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Newswise Special Wire
Tuesday, January 14, 2020

Public edition |

Newswise Cancer Research Wire for 14-Jan-2020

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Cancer Research

Elevated Leukemia Incidence Is Found in World Trade Center Rescue and Recovery Workers

Responders who worked at the World Trade Center site after the attacks on September 11, 2001, have an increased overall cancer incidence compared to the general population, particularly in thyroid cancer, prostate cancer, and, for the first time ever...

– Mount Sinai Health System

JNCI Cancer Spectrum

Embargo expired on 14-Jan-2020 at 00:05 ET

Investigational drugs block bone loss in mice receiving chemotherapy

Studying mice, researchers from Washington University School of Medicine in St. Louis have found a driver of bone loss related to cancer treatment — cellular senescence. This process is independent of hormones related to bone health, such as estrog...

– Washington University in St. Louis

Cancer Research; P30 AR074992; NS086741 ; P30 CA91842; CDI-CORE-2015-505

Embargo expired on 13-Jan-2020 at 10:00 ET

Updated Breast Cancer Guideline Refines Testing to Better Identify Patients Likely to Benefit from Treatment

The College of American Pathologists (CAP) and the American Society of Clinical Oncology (ASCO),have updated the guideline for estrogen and progesterone receptor (ER/PgR) testing in breast cancer.

– College of American Pathologists (CAP)

Archives of Pathology & Laboratory Medicine; Journal of Clinical Oncology

Embargo expired on 13-Jan-2020 at 13:30 ET

NUS researchers discover breakthrough in cancer diagnosis using big data analytics

A team of researchers from the National University of Singapore has developed a personalised assessment tool which can detect the incidence of cancer, predict patient survivability and determine patient suitability for immunotherapy cancer treatment....

– National University of Singapore

Proceedings of the National Academy of Sciences; Nature Partner Journal’s Precision Oncology

Large Study of Subtle, Rare Genetic Differences Reveals Several New Clinically Relevant Targets for Variety of Diseases

A large, multicenter study led by researchers at Children’s Hospital of Philadelphia (CHOP) compared the genomic data of more than 100,000 people of European ancestry and discovered how relatively rare, albeit recurrent, genetic variations can infl...

– Children's Hospital of Philadelphia

Nature Communications, Jan-2019

Scientists identify protein associated with ovarian cancer that exacerbates neurodegeneration in Alzheimer’s

Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer’s disease, by combining computational methods and lab research.

– Houston Methodist

EBioMedicine, Jan. 2020

How Marijuana Accelerates Growth of HPV-related Head and Neck Cancer Identified

University of California San Diego School of Medicine researchers identified how THC from marijuana accelerates cancer growth in patients with human papillomavirus (HPV)-positive head and neck cancer.

– University of California San Diego Health

Clinical Cancer Research

Fighting melanoma with zebrafish: Biologists in search of a powerful combination of cancer-fighting drugs

Northern Arizona University professor Matthew Salanga is leading an 18-month project, funded by the Flinn Foundation, in search of drugs to help fight the deadliest form of skin cancer.

– Northern Arizona University

John Theurer Cancer Center Investigators Report Effectiveness of New Treatment for Refractory Multiple Myeloma

Investigators at John Theurer Cancer Center at Hackensack University Medical Center in New Jersey were part of the CANDOR global phase III clinical trial for patients with refractory (persistent) multiple myeloma. The study was selected as the presti...

– Hackensack Meridian Health

61st American Society of Hematology (ASH) Annual Meeting

Researchers create framework for evaluating how fast a cancer will grow

An international team of researchers led by UCLA’s Paul Boutros, have created a new way to accurately estimate how fast an individual cancer is evolving using open-source software.

– University of California, Los Angeles (UCLA), Health Sciences

Nature Biotechnology

U-M researchers find new function for macropinocytosis in mammalian cell growth

For the first time, researchers at Michigan Medicine have demonstrated that macropinocytosis, a cellular process known to be involved in cancer and other diseases, also plays an important role in the growth of at least one type of normal mammalian ce...

– Michigan Medicine - University of Michigan

Nature Communications

Moffitt Researchers Identify Molecular Characteristics of Leptomeningeal Melanoma Metastases

Very little information is known about the molecular development of leptomeningeal melanoma metastases (LMM), making it difficult to develop effective therapies. Researchers in Moffitt Cancer Center’s Donald A. Adam Melanoma and Skin Cancer Center...

