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Newswise Special Wire
Tuesday, October 16, 2018

Public edition |

Newswise Cancer Research Wire for 16-Oct-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

ISPOR Publishes New Report on the Application of Constrained Optimization Methods in Healthcare

ISPOR—the professional society for health economics and outcomes research (HEOR), has published a new Good Practices for Outcomes Research Report that illustrates how constrained optimization methods can be used to assess the value of health techno...

– ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health,Sep-2018

Mapping Genetic Differences in Breast Cancer Can Improve Care for Underserved Populations

A new study comparing DNA and RNA data from Nigerian breast cancer patients to patients in a United States database found that aggressive molecular features were far more prevalent in tumors from women of African ancestry than women of European ances...

– University of Chicago Medical Center

Nature Communications, Oct. 16, 2018

Researchers Identify a New Way to Determine Whether Metastatic Cancer Cells in Breast Cancer Patients are Dormant or Soon to Turn Deadly

Protein Can Be Used to Monitor Patients and Identify Drugs

– Mount Sinai Health System

Breast Cancer Research, Oct-2018

Embargo expired on 15-Oct-2018 at 20:00 ET

More Clues Revealed in Link Between Normal Breast Changes and Invasive Breast Cancer

A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process — changes in mammary glands to accommodate breastfeeding — uses a molecular process believed to contribute to s...

– Georgetown University Medical Center

Cell Death Discovery; U01-CA184902; U54-CA149147424; P30-CA51008; BC112023

Embargo expired on 15-Oct-2018 at 00:15 ET

Function of Neutrophils During Tumor Progression Unraveled

Wistar researchers have characterized the function of neutrophils, a type of white blood cells, during early stages of tumor progression, showing that they migrate from the bone marrow to distant sites and facilitate tumor cell seeding and establishm...

– Wistar Institute

Nature Immunology

Embargo expired on 15-Oct-2018 at 11:00 ET

Updated Breast Cancer Resources and Events from NCCN Keep Patients and Doctors Worldwide Informed during Breast Cancer Awareness Month

NCCN publishes updated patient and clinical guidelines for breast cancer in conjunction with free webinars. New NCCN Harmonized Guidelines for the Caribbean released for breast cancer and other types. Global Summit on International Breast Health and ...

– National Comprehensive Cancer Network® (NCCN®)

NUS researchers elucidate roles of transcription factors, TP63 and SOX2, in squamous cell cancer progression

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have identified a SCC-specific protein complex activated by TP63 and SOX2 which triggers a gene cascade that promotes SCC growth.

– National University of Singapore

Nature Communications

Dompé at the medical conference “The Impact of Environment and Healthy Lifestyles in Human Health” - October 13th, Washington, D.C

Sbarro Health Research Organization, on the occasion of the medical conference “The impact of environment and healthy lifestyles in human health,” honoured Nathalie Dompé, CEO Dompé Holdings, with a special Award for Societal Impact in Business...

– Sbarro Health Research Organization (SHRO)

National Italian American Foundation (NIAF) Convention

Cancer Stem Cells Use “Normal” Genes in Abnormal Ways

University of Colorado Cancer Center study shows that "normal" gene CDK1 interacts with "abnormal" gene Sox2 to keep cancer stem cells "stemmy."

– University of Colorado Cancer Center

Cancer Research

Científicos de Mayo Clinic identifican tipos genéticos que llevan a disparidades raciales en el mieloma

Los científicos de Mayo Clinic identificaron tres tipos específicos de genes a los que se atribuye el aumento al triple de los diagnósticos de mieloma entre los afroamericanos. Los científicos también demostraron que se puede estudiar la raza y ...

– Mayo Clinic

Blood Cancer Journal

Obesity linked to increased risk of early-onset colorectal cancer

Women who are overweight or obese have up to twice the risk of developing colorectal cancer before age 50 as women who have what is considered a normal body mass index (BMI), according to new research led by Washington University School of Medicine i...

– Washington University in St. Louis

JAMA Oncology

Pesquisadores da Mayo Clinic identificam tipos de genes que geram disparidades raciais no mieloma

Pesquisadores da Mayo Clinic identificaram três tipos de genes específicos que explicam um aumento conhecido de duas a três vezes no diagnóstico de mieloma entre afro-americanos. Os pesquisadores também demonstraram a capacidade de estudar raça...

