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Newswise Special Wire
Tuesday, January 2, 2018

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Newswise Cancer Research Wire for 02-Jan-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Immune Cells Play Key Role in Early Breast Cancer Metastasis Even Before a Tumor Develops

Mount Sinai researchers have discovered that normal immune cells called macrophages, which reside in healthy breast tissue surrounding milk ducts, play a major role in helping early breast cancer cells leave the breast for other parts of the body, po...

– Mount Sinai Health System

Nature Communications, Jan-2018

Embargo expired on 02-Jan-2018 at 05:00 ET

Quitting Cigarettes: One of the Toughest New Year’s Resolutions

Deciding to stop smoking is one of the most common, beneficial and difficult New Year’s resolutions. Smoking reminders are abundant, nicotine withdrawal is difficult and the resolution process itself is flawed.

Expert Available

– University of Chicago Medical Center

Opioid Prescribing to the Disabled, Gene Therapy for Long-term HIV Protection, Improving Patient Access, and More in the Public Health News Source

The latest research, experts and features in Public Health in the Public Health News Source

– Newswise

Carfilzomib Can Lead to Cardiovascular Toxicity in Multiple Myeloma Patients

The proteasome inhibitor carfilzomib has taken on an increasing role in the treatment of multiple myeloma, but new research from the Abramson Cancer Center of the University of Pennsylvania shows the therapy comes with the risk of cardiovascular pro...

– Perelman School of Medicine at the University of Pennsylvania

JAMA Oncology; T32-GM075766

Breaking Up (Protein Complexes) Is Hard to Do, but New UW Study Shows How

A new study by University of Wisconsin-Madison researchers identified the structural basis for how tightly bound protein complexes are broken apart to become inactivated.

– University of Wisconsin-Madison

Nature Communications; R01 GM096060-01

Embargo expired on 22-Dec-2017 at 05:00 ET

UK Study Finds Biomarker Targets to Make Drugs More Effective in Fighting Cancer

A new study published in Nature Communications and led by University of Kentucky Markey Cancer Center researcher Qing-Bai She identifies biomarker targets that may make existing drugs more effective in fighting certain cancers.

– University of Kentucky

Nature Communications

First Stereotactic Radiation Therapy System Designed to Treat Early Stage Breast Cancer Receives FDA Clearance

The GammaPod ™ – a first-of-its kind stereotactic radiotherapy system to treat early stage breast cancer – has received 510(k) clearance from the U.S. Food and Drug Administration (FDA), paving the way for the manufacturer to bring the system t...

– University of Maryland Medical Center/School of Medicine

Environmental Stressors, CRISPR Treatment for Hearing Loss, Mitochondria and Cocaine Addiction, and More in the Cell Biology News Source

The latest research and features in cell biology in the Cell Biology News Source

– Newswise

A Fluorescence-Based High-Throughput Assay for the Identification of Anticancer Reagents Targeting Fructose-1,6-Bisphosphate Aldolase

An original research report by Eun Jeong Cho et al. (University of Texas at Austin) in the January 2018 Issue of SLAS Discovery presents a newly designed biochemical assay that is rapid, sensitive, inexpensive, and high-throughput screening (HTS)-fri...

– SLAS (Society for Laboratory Automation and Screening)

SLAS Discovery

Lawrence Livermore National Laboratory Biomedical Technology Licensed to Michigan Company for Use in Cancer Treatments

A Lawrence Livermore National Laboratory biomedical technology that can deliver vaccines and drugs inside the human body has been licensed for use in cancer treatments to a Michigan company.

– Lawrence Livermore National Laboratory

Roswell Park Research Identifies Cells That May Be Responsible for Prostate Cancer Recurrence

A team from Roswell Park Cancer Institute has discovered a unique population of normal stem cells that may enable prostate cancer relapse. These findings may point the way toward strategies for treating or preventing prostate cancer recurrence.

– Roswell Park Cancer Institute

Stem Cell Reports; R01CA155693; P30CA016056

Education Beyond Borders

Harvard Medical School will offer online education to doctors-in-the-making and practicing clinicians affiliated with a pediatric cancer hospital in Egypt, the 57357 Children’s Cancer Hospital in Cairo.

– Harvard Medical School

More Tumor Mutations Equals Higher Success Rate With Cancer Immunotherapy Drugs

The "mutational burden," or the number of mutations present in a tumor's DNA, is a good predictor of whether that cancer type will respond to a class of cancer immunotherapy drugs known as checkpoint inhibitors, a new study led by Johns Hopkins Kimme...

– Johns Hopkins Medicine

New England Journal of Medicine

Embargo expired on 20-Dec-2017 at 17:00 ET

High Out-of-Pocket Costs May Place Oral Cancer Medications Out of Reach

Sticker shock may be leading many insured Americans with cancer to forego treatment with a wide range of oral cancer drugs, suggests a study published online this week in the Journal of Clinical Oncology. Led by researchers at the Perelman School of ...

– Perelman School of Medicine at the University of Pennsylvania

Embargo expired on 20-Dec-2017 at 16:00 ET

Study Finds New Way to Clean Up Radioactive Sites, Protect Radiotherapy Patients, Astronauts

A new discovery by scientists could aid efforts to clean up radioactive waste sites, and could also help protect military personnel, cancer patients, and astronauts.

– Uniformed Services University of the Health Sciences (USU)

(Defense Threat Reduction Agency, grant HDTRA-18774-M)

Embargo expired on 20-Dec-2017 at 14:00 ET

Emergency Department Cancer Diagnoses: An Underreported Problem

New study, published in the American Journal of Surgery, highlights the prevalence of ED cancer diagnoses; calls for new screening methods.

