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Newswise Special Wire
Tuesday, May 28, 2019

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Newswise Cancer Research Wire for 28-May-2019
 

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.


Cancer Research


De-TOXing exhausted T cells may bolster CAR T immunotherapy against solid tumors

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

– La Jolla Institute for Immunology

Proceedings of the National Academy of Sciences (PNAS); AI109842; AI040127; AI108651; AI140095; GM007752; S10OD016262; S10 RR027366

Embargo expired on 27-May-2019 at 15:00 ET


Adding Bevacizumab to Lung Cancer Treatment Results in Modest Overall Survival Benefits, According to Study in JNCCN from Abramson Cancer Center

Researchers from University of Pennsylvania find adding bevacizumab to carboplatin-pemetrexed was effective in treating non-squamous non-small cell lung cancer, in new study published in JNCCN—Journal of the National Comprehensive Cancer Network.

– National Comprehensive Cancer Network® (NCCN®)

JNCCN—Journal of the National Comprehensive Cancer Network

Embargo expired on 23-May-2019 at 09:15 ET


Researchers Advance Search For Laboratory Test to Predict Spread of Breast Cancer

Researchers at The Johns Hopkins University and other institutions report that a new laboratory test that induces cancer cells to squeeze through narrow spaces has the potential to accurately predict which breast cancers and other solid tumors are li...

– Johns Hopkins Medicine

Nature Biomedical Engineering; R01-CA183804, R01-CA216855, R01-CA154624, R01-CA174385, K01-CA166576, RP180466, 509800, CA16059, W81XWH-17-1-0246, RSG-18-028-01


New Evidence Supports Surgery For Rare Type of Brain Lymphoma

Through a systematic review of published studies going back 50 years, Johns Hopkins Medicine researchers say they have identified a distinct subtype of primary central nervous system (PCNS) lymphoma that should be considered for surgical removal, sug...

– Johns Hopkins Medicine

World Neurosurgery


Finding A Cell’s True Identity

Scientists have long sorted cells into different varieties based on their appearance under a microscope or, for differences that are more visually subtle, based on the behavior of a handful of genes. But in a bid to reveal even more distinctive diffe...

– Johns Hopkins Medicine

Cell Systems; R01EY020560 and U01EY027267, F32EY024201 K99EY027844, R01CA177669, U01CA196390, U01CA212007, P30CA006973, IOS-1656592; 2018-182718, 2018-183445, and 2018-183444


More than a protein factory

Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle’s role in destroying healthy mRNAs, the messages that decode DNA into protein.

– Stowers Institute for Medical Research

eLife


Technology better than tape measure for identifying lymphedema risk

New research by School of Nursing professor Sheila Ridner finds that a special scan measuring lymphatic fluid volume is significantly better than a tape measure at predicting which women undergoing treatment for breast cancer are at risk of developin...

– Vanderbilt University

Annals of Surgical Oncology


Learning From a Rare Disease

Dr. Hua-Ying Fan studies the cells of people who don’t get cancer. These people have a rare inherited disorder called Cockayne syndrome and, unfortunately, they don’t live long enough to develop cancer. But by studying their cells, Fan may be abl...

– University of New Mexico Comprehensive Cancer Center

Journal of Biological Chemistry


E-cigarette use climbing among cancer patients and cancer survivors

A new study by a UT Southwestern oncologist exposes what she calls an alarming trend. E-cigarette use is climbing among cancer patients and cancer survivors and could have consequences in the future.

– UT Southwestern Medical Center

JAMA Oncology


Novel Role in Spatial Chromosome Organization Identified for Frequently Mutated Cancer Protein

New research from The Wistar Institute sheds light on the function of the ARID1A protein, encoded by a gene that is among the most frequently mutated across human cancers.

– Wistar Institute

Science Advances


Summit Charts a Course to Uncover the Origins of Genetic Diseases

A team led by Ivaylo Ivanov of Georgia State University used the 200-petaflop IBM AC922 Summit system, the world’s smartest and most powerful supercomputer, to develop an integrative model of the transcription preinitiation complex (PIC), a complex...

– Oak Ridge National Laboratory

Nature Structural & Molecular Biology, May-2019


Cancer Experts and Features


Clinical Program / Research Highlights from Upcoming 2019 ACSM Annual Meeting

If you're looking for new story ideas, here is a selection of the more than 100 talks on clinically based topics that will be presented at ACSM's 66th Annual Meeting beginning May 28 in Orlando, Florida.

– American College of Sports Medicine (ACSM)


Ahead of Memorial Day, the American Academy of Dermatology Reminds Americans to Use Protection

An estimated 9,500 people in the United States are diagnosed with skin cancer every day, yet many Americans will put themselves at greater risk for skin cancer over the upcoming holiday weekend. New data from the American Academy of Dermatology revea...

– American Academy of Dermatology


Northwestern Medicine oncologists and researchers present findings at 2019 ASCO Annual Meeting

– Northwestern Medicine


University of Michigan Expert Explores Racial Disparity in Prostate Cancer Mortality

– Michigan Medicine - University of Michigan


Cancer Announcements


Polly’s Run in 10th Year of Fight Against Pancreatic Cancer

The 10th Anniversary of Polly’s Run, the largest fundraiser for pancreatic cancer in New Mexico, will take place Sunday, June 2, at Tiguex Park near Albuquerque’s Old Town. All proceeds benefit the Polly Rogers Pancreatic Cancer Research Fund at ...

– University of New Mexico Comprehensive Cancer Center

Embargo expired on 28-May-2019 at 07:05 ET


Renowned Urologic Oncologist Selected to Lead Urology Bladder Cancer Program at NYU Langone Health

Gary D. Steinberg, MD , a nationally recognized specialist in the surgical management of bladder cancer, has been named director of the Goldstein Urology Bladder Cancer Program at NYU Langone Health. His recruitment enhances the team of clinicians a...

– NYU Langone Health


UVA Partnering to Improve HPV Vaccination Rates in Western Virginia

University of Virginia Health System is joining a coalition of healthcare organizations to improve vaccination rates in western Virginia for human papillomavirus (HPV), a leading cause of cancer.

– University of Virginia Health System

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