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Newswise Special Wire
Tuesday, February 26, 2019

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Newswise Cancer Research Wire for 26-Feb-2019

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Cancer Survivors See Mostly Positives in How They Have Changed

Two years after diagnosis, breast cancer survivors have four times more positive than negative thoughts about changes they experienced because of their illness, a new study found.

– Ohio State University

Health Psychology

A Single Dose of a PD-1 Inhibitor Before Surgery Predicts Outcomes in Melanoma Patients

A single dose of a PD-1 inhibitor before surgery for melanoma can put patients in remission.

– Perelman School of Medicine at the University of Pennsylvania

Nature Medicine; P50-CA174523; P01-CA114046; T32-2T32CA009615; P30 CA016520; AI105343; AI108545; 623 AI117950; AI082630; CA210944; AI114852...

Embargo expired on 25-Feb-2019 at 11:00 ET

Breakthrough 'Lab-on-a-Chip' Detects Cancer Faster, Cheaper and Less Invasively

A new ultrasensitive diagnostic device invented by researchers at the University of Kansas, The University of Kansas Cancer Center and KU Medical Center could allow doctors to detect cancer quickly from a droplet of blood or plasma, leading to timeli...

– University of Kansas Cancer Center

Nature Biomedical Engineering; P30 CA168524; CA1806846; CA214333

Embargo expired on 25-Feb-2019 at 11:00 ET

Supplying High-Quality Cancer-Imaging Isotopes

New method produces high-purity zirconium-89, a diagnostic radionuclide used to image cancerous tumors.

– Department of Energy, Office of Science

Applied Radiation and Isotopes 122, 211 (2017). [DOI: 10.1016/j.apradiso.2017.01.037]; Applied Radiation and Isotopes 132, 85 (2018). [DOI: 10.1016/j.apradiso.2017.10.048]; Journal of Chromatography A 1545, 48 (2018). [DOI: 10.1016/j.chroma.2018.02.053]...

ACA Medicaid Expansion Shows Impact on Colon Cancer Screenings, Survival in Ky.

A new University of Kentucky study published in the Journal of the American College of Surgeons shows a direct link between the adoption of the Affordable Care Act (ACA) Medicaid expansion and the impact of colon cancer on Kentuckians.

– University of Kentucky

Journal of the American College of Surgeons

A New Sequencing Method to Detect DNA Modifications of Relevance to Cancer

Ludwig Cancer Research scientists report in the current issue of Nature Biotechnology a new and improved method to detect chemical modifications to DNA. These modifications—or “epigenetic” marks—help control gene expression and their aberrant...

– Ludwig Cancer Research

Nature Biotechnology, Feb-2019

UVA Discovers How to Make Immune Cells Better Cancer Killers

Scientists have discovered a defect in immune cells known as “killer T cells” that explains their inability to destroy cancer tumors. The researchers believe that repairing this defect could make the cells much better cancer killers.

– University of Virginia Health System

Science Immunology, Jan. 2019; R01CA166458-03S1; R01CA166458; R01DK105550; R01CA217987

Lab-grown mini tumors could help identify personalized treatments for people with rare cancers

UCLA scientists have developed a new method to quickly screen hundreds of drugs in order to identify treatments that can target specific tumors.

– University of California, Los Angeles (UCLA), Health Sciences

Communications Biology

Mayo Clinic Researchers Identify Gene That May Predict Pancreatic Cancer in People with Type 2 Diabetes

Mayo Clinic researchers have identified a gene called “UCP-1” that may predict the development of pancreatic cancer in people with Type 2 diabetes. Their findings are published in Gastroenterology.

– Mayo Clinic


New Microfluidics Device Can Detect Cancer Cells in Blood

Researchers at the University of Illinois at Chicago and Queensland University of Technology of Australia, have developed a device that can isolate individual cancer cells from patient blood samples. The microfluidic device works by separating the va...

– University of Illinois at Chicago

Microsystems & Nanoengineering

Older Biologic Age Linked to Elevated Breast Cancer Risk

Biologic age, a DNA-based estimate of a person’s age, is associated with future development of breast cancer, according to scientists at the National Institutes of Health. If a woman’s biologic age was older than her chronologic age, she had a 15...

– National Institute of Environmental Health Sciences (NIEHS)

Journal of the National Cancer Institute; ZIAES049033; ZIAES049032; ZIAES044005

Medicaid expansion in Kentucky led to an increase in screening and improved survival for colorectal cancer patients

The number of low-income patients screened for colorectal cancer more than tripled after Medicaid expansion in 2014, according to study findings in the Journal of the American College of Surgeons.

– American College of Surgeons (ACS)

Journal of the American College of Surgeons; 130th Annual Meeting of the Southern Surgical Association, December 2018; NCI HHSN26100001; CDC U58 DP005400; NCI P30 CA177558...

