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Newswise Special Wire
Tuesday, July 31, 2018

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Newswise Cancer Research Wire for 31-Jul-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Turning Off Protein Could Boost Immunotherapy Effectiveness on Cancer Tumors

Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy in the Johns Hopkins Kimmel Cancer Center discovered inhibiting a previously known protein could reduce tumor burdens and enhance the effectiveness of immunotherapy treatments.

– Johns Hopkins Medicine

Cancer Discovery; 81571564, 81521004, 81522020

Therapy for Rare Cancers Receives FDA Approval Following Trials at Penn’s Abramson Cancer

The U.S. Food and Drug Administration (FDA) has approved the first ever non-surgical treatment for the rare neuroendocrine cancers pheochromocytoma and paraganglioma. The approval was based on a multi-center trial led by researchers in the Abramson C...

– Perelman School of Medicine at the University of Pennsylvania

Scientists Discover a Dynamic Cellular Defense Against Breast Cancer Invasion

Johns Hopkins researchers report they have demonstrated in mouse tissue grown in the lab that the cell layer surrounding breast milk ducts reaches out to grab stray cancer cells to keep them from spreading through the body. The findings reveal that t...

– Johns Hopkins Medicine

Journal of Cell Biology

Embargo expired on 30-Jul-2018 at 09:00 ET

Do Obese Patients Have a Higher Risk of Infection and Dying After Colon Surgery?

In a study published in the August issue of Diseases of the Colon & Rectum, investigators from the University of Alabama at Birmingham sought to answer this question. While it has been long recognized that heavy patients are at higher risk of complic...

– Diseases of the Colon and Rectum Journal

Dis Colon Rectum 2018;61:938-945

What Is Important to Patients Undergoing Colorectal Surgery?

What do patients really want? These are Important questions that doctors at the University of Vermont have tried to answer. In the August issue of Diseases of the Colon & Rectum, Dr. Wrenn and his colleagues surveyed 167 patients who had undergone a ...

– Diseases of the Colon and Rectum Journal

Dis Colon Rectum 2018;61;(8):971-978

Ivosidenib earns FDA approval against IDH1+ acute myeloid leukemia

Clinical trials at CU Cancer Center and elsewhere result in FDA approval of the drug ivosidenib for the treatment of adult patients with IDH1+ AML.

– University of Colorado Cancer Center

Magnetic Nanoparticles Deliver Chemotherapy to Difficult-to-Reach Spinal Tumors

Researchers at the University of Illinois at Chicago have demonstrated that magnetic nanoparticles can be used to ferry chemotherapy drugs into the spinal cord to treat hard-to-reach spinal tumors in an animal model. The unique delivery system repres...

– University of Illinois at Chicago

Scientific Reports

Harnessing Hair Loss Gene Could Improve Cancer Immunotherapy

Researchers at Columbia found that a gene associated with an autoimmune form of hair loss may be activated to boost cancer immunotherapy.

– Columbia University Irving Medical Center

Cell Systems

IU Research on Mutation 'Hotspots' in DNA Could Lead to New Insights on Cancer Risks

New research from Indiana University has identified "hotspots" in DNA where the risk for genetic mutations from errors during cellular replication is significantly elevated. The results are significant since DNA errors play a significant role in many...

– Indiana University

Genetics; Genetics; T32 GM007757; W911NF-09- 1-0444

WVU Researchers Working to Stop Cancer-Growth Protein

What do one in five breast cancers have in common? Large amounts of a protein called HER2 (or human epidermal growth factor receptor 2). “Every healthy cell produces a normal amount of HER2, but HER2 is produced 10 to 20 times more in a cancer cell...

– West Virginia University

Software Framework Designed to Accelerate Drug Discovery Wins IEEE International Scalable Computing Challenge

Designing a new pharmaceutical drug takes years of research, and now chemists and computational and computer scientists have developed a software framework that could help expedite this process by supporting accurate and rapid calculations of how str...

