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Newswise Special Wire
Tuesday, October 30, 2018

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Newswise Cancer Research Wire for 30-Oct-2018
 

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.



Temple University's Katz School of Medicine, Hunter College Awarded $13.5M NCI/NIH Grant for Cancer Health Disparities

This joint grant, a first of its kind for any Pennsylvania or New Jersey institution, will examine cancer health inequity across multiple ethnic populations

– Temple University

Embargo expired on 30-Oct-2018 at 00:05 ET


Obese Mice Lose a Third of Their Fat Using a Natural Protein

To the great surprise of cancer researchers in a Georgetown University-led study, a protein they investigated for its possible role in cancer turned out to be a powerful regulator of metabolism.

– Georgetown Lombardi Comprehensive Cancer Center

Scientific Reports; P01 HL068686; R01 CA71508; P30 CA51008; 2016-01381

Embargo expired on 29-Oct-2018 at 05:00 ET


Biologists Discover Source for Boosting Tumor Cell Drug Sensitivity

Biologists have discovered a new way of re-sensitizing drug-resistant tumor cells to DNA-damaging agents, the most widely used group of cancer drugs. Researchers describe how a gene known as Schlafen 11 controls the sensitivity of tumor cells to DDAs...

– University of California San Diego

Nature Structural and Molecular Biology, Nov-2018

Embargo expired on 29-Oct-2018 at 12:00 ET


Scientists Neutralize Reactive Nitrogen Molecules to Enhance Cancer Immunotherapy

Researchers at the University of Notre Dame studying tumors in prostate cancer models found that nitration of an amino acid can inhibit T-cell activation, thwarting the T-cell’s ability to kill cancer cells.

– University of Notre Dame

Proceedings of the National Academy of Sciences


Radiation therapy cuts low risk of recurrence by nearly three-fourths for patients with “good risk” breast cancer

A subset of patients with low-risk breast cancer is highly unlikely to see cancer return following breast conservation surgery but can lower that risk even further with radiation therapy, finds a new long-term clinical trial report. These 12-year fol...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Oct-2018


Aggressive treatment for some stage IV lung cancer patients can dramatically improve overall survival

Adding radiation therapy or surgery to systemic therapy for stage IV lung cancer patients whose cancer has spread to a limited number of sites can extend overall survival time significantly, according to new results from a multicenter, randomized, co...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Oct-2018


Long-Term Side Effects Similarly Low for Once-Weekly and Conventional Breast Radiation Therapies, Trial Finds

In a 10-year study of women who received radiation therapy to treat early-stage breast cancer, those receiving fewer, larger individual doses experienced similarly low rates of late-onset side effects as those undergoing conventional radiation therap...

– American Society for Radiation Oncology (ASTRO)

ASTRO Annual Meeting, Oct-2018


Small risks may have big impact on breast cancer odds of childhood cancer survivors

St. Jude Children’s Research Hospital scientists found that the combined effect of common genetic variations can dramatically increase risk of breast cancer for female pediatric cancer survivors

– St. Jude Children's Research Hospital

Clinical Cancer Research


Three Proteins May Play Key Roles in Female Fertility and Cancer Biology

Three proteins regulate each other with surprising twists and turns in female mouse eggs, a finding that may play an important role in female fertility and cancer biology, according to Rutgers-led research.

– Rutgers University-New Brunswick

Current Biology


Head and Neck Cancer Survivors at Increased Risk of Suicide

Despite improved survival rates among cancer patients, the risk of death by suicide remains high, especially among those treated for head and neck cancers (HNC).

– Saint Louis University Medical Center

Cancer


The Body's Defence Mechanisms: Teamwork Is Key for Cancer-Fighting Proteins

A new study published in Nature Communications shows that a molecular symbiosis between BAP1 and ASXL2 proteins can suppress cancerous tumors.

– Universite de Montreal

Nature Communications, Oct 22 2018 ; Canadian Institutes of Health Research, Natural Sciences; Natural Sciences and Engineering Research Council of Canada; Mesothelioma Applied Research Foundation...


توصلت إحدى الدراسات إلى أن العلاج الإشعاعي الجديد لسرطان الدماغ يحافظ بشكل أفضل على الوظائف المعرفية

...

