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Newswise Special Wire
Tuesday, September 24, 2019

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Newswise Cancer Research Wire for 24-Sep-2019

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Cancer Research

GW Cancer Center Researchers Find Potential Therapeutic Target for Prostate Cancers with PTEN Mutation

PTEN, a tumor suppressor gene mutated in about 20% of prostate cancers, relies on another gene, ARID4B, to function. These findings were published by George Washington University Cancer Center researchers in Nature Communications.

– George Washington University

Nature Communications

Embargo expired on 24-Sep-2019 at 05:00 ET

Strip Steak: Bacterial Enzyme Removes Inflammation-Causing Meat Carbohydrates

When we eat red meat, the animal carbohydrate Neu5Gc is incorporated in our tissues, where it generates inflammation. UC San Diego researchers discovered how gut bacteria enzymes strip our cells of Neu5Gc, introducing the possibility of using the enz...

– University of California San Diego Health

Nature Microbiology

Embargo expired on 23-Sep-2019 at 11:00 ET

Study Identifies Cardiovascular Toxicities Associated with Ibrutinib

After a recent study showed that chronic lymphocytic leukemia patients who received ibrutinib as a frontline treatment had a 7% death rate, a new study offers a clearer picture on the reasons for the deaths.

– Vanderbilt University Medical Center

The Journal of the American College of Cardiology

Embargo expired on 23-Sep-2019 at 14:00 ET

Key similarities discovered between human and archaea chromosomes

A study led by Indiana University is the first to reveal key similarities between chromosomes in humans and archaea. The work could advance use of the single-celled organism in research on cancer.

– Indiana University

Cell; R01GM125579

Embargo expired on 19-Sep-2019 at 11:00 ET

Study finds new way to make chemotherapy more effective against pancreatic cancer

Pancreatic adenocarcinoma (PDAC) is a lethal malignancy that most often is resistant to chemotherapy. Researchers have been searching for ways to increase the sensitivity of the tumors to cancer-fighting drugs. A Mayo Clinic-led study published today...

– Mayo Clinic

Clinical Cancer Research

Embargo expired on 18-Sep-2019 at 11:00 ET

Simple lifestyle modifications key to preventing large percentage of breast cancer cases

Expert reports estimate that one in three breast cancer cases could be prevented by lifestyle modifications.

– North American Menopause Society (NAMS)

30th Annual Meeting of The North American Menopause Society (NAMS)

Can Discrete Choice Experiment Technique Predict Real-World Healthcare Decisions?

Value in Health, the official journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of research demonstrating that discrete choice experiments are able to predict real-world healthcare...

– ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health, Sep-2019

“Metabolic Inhibitor” Compound Extends Survival in Mice with MYC-Expressing Pediatric Brain Tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-c...

– Johns Hopkins Medicine

Translational Oncology; CA171021, SKCCC P30CA006973, 1R01NS103927-01A1, 1R01NS103927, R01CA229451, P30CA006973

New study identifies risk factors for head and neck cancer among 9/11 responders

A recent Rutgers study identified factors that may put people who responded to the 9/11 terrorist attacks at the World Trade Center (WTC) at increased risk for cancers of the head and neck, such as oral cavity, oropharyngeal, and laryngeal cancers.

– Rutgers School of Public Health

Occupational & Environmental Medicine

Onions and garlic are staples of a Puerto Rican condiment. Are they also a recipe for reduced breast cancer risk?

Women who ate the popular Puerto Rican condiment sofrito, which contains onions and garlic, more than once per day had a 67% decreased risk of breast cancer. It's the first population-based study examining the association between onion and garlic con...

– University at Buffalo

Nutrition and Cancer, Aug-2019

Study Suggests New Metabolic Target for Liver Cancer

Disrupting a metabolic pathway in the liver in a way that creates a more “cancer-like” metabolism actually reduces tumor formation in a mouse model of liver cancer. This surprising finding from a Univ. of Iowa study identifies the mitochondrial p...

– University of Iowa

Cell Reports, Sept. 3, 2109; R01DK104998; R01CA132962; R01CA182804; P30CA086862

Engineered killer T cells could provide long-lasting immunity against cancer

In experiments with mice, UCLA researchers have shown they can harness the power of iNKT cells to attack tumor cells and treat cancer. The new method, described in the journal Cell Stem Cell, suppressed the growth of multiple types of human tumors th...

