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Newswise Special Wire
Tuesday, February 6, 2018

Public edition |

Newswise Cancer Research Wire for 06-Feb-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Researchers One Step Closer to Treating Organ Fibrosis

A novel antibody-based therapy that blocks the excessive formation of collagen clusters is safe and effective in multiple animal models of fibrotic disease

– Thomas Jefferson University

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

An Cyanine Dye Acid Test that Won't Drown in Water

Near-infrared cyanine dyes are go-to tools for studying the inner workings of cells and investigating the biochemistry of disease, including cancer. But even though they have low toxicity and plenty of applications, these fluorescent dyes have a weak...

– Michigan Technological University

Chemical Communications, Jan-2018 ; National Institute of General Medical Sciences of the National Institutes of Health R15GM114751; National Science Foundation 1048655

Engineers Use Natural Protein as Nanoshuttle for Anti-Cancer Vaccines

Clinical application of cancer fighting nanovaccines has been hampered by complications in large-scale manufacturing, quality control, and safety. Biomedical engineers developed nanovaccines that bind to the albumin protein naturally present in the b...

– National Institute of Biomedical Imaging and Bioengineering

Nat Commun, Dec-2017

Loved One’s Death Could Spur Aggressive Measures Against Breast Cancer

A woman’s memories of a loved one’s experience with cancer could play a significant role in how she approaches breast cancer prevention in her own life, a new study has found.

– Ohio State University

Journal of Health Psychology

Mitochondrial DNA and Its Role in Cancer Metastasis

Researchers at The University of Kansas Cancer Center have found that mitochondrial DNA may contain information that could help determine the likelihood of cancer metastasizing.

– University of Kansas Cancer Center

DOI: 10.1158/0008-5472.CAN-17-2194 Published December 2017

Health Indicators for Newborns of Breast Cancer Survivors May Vary by Cancer Type

In a study published in the International Journal of Cancer, researchers analyzed health indicators for children born to young breast cancer survivors in North Carolina.

– University of North Carolina Health Care System

International Journal of Cancer, Feb-2018

Health Indicators for Newborns of Breast Cancer Survivors May Vary by Cancer Type

In a study published in the International Journal of Cancer, researchers analyzed health indicators for children born to young breast cancer survivors in North Carolina.

– University of North Carolina Health Care System

International Journal of Cancer-2017

Hope for Patients with Lymphedema - New Surgical Treatment Offered at the CHUM

The Centre hospitalier de l’Université de Montréal (CHUM) is now offering a new surgical treatment for patients with lymphedema, swelling caused by the abnormal accumulation of lymph fluid in a body part, most often the arms or legs. Lymphovenous...

– Centre hospitalier de l'Université de Montréal (CHUM)

High Exposure to Radiofrequency Radiation Linked to Tumor Activity in Male Rats

High exposure to radiofrequency radiation (RFR) in rodents resulted in tumors in tissues surrounding nerves in the hearts of male rats, but not female rats or any mice, according to draft studies from the National Toxicology Program (NTP). The exposu...

– National Institute of Environmental Health Sciences (NIEHS)

Some Kids Saying No to Smoking Are Saying Yes to Vaping

Researchers found that adolescents not susceptible to smoking cigarettes and who thought e-cigarettes were less harmful were more likely to use e-cigarettes. This UNC study found that 26 percent of those surveyed were at high risk for future e-cigare...

– University of North Carolina Health Care System

Preventing Chronic Disease

University Hospitals in Cleveland Recruits Top Scientist to Lead Research at UH Seidman Cancer Center

Announcement of deputy director for research at University Hospitals Seidman Cancer Center in Cleveland.

Expert Available

– University Hospitals Cleveland Medical Center

Bacteria Play Critical Role In Driving Colon Cancers

Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer, a study led by a Johns ...

– Johns Hopkins Medicine

Cell Host & Microbe ; R01 CA151393, K08 DK087856, 5T32CA126607-05, P30 DK089502, P30 CA006973, P50 CA62924, 01DK080817, R01CA151325, R01GM111682; P30DK089502, P30CA006973, P50CA06292, K08 DK087856....

