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Newswise Special Wire
Tuesday, March 26, 2019

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Newswise Cancer Research Wire for 26-Mar-2019
 

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.


Cancer Research


Study Shows That Patients With or Without Cancer Use Different Forms of Marijuana

People with and without cancer are more likely, over time, to use a more potent form of medical marijuana with increasingly higher amounts of tetrahydrocannabinol (THC), a new study shows.

– NYU Langone Health

Journal of Palliative Medicine

Embargo expired on 26-Mar-2019 at 00:05 ET


Time-restricted eating may help prevent breast cancer, mouse study suggests

Changing when you eat rather than what you eat may prove to be a dietary intervention against breast cancer, suggests a new mouse study to be presented Saturday at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.

– Endocrine Society

ENDO 2019, Mar-2019

Embargo expired on 25-Mar-2019 at 09:00 ET


Breast Cancer May Be Likelier to Spread to Bone with Nighttime Dim-Light Exposure

Exposure to dim light at night, which is common in today’s lifestyle, may contribute to the spread of breast cancer to the bones, researchers have shown for the first time in an animal study. Results of the study will be presented Saturday at ENDO ...

– Endocrine Society

ENDO 2019, March 23-26

Embargo expired on 23-Mar-2019 at 14:00 ET


Mailing Colorectal Cancer Screening Kits Found Effective, Regardless of Financial Incentive

Roughly a quarter of patients overdue for colorectal cancer screening mailed completed screening kits back within two months, whether or not they were given a financial incentive to do so.

– Perelman School of Medicine at the University of Pennsylvania

JAMA Network Open; K08CA234326; R01CA213645

Embargo expired on 22-Mar-2019 at 11:00 ET


Researchers Restore Fertility in Non-Human Primate Model of Childhood Cancer Survivorship

In a first, researchers at the University of Pittsburgh School of Medicine and the Magee-Womens Research Institute have reported in a non-human primate model that immature testicular tissue can be cryopreserved, and later be used to restore fertility...

– Health Sciences at the University of Pittsburgh

Science; P01HD075795, R01 HD076412, HD076412, P51OD011092

Embargo expired on 21-Mar-2019 at 14:00 ET


Topical immunotherapy keeps skin cancer risk at bay

A combination of two topical creams already shown to clear precancerous skin lesions from sun-damaged skin also lowers the risk that patients will later develop squamous cell carcinoma of the skin, according to a new study.

– Washington University in St. Louis

JCI Insight, Mar-2019; K08AR068619; DP5OD0213530

Embargo expired on 21-Mar-2019 at 09:00 ET


Mount Sinai and IBM Researchers Uncover Key to Greater Efficacy in Cancer Treatment

Mitochondria are found to be associated with the effectiveness of oncological drug therapies

– Mount Sinai Health System

Nature Communications - March-2019

Embargo expired on 21-Mar-2019 at 06:00 ET


MD Anderson study points to new strategy for boosting immunotherapy effectiveness in advanced colorectal cancer

Researchers at The University of Texas MD Anderson Cancer Center revealed the common oncogene KRAS as a possible explanation for why many patients with metastatic colorectal cancer (CRC) do not respond to immune checkpoint blockade (ICB) therapy.

– University of Texas M. D. Anderson Cancer Center

Cancer Cell

Embargo expired on 21-Mar-2019 at 11:00 ET


Neutrons paint atomic portrait of prototypical cell signaling enzyme

Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neu...

– Oak Ridge National Laboratory

Gerlits et al., Sci. Adv., 2019; 5: eaav0482

Embargo expired on 20-Mar-2019 at 14:00 ET


Tumor-associated immune cells hinder frontline chemotherapy drug in pancreatic cancer

A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug’s action, research led by the University of Michigan Rogel Cancer Cente...

– Michigan Medicine - University of Michigan

Cell Metabolism


Immune Cells Age and Die Prematurely in People With Very Short Telomeres, According to New Study

Scientists at Johns Hopkins say they have found that people born with abnormally short chromosome endcaps, or telomeres, have immune system cells that age and die prematurely. Their short-lived immune system cells also share some of the same characte...