– Mayo Clinic

Blood Cancer Journal

Mayo Clinic的研究人员确定了导致骨髓瘤种族差异的基因类型

Mayo Clinic的研究人员已经确定了三种特定的基因类型,这些基因类型会使非洲裔美国人的骨髓瘤(myeloma)诊断增加两到三倍。 研究人员还展示了DNA分析在更准确地研究种族和种族混合上的效...

– Mayo Clinic

Blood Cancer Journal

Is the Next Big Step in Cancer Therapy Personalized Vaccines?

Tamara Strauss has been living with high-grade, stage IV pancreatic neuroendocrine cancer for more than three years. Current treatments, although effective for her, are highly toxic. Tamara enrolled in a first-of-its-kind, pilot study at Moores Cance...

– University of California San Diego Health

University Hospitals Seidman Cancer Center Becomes First in U.S. To Use Newly FDA-Approved Drug That Makes Brain Tumors Glow Hot Pink

Dr. Andrew Sloan of University Hospitals Seidman Cancer Center becomes first neurosurgeon to use 5-ALA in the U.S. following its FDA approval for brain cancer surgery.

– University Hospitals Cleveland Medical Center

Ethanol Injection a Viable Treatment Option for Some Thyroid Problems

Ultrasound-guided percutaneous ethanol ablation for thyroid conditions is a minimally invasive procedure that is quick and cost-effective, with side effects about the same as those of a flu shot.

Expert Available

– Wake Forest Baptist Medical Center

Blood Test Identifies More Treatable Cancer Mutations Than Tissue Biopsy Alone

In one of the largest clinical studies to ever examine the impact of using a blood test to detect treatable mutations in non-small cell lung cancer (NSCLC), researchers from the Abramson Cancer Center of the University of Pennsylvania found that they...

– Perelman School of Medicine at the University of Pennsylvania

JAMA Oncology; KL2TR001879

Embargo expired on 11-Oct-2018 at 11:00 ET

Latest Cornell dot features a new cancer weapon: antibodies

Ulrich Wiesner, the Spencer T. Olin Professor of Engineering in materials science and engineering at Cornell University, in collaboration with Dr. Michelle Bradbury of Memorial Sloan Kettering Cancer Center (MSKCC) and Weill Cornell Medicine, has pro...

– Cornell University

Nature Communications, Oct. 2018

Study Holds Promise for New Pediatric Brain Tumor Treatment

New research published in Nature Communications from scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U), in collaboration with the Stanford University School of Medicine, shows a specific protein regulates both the initi...

– Huntsman Cancer Institute at the University of Utah

Nature Communications, Oct. 2018

New ASTRO/ASCO/AUA guideline for early-stage prostate cancer supports use of shortened courses of radiation therapy

Three prominent medical societies today issued a new clinical guideline for physicians treating men with early-stage prostate cancer using external beam radiation therapy (EBRT). Adoption of the guideline could make treatment shorter and more conveni...

– American Society for Radiation Oncology (ASTRO)

Practical Radiation Oncology, Oct-2018; Journal of Clinical Oncology, Oct-2018; The Journal of Urology, Oct-2018

New Clinical Trials Seek Treatments for Canine Cancers, May Offer Clues on Human Cancers

Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs with mast cell tumors and...

– Tufts University

U01CA224182 - National Cancer Institute of the National Institutes of Health

Modeling how genes are expressed in specific cell types

A computational model that can track how genes are expressed in each cell type within tissue may help scientists unravel how diseases, such as cancer, progress and how they evade treatment.

– South Dakota State University

Fred Hutch November Tip Sheet

Fred Hutch is committed to better understanding prostate cancer, creating new treatment therapies and technologies and ultimately, finding a cure. This tip sheet includes brief summaries of the work our researchers are doing around prostate cancer an...

– Fred Hutchinson Cancer Research Center

Cancer Patients with Rare Deadly Brain Infection Treated Successfully with Off-the-Shelf Adoptive T-Cell Therapy in Clinical Trial

An emerging treatment known as adoptive T-cell therapy has proven effective in a Phase II clinical trial for treating progressive multifocal leukoencephalopathy (PML), a rare and often fatal brain infection sometimes observed in patients with cancer ...

