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Newswise Special Wire
Wednesday, May 22, 2019

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Newswise Cancer Research Wire for 22-May-2019

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Cancer Research

New Study Estimates Preventable Cancer Burden Linked to Poor Diet in the U.S.

A new study from researchers at the Friedman School of Nutrition Science and Policy at Tufts estimated the association between suboptimal consumption of seven types of foods and specific cancers. They found that poor diet is on par with alcohol, exce...

– Tufts University

JNCI Cancer Spectrum; R01HL115189; R01MD011501

Embargo expired on 22-May-2019 at 12:00 ET

A Road Map to Stem Cell Development

Johns Hopkins Medicine researchers report they have created a method of mapping how the central nervous system develops by tracking the genes expressed in cells. The technique, demonstrated in mouse retinas for this study, follows the activity of the...

– Johns Hopkins Medicine

Neuron; R01EY020560, U01EY027267, F32EY024201, K99EY027844, K08EY027093, R01XA177669, U01CA212007, 2018-183445, 2018-183444 ; C026429, C03133, C30290GG, ; 2018-183445, 2018-183444...

Embargo expired on 22-May-2019 at 11:00 ET

New Technique Promises Improved Metastatic Prostate Cancer Detection

Results reported in Biomicrofluidics promise a new way to detect prostate cancer through a simple device, which forces cell samples through channels less than 10 microns wide. When prostate cancer cells are forced through, the metastatic cells exhibi...

– American Institute of Physics (AIP)


Embargo expired on 21-May-2019 at 11:00 ET

New method simplifies the search for protein receptor complexes, speeding drug development

A new method of assessing the actions of medicines by matching them to their unique protein receptors has the potential to greatly accelerate drug development and diminish the number of drug trials that fail during clinical trials.

– University of Wisconsin-Milwaukee

Nature Methods

Embargo expired on 20-May-2019 at 11:00 ET

Big Data Reveals Hidden Subtypes of Sepsis

Much like cancer, sepsis isn’t simply one condition, but rather many conditions with varying clinical characteristics that could benefit from different treatments, according to a study involving more than 100,000 patients. The findings could explai...

– Health Sciences at the University of Pittsburgh

JAMA; American Thoracic Society; R35GM119519, P50GM076659, R34GM102696, R01GM101197, GM107231, R01LM012095, K08GM117310-01A1, GM61992.

Embargo expired on 19-May-2019 at 15:00 ET

Blood Test Can Measure Effectiveness of Treatments for Aggressive Skin Cancers

Blood tests that track the amount of tumor DNA can ― after only one month of drug therapy ― detect how well treatment is working in patients with skin cancer, a new study finds.

– NYU Langone Health

ASCO Annual Meeting

Embargo expired on 15-May-2019 at 17:00 ET

Proton Therapy for Cancer Lowers Risk of Side Effects

Proton therapy results in fewer side effects than traditional X-ray radiation therapy for many cancer patients, according to a new study led by Washington University School of Medicine in St. Louis and the Perelman School of Medicine at University of...

– Washington University in St. Louis

ASCO annual meeting 2019

Proton Therapy Lowers Risk of Side-Effects Compared to Conventional Radiation

Cancer patients getting proton therapy instead of traditional photon radiation are at a significantly lower risk of experiencing side-effects from their radiation therapy, while cure rates are almost identical between the two groups.

– Perelman School of Medicine at the University of Pennsylvania

ASCO 2019

Potential Glioblastoma Drug Reactivates p53 Tumor Suppressor to Treat Deadly Brain Cancer

New drug also may increase effectiveness of oral chemotherapy for these tumors, known for their resistance to treatment.

– Newswise

Int J Oncol

Key Acid-Activated Protein Channel Identified

Johns Hopkins researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart attack, cancer and inflammat...

– Johns Hopkins Medicine


Brain Cancer Drug Reactivates Body's Natural Defenses

Drug reactivates p53 tumor suppressor protein and increases chemotherapy effectiveness in potential glioblastoma breakthrough.

– Sbarro Health Research Organization (SHRO)

Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide. Int J Oncol.

Key Drug Target Shown Assembling in Real-Time

Over one-third of all FDA-approved drugs act on a specific family of proteins: G-protein coupled receptors (GPCRs). Drugs to treat high blood pressure, asthma, cancer, diabetes and myriad other conditions target GPCRs throughout the body—but a rece...

– Case Western Reserve University


Zebrafish Help Researchers Explore Alternatives to Bone Marrow Donation

UC San Diego researchers discover new role for epidermal growth factor receptor in blood stem cell development, a crucial key to being able to generate them in the laboratory, and circumvent the need for bone marrow donation.

– University of California San Diego Health

Nature Cell Biology

Improving Isotope Supply for a Cancer-Fighting Drug

Production of actinium-227 ramps up for use in a drug to fight prostate cancer that has spread to bone.

