|Cancer Research Wire|
Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.
In a study published today in the journal PLOS Biology, researchers at Penn Medicine identify the mechanisms behind tumor growth following circadian disturbances and show cancer treatment may be more effective at specific times of day.
– Perelman School of Medicine at the University of Pennsylvania
PLOS Biology / April 2019
embargoed until 30-Apr-2019, 14:00 ET
A new report by researchers at La Jolla Institute found that a genetic deletion, or mutation, of TET2 and TET3 in mouse B cells damps down the generation of functional IgG antibodies, decreasing the effectiveness of immune responses.
– La Jolla Institute for Immunology
Science Immunology; CA210043; AI109842; AI128589 ; AI127642; MH111267; GM128938; S10OD016262; S10RR027366 Embargo expired on 26-Apr-2019 at 14:00 ET
An open-label, multi-cohort Phase II trial, led by investigators at The University of Texas MD Anderson Cancer Center, reports that treatment with the drug tagraxofusp resulted in high response rates in patients with blastic plasmacytoid dendritic ce...
– University of Texas M. D. Anderson Cancer Center
New England Journal of Medicine Embargo expired on 24-Apr-2019 at 17:00 ET
Restrictive prior authorization practices cause unnecessary delays and interference in care decisions for cancer patients, according to a new survey of nearly 700 radiation oncologists — physicians who treat cancer patients using radiation— relea...
– American Society for Radiation Oncology (ASTRO) Embargo expired on 25-Apr-2019 at 09:30 ET
Cancer cells have various tricks up their metaphorical sleeves to survive in the face of chemotherapy, radiotherapy and other cancer treatments. Now researchers at Mayo have decoded one of those tricks using cell lines and patient-derived cancer cell...
– Mayo Clinic
In a new study, Yale Cancer Center scientists have demonstrated a powerful method to analyze how tumor cells are altered as they metastasize to the brain.
– Yale Cancer Center
Scientists have taken one of the most in-depth looks ever at the riot of protein activity that underlies colon cancer and have identified potential new molecular targets to try to stop the disease.
– Pacific Northwest National Laboratory
Cell, April 25, 2019; National Cancer Institute U24CA159988; National Cancer Institute U24CA210954; National Cancer Institute U24CA160019; National Cancer Institute 24CA210955 ...
The vaccine proves safe in a small sample of human subjects, opening the way for the next phase of testing
– Thomas Jefferson University
Journal for ImmunoTherapy of Cancer
Arsenic-based therapy can reverse drug tolerance in acute myeloid leukemia, Cancer Center researchers at BIDMC show.
– Beth Israel Deaconess Medical Center
Cell Research; ALTF 1011-2014; LTFCOFUND2013; GA-20130609409; 5437-16; C.I. 130011240012025124540; R35CA197529; R01CA142874
Using human cancer cells, tumor and blood samples from cancer patients, researchers at Johns Hopkins Medicine have uncovered the role of a neurotransmitter in the spread of aggressive cancers. Neurotransmitters are chemical “messengers” that tran...
– Johns Hopkins Medicine
Cell Reports; R01-CA193895, R01-CA12314, 1S10OD025226-01, UL1 TR 001079
To explain a person’s actions in the present, it sometimes helps to understand their past, including where they come from and how they were raised. This is also true of tumors. Delving into a tumor’s cellular lineage, a Ludwig Cancer Research stu...
– Ludwig Cancer Research
Nature, Apr 2019
The protein BRAF is a key player in the development of many different types of cancer, including melanoma. Scientists have known that BRAF becomes activated by growth factors and subsequently stimulates downstream proteins that promote cancer cell gr...
– Moffitt Cancer Center
Case Western Reserve University researchers and partners, including a collaborator at Cleveland Clinic, are pushing the boundaries of how “smart” diagnostic-imaging machines identify cancers—and uncovering clues outside the tumor to tell whethe...
– Case Western Reserve University
JAMA Network Open, April-2019
Researchers at Dana-Farber Cancer Institute have devised a risk model for determining whether patients with AWM have a low, intermediate, or high risk of developing symptomatic Waldenström macroglobulinemia
– Dana-Farber Cancer Institute
Journal of Clinical Oncology
Study by Huntsman Cancer Institute researchers finds air pollution put childhood cancer survivor at an increased risk for hospitalization
– Huntsman Cancer Institute at the University of Utah
International Journal of Environmental Research and Public Health
A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.
– Beth Israel Deaconess Medical Center
Health Affairs; Nature Metabolism; Nature; Cell Research
A USC Norris study aims to increase clinical trial enrollment among low-income patients and racial and ethnic minorities by offering financial assistance for out-of-pocket costs associated with the trial. Because patients from low-income and racial m...
– University of Southern California (USC) Health Sciences
Mary Jo Gilmer studies the impact animals can have on children with life-threatening conditions. She recently received a grant from nonprofit Human Animal Bond Research Institute (HABRI) for a pilot program investigating the health benefits of human-...
– Vanderbilt University Medical Center
Human Animal Bond Research Institute
Radiation oncologists have come to Capitol Hill today to urge Congress to support policies that safeguard cancer patients’ access to high-quality, value-based health care. The doctors will meet with Congressional leaders during the American Society...
– American Society for Radiation Oncology (ASTRO)
– Mount Sinai Health System
– Wake Forest Baptist Medical Center
Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have been awarded a $4.6 million grant from the California Institute for Regenerative Medicine – also known as CIRM – to support a phase I clinical...
– University of California, Los Angeles (UCLA), Health Sciences
Following a national search, renowned physician-scientist Eric G. Pamer, MD, has been recruited to be the inaugural faculty director of the Duchossois Family Institute at the University of Chicago Medicine starting July 1.
– University of Chicago Medical Center
Alexander Kornienko, a professor in the Department of Chemistry and Biochemistry at Texas State University, has been awarded a National Institutes of Health (NIH) grant to study the potential of a fungus-derived treatment for an aggressive, deadly fo...
– Texas State University
Dr. Mullighan will help guide precision medicine, preclinical and other strategic research initiatives within the cancer center
– St. Jude Children's Research Hospital
National Comprehensive Cancer Network to adapt NCCN Guidelines® for Breast, Cervical, and Rectal Cancer to better meet cancer burden and resource levels in Bolivia.
– National Comprehensive Cancer Network® (NCCN®)
Yale Cancer Center (YCC) and Smilow Cancer Hospital (SCH) are proud to announce a five-year grant awarded by The Frederick A. DeLuca Foundation to establish The DeLuca Center for Innovation in Hematology Research.
– Yale Cancer Center
Rutgers Cancer Institute of New Jersey, the state’s only Comprehensive Cancer Center as recognized by the National Cancer Institute (NCI), has been awarded a $15.1 million grant (P30CA072720) as part of its successful 2019 redesignation.
– Rutgers Cancer Institute of New Jersey