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Newswise Special Wire
Tuesday, January 29, 2019

Public edition |

Newswise Cancer Research Wire for 29-Jan-2019

OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery and Diagnostics

A new review by researchers from the University of Calabria (Italy) explores OCTNs, a small but intriguing group of transporters that are opening new frontiers in drug design research for improving drug delivery and predicting drug-drug interactions....

– SLAS (Society for Laboratory Automation and Screening)

Sage Journals

John Theurer Cancer Center Leading Enrollment for Global Phase 2 WIZARD Study Evaluating DSP-7888 in Patients with Recurrent Glioblastoma

John Theurer Cancer Center at Hackensack Meridian Health Hackensack University Medical Center announced today that it is leading enrollment worldwide for WIZARD 201G, a global Phase 2 study in glioblastoma (GBM). The trial, sponsored by Boston Biomed...

– Hackensack Meridian Health

Innovative Ice-Free Scalp Cooling During Chemotherapy Prevents, Reduces Hair Loss for Breast Cancer Patients

Breast cancer patient Laura Carey returned to work one week after beginning chemotherapy, but without a demoralizing side-effect indicative of this type of cancer treatment – hair loss. Carey is among the first breast cancer patients at the Henry F...

Expert Available

– Henry Ford Health System

Surge Protector: Novel Approach to Suppressing Therapy-Induced Tumor Growth

In a recent groundbreaking study, a team of researchers led by BIDMC’s Dipak Panigrahy, MD, demonstrated that dead and dying cancer cells killed by conventional cancer treatments paradoxically trigger the inflammation that promotes tumor growth and...

– Beth Israel Deaconess Medical Center

Proceedings of the National Academy of Science (PNAS)

Novel endoscopy tool opens new doors for pancreatic cancer treatment

A significantly more effective, minimally invasive treatment for pancreatic tumors may be on the horizon, thanks to a new endoscopy tool created in the Penn State Department of Mechanical Engineering.

– Penn State College of Engineering

Eleven Health Screening Tests Every Woman Should Have

A list of screening tests for women recommended by family medicine specialist Lili Ann Lustig, DO, of University Hospitals.

Expert Available

– University Hospitals Cleveland Medical Center

Targeting an ‘Energy Crisis’ in the Treatment of Non-Small Cell Lung Cancer

Research from Rutgers Cancer Institute of New Jersey examined a potential approach to cancer therapy that disrupts a cancer cell’s ‘fuel supply’ by targeting a cellular survival mechanism known as autophagy. Using laboratory models for LKB1-de...

– Rutgers Cancer Institute of New Jersey

Genes & Development, Jan-2019

Embargo expired on 27-Jan-2019 at 17:00 ET

TTP El Paso ALS Clinics Complete First Year of Service

Few words can be as surprising and heartbreaking as when a doctor tells a patient, “I wish I could tell you that you have cancer, because at least we could do something about that.”

– Texas Tech University Health Sciences Center El Paso

Genetically Modified Virus Injection into Tumor Can Treat Metastatic Melanoma

Injection of a genetically modified virus that induces the body’s own immune cells to attack metastatic melanoma effectively treated almost 40 percent of patients with tumors that could not be surgically removed.

– American College of Surgeons (ACS)

Journal of the American College of Surgeons

Embargo expired on 25-Jan-2019 at 11:00 ET

MD Anderson study shows FGL2 protein may be an effective target for glioblastoma

Glioblastoma (GBM) does not attract robust T cell immune responses. FGL2 is highly expressed in GBM and when present in tumor cells, controls a specialized group of dendritic cells which activates T cells.

– University of Texas M. D. Anderson Cancer Center

Nature Communications

Induction of Potent Anticancer Immunity Through Rapid Tumor Antigen Identification and Conversion to Personalized Synthetic DNA Vaccines

Wistar scientists and collaborators demonstrated the utility of an optimized synthetic DNA vaccine platform for rapidly inducing immunity against unique combinations of tumor neoantigens.

– Wistar Institute

Cancer Immunology Research

Embargo expired on 24-Jan-2019 at 10:00 ET

Effective Method for Reducing Hospital Stay After ‘Whipple’ Operation

Implementing a new recovery pathway speeds time to next treatment for pancreatic cancer patients by 15 days, without increasing complication rates.

– Thomas Jefferson University

Keloids Linked to Early Onset and Late Stage Breast Cancer

Findings from a new study conducted by researchers at Henry Ford Health System suggest a link between keloids and increased risk of being diagnosed with breast cancer, particularly among African Americans. Keloids are benign fibroproliferative tumors...

