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Newswise Special Wire
Tuesday, October 23, 2018

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Newswise Cancer Research Wire for 23-Oct-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

HPV blood test shows promise for tracking head and neck cancer after treatment

Researchers will present preliminary findings at the 60th Annual Meeting of the American Society for Radiation Oncology in San Antonio on Tuesday, Oct. 23, from a study evaluated a blood test for HPV-linked oropharyngeal squamous cell carcinoma.

– University of North Carolina Health Care System

American Society for Radiation Oncology 60th Annual Meeting

Embargo expired on 23-Oct-2018 at 08:45 ET

Mutation in Common Protein Triggers Tangles, Chaos Inside Brain Cells

A pioneer in the study of neural cells revealed today (Oct. 23, 2018) how a single mutation affecting the most common protein in a supporting brain cell produces devastating, fibrous globs. These, in turn, disturb the location of cellular processing ...

– University of Wisconsin-Madison

Cell Reports October 23, 2018

Embargo expired on 23-Oct-2018 at 11:00 ET

Biomarker blood test accurately confirms remission in patients with HPV-associated oral cancer

A highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related oropharyngeal squamous cell carcinoma (OPSCC) are free from cancer following radiation therapy. F...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Oct-2018

New radiotherapy treatment for brain cancer offers superior preservation of cognitive function, Mayo researchers say

When it comes to radiation therapy to treat brain cancer, hippocampal-avoidance whole-brain radiotherapy in conjunction with the drug memantine better preserved patients’ cognitive function and demonstrated similar cancer control outcomes, compared...

– Mayo Clinic

UG1CA189867 (NCORP); U10CA180868 (NRG Oncology Operations)

New study finds harmful pesticides lurking in NYS homes

Despite the existence of chemical-free methods to eradicate pests, Americans use more than a billion pounds of pesticides per year. These chemicals are mostly out of sight and out of mind to unsuspecting homeowners, who are typically unaware of how t...

– Cornell University

JSM Health Education & Primary Health Care, Sept-2018

AACI Launches National CAR T-cell Therapy Initiative

The Association of American Cancer Institutes (AACI) has established a national initiative to advance the use of chimeric antigen receptor T-cell therapies (CAR T). Joseph McGuirk, DO, division director of the Hematologic Malignancies and Cellular Th...

– Association of American Cancer Institutes (AACI)

Researchers Use New AI Techniques in Clinical Trials for Personalized Cancer Treatment

Researchers are finding new ways to use artificial intelligence and nanotechnology to enhance treatments, from routine dental techniques to attacking cancerous tissue. At the AVS 65th International Symposium and Exhibition, Oct. 21-26, Dean Ho will p...

– AVS: Science and Technology of Materials, Interfaces, and Processing

AVS 65th International Symposium and Exhibition

Embargo expired on 22-Oct-2018 at 08:00 ET

RNA Thought to Spread Cancer Shows Ability to Suppress Breast Cancer Metastasis

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a form of RNA called metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) appears to suppress breast cancer metastasis in mice, suggesting a potential ne...

– University of Texas M. D. Anderson Cancer Center

Nature Genetics

Embargo expired on 22-Oct-2018 at 11:00 ET

Future Fertility: Giving Hope to Men Who Received Childhood Cancer Treatment

Researchers have discovered a way to grow human stem cells destined to become mature sperm in an effort to provide fertility options later in life to males who are diagnosed with cancer and undergo chemotherapy and radiation as children.

– Perelman School of Medicine at the University of Pennsylvania

T32 CA009140, R01 CA118374

Embargo expired on 22-Oct-2018 at 05:00 ET

Combined therapy including pelvic lymph node radiation provides significant benefit for prostate cancer patients

The first report of a large international clinical trial shows that, for men who show signs of prostate cancer after surgical removal of their prostates, extending radiation therapy to the pelvic lymph nodes combined with adding short-term hormone th...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Oct-2018

Embargo expired on 22-Oct-2018 at 12:00 ET

Radiation Therapy Outcomes Better for African-American Prostate Cancer Patients Than Caucasian Patients

While popular beliefs and population data suggest that African-American men are at higher risk of dying from prostate cancer than Caucasian men, a new analysis of genetic data from a large prospective registry and clinical data from several randomize...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Oct-2018

Embargo expired on 22-Oct-2018 at 12:00 ET

Men with low- and intermediate-risk prostate cancer can safely benefit from fewer, higher-dose radiation treatments

Stereotactic body radiation therapy (SBRT) is a safe and effective treatment for men with low- and intermediate-risk prostate cancer, according to a long-term, multi-institutional study. The study clears the way for patients who may wish to shorten t...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Oct-2018

Embargo expired on 22-Oct-2018 at 12:00 ET

High-dose, high-precision radiation therapy safe and effective for kidney cancer patients with only one kidney

Treatment of renal cell carcinoma with stereotactic radiation therapy is as safe and effective for patients with one kidney as it is for those who have two, according to an analysis of the largest-ever, international dataset of solitary kidney patien...