– Brookhaven National Laboratory

Loyola Offering Intraoperative Radiation Therapy to Broad Range of Cancer Patients

Loyola Medicine is among the select centers that offer a broad range of cancer patients a leading-edge form of radiation therapy that is delivered during surgery.

– Loyola University Health System

Expanding the Boundaries of Genomic Detection, Cancer Therapies, Population Health, and Pain Treatment at the 70th AACC Annual Scientific Meeting

At the 70th AACC Annual Scientific Meeting & Clinical Lab Expo—the premier global conference and exhibit for laboratory medicine—trailblazers in the field will share the pioneering research and technology paving the way for better clinical testin...

– American Association for Clinical Chemistry (AACC)

70th AACC Annual Scientific Meeting, Jul-Aug 2018

Embargo expired on 29-Jul-2018 at 18:00 ET

Dense Breast Notification and Insurance Legislation Analysis

Increased awareness of breast tissue density masking cancer and thus decreasing the diagnostic sensitivity of mammography has brought about relevant state-level policies. This new study by Harvey L. Neiman Health Policy Institute examines which char...

– Harvey L. Neiman Health Policy Institute

Medical Care

Researcher Finds Risk of Later Death After Donor Blood, Marrow Transplant in Childhood

While blood and marrow transplants can save the life of a pediatric cancer patient, research out of the University of Alabama at Birmingham found that those patients may be at an increased risk of premature death even years or decades after the proce...

– University of Alabama at Birmingham

JAMA Oncology

UCI center to advance the use of artificial intelligence in healthcare

UCI artificial intelligence center will develop, apply deep learning neural networks to diagnostics, disease prediction and therapy planning. Initial research includes developing a system with 97%+ accuracy in near real-time detection of brain bleeds...

– University of California, Irvine

Research Shows Free Skin Cancer Screenings Can Help Save Lives

For more than 30 years, board-certified dermatologists have been providing free skin cancer screenings in their communities through the AAD’s SPOTme® program — and research published today highlights the value of that program.

– American Academy of Dermatology

Journal of the American Academy of Dermatology

Combined Approach Offers Hope to Lung Cancer Patients Who Become Resistant to Drugs

Drug resistance is an all-too-common occurrence in cancer treatment. Now, working with physicians at Chaim Sheba Medical Center, the Weizmann Institute of Science’s Prof. Yossi Yarden has identified a three-drug combo that fends off drug resistance...

– Weizmann Institute of Science

Clinical Cancer Research, July-2018

Switching Sides: The Betrayal of an Anti-Cancer Gene

Continuing his groundbreaking p53 studies, the Weizmann Institute of Science’s Prof. Moshe Oren has shown how cancer cells within the tumor microenvironment – in particular, within the fibroblasts – can “brainwash” the p53 gene into helping...

– Weizmann Institute of Science

PNAS, June-2018

Artwork May Help Improve Patients’ Perceptions of Their Hospital Experience

Patients’ perceptions of the hospital they’re being treated in may be improved by the type of artwork hanging in hospital rooms, according to Penn State College of Medicine researchers.

– Penn State College of Medicine

The Journal of Hospital Medicine

New Strategy for Cancer Therapy Spells Double Trouble for Tumors

The study, published recently in Nature Communications, shows that a molecule in cells, called Rad52, repairs special kinds of damaged DNA that accumulate in some cancers.

– Scripps Research Institute

Nature Communications, July 2018; CA187052; CA197995; GM080677; CA179441; CA193124-Project 3; 2015CB910602; 31370841

Tobacco Regulation Advocates Get Support from Medical Professional Organizations in Court Filing

The American Thoracic Society led 10 medical professional organizations in filing an amicus brief last week regarding the FDA’s failure to apply pre-market review to new tobacco products. The brief was submitted in support of the American Academy...

– American Thoracic Society (ATS)

2019 International Conference, May 17-22, 2019

Newly Identified Target May Help with Drug Discovery for Chronic Inflammatory Diseases

In a study published online July 25 in the journal Nature, University of California San Diego School of Medicine researchers identified a signaling pathway that activates the NLRP3 inflammasome implicated in several severe chronic inflammatory disord...

