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Newswise Special Wire
Tuesday, April 24, 2018

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Newswise Cancer Research Wire for 24-Apr-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

How Colorectal Cancer Cells Spread to the Liver

A new study by Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers helps explain the connection between a tumor suppressor called protein kinase C zeta (PKC zeta) and metastatic colorectal cancer.

– Sanford Burnham Prebys Medical Discovery Institute

Cell Reports; R01DK108743; R01CA172025; R01CA207177; R01CA192642; R01CA218254

Embargo expired on 24-Apr-2018 at 12:00 ET

Five Ways to Help Cancer Patients Avoid the Emergency Room

Unnecessary emergency department visits and hospitalizations are debilitating for patients with cancer and far too common – and costly – for the United States health care system. To reverse the trend, researchers at the Abramson Cancer Center, th...

– Perelman School of Medicine at the University of Pennsylvania

Journal of Oncology Practice

Drinking Affects Mouth Bacteria Linked to Diseases

When compared with nondrinkers, men and women who had one or more alcoholic drinks per day had an overabundance of oral bacteria linked to gum disease, some cancers, and heart disease. By contrast, drinkers had fewer bacteria known to check the growt...

– NYU Langone Health


Embargo expired on 23-Apr-2018 at 20:00 ET

Size, Structure Help Poziotinib Pose Threat to Deadly Exon 20 Lung Cancer

A drug that failed to effectively strike larger targets in lung cancer hits a bulls-eye on the smaller target presented by a previously untreatable form of the disease, researchers at The University of Texas MD Anderson Cancer Center report in Nature...

– University of Texas M. D. Anderson Cancer Center

Nature Medicine

Embargo expired on 23-Apr-2018 at 11:00 ET

CHIPing Away at Cancer Tumors Through Genomic Analysis

Investigators at Rutgers Cancer Institute have discovered that some mutations detected in comprehensive, clinical genome sequencing of patients with solid tumors do not originate from cancer cells, but arise from mutated hematopoietic cells that infi...

– Rutgers Cancer Institute of New Jersey

Blood, April-2018

Cigarillo Packaging Can Influence Product Perception, Study Finds

UNC Lineberger Comprehensive Cancer Center researchers surveyed 2,664 young adults who were current users, never users, or past users of little cigars and cigarillos, finding cigarillo packs with colors and containing a flavor descriptor were rated m...

– University of North Carolina Health Care System


Nurses Develop Standardized Checklist to Better Educate Parents of Children Newly Diagnosed with Cancer

Chicago (April 23, 2018) - Parents and others who care for children newly diagnosed with cancer must learn a wealth of new information to safely do so at home, and it is a core responsibility of pediatric oncology nurses to educate them, often based ...

– Association of Pediatric Hematology/Oncology Nurses (APHON)

Journal of Pediatric Oncology Nursing

Scientists Create Better Laboratory Tools to Study Cancer’s Spread

In the journal Nature Biomedical Engineering, UNC Lineberger Comprehensive Cancer Center researchers and colleagues report they have developed tissue-engineered models for cancer metastases that reflect the microenvironment around tumors that promote...

– University of North Carolina Health Care System

Nature Biomedical Engineering

NUS study: ‘Genomic junk’ of iron storage gene FTH1 critical for suppressing prostate cancer growth

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have found the role of the iron storage gene, FTH1, and its pseudogenes in regulating iron levels in cells and slowing down prostate ca...

– National University of Singapore

Nucleic Acids Research

Orlando Health UF Health Cancer Center First to Dose Patient in New Breast Cancer Study

Orlando Health UF Health Cancer Center is the first to dose a patient in a study for an experimental drug to treat metastatic breast cancer in post-menopausal women.

– Orlando Health

PTSD Therapies, Safety Measures in Low-Income Countries, Race and Opioids, and More in the Public Health News Source

The latest research, experts and features in Public Health in the Public Health News Source

– Newswise

First-Ever Study of Triple Gene Combinations Could Help Predict Risk of Disease

In the largest study of its kind, researchers at the University of Minnesota and University of Toronto have revealed a complex network of genes that work together. Understanding those genetic connections can help develop new life-saving treatments t...

– University of Minnesota College of Science and Engineering

Science, April 20, 2018

Gene Editing on a Chip: Researchers Use CRISPR to Edit DNA Outside of the Cell for the First Time

Scientists at Christiana Care Health System’s Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and ...

– Christiana Care Health System

CRISPR Journal, April 19, 2018

Embargo expired on 19-Apr-2018 at 10:00 ET

Study May Explain Why Some Triple-Negative Breast Cancers Are Resistant to Chemotherapy

Triple-negative breast cancer (TNBC) is an aggressive form of the disease accounting for 12 to 18 percent of breast cancers. It is a scary diagnosis, and even though chemotherapy can be effective as standard-of-care, many patients become resistant to...

– University of Texas M. D. Anderson Cancer Center


Embargo expired on 19-Apr-2018 at 12:00 ET

Chip-Based Blood Test for Multiple Myeloma Could Help Make Bone Biopsies a Relic of the Past

A new University of Kansas research effort featured in the current edition of Integrative Biology has resulted in a low-cost, reliable blood test that uses a small plastic chip about the size of a credit card that can deliver the same diagnostic info...

– University of Kansas Cancer Center

Integrative Biology

Drug Combination Targeting Heat Shock Protein 90 and BRAF is Safe and Effective in Advanced Melanoma Patients

TAMPA, Fla. – Patients with advanced or metastatic melanoma have been able to live longer cancer-free lives because of several new therapies approved over the last decade, such as BRAF and MEK inhibitors. However, despite the success of these targe...

