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Newswise Special Wire
Tuesday, March 5, 2019

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Newswise Cancer Research Wire for 05-Mar-2019

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

New ORNL AI tool revolutionizes process for matching cancer patients with clinical trials

A team of researchers from the Department of Energy’s Oak Ridge National Laboratory (ORNL) Health Data Sciences Institute (HDSI) have harnessed the power of artificial intelligence (AI) to better match cancer patients with clinical trials. The rese...

– Oak Ridge National Laboratory

How A Common Oral Bacteria Makes Colon Cancer More Deadly

New research reveals how a bacteria in dental plaque-- involved in 1/3 of colon cancer cases-- speeds up colon cancer growth and makes the disease more deadly.

– Columbia University Irving Medical Center

EMBO Reports

Embargo expired on 04-Mar-2019 at 06:00 ET

Promising Strategy to Fight the Most Deadly Brain Tumor in Children

A study published in Nature Communications found that an inhibitor of an enzyme called ACVR1 slows tumor growth and increases survival in an animal model of diffuse intrinsic pontine glioma (DIPG) – the most deadly brain tumor in children. Currentl...

– Ann and Robert H. Lurie Children's Hospital of Chicago

Nature Communications, March-2019

Embargo expired on 04-Mar-2019 at 05:00 ET

Genomics Could Better Match Treatments to Pancreatic Cancer Patients

Largest ever study of pancreatic cancer genomics uncovers a way to match chemotherapy drugs to patients

– Health Sciences at the University of Pittsburgh


Embargo expired on 04-Mar-2019 at 07:00 ET

Potential treatment strategy uncovered for pancreatic cancer

Findings published in Nature Medicine lead to clinical trials

– University of North Carolina Health Care System

Nature Medicine, March-2019

Embargo expired on 04-Mar-2019 at 11:00 ET

Bundle Payment Model Analysis of Emerging Breast Cancer Screening

Bundled payments have been touted as mechanisms to optimize quality and costs. A prior feasibility study evaluating bundled payments for screening mammography episodes predated widespread adoption of digital breast tomosynthesis (DBT).

– Harvey L. Neiman Health Policy Institute

Journal of the American College of Radiology (JACR)

Researchers develop mini kidneys from urine cells

Scientists from Utrecht University, University Medical Center Utrecht and Hubrecht Institute have successfully created kidney organoids from urine cells.

– Utrecht University

Nature Biotechnology

Promising New Pancreatic Cancer Treatment Moves Forward

A study published today in the journal Nature Medicine led by researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) describes a new therapeutic approach with potential for patients with pancreatic cancer. These researchers...

– University of Utah

CAR-T Cell Therapy Available at Rutgers Cancer Institute of New Jersey and Robert Wood Johnson University Hospital

Those with B-cell lymphomas that do not respond to standard therapies now have another treatment option in New Jersey, as CAR-T cell therapy is now being offered at Robert Wood Johnson University Hospital New Brunswick, an RWJBarnabas Health facility...

– Rutgers Cancer Institute of New Jersey

Smokers Often Misunderstand Health Risks of Smokeless Tobacco Product, Rutgers Study Finds

“Snus” may be less harmful for smokers unable or unwilling to quit tobacco

– Rutgers University-New Brunswick

Journal of Addictive Behaviors

Researchers develop techniques to track the activity of a potent cancer gene in individual cells

Researchers at the National Cancer Institute use novel tools to reveal that cancer gene MYC causes global changes in gene activation, with subtle differences between individual cells

– Biophysical Society

63rd Biophysical Society Annual Meeting. March 2 - 6, 2019

Embargo expired on 01-Mar-2019 at 06:00 ET

A highly sensitive new blood test can detect rare cancer proteins

Researchers at Johns Hopkins University developed a new blood test that can identify proteins-of-interest down to the sub-femtomolar range with minimal errors

– Biophysical Society

63rd Biophysical Society Annual Meeting. March 2 - 6, 2019

Embargo expired on 01-Mar-2019 at 09:00 ET

Researchers search for solutions to ‘invisible threat’ that affects cancer care workers

A study from the University of Michigan Rogel Cancer Center sought to improve nurses’ handling of chemotherapy by delivering an educational intervention with quarterly reminders and tailored messages. But despite the strong study design and quality...

– Michigan Medicine - University of Michigan

Oncology Nursing Forum; R01 OH010582-01

Shedding Light—Literally—on Resistance to Radiation Therapy

A new Johns Hopkins study offers promise towards someday being able to non-invasively examine changes in cancerous tumors to determine whether they’ll respond to radiation treatment, before treatment even begins.

– Johns Hopkins University

Cancer Research- Feb-2019; 2-P41-EB015871-31; DP2GM128198; P20GM103625

Embargo expired on 28-Feb-2019 at 10:00 ET

An Atlas of an Aggressive Leukemia

A team of researchers led by Bradley Bernstein at the Ludwig Center at Harvard has used single-cell technologies and machine learning to create a detailed “atlas of cell states” for acute myeloid leukemia (AML) that could help improve treatment o...

