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Newswise Special Wire
Tuesday, March 6, 2018

Public edition |

Newswise Cancer Research Wire for 06-Mar-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Preventing Exhaustion in Immune Cells Boosts Immunotherapy in Mice

Immunotherapy does not work for a majority of cancer patients. Preventing or reversing metabolic exhaustion in cancer-killing T-cells could boost its effectiveness.

– Health Sciences at the University of Pittsburgh

Journal of Experimental Medicine; SKF-015-036, SU2C-AACR-IRG-04-16, DP2AI136598, T32CA082084, F99CA222711 and P30CA047904.

Embargo expired on 06-Mar-2018 at 09:00 ET

Controlling Ceramides Could Help Treat Heart Disease

SBP researchers have discovered that accumulation of ceramides—a type of lipid (fat)— plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition that often occurs in patients with diabetes and obesity. The study, published today ...

– Sanford Burnham Prebys Medical Discovery Institute

R01 HL054732; R01 HL132241 ; R21 HL80811

Embargo expired on 06-Mar-2018 at 12:00 ET

Repurposed Parasite Drug New Weapon Against Mesothelioma

Anthelmintic drug already approved to treat infections of pinworm parasite was shown to effectively impair both mesothelioma cell growth and migration.

– Sbarro Health Research Organization (SHRO)

Journal of Cell Physiology; Mesothelioma Applied Research Foundation

Cognitive Decline Prevalent Among Elderly Patients with Hematologic Cancers, Study Finds

A sizable percentage of elderly patients with blood-related cancers such as leukemia and multiple myeloma are apt to show signs of diminished cognitive functioning

– Dana-Farber Cancer Institute

JAMA Oncology

CRISPR Enhances Cancer Immunotherapy

Scientists at Washington University School of Medicine in St. Louis have used the gene-editing technology CRISPR to engineer human T cells that can attack human T cell cancers. The new approach also eliminates a dangerous side-effect called graft-ver...

– Washington University in St. Louis


How a Yeast Cell Helps Crack Open the “Black Box” Behind Artificial Intelligence

UC San Diego School of Medicine researchers developed a visible neural network and used it to build DCell, a virtual model of a functioning brewer’s yeast cell. To do this, they amassed all knowledge of cell biology in one place and created a hiera...

– University of California San Diego Health

Nature Methods

Embargo expired on 05-Mar-2018 at 11:00 ET

Swept Under the Rug: New Report Reveals Toxics in European Carpets Threatening Health, Environment and Circular Economy

Toxic substances linked to a range of adverse health impacts can be present in carpets sold in the European Union (EU), the European Public Health Alliance (EPHA) and the Health and Environment Alliance (HEAL) warned today following a new study by An...

– Health and Environment Alliance (HEAL)

Many Women Misjudge How They'll Feel After Mastectomy

Women who have one or both breasts removed to treat cancer may have unrealistic expectations about how they’ll feel after that surgery and after breast reconstruction, if they choose that option, a U.S. study suggests. Newsmax Article

– Yale Cancer Center

JAMA Surgery

Multimodal Approach Improves Survival in Aggressive Prostate Cancer


– University of California, Los Angeles (UCLA), Health Sciences

The Journal of the American Medical Association

Researchers Identify Genetic ‘Seeds’ of Metastatic Breast Cancer

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified genetic clues that explain how breast cancer spreads, or metastasizes – findings that may lead to better treatments or approaches to prevent its spread ...

– University of North Carolina Health Care System

Journal of Clinical Investigation, February-2018

A Helping Hand from a Compassionate Team at Rutgers Cancer Institute of New Jersey

There’s more to caring for cancer patients than treatments and doctor’s visits. At Rutgers Cancer Institute of New Jersey the Social Work Department is dedicated to treating the ‘whole’ patient by helping them navigate important issues one m...

– Rutgers Cancer Institute of New Jersey

Comparison Shows Value of DNA Barcoding in Selecting Nanoparticles

The first direct comparison of in vitro and in vivo screening techniques for identifying nanoparticles that may be used to transport therapeutic molecules into cells shows that testing in lab dishes isn’t much help in predicting which nanoparticles...

– Georgia Institute of Technology

ACS Nano Letters

Deeper Look at Biopsy Exposes Mutation Ready to Ambush Drug Combination

A powerful resistance mutation that appeared to emerge in melanoma after a patient received a targeted therapy combination, instead was lurking in the tumor all along, primed to thwart treatment before it began, researchers at The University of Texas...

– University of Texas M. D. Anderson Cancer Center

Here's How Viruses Inactivate the Immune System, Causing Cancer

"The same mechanisms that viruses use to cause cancer may be key in combating tumors with immune-based therapies or in keeping cancer from developing in the first place," says Sharon Kuss-Duerkop, PhD.

