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Newswise Special Wire
Tuesday, August 14, 2018

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Newswise Cancer Research Wire for 14-Aug-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Large Collection of Brain Cancer Data Now Easily, Freely Accessible to Global Researchers

A valuable cache of brain cancer biomedical data, one of only two such large collections in the country, has been made freely available worldwide by researchers at Georgetown Lombardi Comprehensive Cancer Center.

– Georgetown Lombardi Comprehensive Cancer Center

Nature; P30 CA51008

Embargo expired on 14-Aug-2018 at 09:00 ET

Zombie gene protects against cancer — in elephants

LIF6, a dead gene that came back to life, prevents cancer by killing cells with DNA damage.

– University of Chicago Medical Center

August 14, 2018 Cell Reports

Embargo expired on 14-Aug-2018 at 11:00 ET

Mount Sinai Researchers Artificially Generate Immune Cells Integral to Creating Cancer Vaccines

For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports.

– Mount Sinai Health System

Cell Reports, Aug-2018

Embargo expired on 14-Aug-2018 at 11:00 ET

Better Doctor/Patient Communication Means Better Outcomes in Cancer Care, According to a Report in JNCCN

Study from the American Cancer Society, published in JNCCN--Journal of the National Comprehensive Cancer Network, found cancer patients who were more satisfied with the communication they received, had better health results at lower costs

– National Comprehensive Cancer Network® (NCCN®)

JNCCN—Journal of the National Comprehensive Cancer Network

Embargo expired on 14-Aug-2018 at 09:25 ET

Research Shows Surprising Scale of Health Benefits for Biggest Losers

When it comes to shedding pounds, it pays to think big, according to new research by The University of Texas Health Science Center at Houston (UTHealth).

– University of Texas Health Science Center at Houston

Mayo Clinic

Doctor-Patient Discussions Neglect Potential Harms of Lung Cancer Screening, Study Finds

Although national guidelines advise doctors to discuss the benefits and harms of lung cancer screening with high-risk patients because of a high rate of false positives and other factors, those conversations aren’t happening the way they should be,...

– University of North Carolina Health Care System

JAMA Internal Medicine, August-2018

Embargo expired on 13-Aug-2018 at 11:00 ET

Duke Team Finds Missing Immune Cells That Could Fight Lethal Brain Tumors

Researchers at Duke Cancer Institute have tracked the missing T-cells in glioblastoma patients. They found them in abundance in the bone marrow, locked away and unable to function because of a process the brain stimulates in response to glioblastoma,...

– Duke Health

Nature Medicine; 1R01NS099096-01

University Hospitals Seidman Cancer Center Opens Car-T Therapy Study for Non-Hodgkin’s Lymphoma

University Hospitals Seidman Cancer Center in Cleveland has a new clinical trail to study the safety of CAR-T therapy for Non-Hodgkin's lymphoma. In addition, UH is manufacturing on-site the cells used in the trial.

– University Hospitals Cleveland Medical Center

Late effects of treatment hinder independence of adult survivors of childhood brain tumors

In the first study of its kind, St. Jude Children’s Research Hospital investigators have found that more than half of pediatric central nervous system tumor survivors do not achieve complete independence as adults. Researchers looked at six aspects...

– St. Jude Children's Research Hospital

Journal of Clinical Oncology, August 9

Embargo expired on 09-Aug-2018 at 16:00 ET

Drugs in Development for Cancer May Also Fight Brain Diseases, including ALS

A class of cancer drugs called PARP inhibitors could be useful for treating and preventing brain disorders, including ALS (Lou Gehrig’s disease) and some forms of frontotemporal degeneration, by halting the misplacement of specific proteins that af...

– Perelman School of Medicine at the University of Pennsylvania

Molecular Cell; R01 NS095746-01, R21NS093439, 5R21NS087077-02, R01GM099836, R21NS090205, 5R01NS073660, R35NS097275

Embargo expired on 09-Aug-2018 at 11:00 ET

Scientists Identify Genetic Marker for Gastric Cancer Prognosis

Although immunotherapy is seen as a very promising treatment for cancer, currently only 20 to 30 percent of patients respond positively. Being able to identify the people most likely to benefit from the costly therapy is a Holy Grail for oncologists....

– Wake Forest Baptist Medical Center

JAMA Oncology, Aug-2018

An Ancient Medicine Shows New Promise: Arsenic in Combination with an Existing Drug Could Combat Cancer

Investigators have discovered that arsenic in combination with an existing leukemia drug work together to target a master cancer regulator. The team, led by researchers at the Cancer Center at Beth Israel Deaconess Medical Center, is hopeful that the...

– Beth Israel Deaconess Medical Center

Nature Communications; CA167677; CA205153

New Study Views Cancer Treatment as a Game to Find Strategies That Improve Patient Outcomes

TAMPA, Fla. – Game theory can be utilized to identify potential flaws in current cancer treatment approaches and suggest new strategies to improve outcomes in patients with metastatic cancer, according to a new article published online today by JAM...