– Moffitt Cancer Center

Clinical Cancer Research, Jan-2020

Study finds 95 percent satisfaction rate with Mohs surgery

Survey of more than 40 UT Southwestern patients reveals positive outcomes

– UT Southwestern Medical Center

Dermatologic Surgery

Online Educational Videos Boost Cancer Knowledge

Education videos distributed on social media can reduce barriers related to health literacy and improve health in underserved populations, according to Rutgers researchers

– Rutgers University-New Brunswick

Journal of Cancer Education; P30CA072720, K22CA197066

Surgery May Add Months or Years of Survival For Adults With Rare And Deadly Brain Cancers

For adult patients with brainstem high-grade gliomas — one of the rarest and deadliest forms of brain cancer — surgically removing the entire tumor may add many months or potentially years of survival beyond that offered by radiation and chemothe...

– Johns Hopkins Medicine

Journal of Neuro-Oncology

New research identifies obstacles to early detection of skin cancer in rural western states

Residents of rural, sparsely-populated "frontier counties" in the Western U.S. face higher incidents of skin cancer and related mortality rates.

– Texas State University

Psychology, Health and Medicine

Mesothelioma Linked to Asbestos in Talcum Powder

Thirty-three cases of the asbestos-related lung cancer mesothelioma draw attention to talcum powder as a non-occupational source of exposure to asbestos, according to a study in the January Journal of Occupational and Environmental Medicine.

– Wolters Kluwer Health: Lippincott Williams and Wilkins

Journal of Occupational and Environmental Medicine

Lack of insurance cause of survivorship gap in minorities with cancer, study shows

Nearly half of the disparity in later-stage diagnosis was mediated by being uninsured or underinsured, according to a new study conducted at the University of Illinois at Chicago and Boston Medical Center/Boston University School of Medicine.

– University of Illinois at Chicago

JAMA Oncology

Study finds salt nanoparticles are toxic to cancer cells

A new study at the University of Georgia has found a way to attack cancer cells that is potentially less harmful to the patient.

– University of Georgia

Advanced Materials

First-Ever Genomic Study of Puberty Yields Insights into Development, Cancer, and Infertility

In the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) outline distinct and critical changes to stem cells in males during adolescence.

– Huntsman Cancer Institute at the University of Utah

Cell Stem Cell

Researchers Surprised by High Levels of Alcohol Consumption among Cancer Survivors

New research JNCCN—Journal of the National Comprehensive Cancer Network, using data from NHIS to examine self-reported drinking habits among people reporting a cancer diagnosis, finds 56.5% were current drinkers, 34.9% exceeded moderate drinking le...

– National Comprehensive Cancer Network® (NCCN®)

JNCCN—Journal of the National Comprehensive Cancer Network

Patient step counts predict lung cancer treatment outcomes, study finds

Numerous studies have shown that monitoring physical activity promotes better health – from reducing body mass index to watching for signs of hypertension, for example. A new study suggests step counters could play yet another role: predicting outc...

– American Society for Radiation Oncology (ASTRO)

International Journal of Radiation Oncology * Biology * Physics, Nov-2019

Plant-derived SVC112 hits cancer stem cells, leaves healthy cells alone

Study shows Colorado drug SVC112 stops production of proteins that cancer stem cells need to survive and grow

– University of Colorado Cancer Center

Cancer Research

Common Indian Fruit Shows Promise as a Cancer Fighter

According to recent research, the Asian fruit commonly eaten in India that also is known as bitter melon has properties that prevent cancer from growing and spreading. It also shows promise in slowing the progression of cancer, which is the world’s...

– Saint Louis University

Cell Communication and Signalling, Oct. 21, 2019; Cancer Prevention Research, Jan. 11, 2018

U-M Team Sheds New Light on the Role of Regulatory T Cells in Pancreatic Cancer

A multidisciplinary Michigan Medicine team is shedding new light on the role of regulatory T cells in pancreatic cancer — and, in mouse models, have uncovered a new potential target to improve immunotherapy approaches to the deadly disease.

– Michigan Medicine - University of Michigan

Cancer Discovery

Natural Extract to Counter Nephrotoxicity Induced by Mycotoxin OTA

Today a team of researchers from the Department of Veterinary Medicine and Animal Production of the Federico II University of Naples, in collaboration with the Sbarro Health Research Organization (SHRO), at Temple University in Philadelphia, and the ...