– University of Colorado Cancer Center

Viruses; T32 AI052066; R01 AI091968 ; R01 DE026125

Simplifying Samples

Using nanotechnology, a team of researchers at Washington University in St. Louis has eliminated the need for refrigeration for biomarkers used in medical diagnostic testing. The researchers recently gave their new tech a real-world test by sending i...

– Washington University in St. Louis

Chemistry of Materials

JHU Scientists Discover How Extremophiles Flourish in Stressful Environments

RNA makes salt-loving microbes known as “extremophiles” highly resistant to the phenomenon oxidative stress – the uncontrollable production of unstable forms of oxygen called “free radicals,” which can negatively affect DNA, proteins, and l...

– Johns Hopkins University

Journal of Bacteriology, Feb-2018; FA9950-14-1-0118

March is National Colorectal Cancer Awareness Month

With colorectal cancer tabbed as the third leading cause of cancer death among both men and women in the nation, experts from Rutgers Cancer Institute discuss the benefits of screening.

Expert Available

– Rutgers Cancer Institute of New Jersey

Johns Hopkins Researchers Invent New Technology for Cancer Immunotherapy

Johns Hopkins researchers have invented a new class of cancer immunotherapy drugs that are more effective at harnessing the power of the immune system to fight cancer. This new approach, which was reported in Nature Communications, results in a signi...

– Johns Hopkins Medicine

Nature Communications; R01CA184199, SPOREP50DE019032

Researchers Move Closer to Improved Method of Detecting Breast Cancer

Engineering researchers at the University of Arkansas have moved closer to developing an alternative method of detecting and possibly treating breast cancer. The researchers work with pulsed, terahertz imaging, a type of electromagnetic radiation tec...

– University of Arkansas, Fayetteville

Journal of Biomedical Optics

Diverse Role of CDK9 Gene in Cell Regulation Continues to Reveal Cancer Treatment Targets 25 Years After Discovery

A gene discovered by Temple University researchers has proved to be an important target for cancer therapy, with the discovery of its roles in controlling cell proliferation, differentiation, apoptosis, and DNA repair.

– Sbarro Health Research Organization (SHRO)

Journal of Experimental and Clinical Cancer Research


在美国心脏病学会(American College of Cardiology)第67届年度科学会议上发表的Mayo Clinic的一项研究表明,接受乳腺癌(breast cancer)或淋巴瘤(lymphoma)治疗的患者发生充血性心力衰竭(congestive h...

– Mayo Clinic

Mayo Clinic presented at the 67th Annual Scientific Meeting

Fight Colorectal Cancer Launches Annual One Million Strong Campaign Alongside Courageous Celebrities, Supporters

Yesterday Fight Colorectal Cancer rang the NASDAQ opening bell alongside survivors and partners from the PGA TOUR in Tucson and also from the Times Square NASDAQ tower on the heels of March, Colorectal Cancer Awareness Month. Today, the country’s l...

– Fight Colorectal Cancer

The Medical Minute: Are You at Increased Risk for Colorectal Cancer?

Most people know doctors recommend a colonoscopy at age 50 to screen for colorectal cancers. What they might not realize is that earlier screening may be necessary if they have a family history of colorectal cancer or other diseases.

– Penn State Health Milton S. Hershey Medical Center

A One-Stop Shop for Colorectal Cancer Care

UAB Medicine recently established a colorectal oncology clinic to provide a hassle-free experience for diagnosis and treatment.

– University of Alabama at Birmingham

New Procedure Brings Chemo to Melanoma

Surgical oncologist Dr. Cristina O’Donoghue is one of less than 30 surgeons in the country to trained to perform isolated limb infusion, which delivers high doses of chemotherapy to an affected arm or leg but not the rest of the body

Expert Available

– Rush University Medical Center

Mayor probabilidad de insuficiencia cardíaca en supervivientes de cáncer de mama y linfoma

Los pacientes con tratamiento previo para cáncer de mama o linfona tienen un riesgo tres veces mayor de sufrir insuficiencia cardíaca congestiva, que los pacientes sin cáncer. La insuficiencia cardíaca congestiva ocurre cuando el músculo cardía...

– Mayo Clinic

LXVII Annual Scientific Session

Embargo expired on 28-Feb-2018 at 08:15 ET

Heart Failure More Likely for Some Breast Cancer and Lymphoma Survivors

Patients who were treated for breast cancer or lymphoma are more than three times at risk for developing congestive heart failure, compared with patients who did not have cancer. Congestive heart failure is when the heart muscle does not pump blood a...

