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Newswise Special Wire
Tuesday, May 29, 2018

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Newswise Cancer Research Wire for 29-May-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Single Injection Alleviates Chemotherapy Pain for Months in Mice

UC San Diego School of Medicine researchers found that treating mice with a single spinal injection of a protein called AIBP — and thus switching “off” TLR4, a pro-inflammatory molecule — prevented and reversed inflammation and cellular event...

– University of California San Diego Health

Cell Reports

Embargo expired on 29-May-2018 at 11:00 ET

Immunotherapy Clinical Trial Reveals Brain Tumor Shrinkage, Continues with Phase 3 Study

Following successful Phase 1 clinical trials, the Toca regimen – a new immunotherapy for patients with recurrent brain cancer – has advanced to a Phase 3 study, which is currently underway. The trial is being conducted at 68 sites across the Unit...

– Atlantic Health System

To Scan or Not to Scan: Research Shows How to Personalize Lung Cancer Screening Decisions

A new study shows how to personalize lung cancer CT screening decisions, so doctors can fine-tune their advice to patients based not just on individual lung cancer risk and the potential benefits and harms of screening, but also a likely range of pat...

– Michigan Medicine - University of Michigan

Annals of Internal Medicine, doi:10.7326/M17-2561

Embargo expired on 28-May-2018 at 17:00 ET

Genome’s Dark Matter Offers Clues to Major Challenge in Prostate Cancer

Researchers at the University of Michigan Rogel Cancer Center identified a novel gene they named ARLNC1 that controls signals from the androgen receptor, a key player in prostate cancer. Knocking down this long non-coding RNA in mice led to cancer ce...

– Michigan Medicine - University of Michigan

Nature Genetics; P50CA186786; CA214170; DP5 OD012160

Embargo expired on 28-May-2018 at 11:00 ET

By Forming Clots in Tumors, Immune Cell Aids Lung Cancer's Spread

In the journal Nature Communications, researchers report for a particular subset of lung cancer tumors, there is a high prevalence of immune cells called inflammatory monocytes. These immune cells, which normally help to build clotting scaffolds to p...

– University of North Carolina Health Care System

Nature Communications

New Report on the Global Landscape of Cancer Cell Therapy Highlights Robust International Pipeline Marked by Rapid Growth

Newly published report in Nature Reviews Drug Discovery that provides a comprehensive, independent analysis of the global landscape of cancer cell therapies, including all agents from preclinical to post-market stages.

– Cancer Research Institute

Tang J. et al. Global landscape of cancer cell therapy. Nature Reviews Drug Discovery. 25 May 2018. doi:10.1038/nrd.2018.74

Cancer Cells Co-Opt Pain-Sensing ‘Wasabi Receptor’ to Survive Oxidative Stress

Some cancers express unusually high levels of a neural calcium channel known as the ‘wasabi receptor,’ which plays a role in detecting pain, cold and other sensations. New research finds cancer cells co-opt this neural channel to increase their t...

– Harvard Medical School

Cancer Cell

Embargo expired on 24-May-2018 at 11:00 ET

A System of Check and Balances in the Blood

Hematopoietic Stem Cells (HSCs) give rise to blood and immune cells of the body, and are therefore essential for our survival. They are in a dormant state, but whenever new blood needs to be formed, such as after blood loss or chemotherapy, they are ...

– University of Vienna

Cell Stem Cell

Embargo expired on 24-May-2018 at 11:00 ET

St. Jude Children’s Research Hospital Expands International Reach with St. Jude Global

Hospital invests more than $100 million in unique initiative aimed at accelerating efforts to improve childhood cancer survival rates worldwide

– St. Jude Children's Research Hospital

Embargo expired on 24-May-2018 at 14:30 ET

Breast Cancer Survivors Aren’t Getting Recommended Number of Mammograms Post-Surgery, Study Finds

A new study in JNCCN finds that, contrary to screening recommendations, mammography rates decline over time as women get further out from their breast cancer diagnosis; African-American women in particular were less likely to receive the recommended ...

– National Comprehensive Cancer Network® (NCCN®)

Journal of the National Comprehensive Cancer Network

Fred Hutch Scientists to Feature Health Economics, Next-Gen Immunotherapy, Health Disparities and More at ASCO

Fred Hutchinson Cancer Research Center’s latest findings will be featured at the annual meeting of the American Society of Clinical Oncology, “Delivering Discoveries: Expanding the Reach of Precision Medicine,” to be held June 1–5 in Chicago....

– Fred Hutchinson Cancer Research Center

New Jersey Health Care Providers, Community Members, and Researchers Come together to Address Disparities and Improve Screening Opportunities for Colorectal and Lung Cancers

Health care providers, community members, and researchers from across New Jersey came together at the ‘Conference for Change’ event, hosted by the New Jersey Primary Care Association and sponsored by ScreenNJ to address the need to improve screen...

– Rutgers Cancer Institute of New Jersey


Sun Safety: Planning is Your Best Protection

Longer days means more exposure to the sun and harmful UV rays. A Rutgers Cancer Institute of New Jersey expert shares some tips on how to keep your skin safe this season and all year long.