PET Scans Show Biomarkers Could Spare Some Breast Cancer Patients from Chemotherapy

Roisin Connolly, M.B.B.Ch., M.D., associate professor of oncology Credit: Johns Hopkins Kimmel Cancer Center

– Johns Hopkins Medicine

P30-CA006973, 5U01CA140204; Journal of Clinical Oncology

New “Interspecies Communication” Strategy between Gut Bacteria and Mammalian Hosts Uncovered

Bacteria in the gut do far more than help digest food in the stomachs of their hosts, they can also tell the genes in their mammalian hosts what to do. A study published today in Cell describes a form of “interspecies communication” in which bact...

– Case Western Reserve University


Roswell Park Presentations at TCT 2019 Focus on Tools for Predicting Patient Outcomes

Several Roswell Park Comprehensive Cancer Center experts were invited to highlight research and best practices during the TCT/Transplantation and Cellular Therapy Meetings now underway in Houston, Texas.

– Roswell Park Comprehensive Cancer Center


American Academy of Dermatology Association Comments on FDA Proposed Sunscreen Rule

Because sunscreen is an important tool in the fight against skin cancer, the AADA supports any and all regulations to ensure that the public has access to safe and effective sunscreens.

– American Academy of Dermatology

CASSINI Trial publishes data on preventing blood clots in cancer patients

The first clinical study investigating the use of the direct oral anticoagulant, rivaroxaban, to prevent blood clots in patients with cancer at high-risk published today in the New England Journal of Medicine. The study found no significant reduction...

– Fred Hutchinson Cancer Research Center

New England Journal of Medicine

Embargo expired on 20-Feb-2019 at 17:00 ET

Integrating Heart Disease and Cancer Care Could Reduce Overall Health Care Costs, According to Researchers

Study in JNCCN finds coronary artery disease costs increase dramatically in patients who are diagnosed with cancer.

– National Comprehensive Cancer Network® (NCCN®)

JNCCN—Journal of the National Comprehensive Cancer Network

Study finds melanoma brain metastases are immunosuppressive with treatment-resistant metabolism

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites. Researchers at The University of Texas MD Anderson Cancer Center report in Cancer Discover...

– University of Texas M. D. Anderson Cancer Center

New compound could help treat ovarian cancer

Scientists from the University of Sheffield have discovered a compound that could be more effective in treating certain cancers than standard chemotherapy.

– University of Sheffield

Journal of the American Chemical Society

New Method to Detect Cancer Cells Faster, Potentially Improving Outcomes

The days - or even weeks - spent waiting for the results of a cancer-screening test can feel like an eternity. Especially when early diagnosis and quick action are tied to better outcomes.

– Purdue University

ACS Combinatorial Science

Four myths about colorectal cancer debunked

Colorectal cancer is one of the most common cancers in both men and women – but it needn’t be. Oncologist Zev Wainberg, MD, debunks four common myths about the disease.

Expert Available

– University of California, Los Angeles (UCLA), Health Sciences

T-cell receptor diversity may be key to treatment of follicular lymphoma, Mayo study finds

Healthy white blood cells, called “T-cells,” play a crucial role in how the body fights follicular lymphoma. That's according to the results of a study led by Mayo Clinic hematologists Zhi Zhang Yang, M.D., and Stephen Ansell, M.D., Ph.D., that w...

– Mayo Clinic

Cell Reports

Yale Cancer Center researchers combine targeted therapies to fight head and neck cancers

Yale Cancer Center researchers have identified a potential therapy that combines two types of molecularly targeted drugs to produce a synergistic effect against head and neck cancer.

– Yale Cancer Center

Clinical Care Research


Fight Colorectal Cancer breaks down barriers to colorectal cancer screening

During March 2019 - Colorectal Cancer Awareness Month - the leading advocacy organization is rallying advocates to raise awareness so all Americans can access life-saving colorectal cancer screenings.

– Fight Colorectal Cancer

Nearly $20 million awarded by CPRIT to MD Anderson

MD Anderson received nearly $20 million from CPRIT for research, recruitment and prevention. The awards represented 20 percent of the $96 million CPRIT awarded this time. Since its inception, CPRIT has awarded $ 447.6 million to MD Anderson.

– University of Texas M. D. Anderson Cancer Center

Hospital staff, community to go bald for cancer research

The Children’s Hospital University of Illinois will host an annual head-shaving event to raise money for the St. Baldrick’s Foundation on Feb. 22.

– University of Illinois at Chicago

Higher Education Events

Playing Hoops to Battle Cancer

Legislators battle cancer in annual Hoops 4 Hope basketball game. The legislators enjoy playing, the spectators enjoy the show, and the annual game raises money to help people in New Mexico diagnosed with cancer.

– University of New Mexico Comprehensive Cancer Center





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