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Newswise Special Wire
Tuesday, November 5, 2019

Public edition |

Newswise Cancer Research Wire for 05-Nov-2019

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Black and Elderly Patients Less Likely to Receive Lung Cancer Treatments

Only about 6 in 10 lung cancer patients in the United States receive the minimal lung cancer treatments recommended by the National Comprehensive Cancer Network guidelines, according to new research published online in the Annals of the American Thor...

– American Thoracic Society (ATS)

Annals of the American Thoracic Society

Embargo expired on 01-Nov-2019 at 00:15 ET

Common early sign of cardiovascular disease also may indicate cancer risk, study finds

A Mayo Clinic-led study involving 488 cardiac patients whose cases were followed for up to 12 years finds that microvascular endothelial dysfunction, a common early sign of cardiovascular disease, is associated with a greater than twofold risk of can...

– Mayo Clinic

European Journal of Preventive Cardiology

Embargo expired on 31-Oct-2019 at 08:00 ET

Yale Cancer Center study shows checkpoint inhibitor prolongs survival in patients with certain head and neck cancers

The checkpoint inhibitor pembrolizumab (Keytruda) offers patients with advanced head and neck cancers longer survival time, according to a new global study led by Yale Cancer Center (YCC).

– Yale Cancer Center

The Lancet

Embargo expired on 31-Oct-2019 at 19:30 ET

Study finds racial disparities in culturally competent cancer care

Many non-white minority cancer survivors place importance on seeing doctors who share or understand their culture, but are less likely than non-Hispanic whites to be able to see such physicians, according to a new study from Dana-Farber Cancer Instit...

– Dana-Farber Cancer Institute

JAMA Oncology, Oct. 31 2019

Embargo expired on 31-Oct-2019 at 11:00 ET

3D brain tissue system aids study of deadly tumor progression

Made with extracellular matrix (ECM) from pig brains and seeded with tumors from patients, the system is revealing tumor/ECM interactions that aid tumor growth, providing potential targets for new therapies.

– National Institute of Biomedical Imaging and Bioengineering

Nat Comm, Oct-2019; EB002520

Updated Report on Trends in Global PD-1/PD-L1 Immunotherapy Clinical Development from the Cancer Research Institute Published in Nature Reviews Drug Discovery

Latest analysis of the global PD-1/PD-L1 immunotherapy clinical development pipeline reveals dramatic growth over past two years in number of trials, drug combinations, and drug targets, but lower patient recruitment rates in the U.S. compared to Chi...

– Cancer Research Institute

Nature Reviews Drug Discovery, 4 Nov 2019

Fluorescent probes offer fuller view of drug delivery in cells

Selecting the most effective molecules for drug delivery is often a trial-and-error process, but Cornell engineers are providing some precision thanks to a technique that reveals the performance of those molecules inside living cells.

– Cornell University

Cell Chemical Biology

Marker reveals if benign-appearing meningiomas are perilous

A modified protein in benign-appearing meningiomas can reveal which are truly benign and which are more dangerous and require more aggressive treatment, researchers have discovered.

– University of Washington School of Medicine

Journal of Clinical Cancer Research

Moffitt Researchers Identify a Mechanism Controlling Tumor Cell Recognition by Immune Cells

Immunotherapy has become a standard treatment approach for several types of cancer, including melanoma. However, tumors can escape immune cell detection even with the use of immunotherapies. In a new study published in Cancer Immunology Research, Mof...

– Moffitt Cancer Center

Cancer Immunology Research, Nov-2019

Chemotherapy sometimes set the stage for drug-resistant leukemia at relapse

An international collaboration has identified therapy-induced, drug-resistance mutations in children with acute lymphoblastic leukemia who relapse

– St. Jude Children's Research Hospital

Blood, Published Oct. 24, 2019

Kidney Cancer Study Uncovers New Subtypes and Clues to Better Diagnosis and Treatment

In what is believed to be the most comprehensive molecular characterization to date of the most common — and often treatment-resistant — form of kidney cancer, researchers at Johns Hopkins’ departments of pathology and oncology, Johns Hopkins K...