– University of California, Los Angeles (UCLA), Health Sciences

Cell Stem Cell

Leukemia Drug Shows Promise for Treating a Childhood Brain Cancer

Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego researchers describe new use of leukemia drug, nilotinib, to treat subtype of medulloblastoma, a deadly pediatric brain cancer.

– University of California San Diego Health


Identification of a Novel Regulator of Mitochondrial Cell Death Reveals a Promising Target for Cancer Therapy

Wistar researchers have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target.

– Wistar Institute


Hippocampal avoidance using IMRT now recommended as standard of care for brain metastases

Patients with brain metastases who received whole-brain radiotherapy that avoided memory-specific hippocampal neural stem cells experienced preserved cognitive function and reported fewer neurologic symptoms and better cognition over time.

– Northwestern Medicine

American Society for Radiation Oncology Annual Meeting

Here's proof that bowel cancer screening reduces deaths

New research led by the University of South Australia shows just how effective bowel cancer screening is in helping to reduce the number of bowel cancer deaths by up to 45 per cent.

– University of South Australia

BMC Cancer

Johns Hopkins Researchers ID Compound That Could Play A Novel Role In Halting Pancreatic Cancer Progression

In early test tube and mouse studies, investigators at Johns Hopkins Medicine and the Johns Hopkins Kimmel Cancer Center have found that nonmuscle myosin IIC (MYH14), a protein activated in response to mechanical stress, helps promote metastatic beha...

– Johns Hopkins Medicine

Cancer Research; GM66817, GM109863

NUS researchers develop new drug that fights cancer with less renal toxicity

NUS researchers have developed a new anti-cancer drug that have less toxic effects to the kidneys. It works like a ‘magic bullet’ that is delivered directly to the mitochondria. Such targeted approach reduces the drug’s interactions with other ...

– National University of Singapore

Angewandte Chemie International Edition, 03 April 2019

Integrated Imaging Technology Aims To Provide Real-Time Look at Cancer Treatment

If researchers could observe drug delivery and its effect on cancer cells in real time, they would be able to tailor treatment options with unprecedented specificity. An academic-industrial partnership between engineers at Rensselaer Polytechnic ...

– Rensselaer Polytechnic Institute (RPI)

Investigadores de Mayo demuestran reducción de carga de células senescentes en los humanos con fármacos senolíticos

En un pequeño ensayo clínico sobre seguridad y factibilidad, los investigadores de Mayo Clinic por vez primera demostraron que es posible extraer del cuerpo a las células senescentes con los fármacos llamados “senolíticos”. El resultado se v...

– Mayo Clinic


Taking Baby Aspirin Improves Overall Survival for Patients With Head & Neck, Lung Cancer

In companion presentations at the American Society for Therapeutic Radiation Oncology Annual Meeting, doctors from Roswell Park Comprehensive Cancer Center report new evidence that low-dose aspirin and other anti-inflammatories may improve survival i...

– Roswell Park Comprehensive Cancer Center

ASTRO 2019

Pesquisadores da Mayo Clinic apresentarão achados no encontro anual da ASTRO

Médicos da Mayo Clinic apresentarão achados no encontro anual da Sociedade Americana de Radioterapia e Oncologia, de 15 a 18 de setembro, em Chicago.

– Mayo Clinic

تقديم باحثي Mayo Clinic لنتائج الدراسات في الاجتماع السنوي للجمعية الأمريكية لطب الأورام الإشعاعي

سيقدم أطباء Mayo Clinic نتائج الدراسات في الاجتماع السنوي للجمعية الأمريكية لطب الأورام الإشعاعي المنعقد في 15-18 سبتمبر في شيكاغو.

– Mayo Clinic

'Death Star' bacterial structures that inject proteins can be tapped to deliver drugs

By scraping tubeworms off the bottom of boats in the San Diego harbor to study them, San Diego State University

– San Diego State University


Novel anti-cancer nanomedicine for efficient chemotherapy

Researchers at the University of Helsinki in collaboration with researchers from Åbo Akademi University,Finland and Huazhong University of Science and Technology,China have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy.

