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Newswise Special Wire
Tuesday, January 15, 2019

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Newswise Cancer Research Wire for 15-Jan-2019
 

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.



States with Fewer Melanoma Diagnoses Have Higher Death Rates

Researchers at University of Utah Health conducted a state-by-state analysis to understand the geographic disparities for patients diagnosed with melanoma. The results of their study suggest that lower survival is associated with more practicing phys...

– University of Utah Health

Journal of the American Academy of Dermatology

Embargo expired on 15-Jan-2019 at 10:00 ET


Muscle Stem Cells Can Drive Cancer That Arises in Duchenne Muscular Dystrophy

Scientists from Sanford Burnham Prebys Medical Discovery Institute (SBP) have demonstrated that muscle stem cells may give rise to rhabdomyosarcoma that occurs during DMD—and identified two genes linked to the tumor’s growth. The research, perfor...

– Sanford Burnham Prebys Medical Discovery Institute

Cell Reports; P30CA030199; P30AR061303; AG-NS-0843-11


Gene-Editing Tool CRISPR/Cas9 Shown to Limit Impact of Certain Parasitic Diseases

For the first time, researchers at the GW School of Medicine and Health Sciences have successfully used the gene-editing tool CRISPR/Cas9 to limit the impact of parasitic worms responsible for schistosomiasis and for liver fluke infection, which can ...

– George Washington University

eLife


Complication rates and costs of invasive lung cancer diagnostic tests may be higher than anticipated

Complication rates following invasive diagnostic procedures for lung abnormalities were twice as high in community settings compared to those reporter in lung screening trials, according to an MD Anderson study.

– University of Texas M. D. Anderson Cancer Center

JAMA Internal Medicine

Embargo expired on 14-Jan-2019 at 11:00 ET


Suicide Risk More Than Quadruples for People with Cancer

People with cancer are more than four times more likely to commit suicide than people without cancer, according to Penn State College of Medicine researchers.

– Penn State Health

Nature Communications

Embargo expired on 14-Jan-2019 at 05:00 ET


In breast-cancer prevention, race matters

African-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and racial disparities in health care and elsewhere are to blame, new research suggests.

– Ohio State University

Ethnicity & Health


More accurate leukemia diagnosis expected as researchers refine leukemia classification

More than 90 percent of B-ALL cases can now be classified by subtype, up from 70 percent several years ago. The number of proposed B-ALL subtypes is now 23.

– St. Jude Children's Research Hospital

Nature Genetics, Jan-2019


Herpes Viruses and Tumors Evolved to Learn How to Manipulate the Same Ancient RNA

Herpes viral infections use the ancient genetic material found in the human genome to proliferate, mimicking the same process tumors have been found to manipulate, Mount Sinai researchers have shown for the first time. These observations provide furt...

– Mount Sinai Health System

Nature Communications, Jan-2019


A Family Faces a Cancer Crisis Together

Catherine Carr Worley was 41 years old with a 2-month-old when she was diagnosed with inflammatory breast cancer.

– UT Southwestern Medical Center


VISTA checkpoint implicated in pancreatic cancer immunotherapy resistance

MD Anderson researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers.

– University of Texas M. D. Anderson Cancer Center

Proceedings of the National Academy of Sciences

Embargo expired on 11-Jan-2019 at 10:00 ET


Novel Biomarker Appears Predictive of Outcome in Patients with HPV-Related Head and Neck Cancers

Rather than classifying based solely on HPV status, MD Anderson researchers have discovered a new biomarker for head and neck cancers that may enable clinicians to better predict patient outcomes and lower treatment intensity to reduce side effects. ...

– University of Texas M. D. Anderson Cancer Center

JCI Insight

Embargo expired on 10-Jan-2019 at 09:00 ET


New biomarker links cancer progression to genome instability

Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and the food we eat. Genome insta...

– American Friends of Tel Aviv University

Cell


New Leukemia Drug is More Effective and Easier to Use

A landmark study has found that a newer targeted drug is significantly more effective than standard therapy for treating elderly patients with chronic lymphocytic leukemia (CLL). The drug, ibrutinib, attacks cancer cells without damaging normal cells...

– Loyola University Health System

New England Journal of Medicine


Metabolite produced by gut microbiota from pomegranates reduces inflammatory bowel disease

LOUISVILLE, Ky. - Scientists at the University of Louisville have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, can reduce and protect against inflammatory bowel disease (IBD). Millions of ...

– University of Louisville

Nature Communications


Protecting the Heart from Cancer Treatments

BIDMC cardiologists Aarti Asnani, MD, Loryn Feinberg, MD, and James Chang, MD, help cancer patients monitor and prevent cardiac complications.