– University of California San Diego Health


Fitness Trackers Prove Helpful in Monitoring Cancer Patients

Fitness trackers can be valuable tools for assessing the quality of life and daily functioning of cancer patients during treatment, a new study has found. The trackers, also known as wearable activity monitors, include commercial devices worn on the ...

– Cedars-Sinai

npj Digital Medicine


Foundation for the National Institutes of Health and Cancer Research Institute Announce New Collaboration in Cancer Immunotherapy

FNIH has selected CRI to be its source of landscape intelligence in immuno-oncology, also called cancer immunotherapy

– Cancer Research Institute and the Foundation for the National Institutes of Health

Bayshore Medical Center Launches Y-90 Radioembolization Outpatient Tumor Treatment

Hackensack Meridian Health Bayshore Medical Center now offers Y-90 radioembolization, an advanced and minimally invasive method to treat liver tumors without surgery. This procedure is used to treat patients who are not surgical candidates, but who h...

– Hackensack Meridian Health

Rogel Cancer Center awarded $33.4M from NCI

The National Cancer Institute has awarded the University of Michigan Rogel Cancer Center a grant worth $33.4 million over five years. At the same time, the center’s designation as a “comprehensive cancer center” was renewed.

– Michigan Medicine - University of Michigan


Making Every Step Count

Cindy Blair, PhD, was recently awarded a five-year $750,000 grant that will allow her to explore ways to help older cancer survivors in New Mexico become more active and study how being more active affects their health.

– University of New Mexico Comprehensive Cancer Center


American Society for Radiation Oncology (ASTRO) elects new officers to its Board of Directors

The members of the American Society for Radiation Oncology (ASTRO) have elected four new officers to ASTRO’s Board of Directors and four members to serve on the medical society’s Nominating Committee. The newly elected President-elect, Council Vi...

– American Society for Radiation Oncology (ASTRO)

ASTRO’s 60th Annual Meeting, to be held October 21-24, 2018

Dr. Benjamin Movsas Elected Education Council Vice-Chair of ASTRO’s Board of Directors

Benjamin Movsas, M.D., FASTRO, chair of the Department of Radiation Oncology at Henry Ford Cancer Institute, has been elected to serve as Education Council Vice-chair on the American Society for Radiation Oncology Board of Directors.

– Henry Ford Health System

Leaders in radiation oncology awarded ASTRO Fellow designation

The American Society for Radiation Oncology (ASTRO) has selected 35 distinguished members to receive the ASTRO Fellow (FASTRO) designation. The 2018 class of Fellows will be recognized during ASTRO’s 60th Annual Meeting, to be held October 21-24 in...

– American Society for Radiation Oncology (ASTRO)

ASTRO’s 60th Annual Meeting, to be held October 21-24, 2018

New, Revised ACR Practice Parameters and Technical Standards Cover 27 Radiology Topics

The American College of Radiology (ACR) has released four new and 23 revised documents in the 2018 Practice Parameters and Technical Standards.

– American College of Radiology (ACR)

Enzo Launches New High Quality, Cost-Effective p16INK4A Monoclonal Antibody

Enzo is pleased to announce the launch of a new primary antibody validated for IHC, our p16INK4a monoclonal antibody. Our antibody is specific to the p16INK4A protein, a cyclin-dependent kinase inhibitor that plays an important regulatory role in the...

– 70th AACC Annual Scientific Meeting Press Program

Dr. Indrin J. Chetty named Fellow of the American Society for Radiation Oncology

Indrin J. Chetty, Ph.D., has been selected to be a Fellow of the American Society for Radiation Oncology (ASTRO).

– Henry Ford Health System

Immunologist Named Chair of Systems Pharmacology

John Wherry, PhD, has been appointed the new chair of the department of Systems Pharmacology and Translational Therapeutics at Penn. He is an international leader in the study of T cell exhaustion, which prevents optimal control of infections and can...

– Perelman School of Medicine at the University of Pennsylvania

Penn Medicine


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