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Newswise Special Wire
Tuesday, November 6, 2018

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Newswise Cancer Research Wire for 06-Nov-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

How Melanoma Evades Targeted Therapies

New research shows how metastatic melanoma becomes resistant to a common class of targeted therapy.

– Thomas Jefferson University

Cell Reports

Embargo expired on 06-Nov-2018 at 11:00 ET

New checkpoint inhibitor shows promise in clinical trial for non-Hodgkin’s lymphoma

By combining the experimental anti-cancer antibody known as 5F9 with the anti-cancer antibody rituximab, researchers managing a phase 1b clinical trial were able to induce a positive response in 11 out of 22 people with relapsed/refractory non-Hodgki...

– University of Chicago Medical Center

New England Journal of Medicine, 11-1-2018; Cell

Pediatric Brain Tumor Patients Treated with Proton Therapy Have Favorable Cognitive Outcomes Relative to X-ray Radiation Therapy

Proton therapy treatment for pediatric brain tumor patients is associated with better neurocognitive outcomes compared to x-ray radiation therapy according to a study by Northwestern Medicine

– Northwestern Medicine

International Journal of Radiation Oncology Nov. 1 2018

Dana-Farber Scientists Find New Drug Targets in Aggressive Cancers

Scientists have discovered a previously unknown molecular vulnerability in two rare, aggressive, and hard-to-treat types of cancer, and say it may be possible to attack this weakness with targeted drugs.

– Dana-Farber Cancer Institute

Nature Cell Biology,

Yale Cancer Center investigators show recommended, but underused treatment for rare blood cancer saves lives

U.S. and European guidelines on treating Polycythemia Vera (PV), a potentially deadly blood cancer, call for two treatments for patients with high-risk disease: therapeutic phlebotomy and cytoreductive therapy with a drug called hydroxyurea (HU). HU ...

– Yale Cancer Center

Blood Advances


根据在线发表于《BMJ Supportive & Palliative Care》上的一项小型观察性研究的结果,玫瑰天竺葵精油有可能缓解鼻腔前庭炎的症状,这是一种与癌症药物治疗相关的常见鼻部疼痛症状。

– Mayo Clinic

Óleo de gerânio rosa pode aliviar sintomas nasais dolorosos relacionados ao tratamento de câncer

O óleo de gerânio rosa pode ajudar a aliviar os sintomas da vestibulite nasal, uma condição nasal comum e dolorosa relacionada ao tratamento medicamentoso de câncer, de acordo com o resultado de um breve estudo observacional publicado on-line no...

– Mayo Clinic

BMJ Supportive & Palliative Care

زيت زهرة الغرنوقي قد يخفف من الأعراض الشائعة لآلام الأنف والمرتبطة بعلاج السرطان


– Mayo Clinic

Inflammasomes and Parkinson’s Disease; Androgen Receptor High-Throughput Screening; and More Featured in November 2018 Toxicological Sciences

Description: Papers on inflammasomes and Parkinson’s disease; gas extraction and amphibian health; SeqAPASS; and androgen receptor HTS featured in latest issue of Toxicological Sciences.

– Society of Toxicology

Toxicological Sciences, Volume 166 Issue 1, November 2018

Twenty Years On, Measuring the Impact of Human Stem Cells

A paper published today (Nov. 1, 2018) in the journal Cell Stem Cell describes the global scope and economic impact of stem cell science, including the clinical, industrial and research use of the cells.

– University of Wisconsin-Madison

Cell, Stem Cell

Embargo expired on 01-Nov-2018 at 11:00 ET

High exposure to radio frequency radiation associated with cancer in male rats

The National Toxicology Program (NTP) concluded there is clear evidence that male rats exposed to high levels of radio frequency radiation (RFR) like that used in 2G and 3G cell phones developed cancerous heart tumors, according to final reports rele...

– National Institute of Environmental Health Sciences (NIEHS)


BIDMC Research & Health News Digest: October 2018

A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.

– Beth Israel Deaconess Medical Center

JAMA Dermatology; Trends in Cognitive Science; Nature Communications; Nature; Proceedings of the National Academy of Sciences; PLOS ONE

New Website Aims to Save Lives by Helping Institutions Launch Lung Cancer Screening Programs

The American Thoracic Society and the American Lung Association’s LUNG FORCE initiative have launched a new website and online toolkit to help medical institutions implement and manage a lung cancer screening program.

– American Thoracic Society (ATS)

Cold Therapy Offers Promising Prevention Against Taxane-Induced Dermatologic Events

Researchers at the George Washington University found skin cooling methods may be the best preventative intervention against taxane-based chemotherapy side effects.

– George Washington University

JAMA Dermatology

Embargo expired on 31-Oct-2018 at 11:00 ET

Minimally Invasive Surgery Associated with Worse Survival for Women with Cervical Cancer Compared to Open Hysterectomy

When comparing standard-of-care surgical options for women with early-stage cervical cancer, two studies led by researchers at The University of Texas MD Anderson Cancer Center discovered that minimally invasive radical hysterectomy is associated wit...

