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Newswise Special Wire
Tuesday, September 11, 2018

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Newswise Cancer Research Wire for 11-Sep-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Researchers Identify a Potential Strategy in Fight Against Brain Cancer

Scientists with the Virginia Tech Carilion Research Institute say a gene involved in the body’s sleep cycle is a potential target for therapies to help patients with a deadly form of brain cancer known as glioblastoma. This discovery, to be publ...

– Virginia Tech

Scientific Reports

Embargo expired on 11-Sep-2018 at 05:00 ET

Decoding Robotic Surgery Skills

Researchers from the Keck School of Medicine of USC are looking to technology to help deconstruct expert surgeons’ robotic surgery skills so they can create an objective, standardized way to train the next generation of surgeons.

– Keck Medicine of USC

The Journal of Urology

Stress linked to more advanced disease in some leukemia patients

Patients with chronic lymphocytic leukemia (CLL) who feel more stress also have more cancer cells in their blood and elevated levels of three other markers of more advanced disease.

– Ohio State University


New Guidelines Provide Vital Information for Women Diagnosed with the Most Common Type of Gynecologic Cancer

National Comprehensive Cancer Network publishes NCCN Guidelines for Patients: Uterine Cancer during Gynecologic Cancer Awareness Month to explain treatment options and raises awareness of endometrial cancer, the most common type of gynecologic cancer...

– National Comprehensive Cancer Network® (NCCN®)

Loyola Medicine Pediatric Cancer Patient Drafted by Chicago Cubs

Teen baseball players overcomes cancer to see his dream of being drafted come true.

– Loyola University Health System

McMaster study identifies an unexpected cell population key to blood cancer relapse

The study published today in the journal Cancer Cell suggests that leukemia cells change in unique ways in response to the chemotherapy, allowing them to masquerade for a short time so they are able to start disease regeneration.

– McMaster University

Cancer Cell

Embargo expired on 10-Sep-2018 at 11:00 ET

Study Links BAP1 Protein to Tumor Suppression in Kidney, Eye, Bile Duct and Mesothelioma Cancers

Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called fer...

– University of Texas M. D. Anderson Cancer Center

Nature Cell Biology

Embargo expired on 10-Sep-2018 at 11:00 ET

Optimizing Technologies for Discovering Cancer Cell Mutations

A team of researchers has developed a new framework that can combine three existing methods of finding mutations -- or structural variants -- in the DNA of cancer cells into a single, more complete picture.

– Penn State College of Medicine

Nature Genetics

Embargo expired on 10-Sep-2018 at 11:00 ET

Changes in the Architecture Around Cancer Cells Can Fuel Their Spread

UCLA researchers have found that an often overlooked component of a cell, the extracellular matrix, can influence how much sugar the cell consumes and its migratory behavior.

– University of California, Los Angeles (UCLA), Health Sciences


New Flexible Robotic Scope Enables Physicians to Remove Large Colorectal Lesions without Surgery

Robotic scope enables physician to successfully remove lesions that cannot be removed by endoscopy without the patient needing surgery.

– NYU Langone Health

Scanning Thousands of Molecules Against an Elusive Cancer Target

Researchers at the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health, have developed a system to accelerate the discovery of chemical compounds that inhibit an enzyme implicated in a number of can...

– American Society for Biochemistry and Molecular Biology (ASBMB)

Journal of Biological Chemistry, August 2018

Tetris-Like Program Could Speed Breast Cancer Detection

Researchers from the University of Adelaide’s Australian Institute for Machine Learning (AIML) are developing a fully-automated medical image analysis program to detect breast tumours. The program uses a unique style to focus on the affected area. ...

– University of Adelaide

Roswell Park Team Identifies Possible Cause of Resistance to Prostate Cancer Treatment

A Roswell Park-led research team has linked the development of castration-resistant prostate cancer and resistance to treatment to a lack of androgen receptor expression in prostate cancer cells, identifying a new therapeutic target. Their findings w...

– Roswell Park Comprehensive Cancer Center

Nature Communications; R01CA155693; P30CA016056; P01CA77739

Ovarian Cancer: Quick Steps to Widespread Disease

Ovarian cancer cells that interact with cancer-associated fibroblasts can mobilize glycogen as an energy source, leading to proliferation, invasion and metastasis. Blocking glycogen mobilization in cancer cells might reduce tumor spread.

– University of Chicago Medical Center

Cell Metabolism

Mayo Clinic physicians receive Stand up to Cancer Catalyst Award for melanoma research

Mayo Clinic physicians Matthew Block, M.D., Ph.D. and Tina Hieken, M.D., have received a Stand up to Cancer (SU2C) Catalyst Award to fund melanoma research and a neoadjuvant clinical trial.

– Mayo Clinic

Modular Fluidic System Developed to Supply Radioisotope Used in Targeted Alpha Therapy

Laboratory automation applied to complex radiochemical isolation of astatine-211 from cyclotron-bombarded targets.