– Department of Energy, Office of Science

Applied Radiation and Isotopes 114, 19 (2016). [DOI: 10.1016/j.apradiso.2016.05.002]

Cutting the time on early disease diagnoses with extracellular vesicles

A research team led by the University of Notre Dame is working to cut the test time for disease biomarkers.

– University of Notre Dame

Nature Communications Biology

Dangerous pathogens use this sophisticated machinery to infect hosts

Gastric cancer, Q fever, Legionnaires' disease, whooping cough--though the infectious bacteria that cause these dangerous diseases are each different, they all utilize the same molecular machinery to infect human cells.

– California Institute of Technology

Nature Microbiology

Prostate Cancer Research Examines Radiation Protocol for the Whole Pelvis

In a new study published by European Urology, UCLA researchers and colleagues from ten other institutions examined the protocol for treating aggressive prostate cancer. With aggressive forms of this disease, it is often unclear if radiation therapy s...

– University of California, Los Angeles (UCLA), Health Sciences

European Urology

Rapid ID of tumor cell metabolism aids treatment

NIBIB-funded researchers used photoacoustic imaging for rapid measurement of metabolic rate of individual cells from breast tumors—information that can help guide treatment strategies.

– National Institute of Biomedical Imaging and Bioengineering

Nat Biomed Eng, Apr-2019; EB016986; CA186567

Scientists develop technology to capture tumor cells

Instead of searching for a needle in a haystack, what if you were able to sweep the entire haystack to one side, leaving only the needle behind? That’s the strategy researchers in the University of Georgia College of Engineering followed in develop...

– University of Georgia

Johns Hopkins Researchers Find Widely “Inconsistent” Use of Antibodies in Lab Experiments

Scientists at the Johns Hopkins Kimmel Center say they have affirmed widespread inconsistencies in the use of a common laboratory procedure called immunohistochemical staining, and say the variations are making many laboratory experiments unreliable....

– Johns Hopkins Medicine

Asian Journal of Urology; P30 CA006973, P50 CA058236, U01 CA196390, W81XWH-18-2-0013, W81XWH-18-2-0015

Potential Targeted Treatment for Acute Myeloid Leukemia Identified

Scientists from Sanford Burnham Prebys have shown that a protein called BMI1 is a promising drug target for an AML subtype in which two normally separate genes, CALM and AF10, fuse together. The findings, published in Experimental Hematology, provide...

– Sanford Burnham Prebys Medical Discovery Institute

Experimental Hematology; R00CA154880; P30CA030199

Researchers Pinpoint Why Lymphoma Patients May Become Resistant to Specific Therapy, Identify Strategy to Overcome It

With more targeted therapies being approved each year for cancer, the development of drug resistance to these agents is a growing concern. It has often been assumed that drug resistance is due to the presence or development of additional genetic alte...

– Moffitt Cancer Center

Cancer Cell, May 2019

Enhanced Anticancer Compound May Allow for Precise Activation and Tracking of Treatment

Wistar and the University of South Florida researchers have advanced a novel compound that specifically targets the endoplasmic reticulum (ER) stress response that is frequently hyperactivated in cancer and promotes survival of cancer cells during st...

– Wistar Institute

Journal of Medicinal Chemistry



– Mayo Clinic

Pesquisa que decifra câncer unilateral que sobrevive ao tratamento, propõe uma forma de preveni-lo

As células do câncer têm, metaforicamente falando, inúmeros truques na manga para sobreviver frente à quimioterapia, radioterapia e outros tratamentos contra o câncer. Agora, os pesquisadores na Mayo Clinic decifraram um desse truques usando li...

– Mayo Clinic

Cancer Experts and Features

Mayo experts to present findings at Digestive Disease Week 2019

Mayo Clinic researchers are among international experts who will present findings next week at Digestive Disease Week 2019, the world's largest gathering of physicians, researchers and industry leaders in gastroenterology and related fields.

– Mayo Clinic

Digestive Disease Week 2019, May 18-21, 2019

Embargo expired on 21-May-2019 at 18:00 ET

Clinicians could prescribe fitness apps to help cancer survivor's exercise

Fitness apps could be prescribed by clinicians to help patients recovering from cancer increase their physical activity levels

– University of Surrey

Journal of Cancer Survivorshipreports

Dana-Farber researchers present findings in more than 70 research studies at ASCO annual meeting 2019

Dana-Farber Cancer Institute researchers are presenting more than 70 research studies at the 2019 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, May 31st- June 4th. ASCO is the world’s largest clinical cancer researc...

– Dana-Farber Cancer Institute

ASCO Annual Meeting May 31-June 4 2019

Expertos de Mayo presentan sus resultados durante la Semana de las Enfermedades Digestivas 2019

Los investigadores de Mayo Clinic estuvieron entre los expertos internacionales que presentaron sus resultados durante la Semana de las Enfermedades Digestivas 2019, que es la mayor reunión mundial de médicos, investigadores y líderes en la indust...