– American Society for Radiation Oncology (ASTRO)

Cancer; ASTRO Annual Meeting, Oct-2018

Embargo expired on 22-Oct-2018 at 12:00 ET

Radiation/cisplatin combination established as standard of care for HPV-related head and neck cancer

Combinations of radiation and chemotherapy drugs have been shown to cure HPV-related head and neck cancer with a high success rate. A new phase III trial has now determined that cisplatin chemotherapy, combined with radiation therapy, produces the be...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Oct-2018

Embargo expired on 22-Oct-2018 at 15:15 ET

Scientists Identify Critical Cancer Immunity Genes Using New Genetic Barcoding Technology

Novel gene editing technique reveals cancer weakness in the immune system and opens possibilities to identify disease-causing genes and new drug targets

– Mount Sinai Health System

Cell, Oct-2018

Urban and Rural Rates of Childhood Cancer Survival the Same, Study Finds

Childhood and adolescent cancer survival in the United States does not vary by rural/urban residence at the time of diagnosis, finds a new study from the Brown School at Washington University in St. Louis.“The widespread availability of public heal...

– Washington University in St. Louis

Cancer, Oct. 12, 2018

New tool gives deeper understanding of glioblastoma

Researchers in the lab of Charles Danko at the Baker Institute for Animal Health have developed a new tool to study genetic “switches” active in glioblastoma tumors that drive growth of the cancer. In a new paper in Nature Genetics, they identifi...

– Cornell University

Nature Genetics, Oct-2018

Pancreatic Cancer Genetic Marker May Predict Outcomes with Radiation Therapy

Research scientists find that a gene involved in the immune system called IDO2 plays a significant role in pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer. The discovery may help physicians provide better treatment ...

– Thomas Jefferson University

Clinical Cancer Research

Marker Found for Condition That Causes Numerous Tumors

UT Southwestern researchers have made a major advance in uncovering the biology of how thousands of disfiguring skin tumors occur in patients troubled by a genetic disorder called neurofibromatosis type 1 (NF1). This scientific advance could slow the...

– UT Southwestern Medical Center

Cancer Discovery

Study shows surgery, radiation extend survival of patients with limited metastatic lung cancer

Radiation or surgical removal of metastatic tumors provides a major survival advantage for lung cancer patients with minimal stage 4 disease who have not progressed after frontline chemotherapy, a study led by researchers from The University of Texas...

– University of Texas M. D. Anderson Cancer Center

60th Annual Meeting of the American Society for Radiation Oncology, October 21 - 24, 2018

Embargo expired on 21-Oct-2018 at 14:10 ET

Johns Hopkins Researchers Present at Rheumatology Annual Meeting

The 2018 American College of Rheumatology/American Rheumatology Health Professionals Annual Meeting.

– Johns Hopkins Medicine

Embargo expired on 20-Oct-2018 at 17:30 ET

Treatment of Aggressive Breast Cancer Improved by Immunotherapy-Chemotherapy Combination

Progression free survival in triple-negative breast cancer increased when immunotherapy-chemotherapy treatment combination is used as the first treatment option.

– Health Sciences at the University of Pittsburgh

New England Journal of Medicine ; European Society for Medical Oncology

Updated Global Immuno-Oncology Landscape Report Highlights Robust International Pipeline Marked by Rapid Growth

The Cancer Research Institute has updated its analysis of the global immuno-oncology landscape, published today in Nature Reviews Drug Discovery.

– Cancer Research Institute

Nature Reviews Drug Discovery Oct 19, 2018.

Award-Winning Nuclear Physics Technology Monitors Cancer Treatments

Nearly a half-million cancer patients are treated with radiation therapy every year in the United States. Now, technologies developed in partnership with the Department of Energy's Thomas Jefferson National Accelerator Facility (Jefferson Lab) are he...

– Thomas Jefferson National Accelerator Facility

Compound Derived From Chinese Tree Bark Shows Promise as Treatment for Pancreatic Cancer

A new derivative of a compound found in the bark of a rare Chinese tree has powerful anticancer properties and a low toxicity profile, according to new research from a Roswell Park Comprehensive Cancer Center published in the Journal of Experimental ...