– Department of Energy, Office of Science

Applied Radiation and Isotopes 122, 202 (2017). [DOI: 10.1016/j.apradiso.2017.02.001]

Enhancing the Efficacy of Immune Checkpoint Inhibitor Therapy Using a Novel Treatment Combination

A combination of a novel inhibitor of the protein CK2 (Casein kinase 2) and an immune checkpoint inhibitor has dramatically greater antitumor activity than either inhibitor alone, according to research from The Wistar Institute that was published onl...

– Wistar Institute

Cancer Research

Scientists Identify Weak Point in Deadly Eye Melanoma

A natural plant compound exploits a newly identified Achilles’ heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according...

– Washington University in St. Louis

Science Signaling

GW Researcher Investigating Link between Parasitic Infection and Bile Duct Cancer

Paul Brindley, PhD, at the GW School of Medicine and Health Sciences, has received more than $1.7 million from the National Cancer Institute at the National Institutes of Health to investigate the cellular and molecular links between liver fluke infe...

– George Washington University

2 R01 CA164719-06A1

Clinical Trial Shows Best Outcomes to Date for Older Hodgkin Lymphoma Patients

Recently published results of a phase 2 clinical trial have shown the best outcomes to date for newly diagnosed older Hodgkin lymphoma patients treated with brentuximab vedotin given before and after doxorubicin, vinblastine and dacarbazine (AVD) che...

– Rutgers Cancer Institute of New Jersey

Journal of Clinical Oncology, Sept-2018

Embargo expired on 04-Sep-2018 at 16:00 ET

Hormone Therapy Can Make Prostate Cancer Worse, Study Finds

Scientists at Cedars-Sinai have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing the cancer to spread. Their findings also point to a simple blood test that may help doctors predict when this type ...

– Cedars-Sinai

Journal of Clinical Investigation, Sept. 4, 2018

Fred Hutch Tip Sheet: Next-generation CAR T-cell immunotherapies; rural-urban cancer care disparities; organizing chromosomes in egg and sperm cells

The August tip sheet from Fred Hutch includes story ideas about next-gen CAR T-cell immunotherapies, cancer care disparities in rural and urban settings, organizing chromosomes in egg and sperm cells, decoding our immune system's memories and more. ...

– Fred Hutchinson Cancer Research Center


Press Briefing on Recent Clinical and Preclinical Advances in Focused Ultrasound

Revolutionary Noninvasive Therapy Shows Promise for Immunotherapy and Opening Blood-Brain Barrier to Enable Treatment of Neurological Disease and Cancer

– Focused Ultrasound Foundation

6th International Symposium on Focused Ultrasound

MD Anderson immunotherapy expert Sharma wins Coley Award

Padmanee Sharma, M.D., Ph.D., professor of Genitourinary Medical Oncology and Immunology at The University of Texas MD Anderson Cancer Center, has been recognized for her innovative work understanding factors that enhance and hinder cancer immunother...

– University of Texas M. D. Anderson Cancer Center

U-M cancer researcher awarded $6.5M Outstanding Investigator Award to explore precision oncology

A new grant to University of Michigan Rogel Cancer Center member Arul Chinnaiyan, M.D., Ph.D., will provide long-term support to increase understanding of genetic markers to leverage targeted treatments for cancer.

– Michigan Medicine - University of Michigan


Three Scientists to Receive Top Honors From the Cancer Research Institute for Outstanding Contributions to Cancer Immunology and Immunotherapy

The Cancer Research Institute will bestow its highest honors on three scientists who have made fundamental contributions to the fields of immunology and cancer immunotherapy at its annual taking place on Thursday, October 25, 2018, at The Metropolita...

– Cancer Research Institute

Biotechnology Company Regeneron and Journalist and Filmmaker Perri Peltz to Receive the 2018 Oliver R. Grace Award for Distinguished Service in Advancing Cancer Research

he Cancer Research Institute will honor biotechnology company Regeneron, and journalist and filmmaker Perri Peltz with the 2018 Oliver R. Grace Award for Distinguished Service in Advancing Cancer Research at its annual gala taking place on Thursday, ...

– Cancer Research Institute

Renowned Lung Cancer Expert Joins Perlmutter Cancer Center

Nationally renowned clinician and researcher Vamsidhar “Vamsi” Velcheti, MD, recently joined Perlmutter Cancer Center at NYU Langone Health as Director of Thoracic Medical Oncology, enhancing the center’s efforts to improve clinical care, incre...

– NYU Langone Health

September Is Thyroid Cancer Awareness Month

Mount Sinai promotes early detection and announces new Thyroid Center in New York City

– Mount Sinai Health System

Hackensack Meridian Health John Theurer Cancer Center to Host 10th Annual Celebrating Life & Liberty

Hackensack Meridian Health John Theurer Cancer Center at Hackensack University Medical Center, one of the nation’s top 50 hospitals for cancer, will host its tenth annual Celebrating Life and Liberty event at MetLife Stadium, featuring special perf...

– Hackensack Meridian Health

AACI/CCAF Annual Meeting Considers Shape of Things to Come in Cancer Research

The 2018 joint annual meeting of the Association of American Cancer Institutes and the Cancer Center Administrators Forum, September 30 – October 2, will highlight perspectives on the future of cancer research and care, and the latest on CAR T-cell...

– Association of American Cancer Institutes (AACI)





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