– Moffitt Cancer Center

JAMA Oncology

Discovery Could Lead to Better Treatment for Leukemia

Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess this favorable mutation...

– University of Illinois at Chicago

JCI Insight

Scientists Uncover New Details in How Sense of Smell Develops

Researchers at Washington University School of Medicine in St. Louis have uncovered new details in how the olfactory epithelium develops. The new knowledge could help scientists prove that turbinates and the resulting larger surface area of the olfac...

– Washington University in St. Louis

Developmental Cell

First FDA-Approved Study of Focused Ultrasound to Open Blood-Brain Barrier

In the first such clinical trial in the United States, physician-scientists with the University of Maryland School of Medicine (UMSOM) are investigating the use of MRI-guided focused ultrasound to open the blood-brain barrier. The trial will be condu...

– University of Maryland Medical Center/School of Medicine

Mount Sinai Researchers Create RNA and DNA-Sequencing Platform to Match Broader Swath of Cancer Drugs to Patients With Few Options

A comprehensive RNA and DNA sequencing platform benefits late-stage and drug-resistant multiple myeloma patients by determining which drugs would work best for them, according to results from a clinical trial published in JCO Precision Oncology in Au...

– Mount Sinai Health System

JCO Precision Oncology, Aug-2018

Embargo expired on 08-Aug-2018 at 16:00 ET

Johns Hopkins Kimmel Cancer Center Researchers Using Big Data to Predict Immunotherapy Responses

In the age of Big Data, cancer researchers are discovering new ways to monitor the effectiveness of immunotherapy treatments.

– Johns Hopkins Medicine

Cancer Immunology Research; P30 CA006973, 01 CA203891-01A1, SU2C/AACR, SU2C-AACR-DT1012, CA121113, CA180950

No single test identifies all ROS1+ lung cancer patients

University of Colorado Cancer Center study shows that common laboratory tests used to determine ROS1 status may return false-negative results, meaning that some patients who could benefit from ROS1-directed therapy may be slipping through the cracks....

– University of Colorado Cancer Center

Journal of Thoracic Oncology; P30-CA046934; P50 CA058187

Genetic Mutations of Appendix Cancer Identified, May Impact Treatment

To understand why some patients with appendix cancer respond to standard treatment while others do not, University of California San Diego School of Medicine and Moores Cancer Center researchers, in collaboration with Foundation Medicine, performed g...

– University of California San Diego Health

JCO Precision Oncology

فريق البحث الذي تتولى قيادته Mayo Clinic يُحدد الجينات التي تُزيد من خطر الإصابة بسرطان الثدي الثلاثي السلبي

روتشستر، مينيسوتا. – حدد فريق البحث الذي تتولى قيادته Mayo Clinic جينات معينة ترتبط بزيادة خطر الإصابة بسرطان الثدي الثلاثي السلبي. وقد تم نشر...

– Mayo Clinic

Journal of the National Cancer Institute

Taking a Pill Can Effectively Treat Brutal Lung Disease

Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis (PAP), and they show taking cholesterol-busting pills ca...

– Cincinnati Children's Hospital Medical Center

Nature Communications, Aug. 7, 2018

Blue-light technology improves identification of bladder cancer

Blue-light cystoscopy has previously been available at some institutions, including UT Southwestern, for use in the operating room, but it wasn’t available in a flexible scope until now.

– UT Southwestern Medical Center

Policy and Public Affairs

American College of Rheumatology: New CMS Decision an Affront to America’s Sickest Medicare Patients

The American College of Rheumatology (ACR) today expressed its extreme disappointment with a new Centers for Medicare and Medicaid Services (CMS) decision to allow Medicare Advantage (MA) plans to implement step therapy for Part B drugs and cross-man...

– American College of Rheumatology (ACR)


Research Grant to Study Common Resistance to Papillary Thyroid Cancer Treatment Is Awarded to Ann-Kathrin Eisfeld, MD, by the American Thyroid Association

The American Thyroid Association has awarded a 2018 Research Grant to Ann-Kathrin Eisfeld, MD, Clinical Fellow in Internal Medicine at Ohio State University. The topic of Dr. Eisfeld’s project is “Novel NRAS isoform mediates BRAF-inhibitor resist...

– American Thyroid Association

Research Grant to Determine the Genes Responsible for Survival and Growth of Medullary Thyroid Cancer Is Awarded to Wayne Miles, PhD, by the American Thyroid Association

The American Thyroid Association has awarded a 2018 Research Grant to Wayne Miles, PhD, Assistant Professor of Molecular Genetics at the Ohio State University. Dr. Miles’s research project is entitled “Proteomic-led discovery of essential genes i...