– University of Texas M. D. Anderson Cancer Center


Embargo expired on 31-Oct-2018 at 17:00 ET

Relapsed leukemia flies under immune system’s radar

A study from Washington University School of Medicine in St. Louis offers a potential explanation for why many AML patients experience a relapse after a stem cell transplant, and suggests a therapeutic approach that may help to place relapsed patient...

– Washington University in St. Louis

The New England Journal of Medicine.

Embargo expired on 31-Oct-2018 at 17:00 ET

Investigators study how a protein factor involved in making messenger RNA molecules also contributes to cancer cell migration

UCLA researchers have discovered a new protein factor that contributes to a fibroblast cell’s ability to migrate to a wound and participate in its healing process. The study’s results could help scientists prevent cancer cells from using the same...

– University of California, Los Angeles (UCLA), Health Sciences

Genome Biology

NUS study: RNA defects linked to multiple myeloma progression in high risk patients

Researchers from the Cancer Institute of Singapore (CSI Singapore) at the National University of Singapore have uncovered an association between RNA abnormalities and MM progression.

– National University of Singapore


Study finds 'alarming' rates of HPV prevalence among American Indian women

Naomi Lee, an assistant professor of chemistry and biochemistry at Northern Arizona University, is part of a team that found rates of HPV were four times higher among women 50-65 years old in AIAN communities than in the same age range of the general...

– Northern Arizona University

Journal of Infectious Diseases

Study Uncovers Key Parts of Mechanism for Activating T Cells to Fight Cancer and Other Diseases

In a study published online today by the journal Immunity, scientists at Dana-Farber Cancer Institute, Harvard Medical School, Vanderbilt University and colleagues at other institutions show how machinery within immune system T cells responds to outs...

– Dana-Farber Cancer Institute


Rose Geranium Oil May Ease Common Painful Nasal Symptoms Linked to Cancer Treatment

Rose geranium oil may help to ease the symptoms of nasal vestibulitis, a common and painful nasal condition linked to cancer drug treatment, according to the results of a small observational study, published online in the journal BMJ Supportive & Pal...

– Mayo Clinic

A New Tool to Help Fight an Old Enemy – Lung Cancer

In the U.S., lung cancer remains the leading cause of cancer death among both men and women. The primary reason for high death rates for lung cancer is the fact that this disease is typically detected in very late stages. A Rutgers University expert ...

Expert Available

– Rutgers Cancer Institute of New Jersey

Policy and Public Affairs

AACC Calls for Greater Federal Oversight of Medical Testing at Physician Offices, Pharmacies to Safeguard Patient Safety

With more and more medical tests being performed outside the traditional clinical laboratory, AACC released a position statement today emphasizing the need to ensure consistent high-quality testing at non-traditional facilities such as physician offi...

– American Association for Clinical Chemistry (AACC)


Exploring Autophagy in the Development of Non-Small Cell Lung Cancer

A Rutgers Cancer Institute of New Jersey researcher has received a $150,000 grant from the Lung Cancer Research Foundation to investigateautophagy in the development of lung cancers driven by mutations in tumor suppressors known as LKB1 and oncogene...

– Rutgers Cancer Institute of New Jersey

Rutgers Cancer Institute of New Jersey Physicians Named to Annual Listing of Top Doctors

A number of physicians at Rutgers Cancer Institute of New Jersey – the state’s only National Cancer Institute-designated Comprehensive Cancer Center – have been recognized by New Jersey Monthly magazine as a ‘Jersey Choice Top Doctor.’

– Rutgers Cancer Institute of New Jersey

USC Norris Comprehensive Cancer Center Appoints First Associate Director of Community Outreach and Engagement

USC Norris Comprehensive Cancer Center has appointed Lourdes Baezconde-Garbanati as the first associate director of community outreach and engagement to help reduce the cancer burden in surrounding communities.

– Keck Medicine of USC

Antonio Omuro named new Neuro-Oncology Chief at Yale Cancer Center

Antonio Omuro, M.D., has been appointed the new Chief of Neuro-Oncology and a Leader for the Brain Tumor Program at Yale Cancer Center (YCC) and Smilow Cancer Hospital.

– Yale Cancer Center

Three Endocrine Society members named to National Clinical Care Commission

Three Endocrine Society members have been appointed to the National Clinical Care Commission.

– Endocrine Society

Prime Minister of Canada Announces Establishment of Premier Centre for Advanced Medical IsotopeResearch and Development at TRIUMF

This afternoon, TRIUMF welcomed on-site The Right Honourable Justin Trudeau, Prime Minister of Canada, for a special visit and announcement about public investments into medical isotope research and innovation infrastructure.


Three Harvard Medical School Scientists Receive Prestigious Allen Awards

Three Harvard Medical School scientists have received the prestigious Allen Distinguished Investigator awards for their work in the fields of neuroimmunology, developmental biology and cancer.

– Harvard Medical School


Precision Medicine Leader Syapse to Utilize NCCN Biomarkers Compendium for Clinical Care

New agreement between National Comprehensive Cancer Network and Syapse will augment health information technology around precision medicine and biomarkers in cancer care

– National Comprehensive Cancer Network® (NCCN®)





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