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Newswise Special Wire
Tuesday, February 20, 2018

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Newswise Cancer Research Wire for 20-Feb-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Hospital Charges For Outpatient Cancer Care Highly Variable, Medicare Billing Records Show

An analysis of recent Medicare billing records for more than 3,000 hospitals across the United States shows that charges for outpatient oncology services such as chemo infusion or radiation treatment vary widely and exceed what Medicare will pay by t...

– Johns Hopkins Medicine

Journal of Managed Care

Researchers Discover Novel Mechanism Linking Changes in Mitochondria to Cancer Cell Death

Researchers at the University of Notre Dame discovered that the activation of a specific enzyme may help suppress the spread of tumors.

– University of Notre Dame

Nature Cell Biology

Highly Mutated Protein in Skin Cancer Plays Central Role in Skin Cell Renewal

Researchers have shown for the first time that a key protein called KMT2D involved in the epigenetic regulation of gene expression guides this renewal.

– Perelman School of Medicine at the University of Pennsylvania

Genes & Development; K08AR070289, P01AG031862, GM110174, CA196539, F31 GM123744-01, P30AR069589-01

New Prostate Cancer Risk Model Could Better Guide Treatment

A new model developed by Michigan Medicine researchers could change treatment guidelines for nearly two-thirds of men with localized prostate cancer.

– Michigan Medicine - University of Michigan

Journal of Clinical Oncology; Prostate Cancer Foundation Young Investigator Award; Department of Defense

Studying Mitosis’ Structure to Understand the Inside of Cancer Cells

Cell division is an intricately choreographed ballet of proteins and molecules that divide the cell. During mitosis, microtubule-organizing centers assemble the spindle fibers that separate the copying chromosomes of DNA. While scientists are familia...

– Biophysical Society

62nd Biophysical Society Annual Meeting

Embargo expired on 18-Feb-2018 at 08:00 ET

Using Mutant Bacteria to Study How Changes in Membrane Proteins Affect Cell Functions

Phospholipids are water insoluble “building blocks” that define the membrane barrier surrounding cells and provide the structural scaffold and environment where membrane proteins reside. During the 62nd Biophysical Society Annual Meeting, held Fe...

– Biophysical Society

62nd Biophysical Society Annual Meeting

Embargo expired on 18-Feb-2018 at 08:00 ET

Ras Protein’s Role in Spreading Cancer

Protein systems make up the complex signaling pathways that control whether a cell divides or, in some cases, metastasizes. Ras proteins have long been the focus of cancer research because of their role as “on/off switch” signaling pathways that ...

– Biophysical Society

62nd Biophysical Society Annual Meeting

Embargo expired on 18-Feb-2018 at 08:00 ET

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– Newswise

'Click Chemistry' Reactions May Boost Cancer-Fighting Drug Potency

Researchers at The Scripps Research Institute (TSRI) have developed a quick and easy way to simultaneously modify dozens of drugs or molecules to improve their disease-fighting properties.

– Scripps Research Institute

Journal of the American Chemical Society, Feb. 2018; R01 GM117145; R01 GM111938; R01GM113046

OU and Mercy Test New Models

An OU and Mercy Hospital Oklahoma City research team is set to begin the largest breast cancer clinical trial ever performed in Oklahoma. The team has developed new breast cancer risk prediction models based on a computer-aided image feature analy...

– University of Oklahoma, Gallogly College of Engineering

New Imaging Technology May Help Predict Aggressiveness of Lung Cancer

Case Western Reserve and Cleveland Clinic are leading development of a computerized tissue-imaging program that could soon help identify which lung cancer patients are likely to face an earlier recurrence of the disease.

– Case Western Reserve University

CRISPR-based Technology Can Detect Viral DNA

Technology that’s been used to edit genomes can also spot snippets of DNA. Such detective work may enable rapid, reliable ways to identify infections and cancer.

– Howard Hughes Medical Institute (HHMI)

Science, Feb 2018

Embargo expired on 15-Feb-2018 at 14:00 ET

Affordable Care Act Lowered Uninsured Rate for Cancer Survivors

The percentage of cancer survivors without health insurance decreased substantially after implementation of the Affordable Care Act (ACA), reports a study in the March issue of Medical Care, published by Wolters Kluwer.