– University of Helsinki

Nature Communications

Adding Radiation After Immunotherapy Improves Survival Time for Patients with Advanced Lung Cancer

The results of a phase II clinical trial by Yale Cancer Center (YCC) researchers show adding high-dose radiation after immunotherapy stops working increases survival time for patients with metastatic non-small-cell lung cancer (NSCLC).

– Yale Cancer Center

ASTRO 2019

Racial Disparities in Survival Outcomes Shown in Pediatric Hodgkin Lymphoma Patients

In what is believed to be the largest dataset study to date examining the role of race on survival outcome for pediatric patients with Hodgkin lymphoma, investigators at Rutgers Cancer Institute of New Jersey have found that black patients have sign...

– Rutgers Cancer Institute of New Jersey

ASTRO 2019

Exploding shells boost immune response to brain cancer

Researchers at the University of California San Diego figured out a way to combine FDA-approved ultrasound with engineered glass particles to boost the effectiveness of immunotherapy in glioblastomas.

– University of California San Diego

Advanced Therapeutics; 5T32CA153915-08; 5U54CA132379-08; 1RON1NS097649-01; 9R44GM128223-02

Les chercheurs de Mayo Clinic présentent leurs conclusions à la réunion annuelle de l’ASTRO

Les médecins de Mayo Clinic ont présenté leurs conclusions à la réunion annuelle de l’American Society for Therapeutic Radiology and Oncology qui se tiendra du 15 au 18 septembre à Chicago.

– Mayo Clinic

Yale Cancer Center Research Highlighted at ASTRO 2019

Yale Cancer Center (YCC) scientists presented research at the 61st annual American Society for Radiation Oncology (ASTRO) annual meeting in Chicago.

– Yale Cancer Center

ASTRO 2019

New Prostate Cancer Biopsy Reduces Risk of Infection, Improves Accuracy

Loyola Medicine is among the first centers to offer a new minimally invasive prostate cancer biopsy that minimizes the risk of infection and may increase the cancer detection rate. It's called the transperineal prostate biopsy.

– Loyola University Health System

Thousands of Cancer Survivors Gather at MetLife Stadium for 11th Celebrating Life and Liberty Event

Largest-Ever Attendance for Hackensack Meridian Health's Annual Celebration

– Hackensack Meridian Health

Pain Clinic Provides Safe Space for Sickle Cell Patients to Receive Treatment

With the aim of improving pain control and decreasing hospitalizations for vaso-occlusive crisis, the Sickle Cell Team at Children's of Alabama is moving to implement individualized pain plans for patients and pilot an outpatient pain clinic.

– Children's of Alabama

MicroRNA-based Therapy May be New Weapon to Combat Cancer

A technology that manipulates microRNAs (miRNAs) developed by Jingfang Ju, PhD, a biochemist and Professor in the Department of Pathology at the Renaissance School of Medicine at Stony Brook University, and colleagues has shown promise when used as ...

– Stony Brook University

Cancer Experts and Features

Freezing Breast Cancer Cells May Help Avoid Surgery

With Breast Cancer Awareness Month coming up, this timely story highlights a treatment option that kills cancer cells by freezing them -- thereby allowing many early-stage, low-risk breast cancer patients to avoid surgery. Jeanne Anderson is one such...

– Cedars-Sinai

3rd Annual Skin Cancer Awareness Walk Returns to Elk Grove Village September 28

Skin cancer is the most common cancer in the United States, affecting one in five Americans during their lifetime. To help raise awareness of skin cancer prevention and detection, the American Academy of Dermatology will host Skin Cancer, Take a Hike...

– American Academy of Dermatology

MD Anderson and Houston Dynamo unite to kick childhood cancer

MD Anderson and Houston Dynamo unite to kick childhood cancer. MD Anderson faculty and staff, pediatric patients, and their families to raise awareness of childhood cancers at Houston Dynamo vs Orlando City Soccer Club game on Saturday, September 21....