– Mayo Clinic


Obesity Problem Starts Early Phase of Therapy in Children with Acute Lymphoblastic Leukemia

Children with acute lymphoblastic leukemia (ALL) gain weight during treatment, and researchers at St. Jude Children’s Research Hospital have discovered that this problem starts during remission-induction treatment and suggests that early interventi...

– St. Jude Children's Research Hospital

Cancer, October 2018


Watching and Waiting: New Data Provides Guidance for Management of Moderately Dysplastic Moles

Study suggests close observation is a reasonable management strategy for moderately dysplastic moles, but certain patients require continued screening for risk for melanoma

– Beth Israel Deaconess Medical Center

JAMA Dermatology


Suppression of DKK3 protein thwarts pancreatic tumor progression and prolongs survival

Researchers at The University of Texas MD Anderson Cancer Center have shed new light on why pancreatic tumors are so resistant to therapy.

– University of Texas M. D. Anderson Cancer Center

Science Translational Medicine

Embargo expired on 24-Oct-2018 at 14:00 ET


Exploring an Oncolytic Virus Treatment Combined with Radiation against Melanoma

Can the combination of radiation therapy with an oncolytic virus treatment better boost the body’s immune response to melanoma than either treatment on its own? Investigators from Rutgers Cancer Institute of New Jersey further explored that questio...

– Rutgers Cancer Institute of New Jersey

ASTRO Annual Meeting, Oct-2018

Embargo expired on 24-Oct-2018 at 16:35 ET


T-cell biofactories find, fight disease in one fell swoop

NIBIB-funded researchers have transformed T cells into drug factories engineered to find cells carrying specific diseases in the body--and then produce therapeutic proteins localized to the diseased cells.

– National Institute of Biomedical Imaging and Bioengineering

Advanced Biosystems, Sept-2018; DP2EB024245; CA193064


Discovery of Pathway Leading to Growth of Colon Cancer Stem Cells Could Lead to New Possibilities in Colorectal Cancer Treatment

In a discovery that may have significant impact on the future of colon cancer treatment and research, scientists at the Helen F. Graham Cancer & Research Institute’s Center for Translational Cancer Research at Christiana Care Health System have def...

– Christiana Care Health System

Oncotarget


Grad Student Pursues Drug to Treat Aggressive Form of Blood Cancer

Multiple myeloma doesn’t play around. Within five years of being diagnosed with this form of blood cancer, about half of all patients die from it. And even if they initially respond well to treatment, the cancer can hide in their bone marrow for ye...

– West Virginia University


From Self-Exams to Immunotherapy, Breast Cancer Patients Tell All

As women scramble to keep up with work, family and the scores of chores they tackle, it’s easy for breast care to fall by the wayside. In recognition of Breast Cancer Awareness Month, Cedars-Sinai breast surgical oncologist Nimmi Kapoor, MD, breast...

– Cedars-Sinai


New combination treatment flips the switch on melanoma cells

Navitoclax plus A-1210477 not only killed melanoma cells, but also killed the melanoma initiating cells (aka cancer stem cells) that often resist therapy.

– University of Colorado Cancer Center

Cell Death & Disease


Researchers find potential new way to target lethal form of leukemia

New findings raise the possibility of a novel treatment for this subtype of blood and bone marrow cancer – known as acute myeloid leukemia or AML – by attacking a harmful molecule found on the cancerous cells and also reactivating the body’s wh...

– UT Southwestern Medical Center


研究发现,新的脑癌放疗可以更好地保留认知功能

当谈到放射治疗 脑癌时, 与使用美金刚的传统全脑放疗相比,避开海马的全脑放疗与药物联合使用美金刚在获得类似的癌症控制结果的同时能更好地保留患者的认知功能,。这些发现在美国圣...

– Mayo Clinic


Nova radioterapia para câncer cerebral preserva melhor a função cognitiva, diz estudo

Quando se fala em radioterapia para tratamento de câncer cerebral, a radioterapia de todo o cérebro com proteção do hipocampo em conjunto com o medicamento memantina preservou melhor a função cognitiva dos pacientes e demonstrou resultados seme...

