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Newswise Special Wire
Tuesday, October 8, 2019

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Newswise Cancer Research Wire for 08-Oct-2019

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Cancer Research

Scientists create brain-mimicking environment to grow 3D tissue models of brain tumors

Researchers developed 3D human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, that includes brain-derived extracellular matrix – providing support for surrounding neural tissue. The development is ...

– Tufts University

Nature Communications; EB002520; NS092857; S10 OD021624766; 1531683

Embargo expired on 04-Oct-2019 at 05:00 ET

Targeting a Novel Regulator of Mitochondrial Cell Death Delivers Anticancer Activity in Preclinical Studies

A novel anticancer molecule created by researchers at The Wistar Institute showed therapeutic activity in preclinical models of various cancer types.

– Wistar Institute

Cancer Research

Embargo expired on 03-Oct-2019 at 10:00 ET

Melanoma Variability at the Single-Cell Level Predicts Treatment Responses, Say Moffitt Researchers

In a new study published in EBioMedicine, researchers with Moffitt Cancer Center’s Donald A. Adam Melanoma and Skin Cancer Center of Excellence reveal that differences at the single-cell level can predict responses to initial BRAF inhibitor therapy...

– Moffitt Cancer Center

EBioMedicine, Oct-2019

Ceevra 3D VR Models Shown to Improve Patient Outcomes in Kidney Cancer Operations

Ceevra, Inc. today announced the publication of a study assessing the impact of using Ceevra’s 3D virtual reality models to plan for operations to remove kidney tumors. The study results, published in JAMA Network Open, showed substantial reduction...

– Ceevra

JAMA Network Open

Bone filler device accelerates bone healing in difficult cases

New approach may boost the bone repair impaired by old age or cancer treatment.

– Michigan Medicine - University of Michigan

Regenerative Medicine

Collagen fibers encourage cell streaming by balancing individual aggression with collective cooperation

Engineers from the McKelvey School of Engineering at Washington University have shown that the length of collagen fibers has a roll to play in the ability of normal cells to become invasive.

– Washington University in St. Louis

Journal of Cell Science; 1R35GM128764-01

Researchers discover critical process for how breast cancer spreads in bones

Researchers from the University of Notre Dame have identified a pair of proteins believed to be critical for spreading, or metastasizing, breast cancer to bone.

– University of Notre Dame

Nature Communications

Cancer patients who exercise have less heart damage from chemotherapy

Sophia Antipolis, 07 October 2019: Patients with cancer should receive a tailored exercise prescription to protect their heart, reports a paper published today in the European Journal of Preventive Cardiology, a journal of the European Society of Car...

– European Society of Cardiology

European Journal of Preventive Cardiology

Large, long-term study suggests link between eating mushrooms and a lower risk of prostate cancer

Results from the first long-term cohort study of more than 36,000 Japanese men over decades suggest an association between eating mushrooms and a lower risk of prostate cancer.

– Tohoku University

International Journal of Cancer

Clues from DNA could help predict growth of prostate cancer

Researchers from the UCLA Jonsson Comprehensive Cancer Center and other institutions in the U.S., Canada, the United Kingdom and Singapore, have identified 1,178 biomarkers in men’s genomes — the complete set of genetic material inherited from o...

– University of California, Los Angeles (UCLA), Health Sciences

NUS scientist designs ‘express courier service’ for immune cells

Dr Andy Tay, a researcher with the National University of Singapore (NUS) who is currently doing his post-doctoral training at Stanford University, has successfully invented a novel transfection method to deliver DNA into immune cells with minimal st...

– National University of Singapore

Microbiome Provides New Clues to Determining Development of Colon Cancer

Findings showcasing a connection between bacteria in the microbiome and colon cancer, which may be used to screen younger populations at risk, were published in the journal Gastroenterology by researchers from the George Washington University.

– George Washington University


Study: Aggressive breast cancers store large amounts of energy, which enables it to spread

Researchers found that aggressive breast cancers store glycogen in very large amounts, offering an explanation of how cells can change their function to evade treatment, grow and spread. Targeting an enzyme involved in this process could potentially ...

