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Newswise Special Wire
Tuesday, December 24, 2019

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Newswise Cancer Research Wire for 24-Dec-2019

Researchers identify immune-suppressing target in glioblastoma

Researchers at The University of Texas MD Anderson Cancer Center have identified a tenacious subset of immune macrophages that thwart treatment of glioblastoma with anti-PD-1 checkpoint blockade, elevating a new potential target for treating the almo...

– University of Texas M. D. Anderson Cancer Center

Nature Medicine

Embargo expired on 23-Dec-2019 at 11:00 ET

Finding Familiar Pathways in Kidney Cancer

The famous cancer gene p53, which was thought to be less relevant in kidney cancer, may play a larger role than previously appreciated, suggesting new potential for treatment.

– Thomas Jefferson University

Nature Communications (DOI: 10.1038/s41467-019-13608-1, 2019)

Embargo expired on 20-Dec-2019 at 05:00 ET

Researchers Identify Potential Formula for Blood Cancer Vaccine

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study published in Clinical Cancer...

– Mount Sinai Health System

Clinical Cancer Research

Embargo expired on 19-Dec-2019 at 11:00 ET

New Pediatric Cancer Guidelines Published by National Comprehensive Cancer Network Focus on Improving Long-Term Outcomes Worldwide

NCCN publishes new NCCN Guidelines for treating children, adolescents and young adults with pediatric aggressive mature B-cell lymphomas (common and curable forms of non-Hodgkin lymphoma), including Burkitt lymphoma and diffuse large B-cell lymphoma....

– National Comprehensive Cancer Network® (NCCN®)

Embargo expired on 18-Dec-2019 at 08:50 ET

Many younger patients with stomach cancer have a distinct disease, Mayo research discovers

Many people under 60 who develop stomach cancer have a "genetically and clinically distinct" disease, new Mayo Clinic research has discovered. Compared to stomach cancer in older adults, this new, early onset form often grows and spreads more quickly...

– Mayo Clinic


Muchos pacientes jóvenes con cáncer de estómago tienen enfermedad diferenciada, descubren investigadores de Mayo Clinic

Muchas personas menores de 60 años con cáncer de estómago tienen una enfermedad “diferenciada genética y clínicamente”, descubrió un nuevo estudio de Mayo Clinic. Comparado con el cáncer de estómago en adultos de más edad, este nuevo tip...

– Mayo Clinic


Investigadores de Mayo Clinic presentan resultados durante Simposio de Cáncer Mamario 2019 en San Antonio

Los investigadores de Mayo Clinic presentaron sus resultados durante el Simposio de Cáncer Mamario, realizado entre el 10 y el 14 de diciembre en San Antonio.

– Mayo Clinic

باحثو Mayo Clinic يقدمون نتائج في ندوة سان أنطونيو لسرطان الثدي لعام 2019

قدم باحثو Mayo Clinic نتائج في ندوة سان أنطونيو لسرطان الثدي التي عُقدت في سان أنطونيو في الفترة من 10 إلى 14 ديسمبر الجاري.

– Mayo Clinic

Pesquisadores da Mayo Clinic apresentam seus achados no Simpósio de Câncer de Mama de 2019 em San Antonio

Pesquisadores da Mayo Clinic apresentaram seus achados no Simpósio de Câncer de Mama de San Antonio, realizado nos dias 10 a 14 de dezembro.

– Mayo Clinic

Des chercheurs de Mayo Clinic présentent leurs résultats à l’occasion du San Antonio Breast Cancer Symposium 2019

Des chercheurs de Mayo Clinic ont présenté leurs conclusions lors du San Antonio Breast Cancer Symposium, qui s’est déroulé du 10 au 14 décembre à San Antonio.

– Mayo Clinic

San Antonio Breast Cancer Symposium, December 10-14

Forscher von Mayo Clinic präsentieren Ergebnisse auf dem San Antonio Breast Cancer Symposium 2019

Forscher von Mayo Clinic haben ihre Ergebnisse auf dem San Antonio Breast Cancer Symposium vorgestellt, das vom 10. bis 14. Dezember in San Antonio stattgefunden hat.

– Mayo Clinic

Breaking the dogma: Key cell death regulator has more than one way to get the job done

Scientists at St. Jude Children’s Research Hospital have discovered a new way that the molecule RIPK1 leads to cell death in infected, damaged or unwanted cells showing that more than one mechanism can trigger the process. The findings appeared onl...

– St. Jude Children's Research Hospital

Journal of Experimental Medicine

Mayo Clinic 研究人员在2019年圣安东尼奥乳腺癌研讨会上公布研究成果

圣安东尼奥乳腺癌大会(SABCS)于12月10日至14日举行,Mayo Clinic的研究人员在会上公布了他们的研究成果。

– Mayo Clinic

Strongest Link Yet Between Nitrites and Cancer - but ‘Not All Processed Meat Has Same Risk’

Researchers from Queen’s University Belfast have questioned the World Health Organisation’s blanket classification of processed meat as carcinogenic after finding significant evidence gaps between processed meat treated with nitrites and nitrite-...

