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Newswise Special Wire
Tuesday, February 5, 2019

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Newswise Cancer Research Wire for 05-Feb-2019

Study links protein, clusterin, to cardiac and metabolic diseases

During a study spanning nearly a decade, researchers at The Ohio State University College of Medicine, Houston Methodist Research Institute and Houston Methodist Cancer Center have linked the protein clusterin – for the first time -- to many diffe...

– Houston Methodist

Diabetes Care

Drug target identified for chemotherapy-resistant ovarian, breast cancer

Researchers at Washington University School of Medicine in St. Louis may have found a path toward improving the effectiveness of chemotherapy in people with breast or ovarian cancer caused by defects in one of the BRCA genes. The researchers identifi...

– Washington University in St. Louis

J Cell Biol, Feb-2019; R01 CA118487; R01 GM108648; R01 CA193318; MC-II- 2015-453; BC151728

Potential to Better Treat Mesothelioma Revealed by Precision Medicine Research

Researchers have successfully identified two genetic markers for potentially effective treatment of Mesothelioma, an orphan disease most commonly associated with asbestos exposure, and for which few treatments exist.

– Sbarro Health Research Organization (SHRO)

International Journal of Molecular Sciences

New Study Shows Cost Effectiveness of Early Cancer Surveillance for Patients Who Have a High Risk of Developing Cancer

New research published today in the journal Pediatric Blood and Cancer shows how early cancer screening and surveillance in patients with Li-Fraumeni Syndrome (LFS) results in additional years of life, and is cost effective for third-party payers.

– Huntsman Cancer Institute at the University of Utah

Pediatric Blood and Cancer

Thyroid cancer incidence associated with malpractice climate

The incidence of thyroid cancer was associated with malpractice payouts in a recent study by Penn State Cancer Institute researchers. Because thyroid cancer is not usually fatal, the findings suggest that physicians sometimes offer unnecessary testin...

– Penn State Health


Wolters Kluwer to Publish Journal of Psychosocial Oncology Research and Practice

Wolters Kluwer, Health announced today that the Journal of Psychosocial Oncology Research & Practice, the newest journal of the International Psycho-Oncology Society (IPOS), will be published under the Lippincott portfolio.

– Wolters Kluwer Health: Lippincott Williams and Wilkins

Journal of Psychosocial Oncology Research and Practice

MD Anderson supports World Cancer Day call for action to end cancer

As an institution devoted to eliminating cancer for patients in Texas, the nation and around the world, The University of Texas MD Anderson Cancer Center is proud to uphold the mission of World Cancer Day, Feb.4, to unite the global population toward...

– University of Texas M. D. Anderson Cancer Center

A New Toolkit For Studying How "PARP" Activity Boosts Cancers

A new method developed by scientists at Johns Hopkins Bloomberg School of Public Health is likely to speed the study of an important biological process called ADP-ribosylation.

– Johns Hopkins Bloomberg School of Public Health

Molecular Cell

Leaders meet in Colorado to set research agenda for early-onset colorectal cancer

While overall rates of colorectal cancer are down, the rate of young people getting the disease is up 22 percent over two decades. International leaders meet in Colorado to set the research agenda to figure out why.

– University of Colorado Cancer Center

Fight Colorectal Cancer's (CRC) Early Age Onset Workshop

Tip Sheet: Advances in understanding breast cancer metastasis; how to boost clinical trial participation; and a new approach to looking at HIV

Summaries of recent Fred Hutch research.

– Fred Hutchinson Cancer Research Center

Commonly Used Anti-Rejection Drug Could be Repurposed to Treat Some Liver Cancers

Research in animal models suggest that liver cancers with a mutation in the β-catenin gene could respond to treatment with rapamycin, a commonly used immunosupressant.

– Health Sciences at the University of Pittsburgh

Cell Metabolism

Embargo expired on 31-Jan-2019 at 11:00 ET

Cell lines deserve unique considerations when creating research protections, authors say

New rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But this rule could have unintended consequences for certain critical types of biospecimens.

– Michigan Medicine - University of Michigan

JAMA Oncology; DE025184; CA194536

Embargo expired on 31-Jan-2019 at 11:00 ET

Opposite Effect: Protein Widely Known to Fight Tumors Also Boosts Cancer Growth

UC San Diego researchers studying p53, the heralded cancer-fighting “guardian of the genome,” have found that the human protein also plays a role in promoting tumors, in addition to suppressing them.

– University of California San Diego

Cancer Cell, Jan-2019

Embargo expired on 31-Jan-2019 at 11:00 ET

High-dose radiation therapy improves long-term survival in patients with stage-IV cancers, trial finds

The first report from a phase II, multi-center clinical trial indicates that a newer, more aggressive form of radiation therapy — stereotactic radiation — can extend long-term survival for some patients with stage-IV cancers while maintaining the...

