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Newswise Special Wire
Tuesday, March 13, 2018

Public edition |

Newswise Cancer Research Wire for 13-Mar-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Surprising Discovery Provides Insights Into Aggressive Endometrial Cancers

New research from Huntsman Cancer Institute (HCI) at the University of Utah (U of U) indicates steroid and hormone receptors are simultaneously active in many endometrial cancer tissues. The findings, published today in the journal Cell Reports, yiel...

– Huntsman Cancer Institute at the University of Utah

Cell Reports; P30 CA042014

Embargo expired on 13-Mar-2018 at 12:00 ET

Engineers Develop Most Efficient Red-Light-Activated Switch That Can Turn Genes on and Off in Mammalian Cells

A team of researchers has developed a light-activated switch that can turn genes on and off in mammalian cells. This is the most efficient so-called “optogenetic switch” activated by red and far-red light that has been successfully designed and t...

– University of California San Diego

ACS Synthetic Biology

Embargo expired on 13-Mar-2018 at 08:00 ET

Testicular Cancer Survivors Need Adequate Screening for Long Term Heart Disease Risks

Largest study to date addressing the prevalence of metabolic abnormalities in testicular cancer survivors who received prior chemotherapy publishes findings in the latest issue of JNCCN

– National Comprehensive Cancer Network® (NCCN®)

JNCCN –Journal of the National Comprehensive Cancer Network

Release of the Cancer Incidence and Survival Statistics for Northern Ireland 2012-2016

The Queen’s University N. Ireland Cancer Registry (NICR) today released the number of new cancer cases diagnosed (incidence) in Northern Ireland in 2016. Legislation designating the Northern Ireland Cancer Registry (NICR) as an official producer of...

– Queen's University Belfast

Mayo Clinic的临床试验匹配项目显示,使用人工智能会使更多患者参与乳腺癌试验


– Mayo Clinic

New iPad App Could Improve Colon Cancer Screening Rates

Say ordering a cancer screening test was as easy as booking a hotel room online. Would that improve screening rates?

– Wake Forest Baptist Medical Center

Annals of Internal Medicine, early online, March - 2018

Embargo expired on 12-Mar-2018 at 17:00 ET

Some Breast Cancer Patients Are Missing Out on Genetic Counseling

Nearly half of newly diagnosed breast cancer patients who should be recommended for genetic testing did not get it. A quarter of these patients were not counseled about their potential risk, a new study finds.

– Michigan Medicine - University of Michigan

Journal of Clinical Oncology; CA163233; P30CA46592

Embargo expired on 12-Mar-2018 at 16:00 ET

ASTRO Issues Clinical Guideline for Whole Breast Radiation Therapy

The American Society for Radiation Oncology (ASTRO) today issued a new clinical guideline for the use of whole breast radiation therapy for breast cancer that expands the population of patients recommended to receive accelerated treatment known as hy...

– American Society for Radiation Oncology (ASTRO)

Practical Radiation Oncology, Mar-2018

Embargo expired on 12-Mar-2018 at 17:00 ET

Poorer Socioeconomic Status Predicts Lower Survival in Patients with Anal Cancer

If you are from a lower income area, your chances of surviving anal cancer are significantly reduced, according to a new study.

– NYU Langone Health


Polymer Nanoparticle Shows Ability to Locate and Treat Breast Tumors

One major problem in treating cancer is identifying the location of small tumors and treating them before they metastasize.

– Wake Forest Baptist Medical Center

ACS Applied Materials and Interfaces, March-2018

News From Molecular & Cellular Proteomics

Research Highlights: a proteomics study to understand a rare skin disease; understanding T cell activation through "click chemistry."

– American Society for Biochemistry and Molecular Biology (ASBMB)

Molecular & Cellular Proteomic; Molecular & Cellular Proteomic

Southern Research Targets Mutated Protein to Battle Prostate Cancer

Southern Research scientists are exploring how a mutated protein implicated in prostate cancer plays a role in the development of the disease and whether it holds a key to better treatment outcomes.

– Southern Research

Study: Two Drugs Prevent Heart Problems in Breast Cancer Patients

Data presented from a Late-Breaking Clinical Trial has the potential to change the standard of care for HER2-positive breast cancer patients undergoing chemotherapy.

– University of Kentucky

American College of Cardiologists Scientific Session; NCIT01009918

Embargo expired on 11-Mar-2018 at 00:00 ET

New Targeted Therapeutic Approach to Combat Ovarian Cancer

According to a new study by The Wistar Institute, EZH2 inhibitors that are currently in clinical development for hematological malignancies and solid tumors may be effectively targeted to epithelial ovarian cancers overexpressing the CARM1 protein. ...

