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Newswise Special Wire
Tuesday, January 23, 2018

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Newswise Cancer Research Wire for 23-Jan-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Using ‘LOHGIC’ to Assess Inherited Cancer Mutations

Investigators at Rutgers Cancer Institute of New Jersey have developed a statistical method to identify patients with potential inherited, germline alterations in tumor suppressor genes while estimating gene loss in cancer cells through targeted geno...

– Rutgers Cancer Institute of New Jersey

JCO Precision Oncology, Jan-2018

Cryo-EM Reveals Critical Protein-Modifying Complex and Potential Drug Target

Scientists have revealed the atomic-level structure of a molecular complex responsible for modifying proteins, possibly paving the way for the development of new medications for cancer and a host of other diseases.

– Van Andel Research Institute

Embargo expired on 22-Jan-2018 at 11:00 ET

Let’s Talk About End-of-Life Care

A new study in JNCCN finds majority of people with cancer would like their physicians to ask them where they would prefer to receive end-of-life care.

– National Comprehensive Cancer Network® (NCCN®)

Journal of the National Comprehensive Cancer Network

Microbiome Predicts Blood Infections in Pediatric Cancer Patients

Patients who developed bloodstream infections had significantly reduced microbiome diversity than patients who remained free of infection.

– University of Colorado Cancer Center

PLoS One

Enzyme Inhibitor Combined with Chemotherapy Delays Glioblastoma Growth

In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, temozolomide.

– University of Alabama at Birmingham

JCI Insight; CA200085; NS096531; CA1515122; CA151129

‘Hijacker’ Drives Cancer in Some Patients with High-Risk Neuroblastoma

Researchers in Memphis and Boston have collaborated to show c-MYC is an oncogene that drives neuroblastoma in some high-risk patients; the findings help set the stage for much-needed precision medicines

– St. Jude Children's Research Hospital

Cancer Discovery

Study to Determine Which Stool Test Is Best for Colorectal Cancer Detection

FIT tests, or fecal immunochemical tests, are noninvasive and simple to collect in the privacy of one's own home, with no dietary or medical restrictions. But just how accurate are these new FIT tests? That’s what faculty at Texas Tech University H...

– Texas Tech University Health Sciences Center El Paso

Precision Medicine: Fighting Breast Cancer on the Molecular Level

When most of us think of breast cancer, we envision a malignant lump. It might be large. It might be small. But it’s all the same. It’s cancer.

– Magee-Womens Research Institute

Treatment-Related Mortality of Surgery vs. Targeted Radiation in Early Lung Cancer Patients

Among patients older than 80 years, 3.9 percent receiving surgery passed away within the 30-day post-treatment window, compared with 0.9 percent of patients receiving focused radiation.

– University of Colorado Cancer Center

Journal of Clinical Oncology

Cells Lacking Nuclei Struggle to Move in 3-D Environments

A study led by UNC Lineberger Comprehensive Cancer Center and published in the Journal of Cell Biology examined the role of the physical structure of the nucleus in cell movement through different surfaces.

– University of North Carolina Health Care System

Journal of Cell Biology

Can Mice Really Mirror Humans When It Comes to Cancer?

A new Michigan State University study is helping to answer a pressing question among scientists of just how close mice are to people when it comes to researching cancer.

– Michigan State University

PLOS Genetics

Embargo expired on 18-Jan-2018 at 14:00 ET

More Evidence of Link Between Severe Gum Disease and Cancer Risk

Data collected during a long-term health study provides additional evidence for a link between increased risk of cancer in individuals with advanced gum disease, according to a new collaborative study led by researchers at the Johns Hopkins Bloomberg...

– Johns Hopkins Medicine

Journal of the National Cancer Institute; R01HHSN268201700001I, HHSN268201700003I, HHSN268201700005I, HHSN268201700004I, HHSN268201700002I; R01 CA166150, U01 CA164975, P30 CA006973...

Single Blood Test Screens for Eight Cancer Types

Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.

– Johns Hopkins Medicine

Science; P50-CA62924, P50-CA102701, CA06973, GM-07309, U01CA152753

Two New Breast Cancer Genes Emerge from Lynch Syndrome Gene Study

Columbia University researchers have identified two new breast cancer genes that also cause Lynch syndrome.

– Columbia University Medical Center

Genetics in Medicine, January 18, 2018

Researchers Discover New Enzymes Central to Cell Function

Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins function. But new research featured in Molecular C...

– Case Western Reserve University

Molecular Cell; NIH

Finally, Data About Alternative Medicine and Cancer

According to Altmetric, which tracks the distribution and discussion of research papers online, a July article by several Yale physicians is the most-discussed paper ever published in the Journal of the National Cancer Institute (JNCI). The title of ...

– Yale Cancer Center

Journal of the National Cancer Institute

UCLA Study Describes Structure of Tumor Herpes Virus Associated with Kaposi's Sarcoma

UCLA team shows in the laboratory that an inhibitor can be developed to break down the herpes virus.