– Michigan Medicine - University of Michigan

PLOS ONE; T32CA009676 ; P30CA046592

‘Dietary’ Vulnerability Found in Cancer Cells With Mutated Spliceosomes

A research team from the Johns Hopkins Kimmel Cancer Center reports it has discovered a metabolic vulnerability in multiple types of cancer cells that bear a common genetic mutation affecting cellular machines called spliceosomes. In test tube and mo...

– Johns Hopkins Medicine

The Journal of Clinical Investigation; W81XWH-17-1-0035, K08HL136894

Incidence of Pediatric, Adolescent and Young Adult Head and Neck Melanoma Up 51 Percent in Last Two Decades

Head and neck melanoma among pediatric, adolescent and young adult populations in the United States and Canada increased by 51.1% from 1995 to 2014, per research from Saint Louis University.

– Saint Louis University Medical Center

JAMA Otolaryngology

Patients say ask before using medical records for research

A new study finds that even when patients understand the overall benefit to society, they still want to be able to give consent at least once before their de-identified data is used for research. The feeling was especially strong among racial and eth...

– Michigan Medicine - University of Michigan

Journal of Clinical Oncology; CA201356

Algorithm Reduces Need for Therapy in Children With Intermediate-Risk Neuroblastoma

Roswell Park's Dr. Clare Twist led an effort to develop and validate a new treatment algorithm for infants and children with neuroblastoma. In a new study in the Journal of Clinical Oncology, the team reports that many patients can safely receive les...

– Roswell Park Comprehensive Cancer Center

Journal of Clinical Oncology; U10A180899; U10CA180886

Moffitt Cancer Center Researchers Identify Mechanism Controlling DNA Repair

Moffitt Cancer Center researchers recently identified a new mechanism that controls DNA repair.

– Moffitt Cancer Center

Cell Death & Differentiation, Sept-2019

Study: Biomarker in Urine May Offer Non-invasive Detection of Prostate Cancer

A research study published in the journal Neoplasia and led by principal investigator Nallasivam Palanisamy, Ph.D., associate scientist in the Vattikuti Urology Institute at Henry Ford Health System, has identified a novel prostate cancer gene fusion...

– Henry Ford Health System


Treatment for Incurable Breast Cancer, Melanoma Improved by Adding Local Anesthetics

Results suggest that the combined treatment can lower the effective chemotherapy dosage, reduce side effects, improve tumor cell apoptosis, and reduce tumor cell migration.

– Sbarro Health Research Organization (SHRO)

Journal of Cellular Physiology

Cancer Experts and Features

Greater Understanding of Tumor Cell Biomechanics Could Lead to Improved Treatment

At the cellular level, cancer can be viewed as a mechanical engineering challenge. The disease alters the structure and function of cells and tissues, which are meant to perform very specific tasks.

– National Academy of Sciences (NAS)

World Traveler Is Ready For Next Adventure After Beating Breast Cancer

When Linda Sprick of New Milford, Connecticut, received the news that she had Stage IIA breast cancer, she decided to face her diagnosis head-on and do whatever was necessary to get well. Linda had two lumpectomies at Danbury Hospital, followed by...

– Nuvance Health

3D Mammograms: Are They Worth It?

As 3D mammography, also called digital breast tomosynthesis, has become more available nationwide, a big question many women face is whether they should step up and get one. Are they safe, more effective and for every woman?

Expert Available

– Cedars-Sinai

How Breast Cancer Can Affect Body Image in Young Women

Ted James, MD, Chief of Breast Surgery and Co-Director of the BreastCare Center at Beth Israel Deaconess Medical Center, discusses the unique challenges women in their 20s and 30s face when diagnosed with breast cancer.

Expert Available

– Beth Israel Deaconess Medical Center

Unique Issues for Young Women with Breast Cancer

Monica Valero, MD, a breast surgical oncologist at the BreastCare Center at Beth Israel Deaconess Medical Center, discusses how breast cancer may impact women in their 20s and 30s.