– American Society for Radiation Oncology (ASTRO)

International Journal of Radiation Oncology*Biology*Physics, Jan-2019

NUS study: Nanoparticles may promote cancer metastasis

Researchers from the National University of Singapore have found that cancer nanomedicine, which are designed to kill cancer cells, may accelerate metastasis. Using breast cancer as a model, they discovered that common nanoparticles made from gold, t...

– National University of Singapore

Nature Nanotechnology

BIDMC's Research & Health News Digest - January 2019 Edition

A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.

– Beth Israel Deaconess Medical Center

Many Women Get Unnecessary Mammograms Before Breast Reduction Surgery

Getting a mammogram before breast reduction surgery is not required or recommended. But thousands of young women with no known breast cancer risk still get them, a Michigan Medicine study shows.

– Michigan Medicine - University of Michigan

JAMA Surgery

FSU Team Breaks New Ground in Study of Malignant Pediatric Brain Tumor

FSU researchers identified a series of cancer-causing driver gene mutations and discovered that medulloblastoma is perhaps an even more dynamic and variable tumor than expected.

– Florida State University

Journal of Cancer

Good Results with Autologous Breast Reconstruction after Failed Implant Reconstruction

Implants are usually the first choice for breast reconstruction after mastectomy. But when implant-based reconstruction fails, autologous reconstruction – using the patient's own tissues – is a safe procedure that improves patient outcomes, repor...

– Wolters Kluwer Health: Lippincott Williams and Wilkins

Plastic and Reconstructive Surgery

MSK Researchers Identify a New Method to “Genetically Cloak” Cancer-Fighting Immune Cells

During cancer immunotherapy, immune cells often undergo a form of cellular suicide, termed apoptosis, which can limit the therapy’s effectiveness.

– Memorial Sloan Kettering Cancer Center

Journal of Clinical Investigation

Policy and Public Affairs

More than 60 Leading Health Care Organizations Call on CMS to Maintain Coverage for Medically Necessary Cancer Testing

Leading health care companies and organizations representing patients, providers, academic medical centers, laboratories, and diagnostic manufacturers urged the Centers for Medicare and Medicaid Services to revise its interpretation of the National C...

– Association for Molecular Pathology


On World Cancer Day, National Comprehensive Cancer Network Announces National Endorsements for Guidelines to Improve Cancer Care in Sub-Saharan Africa

The National Comprehensive Cancer Network® (NCCN®) announces formal endorsements from the governments of Ethiopia, Nigeria, and Tanzania for the NCCN Harmonized Guidelines™ for Sub-Saharan Africa, while joining cancer leaders across the globe to ...

– National Comprehensive Cancer Network® (NCCN®)

Embargo expired on 04-Feb-2019 at 00:05 ET

Dr. Prateek Sharma Named President of International Society for Diseases of the Esophagus

Prateek Sharma, MD, gastroenterologist and member of The University of Kansas Cancer Center, has been named president of The International Society for Diseases of the Esophagus (ISDE). The ISDE is a multidisciplinary international organization compri...

– University of Kansas Cancer Center

Research Network Co-Chaired by Experts from RTI International, CDC and University of Illinois at Chicago Releases Collection of Articles on Non-Communicable Diseases

The International NCD Economics Research Network, a network of economists co-chaired by the independent, nonprofit research institute RTI International, the U.S. Centers for Disease Control and Prevention (CDC) and the University of Illinois at Chica...

– RTI International

Translating Patient Feedback Into Better Cancer Treatments

New experimental cancer treatments are raising hopes among clinicians and patients for longer survival times and cures. But clinical trials that test such treatments also need to analyze the impact on patients of potentially harsh side effects, known...

– Cedars-Sinai

National Cancer Institute of the National Institutes of Health under Award Number U01CA232859

UNM Cancer Center Offers Mohs Surgery

Newly opened outpatient surgical suites at The University of New Mexico Comprehensive Cancer Center have enabled the addition of another set of treatments to its arsenal: Mohs surgery. Mohs surgery has the highest cure rate of all skin cancer surgeri...

– University of New Mexico Comprehensive Cancer Center

Minoff Family makes visionary gift to University Hospitals

The Minoff Family of Northeast Ohio has made a generous gift to the University Hospitals system. In their honor, UH will rename one of its health centers to the Minoff Health Center at Chagrin Highlands.

– University Hospitals Cleveland Medical Center

Expert Pitch

Myositis experts available to talk about Myositis during Rare Disease Month

– Myositis Association

Big fat lies about obesity: ASU professor says health risks of obesity have been exaggerated

– Arizona State University (ASU)





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