– Beth Israel Deaconess Medical Center

Circulation


Pesquisadores da Mayo descobrem taxas de exame do câncer de colo do útero “inaceitavelmente baixas”

ROCHESTER, Minnesota. — A porcentagem de mulheres examinadas para câncer de colo do útero pode ser muito menor do que os dados dos Estados Unidos sugerem, de acordo com um estudo da Mayo Clinic publicado recentemente no Journal of Women’s Healt...

– Mayo Clinic

Journal of Women’s Health


UCLA study overturns dogma of cancer metabolism theory – tumors not as addicted to glucose as previously thought

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held beli...

– UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research

Nature Communications, Jan-2019


A Long Shot Could Bear Fruit

Fifteen years after a chance meeting started their partnership, a compound that Jeffrey Arterburn, PhD, and Eric Prossnitz, PhD, discovered may lead to new skin cancer treatments. Pre-clinical studies have begun.

– University of New Mexico Comprehensive Cancer Center


The Medical Minute: Screenings, Vaccine Prevent Cervical Cancer

January is Cervical Health Awareness Month, and the National Cervical Cancer Coalition is urging women to make a New Year’s resolution to talk with their health care providers.

– Penn State Health


A Long Shot Could Bear Fruit

A compound discovered by Jeffrey Arterburn of New Mexico State University and Eric Prossnitz of University of New Mexico is currently in pre-clinical trials. if they go well, human trials will begin at a few sites around the country, led by the UNM C...

– New Mexico State University (NMSU)


Liver Transplant Patients Have Higher Prevalenceof Colon Cancer and Non-Hodgkin Lymphoma

Liver transplant patients over time experience an increasing trend toward colon cancer and non-Hodgkin lymphoma, according to a study led by a Loyola Medicine gastroenterologist. The study also found that lung and heart transplant patients have a hig...

– Loyola University Health System

American College of Gastroenterology


Mercy Colorectal Surgeon Dr. Jeffery Nelson Performs Minimally Invasive Outpatient Treatment for Hemorrhoids

Jeffery Nelson, M.D., FACS, FASCRS, Surgical Director of The Center for Inflammatory Bowel and Colorectal Diseases, Institute for Digestive Health & Liver Disease at Mercy Medical Center in Baltimore, MD, now offers patients a minimally invasive, out...

– Mercy Medical Center, Baltimore


Policy and Public Affairs


ASTRO applauds selection of Dr. Anand Shah for senior medical innovation role within CMS

The Chair of the American Society of Radiation Oncology (ASTRO) Board of Directors, Paul Harari, MD, FASTRO, issued the following statement today in support of Centers for Medicare and Medicaid Services (CMS) Administrator Seema Verma’s announcemen...

– American Society for Radiation Oncology (ASTRO)


Announcements


NCCN Guidelines Raise Standards for Cancer Care Worldwide by Exceeding 10 Million Downloads in 2018 — Up 26% Over 2017

The National Comprehensive Cancer Network® (NCCN®) announced that the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) were downloaded more than 10 million times in 2018; marking a 26% increase over 2017.

– National Comprehensive Cancer Network® (NCCN®)

Embargo expired on 15-Jan-2019 at 08:00 ET


Moffitt Cancer Center Hires New Vice Chair of the Department of Genitourinary Oncology

Manish Kohli, M.D., has joined Moffitt Cancer Center as the vice chair of the Department of Genitourinary Oncology. He also has an extensive research background, focusing on creating new ways to bring individualized care to patients.

– Moffitt Cancer Center


Penn’s Abramson Cancer Center Welcomes New Director’s Leadership Council Chair

The Abramson Cancer Center at the University of Pennsylvania announced today that Richard S. Schiffrin, Esq., has been appointed chair of the Center Director’s Leadership Council.

– Perelman School of Medicine at the University of Pennsylvania


First-in-Class DNA-encoded Monoclonal Antibody Therapy Rapidly Advances into the Clinic

Wistar, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc. announce the FDA has approved the initiation of a first-in-human clinical trial investigating safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody (DMA...

– Wistar Institute


Khabele Elected as ASCI Member

Dineo Khabele, MD, director of The University of Kansas Cancer Center’s gynecologic oncology division, has been elected a new member to the American Society for Clinical Investigation (ASCI) for 2019.

– University of Kansas Cancer Center


Marketplace


MD Anderson Cancer Center and Dragonfly Therapeutics announce strategic collaboration to take new immunotherapy candidates into clinical trials

The University of Texas MD Anderson Cancer Center and Dragonfly Therapeutics, Inc., today announced a strategic collaboration to bring Dragonfly’s TriNKET™ (tri-specific natural killer cell engager therapy) immunotherapy drug candidates to patien...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 15-Jan-2019 at 10:00 ET

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