– Wolters Kluwer Health: Lippincott Williams and Wilkins

Medical Care

Race, Insurance Status Linked to Job Loss After Breast Cancer

Job loss following early-stage breast cancer diagnosis is associated with race and insurance status, but not with any clinical or treatment-related factors, finds a new study from the Brown School at Washington University in St. Louis.Not only were a...

– Washington University in St. Louis

Cancer Feb. 13, 2018

Cutting Off Cervical Cancer’s Fuel Supply Stymies Tumors

Researchers at Washington University School of Medicine in St. Louis have shown that cervical tumors that don’t respond to radiation may be vulnerable to therapies that also attack the cancer’s fuel supply.

– Washington University in St. Louis

Cancer Research

New Stem-Cell Based Stroke Treatment Repairs Damaged Brain Tissue

A team of researchers at the University of Georgia's Regenerative Bioscience Center and ArunA Biomedical, a UGA startup company, have developed a new treatment for stroke that reduces brain damage and accelerates the brain's natural healing tendencie...

– University of Georgia

Translational Stroke Research

Catching Up to Brain Cancer

University of Delaware researchers have produced a new and freely available computer program that predicts cancer cell motion and spread with high accuracy. The system gives researchers a faster way of examining rapidly spreading brain cancer tumors ...

– University of Delaware

BMC Systems Biology

Cancer Researcher's Life Saved by CAR-T Treatment

Dr. Woodring Wright, a UT Southwestern Professor of Cell Biology who studies the end caps of chromosomal DNA, called telomeres, hoping to find ways to fight aging and cancer, had multiple myeloma.

– UT Southwestern Medical Center

CAR-T Clinical Trial Enrolling Multiple Myeloma Patients

UT Southwestern Medical Center is one of nine exclusive sites in the country enrolling multiple myeloma patients for a clinical trial of the CAR-T “living drug” therapy for cancer.

– UT Southwestern Medical Center

Cabozantinib Shows Promise as First Line Treatment for Differentiated Thyroid Cancer

A kinase inhibitor called cabozantinib could be a viable therapy option for patients with metastatic, radioactive iodine-resistant thyroid cancer. In a trial initiated and led by the Abramson Cancer Center and the Perelman School of Medicine at the U...

– Perelman School of Medicine at the University of Pennsylvania

2018 Multidisciplinary Head and Neck Cancers Symposium

A Synthetic Cell That Produces Anti-Cancer Drugs Within a Tumor

Researchers have successfully treated a cancerous tumor using a “nano-factory” – a synthetic cell that produces anti-cancer proteins within the tumor tissue. The synthetic cell could one day be an important part in the personalized medicine tre...

– American Technion Society

Advanced Healthcare Materials


Biospecimen Core Resource Wins NIH Contract to Further Cancer Research

The Biospecimen Core Resource (BCR) in The Research Institute at Nationwide Children’s Hospital has received a new $4.5 million federal contract — with the potential of reaching more than $49.9 million over five years — to accept, process, ensu...

– Nationwide Children's Hospital


URI Study Aims to Find Carcinogen Damage Before Cancer Develops

The five-year, $2.1 million study will examine mutational spectra of environmental toxins.

– University of Rhode Island

WVU Researcher Wins National Award; Examines Use of Multiple Medications Among Older Cancer Survivors

With the help of a new award, a West Virginia University researcher is examining the prevalence and hazards of potentially inappropriate medication prescribing among elderly cancer survivors.

– West Virginia University

Embargo expired on 19-Feb-2018 at 08:30 ET

American College of Rheumatology Awarded Grant to Focus on Projects That Curb Health Disparities

The American College of Rheumatology was awarded a grant from the American Society of Association Executives to develop a new program, Uniting Collaborators for Innovation (UCOIN), that focuses on creating member-led initiatives that diminish racial ...

– American College of Rheumatology (ACR)

Childhood Cancer Survivors, Hospital Host Fundraiser for Research

The Children’s Hospital University of Illinois will host an annual head-shaving event to raise money for the St. Baldrick’s Foundation.

– University of Illinois at Chicago





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