– Montefiore Health System

American Journal of Surgery

Embargo expired on 20-Dec-2017 at 00:00 ET

Removal of Drug Coverage Caps Associated with Improved Medication Persistence

Value in Health, the official journal of ISPOR (the professional society for health economics and outcomes research), announced today the publication of a research report suggesting that the removal of drug coverage caps may lead to improved medicati...

– ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health, Dec-2017

Harnessing Sperm to Treat Gynecological Diseases

Delivering drugs specifically to cancer cells is one approach researchers are taking to minimize treatment side effects. Stem cells, bacteria and other carriers have been tested as tiny delivery vehicles. Now a new potential drug carrier to treat gyn...

– American Chemical Society (ACS)

ACS Nano

Can You Burn Calories While Sitting at a Desk?

A new study suggests that continuous movement while sitting may increase metabolic rate more than standing at a desk.

– University of Illinois at Chicago


Emerging Drug Could Help Treat a Common Liver Disease

Treating a liver disease called NASH (non-alcoholic steatohepatitis) is difficult. Now scientists believe they have found a pharmacologic approach that may inhibit NASH, and thus stop deadly conditions that result from NASH.

– Stony Brook University

Cellular and Molecular Gastroenterology and Hepatology

New Class of Anti-Cancer Drug Effective Against Kidney Cancer

A study published in the Journal of Clinical Oncology reports initial findings with a novel drug belonging to a new class of medicines called HIF-2a inhibitors that show promise in treating metastatic kidney cancer.

– UT Southwestern Medical Center

Journal of Clinical Oncology

Study: Medications Alone Don’t Help Smokers Quit

Pharmaceutical interventions are routinely prescribed to help people quit smoking. However, a new study by University of California San Diego School of Medicine researchers suggests that, despite promising results in clinical trials, smoking cessatio...

– University of California San Diego Health

Journal of the National Cancer Institute

Quit Smoking in the New Year with Help From Rutgers

Are you trying to quit smoking in the New Year? According to The Tobacco Dependence Program at Rutgers University, most people who smoke regret having started and want to stop. However, quitting can be hard to do. Rutgers outlines the top ten things ...

– Rutgers Robert Wood Johnson Medical School

Metabolic Vulnerability of Certain Breast Cancers, Radiosurgery for Brain Cancer, Measuring Radiation Therapy, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

– Newswise

Ludwig Researchers Uncover Mechanism Behind a Metabolic Vulnerability of Certain Breast Cancers

Many cancer cells are relatively sensitive to the deprivation of an essential amino acid known as methionine. Now, a Ludwig Cancer Research study published in the journal Science Signaling and led by Alex Toker, an investigator in the Ludwig Center a...

– Ludwig Cancer Research

Science Signaling, Dec-2017

Electric Scalp Device Prolongs Survival in Deadly Brain Cancer

A device attached to a patient’s scalp that delivers a continuous dose of low-intensity electric fields improves survival and slows the growth of a deadly brain tumor, according to a new clinical trial led by a Northwestern Medicine scientist and p...

– Northwestern University


Researchers Find Possible Markers for Earlier Diagnosis of Aggressive Form of Tongue Cancer

Squamous cell carcinoma of the tongue, also known as oral tongue cancer, is an aggressive form of cancer that generally affects older people. Patients with the disease often find it difficult to eat, swallow food, or speak. Reasons for its generally ...

– Case Western Reserve University

Oncotarget; Steris Foundation; VeloSano3; Doris Duke Clinical Research Mentorship Award; NIH R01DE21544 ; NIH R01DE024228


$1M Grant Supports Rutgers Cancer Institute of New Jersey Researcher on International Prostate Cancer Study

A $1 million grant from Gateway for Cancer Research will help Rutgers Cancer Institute of New Jersey Urologic Oncology Chief Isaac Yi Kim, MD, PhD, MBA evaluate the impact of surgically removing the prostate in men with metastatic prostate cancer in ...

– Rutgers Cancer Institute of New Jersey

New Cancer Treatment Technology Coming to Utah

A new cancer treatment technology is one step closer to Salt Lake City. Today Huntsman Cancer Institute (HCI) at the University of Utah (U of U) announced a plan to add a proton therapy center to its Cancer Hospital. Huntsman Cancer Foundation, HCI a...

– Huntsman Cancer Institute at the University of Utah

Rutgers Cancer Institute of New Jersey and RWJBarnabas Health Enhance Clinical Research Focus with Arrival of Internationally Recognized Clinical Trials Expert

Further enhancing a commitment to cutting-edge clinical research efforts, Rutgers Cancer Institute of New Jersey and RWJBarnabas Health are welcoming Howard S. Hochster, MD, an internationally recognized leader in the development of cancer clinical t...

– Rutgers Cancer Institute of New Jersey

Translational Research Fellowship Established; Prostate Cancer Pioneer Lauded

The new COL (Ret.) David G. McLeod Prostate Cancer Translational Research Fellowship was awarded to Dr. Prachi Mishra, Dec. 7 at the Uniformed Services University of the Health Sciences (USU), in a ceremony in front of Department of Defense and indus...

– Uniformed Services University of the Health Sciences (USU)

Expert Pitch

Quitting cigarettes: One of the toughest new year’s resolutions; UChicago Medicine expert offers tips on getting past “false hope syndrome”

– University of Chicago Medical Center

Seattle Cancer Care Alliance Genetic Counselor Available for Interview

– Seattle Cancer Care Alliance





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