– University of Texas M. D. Anderson Cancer Center

CPRIT awards $11 million to UTHealth for cancer research, prevention

Five innovative cancer-fighting projects at The University of Texas Health Science Center at Houston (UTHealth) received just over $11 million during the latest round of grants awarded by the Cancer Prevention and Research Institute of Texas (CPRIT)....

– University of Texas Health Science Center at Houston

Joseph M. Sanzari Children’s Hospital and John Theurer Cancer Center Launch Clinical Trial Evaluating Gene Therapy for Severe Sickle Cell Disease in Adolescents and Adults

Clinical trial shows potential for some sickle cell patients to be their own stem cell donor.

– Hackensack Meridian Health

Tulane University student spends summer conducting brain tumor research in Switzerland

Tulane University senior James Rogers has been charting a course in the name of research since he arrived on campus in the fall of 2016. Rogers’ journey has led him from New Orleans to Bethesda, Md., across the Atlantic to Scotland and, most recent...

– Tulane University

September Is Pediatric Cancer Awareness Month

The Children’s Cancer Institute at Hackensack University Medical Center celebrates the milestones of patients and the doctors who refuse to give up hope

Expert Available

– Hackensack Meridian Health

Urologic Cancer Expert Brings Latest Science to NYU Langone Hospital–Brooklyn

Mohit Gupta, MD, has been appointed director of urologic oncology and brings the latest surgical techniques in the treatment of prostate and urinary cancers to NYU Langone Hospital–Brooklyn.

Expert Available

– NYU Langone Hospital - Brooklyn

GW Experts Available During Breast Cancer Awareness Month

– George Washington University

What is Ovarian Cancer?

Ovarian Cancer is expected to impact 22,000 U.S. women this year. Rutgers Cancer Institute of New Jersey Gynecologic Oncologist Dr. Mihae Song shares some facts during this Ovarian Cancer Awareness Month.

– Rutgers Cancer Institute of New Jersey

What is Thyroid Cancer?

September is Thyroid Cancer Awareness Month and Dr. Amanda Laird, Chief of Endocrine Surgery at Rutgers Cancer Institute of New Jersey shares information on types of thyroid cancer, how it is diagnosed and treatment options.

– Rutgers Cancer Institute of New Jersey

Cancer Announcements

Ronald Chen Named Chair of Radiation Oncology

Ronald Chen, MD, MPH, has been named the Brandmeyer Chair and Professor of Radiation Oncology at the University of Kansas School of Medicine, clinical service chief at The University of Kansas Health System and associate director for Health Equity at...

– University of Kansas Cancer Center

Embargo expired on 20-Sep-2019 at 12:00 ET

UCSF Launches Benioff Initiative for Prostate Cancer Research

UC San Francisco announced Thursday it will establish the UCSF Benioff Initiative for Prostate Cancer Research, made possible by a $35 million gift from Marc and Lynne Benioff.

– UCSF Helen Diller Family Comprehensive Cancer Center

U-M, Karmanos receive $9.2M grant for prostate cancer research

Michigan's two comprehensive cancer center, the University of Michigan Rogel Cancer and the Barbara Ann Karmanos Cancer Institute, have received a prestigious $9.2 million grant from the National Cancer Institute for prostate cancer research.

– Michigan Medicine - University of Michigan


APHON Announces the 2019 Membership Award Winners at its 43rd Annual Conference

Chicago (Sep. 23, 2019) The Association of Pediatric Hematology/Oncology Nurses (APHON) announced the recipients of the 2019 APHON Membership Awards at its 43rd Annual Conference and Exhibit, held September 5-7 in San Jose, CA. APHON Membership Award...

– Association of Pediatric Hematology/Oncology Nurses (APHON)

Association of Pediatric Hematology/Oncology Nurses Announces Ruth Anne Herring as winner of the 2019 Dr. Patricia Greene Leadership Award

Chicago (Sep. 23, 2019): The Association of Pediatric Hematology/Oncology Nurses (APHON) has awarded this year’s Dr. Patricia Greene Leadership Award to Ruth Anne Herring, MSN RN CPNP-AC/PC CPHON®. Herring was presented with this award at the 43rd...

