC Recognize Pediatric Practices for High HPV Vaccination Rates

The Association of American Cancer Institutes, the American Cancer Society, Inc., and the Centers for Disease Control and Prevention’s National Center For Immunization and Respiratory Diseases announced 10 award winners as part of its HPV Vaccine I...

– Association of American Cancer Institutes (AACI)

National Comprehensive Cancer Network Hits One Million Registered Users Accessing the NCCN Guidelines® and Related Content

Growing NCCN registration numbers help ensure that new cancer treatment developments reach patients worldwide.

– National Comprehensive Cancer Network® (NCCN®)

Gift From Eden and Steven Romick to Support Cancer Research

A significant gift from philanthropists Eden ’90 and Steven Romick ’85 to Northwestern University has established a collaborative international partnership between Northwestern’s International Institute for Nanotechnology and the Weizmann Insti...

– Northwestern University

First Ever Clinical Trial Evaluating Keytruda in Combination with Focused Ultrasound for Metastatic Breast Cancer Begins at University of Virginia

For the first time, non-invasive focused ultrasound therapy is being used to ablate (or destroy) a portion of the primary tumor or metastatic tumors in conjunction with the cancer immunotherapy drug Keytruda.

– Focused Ultrasound Foundation

Expert Pitch

Enlarged Prostate: Northwestern Medicine Offers New Minimally Invasive Breakthrough Treatment

– Northwestern Medicine

Prostate Cancer: What You Need to Know

– University of Alabama at Birmingham





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