Embargo expired on 01-Feb-2018 at 14:00 ET

AHA Scientific Statement Highlights Intersection of Heart Disease and Breast Cancer

A new scientific statement issued by the American Heart Association underscores the commonalities between cardiovascular disease and breast cancer among women, and it calls for more focus on research and specialized treatment where the diseases overl...

– Ohio State University Wexner Medical Center


Embargo expired on 01-Feb-2018 at 05:00 ET

Why Basal Cell Tumors Return When Drug Treatment Stops

A new study pinpoints a mechanism that controls how basal cell cancers respond to treatment and offers new ideas for controlling this disease when it gets tricky.

– Michigan Medicine - University of Michigan

Cancer Cell; R21CA209166; R00AR059796; R01AR065409; R01CA087837; P30CA046592

Study Reveals How the Most Common DNA Mutation Happens

Shape-shifters aren’t just the stuff of fiction, they’re real—and they’re inside our DNA. In the Feb. 1 issue of the journal Nature, researchers describe how two mismatched bases in human DNA change shape in order to avoid the body’s natura...

– Ohio State University


UCLA Researchers Link a Relatively Unknown Gene to Early Emergence of Blood Diseases

UCLA researchers, in collaboration with the University of Iowa, discovered the contribution of a specific gene in the proper development of blood cells that give rise to hematopoietic stem cells. The findings identify a potential target for the devel...

– University of California, Los Angeles (UCLA), Health Sciences

Cell Reports

New International Practice Guidelines for Tamoxifen Treatment Based on CYP2D6 Genotype

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium (CPIC) published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Phar...

– Mayo Clinic

Clinical Pharmacology and Therapeutics

Simmons Cancer Center Researchers Part of Historic CAR-T Breakthrough

A historic study involving researchers from UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center demonstrates the effectiveness of CAR-T therapy, which uses genetically modified immune cells to treat acute lymphoblastic leukemia in child...

– UT Southwestern Medical Center

New England Journal of Medicine

On World Cancer Day, National Comprehensive Cancer Network Joins the Call for Equal Access to Reduce Premature Cancer Deaths by 25%

• World Cancer Day 2018 highlights the global equity gap in accessing early detection, treatment, and care services • UICC calls for more equal access to reduce premature cancer and non-communicable disease deaths by 25% by 2025 in line with WHO...

– National Comprehensive Cancer Network® (NCCN®)

Pre-Clinical Research Aided by Customized Collection Capabilities

Conversant Bio™ has partnered with Streck to provide cancer researchers with customized clinical plasma samples that are research-ready, allowing researchers to focus on their studies and not their sample collection processing and logistics.

– Streck

Landmark International Study: CAR T-Cell Therapy Safe and Effective in Children and Young Adults with Leukemia

Results of the global, multicenter, pivotal phase 2 study that led to the first FDA approval of a gene therapy/cell therapy approach known as CAR T-cell therapy, were published today in the New England Journal of Medicine.

– Childrens Hospital Los Angeles

New England Journal of Medicine

Embargo expired on 31-Jan-2018 at 17:00 ET

Researchers Identify Novel Drivers of Cancer Stem Cells That Lead to Colon Cancer Development and Growth

In breakthrough colon cancer research, scientists at Christiana Care Health System’s Center for Translational Cancer Research (CTCR) of the Helen F. Graham Cancer Center & Research Institute have discovered that over-expression of HOXA4 and HOXA9 g...

– Christiana Care Health System

Journal of Cellular Physiology, Vol. 233, Issue 2

New Magnet-Based Drug Delivery System Shows Promise for Cancer Treatment

A team of researchers at the University of Georgia has developed a non-invasive method of delivering drugs directly to cancerous tissue using magnetic forces, a form of treatment that could significantly reduce the toxic side effects of chemotherapy....