– Mayo Clinic


Avoiding the Hippocampus During Whole-Brain Radiotherapy Prevents Cognitive Side Effects

Whole-brain radiotherapy can be delivered more safely to patients with brain metastases by avoiding the hippocampus according to a randomized phase III NRG Oncology trial presented at the American Society for Radiation Oncology (ASTRO) Annual Meeting...

– Northwestern Medicine

American Society for Radiation Oncology (ASTRO) Annual Meeting, Oct 2018


Nueva radioterapia para cáncer cerebral conserva mejor la función cognitiva, descubre estudio

Cuando se habla de radioterapia para tratar el cáncer cerebral, la radioterapia a todo el cerebro pero con evasión del hipocampo y administrada conjuntamente con el fármaco memantina conservó mejor la función cognitiva y mostró resultados oncol...

– Mayo Clinic


Fight CRC Partners with No-Shave November for Fourth Straight Year

Fight Colorectal Cancer (Fight CRC) has once again been selected by No-Shave November as one of the three recipients for all funds raised during the 2018 campaign.

– Fight Colorectal Cancer


Announcements


New Penn Medicine Center Brings Immunotherapy Research to Brain Tumor Treatment

Penn Medicine is announcing a new Translational Center of Excellence focused on Glioblastoma Multiforme, the most common and lethal form of brain cancer. The team will investigate new immune therapies for glioblastoma.

– Perelman School of Medicine at the University of Pennsylvania


UChicago Medicine Receives $6 Million to Prevent Colorectal Cancer

ACCSIS-Chicago—led by University of Chicago cancer specialists Karen Kim, MD, MS, and Blase Polite, MD, MPP—has been awarded nearly $6 million over five years to test novel ways to improve CRC screening and follow-up among groups that have not be...

– University of Chicago Medical Center

1UG3CA233229-01


$1.6M in Fellowship Grants Awarded to Early-Career Investigators Mentored by Rutgers Cancer Institute of New Jersey and Princeton University Scientists

Mentored by scientists from Rutgers Cancer Institute of New Jersey at Princeton University and Rutgers University, early-career investigators received a combined $1,600,000 in funding to support basic science research that could impact breast, colore...

– Rutgers Cancer Institute of New Jersey


Miriam Merad, MD, PhD, Receives Top Award for Contributions to Cancer Immunology and Immunotherapy

Miriam Merad, MD, PhD, Director of the Precision Immunotherapy Institute and the program leader of the Cancer Immunology and Immunotherapy Group at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, has received the Cancer Res...

– Mount Sinai Health System


Mount Sinai's Digital 3D Mammography Van Rolls Into New York City

New Program Designed to Break Down Barriers to Breast Cancer Screening

– Mount Sinai Health System


Rush Receives $5 Million Gift for Cancer Immunotherapy Research

Rush University Medical Center has received a $5 million donation from Chicago philanthropists Robert and Emily King that will accelerate blood cancer immunotherapy research and the development of new treatment options. This transformational gift to ...

– Rush University Medical Center


WANTED: Safe Return of the Stolen Inflatable Colon

The American College of Gastroenterology will donate $1,000 to charity for any tips that lead to the location and safe return of the stolen inflatable colon.

– American College of Gastroenterology (ACG)


Rutgers Cancer Institute of New Jersey Pediatric Hematology/Oncology Section Chief Honored for Contributions to Cancer and Blood Disorders

Richard Drachtman, MD, clinical section chief of the Pediatric Hematology/Oncology Division at Rutgers Cancer Institute of New Jersey, has been named the 2018 recipient of the Melvyn H. Motolinsky Research Foundation Distinguished Service Award in r...

– Rutgers Cancer Institute of New Jersey


Higher Education Events


Rock Docs Bring Healing and Awareness

The words ‘no evidence of disease’ sound like the most beautiful music to people with cancer. So the band, No Evidence of Disease (N.E.D.) – whose members also happen to be gynecological cancer doctors – chose it as their name. N.E.D. will gi...

– University of New Mexico Comprehensive Cancer Center


Expert Pitch


Fight Colorectal Cancer Awards Grant to Researchers Studying Early-Age Onset Colorectal Cancer.

– Fight Colorectal Cancer


Breast cancer experts from Rutgers discuss what is new in research, clinical guidelines, and myths surrounding male breast cancer in honor of breast cancer awareness month

– Rutgers University-New Brunswick

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