Is this email not displaying correctly? View it in your browser.
 
Newswise - News for Journalists
Newswise Special Wire
Tuesday, February 13, 2018

Public edition | newswise.com

Newswise Cancer Research Wire for 13-Feb-2018
 

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.



Phase II Trial Demonstrates Activity of Durvalumab in Patients with Recurrent or Metastatic Head and Neck Cancer

Analysis of the phase II CONDOR trial indicates that the immune checkpoint inhibitor durvalumab is tolerable among heavily pre-treated patients with recurrent or metastatic head and neck cancer and has the potential to slow growth in tumors with low ...

– American Society for Radiation Oncology (ASTRO)

Multidisc Head and Neck Cancers Symposium, Feb-2018

Embargo expired on 13-Feb-2018 at 12:00 ET


Nivolumab Immunotherapy Safe and Feasible During Chemoradiation for Advanced Head and Neck Cancer

Analysis of a clinical trial, RTOG Foundation 3504, finds that nivolumab immunotherapy can be administered safely in conjunction with radiation therapy and chemotherapy for patients with newly diagnosed local-regionally advanced head and neck cancers...

– American Society for Radiation Oncology (ASTRO)

Multidisc Head and Neck Cancers Symposium, Feb-2018

Embargo expired on 13-Feb-2018 at 12:00 ET


Cabozantinib Shows Significant Activity in the First Line for Differentiated Thyroid Cancer

Results of a new phase II clinical trial indicate that cabozantinib offers an active therapy option for patients with differentiated thyroid cancer (DTC) that has progressed following surgery and treatment with radioactive iodine (RAI). Thirty-four o...

– American Society for Radiation Oncology (ASTRO)

Multidisc Head and Neck Cancers Symposium, Feb-2018

Embargo expired on 13-Feb-2018 at 00:05 ET


Lower-Dose Radiation Therapy Effective and Safe for HPV-Related Head and Neck Cancer After Induction Chemotherapy, Trial Finds

Results of the phase II OPTIMA clinical trial indicate that patients with head and neck cancers associated with the human papillomavirus (HPV), including those with advanced nodal disease, can receive substantially lower radiation doses safely and ef...

– American Society for Radiation Oncology (ASTRO)

Multidisc Head and Neck Cancers Symposium, Feb-2018

Embargo expired on 13-Feb-2018 at 12:00 ET


Clues to Aging Found in Stem Cells' Genomes

Little hints of immortality are lurking in the stem cells of fruit flies

– University of Michigan

eLife


Light-Activated Cancer Drugs Without Toxic Side Effects: Fresh Insight

Future cancer drugs that are activated by light and don’t cause the toxic side-effects of current chemotherapy treatments are closer to becoming a reality, thanks to new research made possible by the Monash Warwick Alliance, an intercontinental col...

– University of Warwick

Chemistry - A European Journal


Complimentary Press Registration Available for 2018 State-of-the-Art Clinical Symposium

The American College of Rheumatology (ACR) welcomes members of the press to write about rheumatology research presented the State-of-the-Art Clinical Symposium (SOTA) in Chicago, IL, on April 13-15.

– American College of Rheumatology (ACR)

SOTA 2018


Managing Postoperative Pain in the Cancer Patient

In the March issue of Diseases of the Colon & Rectum, surgeons from Australia discuss postoperative pain control pain control following one of the most extensive operations performed for pelvic cancer. In an era where many studies have shown that pa...

– Diseases of the Colon and Rectum Journal

Diseases of the Colon & Rectal

Embargo expired on 12-Feb-2018 at 10:00 ET


Study Suggests Way to Attack Deadly, Untreatable Nerve Tumors

Genomic profiling of mostly untreatable and deadly nerve sheath tumors led scientists to test a possible therapeutic strategy that inhibited tumor growth in lab tests on human tumor cells and mouse models, according to research in the journal Cancer ...

– Cincinnati Children's Hospital Medical Center

Cancer Cell, Feb-2018

Embargo expired on 12-Feb-2018 at 12:00 ET


Family History Increases Breast Cancer Risk Even in Older Women: Weighing Screening Options

Family history of breast cancer continues to significantly increase chances of developing invasive breast tumors in aging women — those ages 65 and older, according to research published in JAMA Internal Medicine. The findings could impact mammogra...