Expert Available

– Beth Israel Deaconess Medical Center

Five Things Women Under 40 Should Know About Breast Cancer

Nadine Tung, MD, head of breast medical oncology and cancer genetics at Beth Israel Deaconess Medical Center, shares 5 things women under 40 should know about breast cancer

Expert Available

– Beth Israel Deaconess Medical Center

Popular Heartburn Medication Recalled For Containing Chemical Linked to Cancer - What You Need to Know and What Can You Take Instead

– Hackensack Meridian Health

Winners of Nobel Prize in medicine tackled fundamental biology function

– Cornell University

Rutgers Experts Available to Discuss Cancer Fears Over Zantac

– Rutgers University-New Brunswick

The Blue in the Pink: Busting Myths about Male Breast Cancer

– University of Nevada, Las Vegas (UNLV)

Can you Avoid Breast Cancer?

M. Michele Blackwood, MD, FACS, chief of breast surgery at Rutgers Cancer Institute of New Jersey and medical director/Northern regional director of breast services at RWJBarnabas Health, shares expertise on breast cancer prevention and advances in b...

– Rutgers Cancer Institute of New Jersey

Cancer Announcements

AACI to Honor Representatives Castor, Upton With Public Service Awards

AACI will present 2019 Public Service Awards to U.S. Representatives Kathy Castor (D-FL) and Fred Upton (R-MI) on Monday, October 21, during the AACI/CCAF Annual Meeting at The Mayflower Hotel in Washington, DC.

– Association of American Cancer Institutes (AACI)

Embargo expired on 02-Oct-2019 at 00:00 ET

William G. Kaelin, MD, of Dana-Farber Cancer Institute wins 2019 Nobel Prize

William G. Kaelin Jr., MD, of Dana-Farber Cancer Institute, has been named a winner of the 2019 Nobel Prize in physiology or medicine.

– Dana-Farber Cancer Institute

NIH Awards $15.2M Grant to UTEP for Biomedical Training

Some of the areas of focus include cancer, addiction, environmental health, health disparities, infectious disease, translational biomedicine, and degenerative and chronic diseases. Its visionary approach addresses individual, psychosocial and instit...

– University of Texas at El Paso

Gregg Semenza Wins 2019 Nobel Prize in Physiology or Medicine For Hypoxia Discovery

Gregg L. Semenza, M.D., Ph.D., whose discoveries on how cells respond to low oxygen levels have the potential to result in treatments for a variety of illnesses, today was awarded the 2019 Nobel Prize in Physiology or Medicine by the Nobel Assembly a...

– Johns Hopkins Berman Institute of Bioethics

Ludwig Oxford’s Sir Peter Ratcliffe Wins Nobel Prize

Ludwig Cancer Research congratulates Peter Ratcliffe on his receipt of the 2019 Nobel Prize for Physiology or Medicine. He was recognized by the Nobel Committee for his landmark discoveries on the mechanisms by which mammalian cells sense and respond...

– Ludwig Cancer Research

Lung Cancer Program at NYU Langone Health’sPerlmutter Cancer Center Joins PrestigiousThoracic Surgery Oncology Group

NYU Langone Health has become one of 23 institutions selected to comprise the American Association for Thoracic Surgery’s Thoracic Surgery Oncology Group (TSOG). A North American thoracic surgery clinical trials network, TSOG aims to improve the u...

– NYU Langone Health

ASTRO honors 2019 Gold Medalists, Honorary Member and other award recipients

The American Society for Radiation Oncology (ASTRO) recognized the recipients of its 2019 Gold Medal awards and other high-profile honors at the 61st ASTRO Annual Meeting in Chicago. View/download photos from the September 17 awards ceremony online. ...

– American Society for Radiation Oncology (ASTRO)

Stopping the Spread of Cancer

University of Utah biomedical engineering assistant professor Tara Deans has received this year’s National Institutes of Health Director’s New Innovator Award and a $1.5 million grant to develop a method that could help stop the spread of cancer ...

– University of Utah





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