– Johns Hopkins Medicine

Cell; U24CA210985

Complex Cellular Machine Visualized to Yield New Insights in Cancer

Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. Now, for the first time, scientists have developed a high-resolution visual map of this multi-protein machine, elucidat...

– Huntsman Cancer Institute at the University of Utah


It takes more than a catchy headline for health awareness campaigns to inspire action

A Keck School of Medicine of USC study compared the Pinktober and Movember movements, showing that reach and engagement do not always lead people to research screening options

– Keck Medicine of USC

Lancet Oncology

New research suggests proton radiation therapy can benefit patients with challenging liver tumors

Two new studies support and inform the use of proton radiation therapy to treat patients with hepatocellular carcinoma (HCC), a common but often fatal type of liver cancer for which there are limited treatment options. The studies were published in t...

– American Society for Radiation Oncology (ASTRO)

International Journal of Radiation Oncology*Biology*Physics, Sep-2019; International Journal of Radiation Oncology*Biology*Physics, Sep-2019; International Journal of Radiation Oncology*Biology*Physics, Sep-2019...

Cyp2F2-Mediated Lung Cancer, Rapid Risk Assessment of Color Additives, and More Featured in November 2019 Toxicological Sciences

Toxicological Sciences continues to deliver cutting-edge research in toxicology in the November 2019 issue. This issue features research on computational toxicology and databases, developmental and reproductive toxicology, and more.

– Society of Toxicology

Toxicological Sciences

Researchers investigate impact of actual and virtual nature on cancer patients

Researchers at Houston Methodist Cancer Center are exploring whether exposure to nature, through either a live garden or virtual reality, can alleviate pain and distress in cancer patients undergoing chemotherapy, possibly reducing the need for presc...

– Houston Methodist

Cancer Experts and Features

LLNL leads multi-institutional team in modeling protein interactions tied to cancer

Computational scientists, biophysicists and statisticians from Lawrence Livermore National Laboratory (LLNL) and Los Alamos National Laboratory (LANL) are leading a massive multi-institutional collaboration that has developed a machine learning-based...

– Lawrence Livermore National Laboratory

2019 Supercomputing Conference

Human Immune Monitoring Center at Mount Sinai to analyze the effectiveness of a novel cancer therapy drug

The Human Immune Monitoring Center (HIMC) at the Icahn School of Medicine at Mount Sinai will apply cutting-edge high-throughput technologies to evaluate the therapeutic effects of Libtayo® (cemiplimab-rwlc), a PD-1 antibody blockade developed by bi...

– Mount Sinai Health System

Smilow Cancer Hospital expert explains five things you need to know about Lung Cancer

Roy Herbst, M.D., Ph.D., chief of Medical Oncology at Smilow Cancer Hospital, has been researching lung cancer and treating patients with the disease for more than 25 years. He discusses the facts about lung cancer, ways to reduce your risk, and how ...

– Yale Cancer Center

What you need to know about pancreatitis

Pancreatitis causes more than 360,000 hospitalizations each year. Sajan Nagpal, MD, a medical pancreatologist at the University of Chicago Medicine, answers common questions about this painful condition.

– University of Chicago Medical Center

Atlantic Health System Cancer Care Enrolling Patients in Innovative Pancreatic Cancer Clinical Trials

November is national Pancreatic Cancer Awareness month. This year alone, more than 56,000 Americans will be diagnosed with pancreatic cancer. Pancreatic tumors are particularly aggressive and hard to treat "due to a mutational profile that makes it...

– Atlantic Health System

ASTRO supports nomination of Dr. Stephen Hahn to lead U.S. Food and Drug Administration

The American Society for Radiation Oncology (ASTRO) today expressed strong support for the nomination of radiation oncologist Stephen Hahn, MD, FASTRO, as Commissioner of the Food and Drug Administration (FDA). Dr. Hahn served on the ASTRO Board of D...