– Mayo Clinic

Improved Imaging for Prostate Cancer Could Lead to More Effective Treatment

Engineers at Rensselaer Polytechnic Institute are working to improve imaging methods in order to make medicine more precise and personalized. This work will be a critical component of a new interdisciplinary research project funded with $1.4 million ...

– Rensselaer Polytechnic Institute (RPI)

Cancer Research Highlights from Upcoming ACSM 66th Annual Meeting in Orlando

Last year, an estimated 18 million cancer cases existed worldwide. This year, an estimated 1.76 new cancer cases will be diagnosed and 606,000 cancer deaths will occur in the United States. The number of cancer survivors worldwide is also growing, wi...

– American College of Sports Medicine (ACSM)

ACSM 66th Annual Meeting

Texas raises tobacco sales age to 21 to limit youth exposure and protect health

The University of Texas MD Anderson Cancer Center applauds the Texas Legislature today for passing Senate Bill 21, which raises the minimum legal sale age for all tobacco products from 18 to 21.

– University of Texas M. D. Anderson Cancer Center

Cancer Research Institute Champions Cancer Immunotherapy Month™ in June

The Cancer Research Institute announced today a series of public education and awareness offerings during its seventh annual Cancer Immunotherapy Month™ in June.

– Cancer Research Institute

Marine Organisms Hold Promise for Treating Triple Negative Breast Cancer

More than 50 percent of cancer drugs currently used have originated from natural products. Researchers have received $801,000 from the Florida Department of Health for a project to investigate the use of marine natural compounds as potential treatmen...

– Florida Atlantic University

Nationally recognized #WCHN oncologists will be at #ASCOAnnualMeeting & available for comment about breast, GI, GU & gynecologic cancers; targeted therapy; immunotherapy. Contact @ForniAmy

– Western Connecticut Health Network

Cancer Announcements

Stephen Piscotty of the Oakland Athletics wins 54th Annual Hutch Award

Right fielder honored for overcoming personal tragedy, demonstrating a commitment to scientific research and exemplifying the spirit of Fred Hutchinson

– Fred Hutchinson Cancer Research Center

Women’s Heart Fund Hosts Annual Reception in Support of the Center for Survivorship and Wellness Care at Jersey Shore University Medical Center’s HOPE Tower

The Women’s Heart Fund is hosting its annual reception in support of the Center for Survivorship and Wellness Care at Hackensack Meridian Health Jersey Shore University Medical Center’s HOPE Tower on Friday, May 31, 2019 at Bay Head Yacht Club in...

– Hackensack Meridian Health

David Jaffray, Ph.D., Named Chief Technology and Digital Officer

The University of Texas MD Anderson Cancer Center today named David Jaffray, Ph.D., as its first-ever chief technology and digital officer. Jaffray will begin his new duties overseeing MD Anderson’s Information Services division and Information Sec...

– University of Texas M. D. Anderson Cancer Center

Rush's Dr. Shikha Jain Named ResearcHERS Program Ambassador

Rush University Cancer Center oncologist Shikha Jain, MD, has been named an ambassador for the American Cancer Society's ResearcHERS program — a unique effort to fund women with innovative research ideas and dedication to discovering lifesaving can...

– Rush University Medical Center

Boston Doctors Honored for Pediatric Cancer Teamwork

The American Academy of Dermatology has honored oncologist Jennifer Whangbo, MD, PhD, and dermatologist Jennifer Huang, MD, FAAD, as Patient Care Heroes for their collaboration in caring for pediatric stem cell transplant patients.

– American Academy of Dermatology

ACR Foundation Presents Global Humanitarian Awards

The American College of Radiology Foundation (ACRF) presented its Global Humanitarian Award to Richard N. Hirsh, MD, FACR, of Akron, OH (individual) and Mamotest of Argentina (group). The awards, honoring the individual’s and group’s positive glo...

– American College of Radiology (ACR)

Case Comprehensive Cancer Center Awarded Nearly $9 Million to Expand Access to Clinical Trials

Case Comprehensive Cancer Center has been selected, once again, as a Lead Academic Participating Site by the National Cancer Institute. The renewal comes with a six-year, $8.9 million grant that will enable the center to provide patients with additio...

– Case Western Reserve University


UK Becomes First Center in the Country to Open Total Cancer Care Protocol to Pediatric Patients

UK HealthCare recently opened the Oncology Research Information Exchange Network’s (ORIEN) Total Cancer Care Protocol to pediatric patients, becoming the first cancer program in the country to do so.

– University of Kentucky

New Project Funded by NCI, NIDA, Aims to Eradicate Hepatitis C in Eastern Ky. County

With $15 million from the National Cancer Institute and National Institute on Drug Abuse and a donation of 900 doses of a 12-week treatment from Gilead Sciences Inc., University of Kentucky's Jennifer Havens has the goal of eradicating HCV in Perry C...

– University of Kentucky





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