– Henry Ford Health System

Triological Society’s Combined Section Meeting Jan. 24-26 in Coronado, California

Enzyme that breaks down amino acids may promote aging

Permanently arrested cell growth is known as "cellular senescence", and the accumulation of senescent cells may be one cause of aging in our bodies. Japanese researchers have discovered that a certain enzyme in our bodies promotes cellular senescence...

– Kobe University

Life Science Alliance

New Radiation Treatment Studied for Deadly Brain Tumor

Loyola Medicine is participating in a landmark trial of a new radiation treatment for patients with glioblastoma. After the tumor is removed, a high, focused dose of radiation is delivered directly to the tumor cavity to kill any microscopic cancer ...

– Loyola University Health System

NUS engineers develop novel strategy for designing tiny semiconductor particles for wide-ranging applications

NUS Engineers have developed a cost-effective and scalable strategy for designing tiny semiconductor particles known as transition metal dichalcogenide quantum dots (TMD QDs) which can potentially generate cancer-killing properties.

– National University of Singapore

Nature Communications

Gene-Expression Profiling Raises Costs for Cancer Care without Improving Outcomes for Low-Risk Breast Cancer Patients, According to Researchers

Researchers from Yale School of Public Health find that genetic profiling for cancer tumors is cost-effective for high- and medium-risk patients with breast cancer, but is unlikely to make a meaningful impact on treatment for low-risk patients, in st...

– National Comprehensive Cancer Network® (NCCN®)

JNCCN—Journal of the National Comprehensive Cancer Network

Embargo expired on 23-Jan-2019 at 09:30 ET

Targeted treatment shrinks deadly pediatric brain tumors

For children—whose tiny bodies are still growing—chemotherapy and radiation treatments can cause lifelong damage. Now, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have reported that a targeted therapy that blocks a prot...

– Sanford Burnham Prebys Medical Discovery Institute

R01CA159859; F31NS086367; LT00432/2014; LA1-01747; #01KU1505G; Nature Communications

New findings may help oncologists determine effectiveness of checkpoint inhibitors

In an article recently published in JCI Insight, researchers from the University of Alabama at Birmingham and Vanderbilt University have identified checkpoint inhibitor resistance mechanisms in many solid tumor cancers, including melanoma, lung cance...

– University of Alabama at Birmingham

JCI Insight

Study Shows Low-Sugar Diet Effective in Boys with Nonalcoholic Fatty Liver Disease

Researchers at University of California San Diego School of Medicine found that a diet low in free sugars (those added to foods and beverages and occurring naturally in fruit juices) resulted in significant improvement in nonalcoholic fatty liver dis...

– University of California San Diego Health



National Comprehensive Cancer Network Updates Resources for Improving Cancer Care in the Middle East & North Africa

The National Comprehensive Cancer Network® (NCCN®) has published updated resources for improving and facilitating quality, effective, efficient, and accessible cancer care in the Middle East and North Africa (MENA).

– National Comprehensive Cancer Network® (NCCN®)

Embargo expired on 29-Jan-2019 at 08:00 ET

GW Cancer Researchers Investigate Nanoimmunotherapies for Cancer

A team at GW Cancer Center is investigating Prussian blue nanoparticles used in combination with checkpoint inhibitors for cancer treatment

– George Washington University

Rowan University announces $3+ million in funding for research in Camden

Rowan University, Glassboro, New Jersey, has announced the first grants of the Camden Health Research Initiative, a $50 million pledge by the University to fund research in and/or impacting the City of Camden during the next 10 years.

– Rowan University

Announcing the 2018 SLAS Technology Ten: Translating Life Sciences Innovation

The SLAS Technology Ten annually showcases ten individual articles that stand out as the most innovative scientific achievements published in SLAS Technology in the past 12 months.

– SLAS (Society for Laboratory Automation and Screening)

The 2019 SLAS Technology Ten

Exploring Targeted Therapy for Non-Small Cell Lung Cancer

Rutgers Cancer Institute of New Jersey researcher Sharon R. Pine, PhD, has received a $200,000 Lung Cancer Discovery Award from the American Lung Association to examine potential new treatment options for patients with a sub-type of non-small cell lu...

– Rutgers Cancer Institute of New Jersey

Major Grant to Bolster Research on Inflammation-Related Cancers

Cancer Research UK has awarded a 20-million-pound grant (about $26 million U.S.) to a team of international investigators, including Vanderbilt’s James Goldenring, MD, PhD, to study inflammation-related cancers.

– Vanderbilt University Medical Center

Higher Education Events

Lobos Love Pink Week

The University of New Mexico Men’s and Women’s basketball teams hope to see a sea of pink in support of breast cancer fighters and survivors at their Lobos Love Pink games in February. The games help to raise awareness for the disease and for bre...

– University of New Mexico Comprehensive Cancer Center





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