– Georgetown Lombardi Comprehensive Cancer Center

JAMA Internal Medicine

Embargo expired on 12-Feb-2018 at 11:00 ET


Experimental Therapy Restores Nerve Insulation Damaged by Disease

When the body attacks its own healthy tissues in an autoimmune disease, peripheral nerve damage handicaps people and causes persistent neuropathic pain when insulation on healing nerves doesn’t fully regenerate. Unfortunately, there are no effectiv...

– Cincinnati Children's Hospital Medical Center

Nature Medicine, Feb-2018

Embargo expired on 12-Feb-2018 at 11:00 ET


Medicaid Expansion in Kentucky Improves Breast Cancer Care for Women 20 to 64 Years Old

Kentucky researchers report rates of diagnosis of early stage disease and utilization of less invasive operations have increased since 2014.

– American College of Surgeons (ACS)

Journal of the American College of Surgeons

Embargo expired on 12-Feb-2018 at 11:00 ET


Newly Identified Potential Therapeutic Approach Kills Triple-Negative Breast Cancer Cells in Pre-Clinical Study

Triple-negative breast cancer (TNBC), a highly aggressive, relapse-prone cancer that accounts for one-fourth of all breast cancers, could be the focus of a new area of study for immune checkpoint blockade therapy. A team of researchers at The Univer...

– University of Texas M. D. Anderson Cancer Center

Cancer Cell

Embargo expired on 12-Feb-2018 at 12:00 ET


NIR Light May Identify Breast Cancer Patients Who Will Benefit Most from Chemotherapy

A new optical imaging system developed at Columbia University uses red and near-infrared light to identify breast cancer patients who will respond to chemotherapy. The imaging system may be able to predict response to chemotherapy as early as two wee...

– Columbia University School of Engineering and Applied Science

Radiology Feb 12 2018

Embargo expired on 12-Feb-2018 at 00:15 ET


Obesity Associated with Longer Survival for Men with Metastatic Melanoma

Obese patients with metastatic melanoma who are treated with targeted or immune therapies live significantly longer than those with a normal body mass index (BMI), investigators report in a study published in Lancet Oncology of 1,918 patients in six ...

– University of Texas M. D. Anderson Cancer Center

Lancet Oncology

Embargo expired on 12-Feb-2018 at 18:30 ET


Smart Bomb Virus Shows Promise as Brain Tumor Immunotherapy

A common cold virus engineered to attack the most common and deadly of brain tumors allowed 20 percent of patients with recurrent glioblastoma to live for three years or longer, researchers from The University of Texas MD Anderson Cancer Center repor...

– University of Texas M. D. Anderson Cancer Center

Journal of Clinical Oncology

Embargo expired on 12-Feb-2018 at 16:00 ET


Huntington's Disease Provides New Cancer Weapon

Patients with Huntington’s disease, a fatal genetic illness that causes the breakdown of nerve cells in the brain, have up to 80 percent less cancer than the general population.Northwestern Medicine scientists have discovered why Huntington’s is ...

– Northwestern University

EMBO Reports; R35CA197450


Researchers Inhibit Cancer Metastases via Novel Steps

In one of the first successes of its kind, researchers have inhibited the spreading of cancer cells from one part of the body to another. In doing so, they relied on a new model of how cancer metastasizes that emphasizes epigenetics, which examines h...

– Case Western Reserve University

Nature Medicine; Case Comprehensive Cancer Center; Liddy Shriver Sarcoma Initiative; QuadW Foundation; Sarcoma Foundation of America; NIH


Neutron Study of Glaucoma Drugs Offers Clues About Enzyme Targets for Aggressive Cancers

A team of researchers from ORNL’s Energy and Transportation Science Division is using neutron imaging to study particulate filters that collect harmful emissions in vehicles. A better understanding of how heat treatments and oxidation methods can ...

– Oak Ridge National Laboratory

Structure


New Immunotherapy Combination Tolerable, Effective in Patients with Advanced Kidney Cancer

Combining an anti-angiogenesis agent, which blocks blood vessel formation, with an immunotherapy agent, was found to have promising anti-tumor activity and no unexpected side effects in an early-phase clinical trial in patients with advanced kidney c...

– Georgetown Lombardi Comprehensive Cancer Center

The Lancet Oncology

Embargo expired on 10-Feb-2018 at 13:10 ET


Placebo Pills Prescribed Honestly Help Cancer Survivors Manage Symptoms

Fatigue in cancer survivors is significantly reduced by placebo pill, even when it is known it is a fake pill.