– Johns Hopkins Medicine

The Journal of Clinical Investigation


MD Anderson study may explain why immunotherapy not effective for some patients with metastatic melanoma and kidney cancer

White blood cells known as B cells have been shown to be effective for predicting which cancer patients will respond to immune checkpoint blockade (ICB) therapy, according to a study at The University of Texas MD Anderson Cancer Center. Study results...

– University of Texas M. D. Anderson Cancer Center

AACR Annual Meeting 2019, March 29-April 3


Understanding gene interactions holds key to personalized medicine, scientists say

When the Human Genome Project was completed, in 2003, it opened the door to a radical new idea of health - that of personalized medicine, in which disease risk and appropriate treatment would be gleaned from one's genetic makeup. As more people had t...

– University of Toronto

Cell


Can you 'catch' cancer?

Billions worldwide are infected with tropical worms. Unsurprisingly, most of these people live in poor countries, kept poor by the effects of worm-related malnourishment.

– Frontiers

Frontiers in Medicine


A protein’s surprising role offers clues to limit graft-vs.-host disease

In a surprising finding, researchers at the University of Michigan Rogel Cancer Center showed the protein NLRP6 aggravated the difficult symptoms of gastrointestinal graft-vs.-host disease. Knocking out this protein in mice led to significantly bette...

– Michigan Medicine - University of Michigan

Nature Microbiology; AI-075284; HL-090775


Female radiation oncologists submit fewer charges to Medicare, collect less revenue, study finds

A new study by UCLA researchers has found that female radiation oncologists submit fewer charges to Medicare, are reimbursed less per charge submitted and receive lower Medicare payments overall in comparison to male radiation oncologists.

– University of California, Los Angeles (UCLA), Health Sciences

JAMA Network Open


Collaboration Aims to Reduce Racial and Ethnic Disparities in Clinical Trials

Spencer Hoover, vice president and executive director of the Henry Ford Cancer Institute, is co-author of a manuscript published in the Journal of Oncology Practice aimed at establishing best practices to promote diversity in clinical trials. In-dept...

– Henry Ford Health System

Journal of Oncology Practice, March-2019


New Drug Combination Shows Promise for Common Pediatric Brain Tumor

A new combination treatment aimed at resistant and recurrent low-grade gliomas slowed tumor growth and killed tumor cells in laboratory and mouse models.

– Johns Hopkins Medicine

Neuro-Oncology


How ‘Sleeper Cell’ Cancer Stem Cells Are Maintained in Chronic Myelogenous Leukemia

While chronic myelogenous leukemia is in remission, ‘sleeper cell,’ quiescent leukemic stem cells persist in the bone marrow. Researchers find that niche-specific expression of chemokine CXCL12 by mesenchymal stromal cells controls quiescence of ...

– University of Alabama at Birmingham

Cell Stem Cell; CA172447 ; CA033572


UTSW researchers identify new mechanism to reduce inflammation

UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection.

– UT Southwestern Medical Center

Nature


Study: Protein Linked to Cancer Growth Drives Deadly Lung Disease

A protein associated with cancer growth appears to drive the deadly lung disease known as idiopathic pulmonary fibrosis, according to new research from Cedars-Sinai. The discovery, made in laboratory mice and human tissue samples, may have implicatio...

– Cedars-Sinai

JCI Insight, March 21, 2019


Drinking hot tea linked with elevated risk of esophageal cancer

Previous studies have revealed a link between hot tea drinking and risk of esophageal cancer, but until now, no study has examined this association using prospectively and objectively measured tea drinking temperature. A new International Journal of ...

– Wiley

International Journal of Cancer


UCLA Researchers Identify Potential New Combination Treatment for Pancreatic Cancer

Researchers from UCLA’s Jonsson Comprehensive Cancer Center have identified a possible new therapeutic strategy using two types of drug inhibitors at once to treat one of the world’s deadliest cancers.

– University of California, Los Angeles (UCLA), Health Sciences


Precision Oncology Insights Revealed for Colorectal Cancer

Findings published in the Journal of Clinical Oncology could help define strategies to more effectively treat colorectal cancer, the second leading cause of cancer death in the United States.