– American Thyroid Association

Keck Medicine of USC Hospitals Ranked Among the Country’s Best for 10th Year in a Row

U.S. News & World Report’s 2018–2019 Best Hospitals rankings place Keck Medicine of USC hospitals among the top 50 nationwide in nine specialties, the top three in Los Angeles and the top seven in California.

– Keck Medicine of USC

Keck Medicine of USC Ranks Highest in Southern California for Cancer Care

Keck Medicine of USC leads as Southern California’s highest-ranked cancer care provider, with cancer mortality rates that are the second-lowest in the nation, according to U.S. News & World Report’s Best Hospitals report.

– Keck Medicine of USC

Seattle Cancer Care Alliance again ranked in the Top 10 in the nation for adult cancer care

Seattle Cancer Care Alliance (SCCA) / University of Washington Medical Center (UWMC) is ranked among the best in the nation for adult cancer care by U.S. News & World Report for 2018-2019.

– Seattle Cancer Care Alliance

U.S. News & World Report Ranks Cedars-Sinai Among Top 10 Hospitals

Cedars-Sinai Medical Center been recognized by U.S. News & World Report’s “Best Hospitals 2018–19” as one of the 10 best hospitals in the nation. The medical center ranked No. 8 in a select group of 20 Honor Roll hospitals and also had 12 med...

– Cedars-Sinai

MD Anderson and Accelerator Life Science Partners Launch Magnolia Neurosciences to Speed Development of Neuroprotective Therapies

The University of Texas MD Anderson Cancer Center and Accelerator Life Science Partners, a leading life science investment and management firm, today announced the launch of Magnolia Neurosciences Corporation, a company developing a new class of neur...

– University of Texas M. D. Anderson Cancer Center

Research Grant for Study of Resistance to Precision Medication for Medullary Thyroid Cancer Is Awarded to Brendan Frett, PhD, by the American Thyroid Association

The American Thyroid Association has awarded a 2018 Research Grant to Brendan Frett, PhD, Assistant Professor in the College of Pharmacy at the University of Arkansas for Medical Sciences. The title of Dr. Frett’s project is “Dual Inhibition of R...

– American Thyroid Association

$1M Commitment from Embrace Kids Foundation Supports Recruitment of Pediatric Cancer Research Faculty at Rutgers Cancer Institute of New Jersey

Rutgers Cancer Institute of New Jersey now has additional resources in the fight against pediatric cancers and blood disorders, thanks to a $1 million commitment from Embrace Kids Foundation that will support the recruitment of pediatric cancer resea...

– Rutgers Cancer Institute of New Jersey

Research Grant to Determine How Specific Drugs Work or Fail in Anaplastic Thyroid Cancer Is Awarded to Miles Miller, PhD, by the American Thyroid Association

The American Thyroid Association has awarded a 2018 Research Grant to Miles Miller, PhD, principal investigator at the Massachusetts General Hospital Center for Systems Biology and Assistant Professor of Radiology at Harvard Medical School. Dr. Mille...

– American Thyroid Association

For the 50 Million

7th DC Metro Autoimmune Walk -- Linking Together for a Cure

– American Autoimmune Related Diseases Association (AARDA)

Embargo expired on 13-Aug-2018 at 00:00 ET

AACI Members Choose Knudsen President-Elect, Four Added to Board of Directors

The members of the Association of American Cancer Institutes (AACI) have elected Karen E. Knudsen, PhD, as vice president/president-elect of AACI’s board of directors. In addition to Dr. Knudsen, four leaders of AACI member cancer centers will join...

– Association of American Cancer Institutes (AACI)

NDSU Research Foundation and OncoThira Announce License Agreement to Develop & Market Compounds Discovered at NDSU for the Treatment of Cancer

OncoThira will develop and market compounds discovered by NDSU pharmaceutical sciences researcher Steven Qian that take advantage of high COX-2 expression in cancer to down regulate cancer promoting prostaglandins and elevate production of the recent...

– North Dakota State University

FAU Scientist Receives $708,044 from Florida Department of Health for Cancer Metastasis Research

A leading scientist has been working to identify what contributes to the ability of tumor cells to move through the body and find other places to “set up shop.” He has identified a number of enzymes that he believes are responsible for this proce...

– Florida Atlantic University

Cleveland Clinic Researchers Receive $4.7M NIH Grant to Prevent Cancer-Associated Thrombosis

The National Heart, Lung and Blood Institute (NHLBI), part of the National Institutes of Health, awarded a $4.7 million grant to Cleveland Clinic to study the prevention of life-threatening, cancer-associated blood clots. The new funding will support...

– Cleveland Clinic

Inaugural Class of the Michael Brown Penn-GSK Postdoctoral Fellowship Award Program Commence Unique Collaborative Training

Four Penn Medicine postdoctoral trainees have been awarded three-year fellowships through a newly established program, the Michael Brown Penn-GSK Postdoctoral Fellowship Award Program from the Perelman School of Medicine at the University of Pennsylv...

– Perelman School of Medicine at the University of Pennsylvania

Penn Medicine





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