– Queen's University Belfast


New Therapeutic Strategy for Chemotherapy Resistance in Ovarian Cancer

A Wistar study demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of stem-like chemoresistant cells following cisplatin treatment.

– Wistar Institute

Cancer Research

Opioid Self-management Practices and Potential Safety Risks Among Patients with Cancer

Despite a national opioid crisis, prescribed opioid analgesics remain a viable option for pain management for patients with cancer. In effect, patients with cancer represent one of the few groups excluded from most state legislation and policy initi...

– University of Pennsylvania School of Nursing

Journal of Pain; ACS #128779-PEP-15-186-01

Penn Researchers Predict 10-Year Breast Cancer Recurrence with MRI Scans

MRI and an emerging field of medicine called radiomics could help to characterize the heterogeneity of cancer cells within a tumor and allow for a better understanding of the causes and progression of a person’s individual disease, according to a P...

– Perelman School of Medicine at the University of Pennsylvania

Clinical Care Research, Nov-2019

Cancer therapy may be aided by induced macropinocytosis, a rarely reported form of cell death

A metabolic inhibitor was able to kill human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route — catastrophic macropinocytosis. The inhibitor acted synergistically with the chemotherapy drug, cyclophospha...

– University of Alabama at Birmingham

ES026219 ; Proceedings of the National Academy of Sciences

CRI scientists discover metabolic feature that allows melanoma cells to spread

Researchers at Children’s Medical Center Research Institute at UT Southwestern (CRI) have uncovered why certain melanoma cells are more likely to spread through the body.

– UT Southwestern Medical Center


Science Snapshots From Berkeley Lab

This edition of Science Snapshots highlights the discovery of an investigational cancer drug that targets tumors caused by mutations in the KRAS gene, the development of a new library of artificial proteins that could accelerate the design of new mat...

– Lawrence Berkeley National Laboratory

Nature, Oct-30-2019; Chemical Science; Nature Communications

BIDMC’s Research & Health News Digest: December 2019

A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.

– Beth Israel Deaconess Medical Center

A Decade in Review: 7 Healthcare Breakthroughs

UCLA Health experts weigh in on the most significant healthcare advances of the last ten years and what exciting developments we can look forward to in the decade ahead.

– University of California, Los Angeles (UCLA), Health Sciences

AACI Supports NIH, NCI Funding Increases in Federal Budget

The Association of American Cancer Institutes (AACI) applauds the budget deal passed by Congress for Fiscal Year 2020.

– Association of American Cancer Institutes (AACI)

Clinical trials planned for brain tumor ‘GPS’ maps

A GPS map to guide neural navigation devices developed by a Case Western Reserve University cancer researcher has shown 90% accuracy in pinpointing brain tumors and will soon be tested in real time with patients at Cleveland Clinic under a three-yea...

– Case Western Reserve University

Backed by Yale Cancer Center research, FDA approves new drug for advanced bladder cancer

The U.S. Food & Drug Administration (FDA) granted accelerated approval to the drug enfortumab vedotin (EV) to treat adult patients with advanced urothelial or bladder cancer.

– Yale Cancer Center

American Society of Clinical Oncology (ASCO) annual meeting

The Wistar Institute Received Nearly $2.5M in Philanthropic Support

In the past six months, scientists at The Wistar Institute received funding from private foundations totaling $2,418,000 that will fuel new discoveries in cancer, immunology and infectious diseases.

– Wistar Institute

Case Western Reserve researchers to lead Northeast Ohio initiative to prevent, detect and treat lung cancer in underserved communities

With a $2.75 million, three-year grant from the Bristol-Myers Squibb (BMS) Foundation, researchers from Case Western Reserve University will lead a community wide initiative to create and apply innovative methods to prevent and detect lung cancer in ...

– Case Western Reserve University

Bonni Lee Guerin, MD Honored By American Cancer Society - Northeast Region

Bonni Lee Guerin, MD, hematologist/oncologist and physician researcher at Overlook Medical Center, was honored by the American Cancer Society for her role in advancing breast cancer treatment and prevention. In addition to her forward-looking clinic...

– Atlantic Health System

ASCO elects UChicago Medicine's Vokes as president-elect

The American Society of Clinical Oncology (ASCO) has elected Everett Vokes, MD, Chair of the Department of Medicine at the University of Chicago Medicine, to serve as its president for the 2021-22 term and Tara Henderson, MD, MPH, Associate Professor...

– University of Chicago Medical Center

Microscopic World Comes Alive During Nikon Small World Exhibit

See cellular images as distinct as abstract art, minerals appear as future urban landscapes, single-celled organisms of the microscopic netherworld, and much more from the 2019 Nikon Small World competition of photomicrography.

– Wistar Institute

SLAS Discovery Releases First Edition of 2020


SLAS Discovery





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