– University of Texas M. D. Anderson Cancer Center


Embargo expired on 10-Oct-2018 at 17:00 ET

New study finds that inflammatory proteins in the colon increase incrementally with weight

A new study from Tufts researchers finds that two inflammatory proteins in the colon increase incrementally with weight. In individuals with obesity, this was accompanied by activation of precancerous cellular pathways.

– Tufts University

Cancer Epidemiology, Biomarkers & Prevention, Oct-2018

Lung Cancer Deaths are 28 Percent Lower in California

Early adoption of tobacco control efforts in California lead to fewer people ever smoking, reduced the amount used by those who do smoke and helped smokers quit at a younger age — when their risk of developing lung cancer is lowest. As a result, lu...

– University of California San Diego Health

Cancer Prevention Research

More Than $41,000 Raised for Skin Cancer Prevention and Detection Through “Skin Cancer, Take a Hike!™ - Chicago”

On Sat., Sept. 29, more than 200 dermatologists, skin cancer survivors and their families and friends hiked four miles at Busse Woods to tell “Skin Cancer, Take a Hike!” Together, they raised more than $41,000 for SPOT Skin Cancer™ to benefit t...

– American Academy of Dermatology

Skin Cancer, Take a Hike!™ – Chicago


Prostate cancer patients target of new $1.6M Tulane study

A Tulane University researcher will work to develop a tool that could lower tumor recurrence in cancer patients, especially those with prostate cancer.

– Tulane University

Stem cell biologist Sean Morrison elected to the National Academy of Medicine

UT Southwestern Professor Dr. Sean Morrison, Director of the Children’s Medical Center Research Institute (CRI) at UT Southwestern, has been elected to the National Academy of Medicine (NAM), one of the highest honors in the fields of health and me...

– UT Southwestern Medical Center

Mia Levy, MD, PhD, Appointed Director of the Rush University Cancer Center

Mia Levy, MD, PhD, a practicing oncologist and nationally-recognized leader in biomedical informatics, has been appointed director of the Rush University Cancer Center.

– Rush University Medical Center

Young Innovators

A special issue of the journal Cellular and Molecular Bioengineering will recognize assistant professors Emily Day and Jason Gleghorn as Young Innovators, while featuring their latest research.

– University of Delaware

Cellular and Molecular Bioengineering

Partnership Bolsters Childhood Cancer Research

The Treehouse Childhood Cancer Initiative of the UC Santa Cruz Genomics Institute and Dr. Elaine Mardis with other members of the Nationwide Children’s Hospital’s Institute for Genomic Medicine (IGM) recently met to bolster an ongoing collaborati...

– University of California, Santa Cruz

Rutgers Cancer Institute of New Jersey Biospecimen Repository and Histopathology Service Shared Resource Receives Accreditation from College of American Pathologists

The Biospecimen Repository and Histopathology Service shared resource at Rutgers Cancer Institute of New Jersey has received accreditation from the College of American Pathologists (CAP) based on results of a recent on-site inspection as part of the ...

– Rutgers Cancer Institute of New Jersey

Cedars-Sinai Expert Joins Team Researching Rare Blood Cancer

Ronald Paquette, MD, clinical director of the Cedars-Sinai Blood & Marrow Transplant Program at the Samuel Oschin Comprehensive Cancer Institute, recently was accepted as a member of the Myeloproliferative Neoplasm Research Consortium. The group is f...

– Cedars-Sinai

NIH awards WVU $11.2 million for interdisciplinary cancer research

West Virginia University’s School of Pharmacy will soon become one of the few pharmacy schools in the nation that leads a center of biomedical research excellence.

– West Virginia University

National Institute of General Medical Sciences of the National Institutes of Health/ 1P20GM121322

Expert Pitch

Rutgers Expert Available to Discuss Recent Expanded HPV Vaccine Mid-Adult Indication And Policies Surrounding Decision

– Rutgers University-New Brunswick

What does it mean if you have dense breasts? Breast density describes different kinds of tissue that show on your mammogram.

– University Hospitals Cleveland Medical Center





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