– Roswell Park Comprehensive Cancer Center

Journal of Experimental & Clinical Cancer Research.; R21CA180764; R03CA182552; R44CA17693; P30CA016056

Childhood Trauma, Depression Linked to Higher Risk of Longer-Term Fatigue in Breast Cancer Survivors

Breast cancer survivors who experienced trauma early in life and depression after their cancer treatments are at increased risk of persistent fatigue, a new UCLA study shows. Some of the key predictors of longer-term fatigue for this group of women i...

– University of California, Los Angeles (UCLA), Health Sciences

Health Psychology

NYU Langone Hospital–Brooklyn Welcomes Breast Cancer Specialist

Based in Brooklyn and working in collaboration with the already outstanding breast cancer team at NYU Langone Hospital–Brooklyn under the auspices of Perlmutter Cancer Center at NYU Langone, Magdalena Plasilova, MD, PhD, specializes in “hidden sc...

Expert Available

– NYU Langone Hospital - Brooklyn

Revolutionary Noninvasive Therapy Shows Promise for Immunotherapy and Opening Blood-Brain Barrier to Enable Treatment of Neurological Disease and Cancer

A briefing featuring key data presented at the 6th International Symposium on Focused Ultrasound. Researchers and clinicians will highlight breakthrough advances in the use of focused ultrasound in cancer immunotherapy and for opening the blood-brain...

– Focused Ultrasound Foundation

6th International Symposium on Focused Ultrasound

High-Dose Radiation Therapy Substantially Improves Survival in Patients Once Thought to Be Incurable

In the first randomized, phase II clinical trial of its kind, researchers have shown that an aggressive form of high-precision radiation therapy can greatly increase how long oligometastatic patients live and doubles how long they live without cancer...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Oct-2018

Cellular clean-up crews linked to how body handles sugar

How our bodies handle glucose—the simple sugar that provides energy from the food we eat—appears to be intertwined with how cells keep themselves functioning normally, according to new University of Chicago research.

– University of Chicago


NCCN Awarded $2 Million in Research Funding from Taiho Oncology to Study Trifluridine and Tipiracil in Various Cancers

The National Comprehensive Cancer Network’s Oncology Research Program received a grant to investigate effectiveness of trifluridine and tipiracil for treatment of people with colorectal, gastric, and other cancers

– National Comprehensive Cancer Network® (NCCN®)

21 Mercy Physicians Named Among Region’s “Top Docs” in November 2018 Issue of Baltimore Magazine

A total of 21 Mercy Medical Center physicians were recognized in Baltimore Magazine’s November 2018 “Top Docs” issue, representing 19 separate specialties, ranging from breast cancer surgery to pediatrics to urogynecology.

– Mercy Medical Center, Baltimore

Abramson Cancer Center Receives $10.7 Million to Study CAR T Cells in Solid Tumors

new program project grant from the National Cancer Institute (NCI) will fund research by the Translational Center of Excellence for Lung Cancer Immunology at the Abramson Cancer Center of the University of Pennsylvania to improve the effectiveness o...

– Perelman School of Medicine at the University of Pennsylvania

Mount Sinai Opens World-Class Thyroid Center in Manhattan’s Union Square

New facility offers comprehensive care to enhance patient experience

– Mount Sinai Health System

$4.5 Million From NIH Will Help Find Solutions to ‘Chemo Brain’ Symptoms and Opioid Addiction

Pain researcher Daniela Salvemini, Ph.D., will embark on two new research projects, studying chemotherapy-induced cognitive impairment, or “chemo brain,” symptoms and unwanted side effects of opioids.

– Saint Louis University Medical Center

Study Aims to Build a Better Model for Brain Tumors

A research team led by UAB is launching a study to find a better model for glioblastoma, a particularly devastating type of brain tumor, to help determine the most appropriate treatment modality.

– University of Alabama at Birmingham

Case Comprehensive Cancer Center Receives $3M NIH Grant for Health Disparities Research

The Case Comprehensive Cancer Center has received a three-year, $3,194,947 grant from the National Cancer Institute to investigate colorectal and breast cancer health disparities. The grant is one of only four Specialized Programs of Research Excelle...

– Case Western Reserve University


La Jolla Institute Receives $ 4.5 Mill Cancer Moonshot Award

Researchers at La Jolla Institute for Immunology (LJI) and UC San Diego have been awarded $ 4.5 million as part of the National Cancer Institute’s Cancer Moonshot initiative. The funding will support research to develop new and improved immunothera...

– La Jolla Institute for Immunology

NIH UO1 DE028277

The Association of American Cancer Institutes Appoints New Executive Director

Jennifer W. Pegher, MA, is the new executive director of the Association of American Cancer Institutes. She is the second executive director in AACI's 19-year history, succeeding founding executive director Barbara Duffy Stewart, who retired earlier ...

– Association of American Cancer Institutes (AACI)





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