Expert Available

– Rutgers Cancer Institute of New Jersey

New Paper Highlights Role of Immune-Stimulating Cells that Shrink Breast Cancer Tumors

Targeted cancer immunotherapy with irradiated, granulocyte–macrophage colony-stimulating factor (GM-CSF)-secreting, allogeneic cancer cell lines has been an effective approach to reduce tumor burden in several patients. A new paper in the Frontiers...

– BriaCell Therapeutics Corp

Frontiers in Immunology

Rapamycin Lotion Reduces Facial Tumors Caused by Tuberous Sclerosis, UTHealth Reports

Addressing a critical issue for people with a genetic disorder called tuberous sclerosis complex (TSC), doctors at The University of Texas Health Science Center at Houston (UTHealth) reported that a skin cream containing rapamycin significantly reduc...

– University of Texas Health Science Center at Houston

JAMA Dermatology

How a Cell Knows When To Divide

How does a cell know when to divide? We know that hundreds of genes contribute to a wave of activity linked to cell division, but to generate that wave new research shows that cells must first grow large enough to produce four key proteins in adequat...

– Rensselaer Polytechnic Institute (RPI)

Cell Systems

Real-Time Proteomics May One Day Speed Up Cancer Surgery

French researchers have developed a device that painlessly ionizes the top few microns of skin for analysis by mass spectrometry. The device is being tested to make surgery more efficient in pet dogs with sarcoma.

– American Society for Biochemistry and Molecular Biology (ASBMB)

Molecular & Cellular Proteomics

Israeli and American Researchers Have Successfully Curbed Mesothelioma in Model Animals

A team led by researchers from the Technion and NYU Langone has successfully impeded the development of mesothelioma - a disease for which there is currently no effective treatment. Mesothelioma, a cancer that develops in the thin membrane that prote...

– American Technion Society

Journal of the National Cancer Institute, Mar 21-2018

Rusk Rehabilitation Launches Specialized Program to Optimize Quality of Life in Cancer Survivors

Rusk Rehabilitation at NYU Langone Health has opened a new specialized program to address the complex rehabilitative needs of individuals with cancer, with a principal goal of helping them re-establish optimal function during and following treatment....

Expert Available

– NYU Langone Health

A descoberta da Mayo ajuda os médicos a personalizar o tratamento de pacientes com câncer no ovário e no cérebro.

Os pesquisadores da Mayo Clinic descobriram que uma via de comunicação molecular – considerada ser deficiente em câncer – é um fator chave na determinação da eficácia do tratamento de câncer oncolítico do virus do sarampo em cânceres do...

– Mayo Clinic

Journal of the National Cancer Institute


UCI Center on Stress & Health awarded $6.3 million by National Institutes of Health

Researchers at the University of California, Irvine’s Center on Stress & Health have received $6.3 million in grants from the National Institutes of Health to develop and test digital health interventions for stress and pain in children facing surg...

– University of California, Irvine

Top Cancer Clinician-Scientist Appointed Director of Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai

Renowned cancer clinician and scientist Dan Theodorescu, MD, PhD, has been named director of the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai.

– Cedars-Sinai

Seattle Cancer Care Alliance Receives National Employer of Excellence Award

Seattle Cancer Care Alliance (SCCA) is one of eight national recipients of an Employer of Excellence award from the American Academy of Physician Assistants (PA’s) Center for Healthcare Leadership and Management.

– Seattle Cancer Care Alliance

New Grant Funds Cutting-Edge UCLA Clinical Trial for Late-Stage Lung Cancer

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA a have been awarded a $12M grant from the California Institute for Regenerative Medicine – also known as CIRM – to initiate a phase 1 clinical ...

– University of California, Los Angeles (UCLA), Health Sciences

WCG Foundation Is Now Clinical Research Pathways

Name change for WCG Foundation

– Clinical Research Pathways

Penn State Health and Andrews Patel Hematology/Oncology Reach Agreement

Penn State Health and Andrews Patel Hematology/Oncology announced today they have reached agreement to join together to provide unmatched, patient-focused oncology and hematology services to central Pennsylvania and the surrounding region.

– Penn State Health Milton S. Hershey Medical Center

The Gene Editing Institute of Christiana Care Receives First-Ever Life Sciences and Bio Innovation Award from Philadelphia-Israeli Chamber of Commerce

For ground-breaking scientific research in gene editing and an innovative partnership with Jerusalem-based NovellusDx to advance personalized cancer treatment, the Gene Editing Institute of the Helen F. Graham Cancer Center & Research Institute at Ch...

– Christiana Care Health System

U-M Rogel Cancer Center First in Michigan to Offer All FDA Approved Car T-Cell Therapies

With the recently announced FDA approval of Kymriah to treat adults with lymphoma, the University of Michigan Rogel Cancer Center is the first center in Michigan to offer all currently available CAR T-cell therapies.

– Michigan Medicine - University of Michigan

Higher Education Events

Two Nashville Events to Raise Funds for Fight Colorectal Cancer This June

Country music artist Craig Campbell is hosting his annual celebrity cornhole challenge and co-hosting the annual benefit dinner

– Fight Colorectal Cancer

Expert Pitch

UT Southwestern Leads Expert Consortium Refining Prognosis of Invasive Kidney Cancer

– UT Southwestern Medical Center





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