– University of Alabama at Birmingham

Nature Scientific Reports, Feb-2018

Embargo expired on 09-Feb-2018 at 05:00 ET


Increased Breast Cancer Risk Seen in Postmenopausal Women with High Body-Fat Levels Despite Normal BMI

The risk of invasive breast cancer is increased in postmenopausal women with a normal body mass index (BMI) but higher levels of body fat, meaning that a large portion of the population has an unrecognized risk of developing cancer.

– Memorial Sloan Kettering Cancer Center

Obesity and Cancer: Mechanisms Underlying Etiology and Outcomes


Clock Protein Controls Daily Cycle of Gene Expression by Regulating Chromosome Loops

It’s well known that the human body functions on a 24-hour, or circadian, schedule. The up-and-down daily cycles of a long-studied clock protein called Rev-erb coordinates the ebb and flow of gene expression by tightening and loosening loops in chr...

– Perelman School of Medicine at the University of Pennsylvania

R01 DK45586, NIH R01 DK106027, NIH T32GM007170, T32 GM008216, F30 DK112507


Blood Test Plus Ultrasound Boosts Liver Cancer Detection by 40 Percent

Combining ultrasound imaging with a blood test for high alpha fetoprotein (AFP) levels improves detection of early-stage liver cancer by as much as 40 percent, researchers at UT Southwestern’s Simmons Cancer Center found.

– UT Southwestern Medical Center


Study Shows Liver Cells with Whole Genome Duplications Protect Against Cancer

Researchers at the Children’s Medical Center Research Institute (CRI) at UT Southwestern have discovered that cells in the liver with whole genome duplications, known as polyploid cells, can protect the liver against cancer.

– UT Southwestern Medical Center

Developmental Cell


Physical Inactivity Linked to Higher Risk of Lung, Head/Neck Cancers, Roswell Park shows

Roswell Park Comprehensive Cancer Center-led research teams have identified a direct association between physical inactivity and two different types of cancer: lung cancer and head/neck cancer — adding to a growing list of cancers linked to sedenta...

– Roswell Park Comprehensive Cancer Center

Cancer Treatment and Research Communications; European Archives of Oto-Rhino-Laryngology; P30CA16056; T32CA108456


New Tool Helps Physicians Estimate Survival for Patients with Cancers That Have Spread to Bone

A simple three-factor tool can help doctors estimate survival time in patients with long bone metastases (LBMs)—advanced cancer that has spread to the bones of the limbs, reports a study in the February 7, 2018, issue of The Journal of Bone & Joint...

– Wolters Kluwer Health: Lippincott Williams and Wilkins

Journal of Bone and Joint Surgery


Scientists Take Big Step Toward Stopping Cancer Metastasis

TSRI scientists identify molecule that fuels cancer metastasis.

– Scripps Research Institute

Oncogene, Jan. 2018; R01CA157792; R01CA105412; R01CA034282


Researchers Uncover How Cancer Stem Cells Drive Triple-Negative Breast Cancer

Cleveland Clinic researchers have published findings in Nature Communications on a new stem cell pathway that allows a highly aggressive form of breast cancer - triple-negative breast cancer - to thrive.

– Cleveland Clinic

Nature Communications; R21 CA191263


Turning Up the Heat on Chemotherapy

While cancer treatment advances are being made in precision medicine and immunotherapy, a unique combination of traditional therapies can also provide some patients benefit. A Rutgers Cancer Institute of New Jersey expert shares more about an approa...

– Rutgers Cancer Institute of New Jersey


American College of Rheumatology Recommends Biosimilar Use in New White Paper

The American College of Rheumatology (ACR) has published a new white paper, “The Science Behind Biosimilars – Entering a New Era of Biologic Therapy." The paper encourages providers to incorporate these drugs into treatment plans of patients with...

– American College of Rheumatology (ACR)


The Medical Minute: Helping Children Thrive After Cancer

Childhood cancer survivors are at a higher risk of developing physical and emotional difficulties once their treatment is complete. That's why it’s important to connect them with follow-up care and resources.

– Penn State Health Milton S. Hershey Medical Center


A Boost for Older Hodgkin Lymphoma Patients

Results of a phase II study presented at the recent American Society of Hematology Annual Meeting shows the best outcomes to date for older Hodgkin lymphoma patients treated with brentuximab vedotin before and after AVD chemotherapy. A presenting au...