– University of North Carolina Health Care System

Journal of Clinical Oncology, March-2019


Cancer Experts and Features


The Medical Minute: Which colorectal cancer screening do I need?

March is Colorectal Cancer Awareness Month, and the Colorectal Cancer Alliance is urging everyone to talk with their health care providers about screening.

– Penn State Health


Fred Hutch at AACR: NextGen star, liquid biopsies, immunotherapy, cancer genetics, health disparities and more

Fred Hutchinson Cancer Research Center’s latest findings in immunotherapies, nanoparticles to deliver gene therapy, the genetic underpinnings of cancer, insights on health disparities and more will be showcased at the annual meeting of the American...

– Fred Hutchinson Cancer Research Center


Robots Improve Cancer Surgery

Victor Phuoc, MD, FACS, at the UNM Comprehensive Cancer Center is pioneering new surgeries in New Mexico using the da Vinci robot. Robotic surgeries, he says, offer several advantages and combine the best features of open and laparoscopic surgeries t...

Expert Available

– University of New Mexico Comprehensive Cancer Center


Ludwig Researchers Present Advances in CAR T Cell Therapeutics, Precision Medicine and Cancer Diagnostics at AACR Annual Meeting 2019

Ludwig Cancer Research released today the full breadth of findings to be presented by Ludwig researchers at this year’s American Association for Cancer Research (AACR) Annual Meeting in Atlanta, Ga., March 29 – April 3, 2019. Research conducted b...

– Ludwig Cancer Research

AACR Annual Meeting 2019, March 29-April 3


New Clinical Offering Aims to Provide Relief for Women with Breast Cancer who have Painful Sex

Vaginal laser is a non-hormonal treatment, which is reported to alleviate symptoms of dryness and pain in 95 percent of the women who undergo the laser treatment. However, because insurance does not cover the laser treatments, it is cost prohibitive ...

– Northwestern Medicine


Cancer Announcements


Johns Hopkins Researchers Receive Swim Across America Grants to Fight Colon Cancer, Study Immune System Role in Lung Cancer

Two Johns Hopkins Kimmel Cancer Center researchers received grants from Swim Across America to fund work for more effective ways to fight colorectal cancer and find out what role the immune system plays in non-small cell lung cancer.

– Johns Hopkins Medicine


Seattle Cancer Care Alliance Expands Access to Nationally Recognized Treatment

Seattle Cancer Care Alliance is opening two new patient care centers in Issaquah, WA and in Poulsbo, WA.

– Seattle Cancer Care Alliance


UCSF Oncologist Answers Pancreas Cancer FAQs on Facebook Live

Following the self-disclosure of Jeopardy's Alex Trebek that he is battling pancreas cancer, ABC7 News sat down with UCSF's Dr. Andrew Ko at our Mission Bay campus to discuss common questions about the disease.

– UCSF Helen Diller Family Comprehensive Cancer Center


NIH Awards $11.4 Million to Establish Kansas Institute for Precision Medicine at KU Medical Center

A team led by Andrew Godwin, PhD, deputy director of The University of Kansas Cancer Center and director of molecular oncology in the department of Pathology and Laboratory Medicine, has been awarded a five-year, $11.4 million National Institutes of ...

– University of Kansas Cancer Center


NCCN Announces Six Quality Improvement Projects in Gastric Cancer Care Approved for Collaboration with Lilly Oncology

The National Comprehensive Cancer Network® (NCCN®) Oncology Research Program (ORP) and Eli Lilly and Company (NYSE: LLY) today announced six projects that aim to improve the delivery of gastric and gastroesophageal junction (GEJ) cancer care in the...

– National Comprehensive Cancer Network® (NCCN®)


Susan Cohn Receives AACR-Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research

The American Association for Cancer Research honors Susan Cohn, MD, for her leadership in clinical trials to improve treatment and survival for neuroblastoma.

– University of Chicago Medical Center

AACR Annual Meeting, March 29 - April 3

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