– Mayo Clinic

American College of Cardiology’s 67th Annual Scientific Session

Embargo expired on 28-Feb-2018 at 08:00 ET

Newly Discovered CRISPR Mechanism May Help Prevent Dangerous Errors

Researchers at The Ohio State University report that they’ve figured out the mechanism by which the CRISPR gene-editing enzyme Cas9 determines where and when to cut DNA strands—a discovery that could help prevent gene-cutting errors.

– Ohio State University

Journal of the American Chemical Society

New Method Accelerates Studies on Carbohydrate Biology

The breakthrough may expand research on the roles of glycans in human diseases, including cancers.

– Scripps Research Institute

Nature Communications, Feb. 2018; GM093282; GM113046 ; GM103390; U1606403

Bristol-Myers Squibb Announces Expansion of the International Immuno-Oncology Network (II-ON) with Addition of Yale Cancer Center

Bristol-Myers Squibb Company today announced that Yale Cancer Center has joined the International Immuno-Oncology Network (II-ON), a global peer-to-peer collaboration between Bristol-Myers Squibb and academia that aims to advance translational Immuno...

– Yale Cancer Center

A Synthetic Approach to Helping the Immune System Thwart Infections

Yale researchers have developed a set of synthetic molecules that may help boost the strength of a key, virus-fighting protein.

– Yale Cancer Center

New Technique Predicts Gene Resistance to Cancer Treatments

Yale School of Public Health researchers have developed a new method to predict likely resistance paths to cancer therapeutics, and a methodology to apply it to one of the most frequent cancer-causing genes.

– Yale Cancer Center


Breast Cancer Breakthrough May Have Been Found in Connecticut

A big breakthrough in the battle against breast cancer may have been found in Connecticut.

– Yale Cancer Center

Mayo Clinic Social Media Campaign Highlights Colorectal Cancer Awareness, Prevention

To kick off March as National Colorectal Cancer Awareness Month, Mayo Clinic today announced the launch of a social media campaign to raise awareness about colorectal cancer, and the importance of screening and early detection to save lives.

– Mayo Clinic

Jekyll and Hyde and Seek

Writing in the February 27 online issue of Science Signaling, researchers at University of California San Diego School of Medicine and Moores Cancer Center describe how a signaling protein that normally suppresses tumors can be manipulated (or re-pro...

– University of California San Diego Health

Science Signaling

Fred Hutchinson Cancer Research Center Tipsheet - Feb. 2018

The February Fred Hutch tip sheet includes story ideas ranging from cancer immunotherapy to cloud computing, flu prevention for cancer patients, cystine-dense peptides found in many deadly venoms, gene therapies, serendipitous findings and more.

– Fred Hutchinson Cancer Research Center


ACSM to Convene International, Multidisciplinary Experts on Exercise and Cancer

Roundtable will update exercise recommendations for cancer survivors, add prevention guidance

– American College of Sports Medicine (ACSM)

NCCN Conference to Address Value-Based Healthcare Models, Payer Perspectives, New NCCN Guidelines, and Other Updates in Cancer Care

23rd NCCN Annual Conference: Improving the Quality, Effectiveness, and Efficiency of Cancer Care will take place March 22 – 24, 2018, in Orlando, Florida, and address value-based healthcare models, payer perspectives, new NCCN Guidelines, and other...

– National Comprehensive Cancer Network® (NCCN®)

Henry Ford Health System to Set New Standard for Patient Care Utilizing accesso’s Newest Technology, The Experience Engine (TE2)

accesso, the premier technology solutions provider to leisure, entertainment, cultural and hospitality markets has chosen Henry Ford Health System as its first ever healthcare partner.

– Henry Ford Health System

Virus-Like Particle Could Lead to New Cancer Vaccine

Michigan State University scientists are engineering a virus-like particle, known as Qβ, that will generate anti-cancer immune responses in the body and potentially be used as a new vaccine for the treatment of cancer.

– Michigan State University

Jack Martin Fund Provides Transformational Gift to Open Mount Sinai Inpatient Unit for Children’s Cancer and Blood Disease

Newly named unit is located within the Division of Pediatric Hematology-Oncology at Kravis Children’s Hospital at Mount Sinai

– Mount Sinai Health System

Frederick National Laboratory for Cancer Research and Georgetown University Launch Research, Education Collaboration

A new collaboration established between Georgetown University and the Frederick National Laboratory for Cancer Research aims to expand both institutions’ research and training missions in the biomedical sciences.

– Georgetown University Medical Center

Higher Education Events

Motorcyclists to Raise Money and Awareness for Cancer Research in NM

The annual ‘Ride for the Cure NM’ motorcycle ride raises money and awareness for cancer research and treatment in New Mexico. Every dollar the raised through the ride is donated to The University of New Mexico Comprehensive Cancer Center. Last ye...

– University of New Mexico Comprehensive Cancer Center





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