– Rutgers Cancer Institute of New Jersey

American Society of Hematology Annual Meeting, 2017


UPMC Researchers Solving Treatment Resistance in Most Common Breast Cancer

For the first time researchers have identified recurrent ESR1 fusion proteins in human breast cancer, to understand how they function and help lead to improved treatments for the disease.

– Health Sciences at the University of Pittsburgh

Annals of Oncology; P30CA047904, UL1-RR024153, UL1-TR000005, SAC150021, 2T32GM008424-21, 5F30CA203095


Cell Phone Radiation and Tumors, World Cancer Day 2018, Gut Bacteria and Colon Cancer, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

– Newswise


Matchmaking for Cancer Care

Computer scientists from the University of Delaware and Georgetown University have developed a new system to rapidly determine which cancer drugs are likely to work best given genetic markers for a patent – the first publicly available system of it...

– University of Delaware

PLOS One


New Algorithm Decodes Spine Oncology Treatment

Every kind of cancer can spread to the spine, yet two physician-scientists who treat these patients describe a paucity of guidance for effectively providing care and minimizing pain. To resolve the confusion and address the continually changing lands...

– Michigan Medicine - University of Michigan

The Lancet Oncology


Starving Liver Cancer

Scientists at the University of Delaware and the University of Illinois at Chicago have found a new way to kill liver cancer cells and inhibit tumor growth. This research could accelerate the development of new treatments for liver cancer, which is c...

– University of Delaware

Nature Communications


IU Advances Fight Against Hepatitis B with 'Virus-Cracking' Molecules

Indiana University researchers have found that certain molecules -- several of which are currently under clinical trial -- are able to "crack" the protective shell of the hepatitis B virus, suggesting it may be possible to attack the virus after its ...

– Indiana University

eLife; R01-AI067417-04


Policy and Public Affairs


ASTRO Applauds Congressional Leaders for Extending the Radiation Oncology Payment Freeze

The American Society for Radiation Oncology (ASTRO) today applauded congressional leaders for the passage of legislation to freeze payment rates for key radiation oncology services delivered in freestanding clinics.

– American Society for Radiation Oncology (ASTRO)


Announcements


Rutgers Cancer Institute of New Jersey at University Hospital Expands Oncology Leadership

New oncology leaders for Rutgers Cancer Institute of New Jersey at University Hospital in Newark have been named, further enhancing the facility’s expertise and ability to deliver National Cancer Institute (NCI)-designated Comprehensive Cancer Cent...

– Rutgers Cancer Institute of New Jersey


Penn Immunologist Awarded SU2C Funding to Lead Team-Based Investigation of Gynecologic Cancer Therapies

E. John Wherry, PhD, a cancer and immunology researcher at the Perelman School of Medicine at the University of Pennsylvania and one of the most highly cited investigators in his field, has been awarded a “Convergence 2.0” research grant by Stand...

– Perelman School of Medicine at the University of Pennsylvania


KU Cancer Center named “High-Performing Site” by National Cancer Institute

The University of Kansas Cancer Center was recently recognized as a “high-performing site” by the National Cancer Institute (NCI).

– University of Kansas Cancer Center

Tips

CUSTOMIZE YOUR FAVORITES WITH "MY READING LIST"

MY CHANNELS  |  SAVED ARTICLES  |  MY SOURCES  |  MY EXPERTS

MORE CHANNELS:
JOURNAL NEWS   |  TRENDS AND TOP STORIES   |  LOCAL NEWS  |  MEDICAL and SCIENTIFIC MEETINGS

Support
 Subscribe/Unsubscribe
 Edit My Preferences
 Comments/Suggestions
 Contact Us
 
Services
 Newswise Home
 Newswise Contact Directory
 Expert Queries
 Presspass Application

More News from:

  Newswise

 Michigan Medicine - University of Michigan

 Diseases of the Colon and Rectum Journal

 University of Alabama at Birmingham

 Health Sciences at the University of Pittsburgh

 Penn State Health Milton S. Hershey Medical Center

 Wolters Kluwer Health: Lippincott Williams and Wilkins

 University of Texas M. D. Anderson Cancer Center

 UT Southwestern Medical Center

 Northwestern University

 Oak Ridge National Laboratory

 University of Warwick


Subscribe / Unsubscribe
Edit my preferences

© 2018 Newswise, Inc. All Rights Reserved.

215 E. 5th St. SW, Charlottesville VA 22903 | 434-296-9417

 Contact Us