– Association of Pediatric Hematology/Oncology Nurses (APHON)

Association of Pediatric Hematology/Oncology Nurses Announces Kathleen Ruccione as the winner of the 2019 Dr. Nancy E. Kline Mentoring Award

Chicago (Sep. 23, 2019): The Association of Pediatric Hematology/Oncology Nurses (APHON) has awarded Kathleen Ruccione, PhD MPH RN FAAN CPON®, with the 2019 Dr. Nancy E. Kline Mentoring Award. Lafond’s achievement was formally announced at the 43r...

– Association of Pediatric Hematology/Oncology Nurses (APHON)

Association of Pediatric Hematology/Oncology Nurses Announces Deborah A. Lafond as the 2019 Dr. Casey Hooke Distinguished Service Award Recipient

Chicago (Sep. 23, 2019): The Association of Pediatric Hematology/Oncology Nurses (APHON) has presented Dr. Deborah A. Lafond, DNP PPCNP-BC CHPPN CPON®, with the 2019 Dr. Casey Hooke Distinguished Service Award. Dr. Lafond’s achievement was officia...

– Association of Pediatric Hematology/Oncology Nurses (APHON)

Cancer Researchers at Wake Forest Baptist Receive $25 Million from National Cancer Institute

For the second time in five years, Wake Forest Baptist Health has been recognized for its expertise in conducting innovative cancer care research by the National Cancer Institute’s Community Oncology Research Program (NCORP) with a multimillion-dol...

– Wake Forest Baptist Health

National Cancer Institute's Community Oncology Research Program

Overlook Medical Center Offers “Next Generation” 3-D Technology to Improve Prostate Cancer Diagnosis

Atlantic Health System Cancer Care at Overlook Medical Center is now offering a highly advanced technology that will enhance the ability of physicians to diagnose, stage and treat prostate cancer. The UroNav Fusion Biopsy System fuses pre-biopsy mag...

– Atlantic Health System

Association for Molecular Pathology Announces 2019 Award Recipients

AMP has announced the recipients of this year’s Award for Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership Award and Meritorious Service Award. These prestigious accolades will be presented this November during AMP’s 25th Annual Me...

– Association for Molecular Pathology

Mayo Clinic recebe aprovação da FDA para unidade de detecção avançada de câncer por imagem

A Food and Drug Administration (FDA, Administração de Alimentos e Medicamentos dos EUA) aprovou o uso de uma unidade radioquímica por tomografia de emissão de pósitrons na Mayo Clinic na Flórida.

– Mayo Clinic

La Mayo Clinic obtient l'approbation de la FDA pour son centre d'imagerie avancée de détection du cancer

La Food and Drug Administration (FDA) a approuvé l'utilisation d'une installation de radiochimie à tomographie par émission de positons, également connue sous le nom de cyclotron, à la Mayo Clinic en Floride.

– Mayo Clinic

Mayo Clinic erhält FDA-Zulassung für moderne Bildgebungsanlage zur Krebserkennung

Die Food and Drug Administration (FDA) hat die Verwendung einer Positronen-Emissions-Tomographie-Radiochemie-Anlage, auch Zyklotronanlage genannt, an der Mayo Clinic in Florida genehmigt.

– Mayo Clinic

Mercy’s Hoffberger Breast Center Features New Technology for Early Detection of Lymphedema

The Hoffberger Breast Center at Mercy Medical Center now offers new technology, ImpediMed’s SOZO, a bioimpedance spectroscopy (BIS) device; BIS involves sending a painless electrical current through the body for the purpose of detecting lymphedema....

– Mercy Medical Center, Baltimore

Roswell Park Moving Unique Immunotherapy Platform Forward With $6.42 Million DoD Grant

A team from Roswell Park Comprehensive Cancer Center is moving a new three-part strategy for treating advanced cancers forward with support from a DoD grant that will fund a clinical trial in patients with brain-metastatic breast cancer.

– Roswell Park Comprehensive Cancer Center

Wisconsin Physicians Honored for Cross-Specialty Collaboration to Advance Skin Cancer Treatment

The American Academy of Dermatology has honored dermatologist Gloria Xu, MD, PhD, FAAD, and oncologist Mark Albertini, MD, as Patient Care Heroes for their leadership in launching a melanoma tumor board to optimize care for melanoma patients at the U...

– American Academy of Dermatology





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