– Wistar Institute

Nature Communications

Liquid Biopsy Tests in People with Cancer: An Expert Review More Evidence Needed to Establish Effective and Appropriate Use in the Clinic

Use of tests that assess genomic variants in circulating tumor DNA (ctDNA) is on the rise. A new joint review from the American Society of Clinical Oncology (ASCO) and the College of American Pathologists (CAP) provides an assessment of evidence on c...

– College of American Pathologists (CAP)


Virtual Reality: An Escape From Painful and Stressful Medical Treatments

VR has shown promise in several clinical trials assessing its possible utility as a distraction tool to alleviate pain and distress during medical procedures.

– Sbarro Health Research Organization (SHRO)

The Clinical Journal of Pain

Colorectal Cancer: Routine Colonoscopies and Early Detection Can Save Your Life

Having a colonoscopy to screen for colorectal cancer is not on anyone’s list of favorite activities. However, with colorectal cancer ranking as the second leading cause of cancer death in the United States, undergoing the outpatient procedure as pe...

– Valley Health System

Barriers to the Diagnosis & Treatment of Colorectal Cancer: Patients Speak Out

In a study published in the April issue of Diseases of the Colon & Rectum, researchers present results of a study designed to identify factors associated with disparities in colorectal cancer care. They studied a group of 30 primary minority, lower i...

– Diseases of the Colon and Rectum Journal

Dis Colon Rectum 2018;61:504-513

Embargo expired on 08-Mar-2018 at 13:00 ET

Mayo Clinic’s Clinical Trial Matching Project Sees Higher Enrollment in Breast Cancer Trials Through Use of Artificial Intelligence

Mayo Clinic and IBM Watson Health today unveiled results from early use of the Watson for Clinical Trial Matching, an IBM cognitive computing system. Use of this system in the Mayo Clinic oncology practice has been associated with more patients enrol...

– Mayo Clinic

Breast Cancer Care in U.S. Territories Lags Behind Care in States

Older women residing in the U.S territories are less likely to receive recommended or timely care for breast cancer compared with similar women residing in the continental United States, according to Yale researchers.

– Yale Cancer Center

News From the Journal of Lipid Research

A lotion inspired by babies’ skin, membrane binding by an inflammation-linked kinase, and a colorectal cancer-fighting microRNA.

– American Society for Biochemistry and Molecular Biology (ASBMB)

Journal of Lipid Research; Journal of Lipid Research; Journal of Lipid Research

Thirdhand Smoke Found to Increase Lung Cancer Risk in Mice

Researchers at Berkeley Lab identified thirdhand smoke, the toxic residues that linger on indoor surfaces and in dust long after a cigarette has been extinguished, as a health hazard nearly 10 years ago. Now a new study has found that it also increas...

– Lawrence Berkeley National Laboratory

Clinical Science; Release online

Acute Myeloid Leukemia Patients Have Reduced Early Mortality at NCI-Designated Cancer Centers

Researchers at UC Davis have shown that patients with acute myeloid leukemia (AML) who received their care at a National Cancer Institute (NCI) cancer center in California had a dramatically reduced risk of early mortality. Using data from the Califo...

– UC Davis Comprehensive Cancer Center


Never Smokers: The New Face of Lung Cancer

“Did you smoke?” Few questions engender such anger and annoyance in patients as that one, particularly in the 10%-20% of lung cancer patients who are “never smokers.” Read “Never Smokers: The New Face of Lung Cancer”—the latest blog fro...

– The Society of Thoracic Surgeons

ASU Students Develop at-Home Pap Smear Test

Industrial design students use ingenuity to create more effective vision of future of women’s health care; product heads to national show

– Arizona State University (ASU)

Debunking 6 Misconceptions About Colorectal Cancer

It’s the second-most common cancer killer in the U.S., but misconceptions about colorectal cancer can keep people from accessing the preventive care and treatment they might need. Fred Hutchinson Cancer Research Center experts address some of the m...

– Fred Hutchinson Cancer Research Center

Fred Hutch

Epigenomic Tool Breakthrough Has Implications for Identifying Disease Processes

A major advancement has been made on how epigenomics are studied that permits mapping a genome-scale profile of epigenetic changes using less than a couple hundred of cells, a factor of 100-300 reduction in the sample amount compared to existing alte...

– Virginia Tech


Embargo expired on 07-Mar-2018 at 11:00 ET

MRI Can Help Detect Prostate Cancer, Reduce Unnecessary Biopsies

In a collaborative, multi-institutional study published by JAMA Oncology, researchers from the University of Alabama at Birmingham, University of Chicago, and National Cancer Institute determined that MRI-based prediction models can help reduce unnec...