– University of California, Los Angeles (UCLA), Health Sciences

Nature, Jan. 17, 2018; National Institutes of Health (NIH) (DE025567, GM071940, AI094386, CA091791 and CA177322)

New Registry Launched to Track and Improve the Quality of Cancer Care Delivered in the U.S.

A registry that tracks the quality of medical care provided to patients receiving cancer treatment launched this month as part of a collaboration between the American Society of Clinical Oncology (ASCO) and the American Society for Radiation Oncology...

– American Society for Radiation Oncology (ASTRO)

Bioengineered Soft Microfibers Improve T-Cell Production

Columbia biomedical engineers design a new, biomaterials-based system that takes a soft approach to improving cell manufacturing and may bring new hope to cancer patients for T-cell therapy.

– Columbia University School of Engineering and Applied Science

Advanced Biosystems Jan18 2017

Embargo expired on 17-Jan-2018 at 18:30 ET

Pacientes Que Tienen Precursor De Cáncer Sanguíneo Corren Riesgo De Desarrollar Cáncer Incluso Después De 30 años

Los pacientes con gammapatía monoclonal de significado incierto corren más riesgo de avanzar hacia mieloma múltiple u otro cáncer afín, incluso después de 30 años de estabilidad.

– Mayo Clinic

New England Journal of Medicine

Embargo expired on 17-Jan-2018 at 17:00 ET

DIPG Tumor Patterns Offer New Insight on Survival

A small subset of patients with histone mutations may have better outcomes than others, suggests new research from Michigan Medicine’s Pediatric Brain Tumor Research Initiative.

– Michigan Medicine - University of Michigan

Acta Neuropathologica

Researchers Identify New Way to Unmask Melanoma Cells to the Immune System

A research team at the Duke Cancer Institute has found a new way to keep the immune system engaged, and is planning to test the approach in a phase 1 clinical trial.

– Duke Health

Immunity; 1K08CA191063-01A1


NYU's Dr. Brian Schmidt and Columbia's Dr. Nigel Bunnett Awarded NIH Grant to Investigate Proteases and Pain Signaling Related to Oral Cancer

The National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health (NIH), has awarded Brian Schmidt, DDS, MD, PhD, of the Bluestone Center for Clinical Research at New York University College of Dentistry (N...

– New York University


Mangurian Foundation Donates $20 Million to Mayo Clinic to Name New Medical Building

Mayo Clinic’s Florida campus has received a $20 million gift from The Harry T. Mangurian Jr. Foundation in Fort Lauderdale, Florida, to support expansion projects and a new medical building for cancer and neurologic care.

– Mayo Clinic

Rutgers Cancer Institute of New Jersey Recognized as a Center of Excellence for Work on Myelodysplastic Syndromes

Rutgers Cancer Institute of New Jersey is now recognized as a Center of Excellence by the Myelodysplastic Syndromes (MDS) Foundation in the research, diagnosis and treatment of MDS disorders.

– Rutgers Cancer Institute of New Jersey

Yale Cancer Center Receives $1 Million Grant to Address Cancer Disparities

Yale Cancer Center (YCC) has been awarded a $1 million grant by the Bristol-Myers Squibb Foundation (BSMF) to address health care disparities in cancer care and support.

– Yale Cancer Center

NJ Residents Gain Greater Access to Gynecologic Oncology Expertise in Monmouth, Ocean and Middlesex Counties with Verda Hicks, M.D. Joining Jersey Shore University Medical Center

Verda J. Hicks, M.D., FACS, FACOG has joined Hackensack Meridian Health as chief of Gynecologic Oncology at Jersey Shore University Medical Center. She also is medical director of Gynecologic Oncology for Hackensack Meridian Health Cancer Care in Mon...

– Hackensack Meridian Health

Harrington Discovery Institute at University Hospitals Announces 2018 Grant Funding to 10 Physician-Scientists

Announcement of the 2018 Harrington Scholar-Innovator Award recipients by the Harrington Discovery Institute at University Hospitals in Cleveland, Ohio.

– University Hospitals Cleveland Medical Center

National Academy of Sciences Awards Kovalenko Medal to Immunotherapy Pioneer Allison

Cancer immunotherapy innovator Jim Allison, Ph.D., chair of Immunology at The University of Texas MD Anderson Cancer Center, will receive the 2018 Jessie Stevenson Kovalenko Medal for outstanding research in medical sciences, the National Academy of ...

– University of Texas M. D. Anderson Cancer Center

NIH Invests in Collaborative Research to Understand Mechanisms Controlling Cell Division

A three-year, $675,000 grant from the National Institutes of Health (NIH) to understand cell-size control in the unicellular green alga Chlamydomonas reinhardtii.

– Donald Danforth Plant Science Center


Higher Education Events

Legislators to Take Shots at Cancer

New Mexico state legislators will divide along house lines in the end-of-session hotly contested basketball game Feb. 5. UNM Football Head Coach Bob Davie will coach the Senate "Lobos" and NMSU Football Head Coach Doug Martin will coach the House of ...

– University of New Mexico Comprehensive Cancer Center

Expert Pitch

January is Cervical Health Awareness Month: GW Experts Available

– George Washington University





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