– Moffitt Cancer Center

Clinical Cancer Research

Scientists Identify 170 Potential Lung Cancer Drug Targets Using Unique Cellular Library

After testing more than 200,000 chemical compounds, UT Southwestern’s Simmons Cancer Center researchers have identified 170 chemicals that are potential candidates for development into drug therapies for lung cancer.

– UT Southwestern Medical Center


This Remote-Control Shoots Laser at Gold to Switch on Cancer-Killing Immune Cells

Cancer immune cell therapy has made headlines with astounding successes like saving former U.S. President Jimmy Carter from brain cancer. But immunotherapy has also had many tragic flops. Georgia Tech researchers working to optimize the innovative tr...

– Georgia Institute of Technology

ACS Synthetic Biology; DP2HD091793; UL1TR000454; 5T32EB006343; DGE-1451512

Indoor Tanners: Are they taking Steps to Protect against Skin Cancer?

Are indoor tanners taking measures to prevent skin cancer? A researcher from Rutgers Cancer Institute of New Jersey and colleagues at Fox Chase Cancer Center found a majority of the indoor tanners analyzed in this study are not taking part in skin ca...

– Rutgers Cancer Institute of New Jersey

JAMA Dermatology, April 2018

UNMC, Genomoncology Combine to Launch First System Using HL7 2.5 Formatting to Transmit Discrete Genetic Data on Cancer Patients to Electronic Health Record

Breakthrough streamlines patient information into a manageable, digestible format, so oncologists can view discrete genetic data in the patient 's electronic health record

– University of Nebraska Medical Center (UNMC)

Roswell Park Researchers Identify Epigenetic Changes that May Help Explain Racial Disparities in Breast Cancer

Roswell Park Comprehensive Cancer Center researchers have identified epigenetic differences in the breast cancer tumors of African-American women and women of European descent, shedding light on one mechanism by which race may influence the way breas...

– Roswell Park Comprehensive Cancer Center

AACR Annual Meeting 2018

Sedentary Lifestyle Drastically Increases Risk of Dying from Cancer

Roswell Park Comprehensive Cancer Center researchers have once again identified a link between physical inactivity and an increased risk of mortality among cancer patients, emphasizing the importance of regular exercise as therapy for cancer patient...

– Roswell Park Comprehensive Cancer Center

AACR Annual Meeting 2018

Researchers Identified a Protein Associated with Breast Cancer

Researchers at UT Southwestern Medical Center have identified a protein that is strongly associated with metastatic breast cancer and that could be a target for future therapies.

– UT Southwestern Medical Center

Journal of Clinical Investigation

New Drugs Using the Body’s Natural “Marijuana” Could Help Treat Pain, Cancer

A new technology developed by Stony Brook University researchers affiliated with the Institute of Chemical Biology and Drug Discovery (ICB & DD) that has identified Fatty Acid Binding Proteins (FABPs) as drug targets of the body’s endocannabinoid s...

– Stony Brook Medicine

Novel Proteomics Strategies Aid Cancer Research

This month’s issue of the journal Molecular & Cellular Proteomics features research using novel proteomics methods to address unanswered questions in cancer research, including protein variation within tumors; the failure of a candidate cancer drug...

– American Society for Biochemistry and Molecular Biology (ASBMB)

Molecular & Cellular Proteomics; Molecular & Cellular Proteomics; Molecular & Cellular Proteomics

Man's Heartbeat Continues to Beat After Death with Help of Music Therapy Project

Steven Eaise was 47 years old when he was diagnosed with colon cancer in 2015. Today, a unique part of him lives on thanks to a music therapy project. Music therapists at UAB recorded Steven’s heartbeat, then incorporated it into a song, using his ...

– University of Alabama at Birmingham


Columbia University School of Nursing Launches Comprehensive Palliative Care Program for Students at All Levels

Columbia University School of Nursing is launching a school-wide palliative care education program that integrates the basic principles of palliative care into the curriculum for nursing students at all levels. The program reflects the recent develop...

– Columbia University Irving Medical Center

Penn Medicine’s Carl June, MD, Named One of Time Magazine’s Most Influential People in the World

TIME named University of Pennsylvania cancer and HIV gene therapy pioneer Carl June, MD, to the 2018 TIME 100, its annual list of the 100 most influential people in the world.

– Perelman School of Medicine at the University of Pennsylvania

$2 Million Grant to Push Forward Cancer Research in West Texas

A $2 million grant from the Cancer Prevention and Research Institute of Texas (CPRIT) will allow Texas Tech University Health Sciences Center El Paso (TTUHSC El Paso) to create a new lab focusing on breast cancer, pushing forward breast cancer resear...

– Texas Tech University Health Sciences Center El Paso

American Academy of Dermatology Awards 26 Shade Structure Grants to Protect America’s Youth

Skin cancer is the most common cancer in the United States, and it only takes one blistering sunburn during childhood or adolescence to nearly double a person’s chance of developing melanoma, the deadliest form of skin cancer, later in life. To hel...

– American Academy of Dermatology

Mount Sinai Health System Expands Innovative Cancer Care in Brooklyn

The Mount Sinai Health System today opened the Mount Sinai Brooklyn Ambulatory Infusion Center, a new cancer treatment center that will bring Mount Sinai’s innovative cancer treatment and clinical trials to residents of southern Brooklyn.

– Mount Sinai Health System

CHOP’s Breakthrough Cancer Immunotherapy Program Receives Generous Grant from The Emily Whitehead Foundation

The Emily Whitehead Foundation today presented a check totaling $250,000 to Stephan A. Grupp, MD, PhD, Director of the Cancer Immunotherapy Frontier Program, and Section Chief of the Cellular Therapy and Transplant Program at Children’s Hospital of...

– Children's Hospital of Philadelphia

Embargo expired on 17-Apr-2018 at 15:00 ET





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