– University of Alabama at Birmingham

JAMA Oncology

Roswell Park Familial Ovarian Cancer Registry Data Link Ovarian and Testicular Cancer

Using data from a large ovarian cancer registry, a research team from Roswell Park Comprehensive Cancer Center uncovered a link between testicular cancer and familial ovarian cancer that may be attributable to genetic factors on the X chromosome.

– Roswell Park Comprehensive Cancer Center

Cancer Epidemiology, Cancer Epidemiology Volume 53, April 2018, Pages 184–186

Treating Hypothyroidism to Stop a Stubborn Surgical Complication

For the first time, researchers have linked radiation-damaged thyroid glands to poor surgical outcomes. The solution may be as simple as a common hormone supplement. Researchers at the University of Michigan have discovered a link between low thyroid...

– Michigan Medicine - University of Michigan

Annals of Surgical Oncology

Policy and Public Affairs

Colorectal Cancer Patients to Congress: Help Save Lives!

Fight Colorectal Cancer's 12th annual Call-on Congress will bring over 150 advocates to D.C - the largest group yet

– Fight Colorectal Cancer


Schedule Announced for Nutrition 2018 Meeting

Nutrition 2018, to be held June 9-12, 2018 at the Hynes Convention Center in Boston, will feature new research findings and panel discussions addressing hot topics in clinical practice and policy.

– American Society for Nutrition (ASN)

Seattle Cancer Care Alliance Medical Director F. Marc Stewart, MD Earns Outstanding Medical Director Award

Seattle Cancer Care Alliance Medical Director F. Marc Stewart, MD received a silver “Outstanding Medical Director” award from Seattle Business magazine. The award was presented at the magazine’s ninth annual Leaders in Health Care Awards event,...

– Seattle Cancer Care Alliance

UTSW Teams with Allen Americans for Americans Fight Cancer Weekend

The Allen Americans are proud to partner with the only National Cancer Institute designated Comprehensive Cancer Center in North Texas, UT Southwestern Harold C. Simmons Comprehensive Cancer Center for Americans Fight Cancer Weekend April 6th and 7th...

– UT Southwestern Medical Center

Dana-Farber’s Bank of Patient-Derived Tumor Xenografts Gets Major Boost From Novartis

Dana-Farber Cancer Institute is establishing a bank of patient-derived xenograft models of more than 750 human tumors.

– Dana-Farber Cancer Institute

MD Anderson and Berkeley Lights Launch Optera Therapeutics to Accelerate Development of Cell Therapies for Cancer

The University of Texas MD Anderson Cancer Center and Berkeley Lights, Inc. today announced the launch of Optera Therapeutics Corp, a biopharmaceutical company developing cell therapies with scalable manufacturing solutions for cancer.

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 07-Mar-2018 at 07:30 ET

Edward M. Wolin, MD, Appointed Director of the Center for Carcinoid and Neuroendocrine Tumors at The Tisch Cancer Institute

Edward M. Wolin, MD, an internationally renowned authority on neuroendocrine tumors—a type of rare but increasingly frequently diagnosed cancer—has joined the Mount Sinai Health System as Director of the Center for Carcinoid and Neuroendocrine Tu...

– Mount Sinai Health System

The Healthy Scratch Opens on Roswell Park Campus

The second location of The Healthy Scratch opened on Roswell Park’s campus. The grab-and-go café provides patients, visitors and employees with a new option for clean eating – and for foods and juices that may help to keep cancer at bay.

– Roswell Park Comprehensive Cancer Center

Roswell Park Approved to Administer CAR T-Cell Therapy, Yescarta, to Lymphoma Patients

Roswell Park Comprehensive Cancer Center has been officially approved to administer an FDA-approved CAR T-cell therapy, Yescarta, to lymphoma patients.

– Roswell Park Comprehensive Cancer Center


Students Innovate DIY Pap Smear Test, App

ASU students design user-friendly pap smear kit, win top prize

– Arizona State University (ASU)

Expert Pitch

Yale Expert Available to Speak on Medical Marijuana for Children with Cancer

– Yale Cancer Center


Yale Expert to Speak on PD-L1 Biomarkers in the Treatment of Bladder Cancer

Dr. Petrylak, Professor of Medicine (Medical Oncology) and of Urology; Co-Director, Signal Transduction Research Program, Yale Cancer Center, considers whether PD-L1 biomarkers are useful in the treatment of bladder cancer.

– Yale Cancer Center





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