– American Society for Radiation Oncology (ASTRO)

GW Experts Are Available to Speak for Stories during Lung Cancer Awareness Month

– George Washington University

November is Lung Cancer Awareness Month

Experts from the Rutgers Tobacco Dependence Program share more about the causes and risk factors for lung cancer, which include smoking. At focus is prevention, including tobacco cessation.

– Rutgers Cancer Institute of New Jersey

Men can get breast cancer, too

Roland Taylor, 69, has faced considerable struggles in life, at times battling homelessness and addiction. Two years ago, he felt a lump in his chest, but ignored it until he discovered that it had grown. He went to the doctor and was shocked to lea...

– UW Medicine

Cancer Announcements

MD Anderson and Takeda Announce Collaboration to Accelerate the Development of Clinical-Stage, Off-The-Shelf CAR NK-Cell Therapy Platform

MD Anderson and Takeda today announced an exclusive license agreement and research agreement to develop CAR NK-cell therapies for the the treatment of B-cell malignancies.

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 05-Nov-2019 at 07:00 ET

Nashville Predators to Honor Late CEO of Monroe Carell Jr. Children’s Hospital at Vanderbilt at Hockey Fights Cancer Game

When the Nashville Predators hockey team hits the ice Saturday, Nov. 2, the players will take on an important opponent: childhood cancer. The Hockey Fights Cancer game against the New York Rangers will raise funds for the 365 Pediatric Cancer Fund...

– Vanderbilt University Medical Center

New Nursing Leader Named to Rutgers Cancer Institute of New Jersey and RWJBarnabas Health

Reaffirming its commitment to continued growth and excellence, Rutgers Cancer Institute of New Jersey and RWJBarnabas Health welcome Carolyn Hayes, PhD, RN, NEA-BC, as the new Chief Nursing Officer, RWJBarnabas, Oncology Services and Rutgers Cancer I...

– Rutgers Cancer Institute of New Jersey

Cutler Family gifts $15 million to University Hospitals to transform men’s health care

Announcement of a new $15 million gift for University Hospitals to develop a new model for the delivery of health care to men.

– University Hospitals Cleveland Medical Center

Medicine, Media & Patients: A New Professional Language

Panel to Convene at Annual Medical conference at NIAF

– Sbarro Health Research Organization (SHRO)

Medicine, Media, and Patients: a new professional language

Prostate Cancer Research Gala Recognizes Innovations in Treatment and Patient Care

Atlanta Falcons and Atlanta United owner Arthur Blank and Nina Bhardwaj, MD, PhD, will be honored for their contributions to prostate cancer research.

– Mount Sinai Health System

New NCCN Guidelines Debut to Manage Complications and Improve Readiness for Stem Cell Transplant Recipients

The National Comprehensive Cancer Network (NCCN) published new NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Hematopoietic Cell Transplantation, (aka stem cell transplant or bone marrow transplant), with step-by-step information...

– National Comprehensive Cancer Network® (NCCN®)

NCCN Guidelines

Collaboration with Texas Biomed, SwRI and UT Health San Antonio targets Bladder Cancer

The San Antonio Medical Foundation (SAMF) has awarded Texas Biomedical Research Institute Professor Jordi B. Torrelles, Ph.D., with a $173,000 grant to study a modified Mycobacterium bovis Bacillus Calmette et Guérin (BCG) vaccine shown to have prom...

– Texas Biomedical Research Institute

New $5.7 Million Grant Aims to Increase Colorectal Cancer Screening, Follow-Up Care in Appalachia

Cancer-control researchers at the University of Kentucky Markey Cancer Center and The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) aim to increase c...

– University of Kentucky

Cancer Research

Fatty Acid Derivative Triggers Death of Colorectal Cancer Cells, Study Finds

– American Physiological Society (APS)

American Journal of Physiology - Cell Physiology





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