– Ludwig Cancer Research

Cell, Feb-2019

Embargo expired on 28-Feb-2019 at 11:00 ET

How Prostate Cancer Becomes Treatment Resistant

Scientists from Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified how prostate cancer transforms into a deadly treatment-resistant subtype following treatment with anti-androgen therapy. Their findings—which include the metab...

– Sanford Burnham Prebys Medical Discovery Institute

Cancer Cell; R01CA192642; R01CA218254; R01DK108743; R01CA211794

Embargo expired on 28-Feb-2019 at 11:00 ET

Investigadores de Mayo Clinic identifican gen que predeciría cáncer pancreático en diabéticos tipo 2

Los investigadores de Mayo Clinic identificaron un gen llamado UCP-1 que predice la aparición del cáncer pancreático en personas con diabetes tipo 2. Los resultados se publican en Gastroenterology.

– Mayo Clinic


To Beat Cancer, You’ve Got to Have Heart

When it comes to lifestyle changes that can help people avoid cancer, it turns out the heart has a lot to say on the matter.

– Perelman School of Medicine at the University of Pennsylvania

Liquid biopsy as effective as tissue biopsy for non-small cell lung cancer according to MD Anderson study

A multi-center study led by researchers at The University of Texas MD Anderson Cancer Center revealed that a liquid biopsy test called Guardant360®, is comparable to standard tissue biopsies in detection of guideline recommended biomarkers in advanc...

– University of Texas M. D. Anderson Cancer Center

AACR Annual Meeting 2019, March 29-April 3

Embargo expired on 27-Feb-2019 at 16:30 ET

Muscle Gene Mutations Implicated in Human Nasal/Sinus Cancer

By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic changeone in a gene involved in muscle formationin five o...

– Johns Hopkins Medicine

Nature Communications; 2014107, P50- CA062924

Newly Identified Drug Targets Could Open Door for Esophageal Cancer Therapeutics

Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma (EAC), the most common esophageal malignancy in the United States, according to new research out of Case Western Reserve University School...

– Case Western Reserve University


Inhibiting Cancer-Causing Protein Could Prevent Scleroderma Fibrosis

Examining the autoimmune disease at the molecular level led researchers to a specific molecule that could be contributing to the disease progression in patients.

– Michigan Medicine - University of Michigan

Proceedings of the National Academy of Sciences

White Shark Genome Decoded

SEASIDE, Ca., February 25, 2019 – An international team of researchers, that includes CSUMB School of Natural Sciences assistant professor Nathaniel Jue, has published a major scientific step to understanding the biology of the great white shark, a...

– California State University, Monterey Bay

Proceedings of the National Academy of Sciences

Antibodies on nanoparticle surfaces may foster or fluster therapies

For nanomedicine to achieve the envisioned breakthroughs in disease treatment, scientists must learn why the immune system often responds inhospitably to these therapies. An NIH-funded team at the University of Colorado (UC) has assembled a clearer p...

– National Institute of Biomedical Imaging and Bioengineering

Nature Nanotechnology; EB022040; CA194058; CA174560


New center addresses alarming increase in colorectal cancer rates among young adults

Dana-Farber/Brigham and Women's Cancer Center announced the launch of the Young-Onset Colorectal Cancer Center. The center will provide expert, compassionate and cutting-edge care to young adult colon and rectal cancer patients with a focus on scient...

– Dana-Farber Cancer Institute

NCCN 2019 Annual Conference Includes Focus on Patient Experience with Innovative Therapies, Plus Updates on Biomarkers, Biosimilars, and the Latest Research on Cancer Care

More than 1,500 cancer care professionals are meeting in Orlando, Florida, March 21-23, for the NCCN 2019 Annual Conference, presented by the National Comprehensive Cancer Network® (NCCN®)—an alliance of 28 leading cancer centers.

– National Comprehensive Cancer Network® (NCCN®)

Dana-Farber Opens Center for the Prevention of Progression Clinic

Dana-Farber Cancer Institute opens Center for the Prevention of Progression clinic to focus on precursor conditions in blood cancers

– Dana-Farber Cancer Institute

Henry Ford Health System Names New Chair of Urology Department

Henry Ford Health System has appointed Craig Rogers, M.D. the new chair of its Department of Urology, effective April 1, 2019.

– Henry Ford Health System

New Patient Resource from NCCN Clears up Confusion around Highly Common Type of Skin Cancer

New NCCN Guidelines for Patients: Squamous Cell Skin Cancer explains risk factors and treatment options for cancer type that impacts millions every year.

– National Comprehensive Cancer Network® (NCCN®)

Cancer Research Advocates Cam and Wanda Garner Give $2 Million to Endow Faculty Chair at UC San Diego Moores Cancer Center

Pharmaceutical leader Cam Garner and his wife Wanda, a cancer workshop facilitator and philanthropic fundraiser, gave UC San Diego $2 million to establish the Garner Family Chancellor’s Endowed Chair in Blood and Marrow Transplant.

– University of California San Diego





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