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Newswise Special Wire
Tuesday, July 23, 2019

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Newswise Cancer Research Wire for 23-Jul-2019

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Cancer Research

Cancer Lab on Chip to Enable Widespread Screening, Personalized Treatment

Pathology labs mounted on chips are set to revolutionize the detection and treatment of cancer by using devices as thin as a human hair to analyze bodily fluids. The technology, known as microfluidics, promises portable, cheap devices that could enab...

– American Institute of Physics (AIP)


Embargo expired on 23-Jul-2019 at 11:00 ET

Molecular Sensor Scouts DNA Damage and Supervises Repair

Using single-molecule imaging, researchers witness how molecules find and fix damaged DNA

– Health Sciences at the University of Pittsburgh

Nature Structural and Molecular Biology; R01ES019566, R01ES028686, R33ES025606, P30CA047904, R01CA067985, 1ZIAES050158, 1ZIAES050159, T32GM088119

Embargo expired on 22-Jul-2019 at 11:00 ET

New technique helps create more personalized therapies for people with hard-to-treat cancers

Using an ultra-sensitive and high-throughput isolation technology, UCLA researchers were able to characterize and identify the neoantigens driving the antitumor responses in a patient treated with anti-PD-1 blockade and isolate the T cell receptors r...

– University of California, Los Angeles (UCLA), Health Sciences

American Associate of Cancer Research special conference

Embargo expired on 22-Jul-2019 at 08:00 ET

Scientists develop promising drug for treating ovarian and pancreatic cancers

Known as two of the most lethal cancers, ovarian and pancreatic cancer are often called silent killers. As a result, they frequently go undetected until they’re too late to effectively treat. Cancer scientists at Houston Methodist have been vigilan...

– Houston Methodist

Clinical Cancer Research, July 2019

Embargo expired on 22-Jul-2019 at 10:00 ET

Discovery shows how difficult-to-treat prostate cancer evades immune system

Discovery shows how difficult-to-treat prostate cancer evades immune system and reports pre-clinical development of novel treatment and potential for combination use with immunotherapy drugs.

– University of Texas M. D. Anderson Cancer Center

Cancer Cell

Embargo expired on 18-Jul-2019 at 11:00 ET

New Research Identifies Gene That Hides Cancer Cells from Immunotherapy

A team at Fred Hutchinson Cancer Research Center has identified a gene that could make immunotherapy treatments, specifically checkpoint inhibitors, work for a wider variety of cancer patients.

– Fred Hutchinson Cancer Research Center

Developmental Cell

Embargo expired on 18-Jul-2019 at 11:00 ET

Who’s minding the children? Women report skipping scientific conferences because of child care

Many women find themselves skipping scientific conferences because of family obligations, a new study finds. Women were less likely than men to attend scientific meetings, although both genders noted that conferences were important to career advancem...

– Michigan Medicine - University of Michigan

JAMA Oncology

Embargo expired on 18-Jul-2019 at 11:00 ET

Common Feature of Cancer Cells That Makes Them Appear Overstuffed May Also Be Their Achilles’ Heel

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry genetic material. The vul...

– Johns Hopkins Medicine

Nature; R35-GM118172, R01-HG006677, R01-GM114675, U54-CA210173, 16YOUN21

Encephalitis Identified as Rare Toxicity of Immunotherapy Treatment

The results, published July 22 in Nature Medicine, are the latest findings by VICC researchers chronicling rare but serious toxicities that may occur with immune checkpoint inhibitors, the most widely prescribed class of immunotherapies. The research...

– Vanderbilt University Medical Center

Nature Medicine

New, High-Resolution Images Reveal Clues to Improve Anti-Nausea Drugs for Cancer Patients

A new study using a special type of electron microscope using samples cooled to extremely cold temperatures provides critical information for drug developers seeking to reduce nausea and vomiting side effects of cancer treatments.

– Case Western Reserve University

Nature Communications

Researchers Find Simple Way to Predict and Prevent Dangerous Blood Clots in Patients Treated for Multiple Myeloma

New research in JNCCN from the Hutchinson Institute for Cancer Outcomes Research (HICOR) within the Fred Hutch/University of Washington Cancer Consortium—part of the Seattle Cancer Care Alliance—identifies a simple way to help cancer doctors cari...

– National Comprehensive Cancer Network® (NCCN®)

JNCCN—Journal of the National Comprehensive Cancer Network

Cracking a Code: Landmark Prospective Study Helps Researchers Better Understand Which MGUS Patients Will Progress to a Multiple Myeloma Diagnosis

Memorial Sloan Kettering Cancer Center (MSK) researchers published new results that found that individuals with low-risk or intermediate-risk myeloma precursor disease known as monoclonal gammopathy of undetermined significance (MGUS) can convert to ...

– Memorial Sloan Kettering Cancer Center

JAMA Oncology

Study Finds Key Metabolic Changes in Patients with Chemotherapy-Associated Cardiotoxicity

Researchers at Beth Israel Deaconess Medical Center (BIDMC) embarked on a study to investigate whether early changes in energy-related metabolites in the blood – measured shortly after chemotherapy – could be used to identify patients who develop...

– Beth Israel Deaconess Medical Center

Journal of Cardiovascular Translational Research

Crunching the Numbers of Cancer Metastasis

In a study published in Scientific Reports, first author Yamicia D. Connor, MD, PhD, a resident in the Department of Obstetrics and Gynecology at Beth Israel Deaconess Medical Center (BIDMC), and colleagues, reveal that unlike non-metastatic cells, b...

– Beth Israel Deaconess Medical Center

Scientific Reports; W81XWH-07-1-0482; W81XWH-09-1-0700; BC132168; UL1 TR001102; 1R01CA135242-01A2; CA229772; CA214411; CA236702; T32GM007753...

Cancer Device Created at Rutgers to See if Targeted Chemotherapy is Working

Rutgers researchers have created a device that can determine whether targeted chemotherapy drugs are working on individual cancer patients. The portable device, which uses artificial intelligence and biosensors, is up to 95.9 percent accurate in coun...

– Rutgers University-New Brunswick

Microsystems & Nanoengineering; Rutgers Today

Researchers wirelessly hack ‘boss’ gene, a step toward reprogramming the human genome

A new University at Buffalo-led study describes how researchers wirelessly controlled FGFR1 — a gene that plays a key role in how humans grow from embryos to adults — in lab-grown brain tissue. The ability to manipulate the gene, the study’s...

– University at Buffalo

Proceedings of IEEE

Cancer Announcements

Coriell Institute for Medical Research Now a Collaborator in Prestigious Stand Up To Cancer Grant

The Coriell Institute for Medical Research is now participating in a prestigious SU2C Catalyst® grant from Stand Up To Cancer for the study of epigenetic therapy in treating urothelial cancer, a common form of cancer typically found in the bladder. ...

– Coriell Institute for Medical Research

$2M in Grants Drives Scientific Exploration of Rare Blood Cancer

More than $2 million in grants recently awarded to a Rutgers Cancer Institute of New Jersey resident researcher will support examination of potential treatment targets for T-cell acute lymphoblastic leukemia (T-ALL).

– Rutgers Cancer Institute of New Jersey

Lifetime Achievement award tops decades of work with patients and cancer groups

Dr. Phil Evans was honored with National Breast Cancer Foundation's Lifetime Achievement Award.

– UT Southwestern Medical Center





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