– University of Georgia

Nature Catalysis

UCI Scientists Develop New Chemical Tool to Study RNA Structures Inside Cells

University of California, Irvine scientists have created a new chemical tool that can analyze RNA structures within living cells. The technique could facilitate a better grasp of how RNA structures fold and form in cells, as well as help in the desig...

– University of California, Irvine

Nature Chemical Biology, Jan-2018

Self-Assembled “Hairy” Nanoparticles Could Give a Double Punch to Cancer


– Georgia Institute of Technology

Proceedings of the National Academy of Sciences; FA9550-16-1-0187; 1562075

Reduced Cancer Risk with Groundwater Treatment Requirements

Cancer risk due to arsenic exposure in Hopewell Township (Mercer County), New Jersey is reduced with the use of arsenic treatment systems.

– Rutgers School of Public Health

The Medical Minute: Health Risks of Smoking Go Beyond Lung Cancer

Doctors ask patients about smoking habits for the same reason they check weight, blood pressure, breathing and heart beat during a visit.

– Penn State Health Milton S. Hershey Medical Center

Sun Can Damage Skin Any Time of the Year

Skin damage from unprotected exposure to the sun can occur any time of year, even during the winter.

Expert Available

– Wake Forest Baptist Medical Center


Perlmutter Cancer Center Names New Directorof Gastrointestinal Medical Oncology

Paul E. Oberstein, MD, a nationally renowned clinician-scientist, will join NYU Langone Health and its Perlmutter Cancer Center on March 1 as director of Gastrointestinal (GI) Medical Oncology and assistant director of its recently established Pancre...

– NYU Langone Health

Rutgers Cancer Institute of New Jersey Doctors Named ‘Tops’ in Women’s Health

Several physicians at Rutgers Cancer Institute of New Jersey have earned recognition as a ‘Top Doctor for Women’s Health’ by Inside Jersey magazine, which recently released its annual listing.

– Rutgers Cancer Institute of New Jersey

Roswell Park’s Dr. Alan Klitzke Named 2018 President of the American College of Nuclear Medicine

The American College of Nuclear Medicine (ACNM) has named Alan Klitzke, MD, FACNM, as its 47th president.

– Roswell Park Comprehensive Cancer Center

Five Endocrine Society Leaders Join Its Governing Council

Five new Officers and Council Members will join the leadership of the Endocrine Society, the world’s largest global membership organization of endocrinologists dedicated to accelerating scientific innovation and improving health worldwide.

– Endocrine Society

Sharma named Vice Chair of SWOG Breast Committee

Priyanka Sharma, M.D., a breast cancer medical oncologist at The University of Kansas Cancer Center, has been named vice chair of SWOG’s Breast Committee.

– University of Kansas Cancer Center

NCCN Reaches New Records for Guidelines, Resources, and Programs

NCCN Reaches New Records for Guidelines, Resources, and Programs with eight million copies of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) downloaded by more than one million people across the globe in 2017.

– National Comprehensive Cancer Network® (NCCN®)

With $3.1m Grant From NIH, UCLA Scientists to Advance Adoption of Focal Therapy to Treat Prostate Cancer

UCLA researchers Dr. Leonard Marks and Shyam Natarajan will lead a $3.1 million research project grant awarded by the National Institutes of Health to advance the adoption of a promising new technology to treat men with prostate cancer. By helping to...

– University of California, Los Angeles (UCLA), Health Sciences

Higher Education Events

Forum to Give Latest on MDS Treatment

The Myelodysplastic Syndromes (MDS) Foundation and The University of New Mexico Comprehensive Cancer Center are sponsoring a free public information forum about MDS. Presenters include Cecilia Arana Yi, MD, from the UNM Cancer Center, and Emily A. Kn...

– University of New Mexico Comprehensive Cancer Center

Expert Pitch

Streck’s Scientific Manager for Immunology and Biomarkers R&D Division Focuses on New Product Development Surrounding Liquid Biopsy

– Streck

Streck’s Director of New Product Development Focuses on Innovation in Molecular Analysis

– Streck





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