– Sbarro Health Research Organization (SHRO)

Journal of Cellular Physiology

Young Women Still May Be Getting Unnecessary Pelvic Exams

Pelvic examinations and cervical cancer screenings are no longer recommended for most females under age 21 during routine health visits, but a new study has found that millions of young women are unnecessarily undergoing the tests, which can lead to ...

– UCSF Helen Diller Family Comprehensive Cancer Center

JAMA Intern Med. Published online January 6, 2020.

Mayo Clinic研究发现,许多较年轻的胃癌患者有独特的疾病特征

Mayo Clinic的一项新研究发现,许多60岁以下的胃癌患者的疾病“在基因和临床上均具有独特性”。该研究发现,与年长患者所患有的胃癌相比,这种新的早发性胃癌,其生长和扩散速度通常更...

– Mayo Clinic


Discoveries detail role of stem cell in deadly gastric cancer

A Cornell study provides important new insights into a common and deadly type of gastric cancer.

– Cornell University

Nature Communications

Tip Sheet: Mesh loaded with T cells shrinks tumors; second dose of CAR-T cells shows potential; and gene-edited cells stay safe as immunotherapy attacks cancer

Below are summaries of recent Fred Hutch research findings with links for additional background and media contacts.

– Fred Hutchinson Cancer Research Center

JCI Insight; Nature Biomedical Engineering; 2019 American Society of Hematology annual meeting; ASH meeting

Shedding light on pancreatic neuroendocrine tumors

The University of Chicago Medicine's Xavier Keutgen, MD, one of the few surgeons in the country with advanced expertise in extensive removal of neuroendocrine tumors, talks about this rare disease.

– University of Chicago Medical Center

Cancer Research Alerts

Nanoparticles Deliver ‘Suicide Gene’ Therapy to Pediatric Brain Tumors Growing in Mice

Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a “suicide gene” to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ester) nanopar...

– Johns Hopkins Medicine

Nanomedicine: Nanotechnology, Biology and Medicine

Cancer Experts and Features

January Is Thyroid Awareness Month

Mount Sinai Doctors Offer Unique Procedures for Thyroid Nodules and Stress Importance of Early Detection

– Mount Sinai Health System

Expert Offers Insight on Sneaky Signs of Cervical Cancer

– Mercy Medical Center

Cancer Announcements

Mayo Clinic, en colaboración con Helix, hará secuenciación en cien mil participantes para crear base de datos genómicos

Mayo Clinic está creando una biblioteca de datos con la secuenciación genómica de cien mil participantes que dieron su autorización para el efecto, a fin de avanzar en la investigación y en la atención médica de los pacientes.

– Mayo Clinic

Lung Cancer Expert to Head Medical Oncology at Cedars-Sinai

Prominent lung cancer expert Karen L. Reckamp, MD, MS, has been selected to be director of the Division of Medical Oncology at Cedars-Sinai Cancer. Reckamp also will serve as medical oncology director of the Women's Guild Lung Institute in Cedars-Sin...

– Cedars-Sinai

Douglas Hanahan Appointed Distinguished Scholar of the Ludwig Institute for Cancer Research

Ludwig Cancer Research is pleased to announce the appointment of Douglas Hanahan as a Distinguished Scholar at the Lausanne Branch of the Ludwig Institute for Cancer Research.

– Ludwig Cancer Research

Dana-Farber Cancer Institute to Establish Riney Family Multiple Myeloma Initiative

Dana-Farber Cancer Institute will establish the Riney Family Multiple Myeloma Initiative to help improve outcomes and accelerate understanding of the underlying biology for the most challenging types of myelomas, cancers that form in a type of white ...

– Dana-Farber Cancer Institute

Brain Cancer Expert Joins Neurosurgery Faculty at Mount Sinai

Dolores Hambardzumyan, PhD, MBA, has been appointed Senior Faculty in the Department of Neurosurgery and a member of The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

– Mount Sinai Health System

Grant to help UniSA researchers develop personalised cancer treatment

Personalised cancer treatment is one step closer to becoming a reality for more patients, thanks to a Cancer Council Beat Cancer Project grant awarded to University of South Australia researcher Dr Stephanie Reuter Lange to explore how computer-based...

– University of South Australia

Mougalian appointed Deputy Chief Ambulatory Officer at Smilow Cancer Hospital

Sarah Mougalian, M.D., assistant professor of Medicine (Medical Oncology) has been named the inaugural Deputy Chief Ambulatory Officer at Smilow Cancer Hospital (SCH) at Yale New Haven Hospital.

– Yale Cancer Center

Sanft named Chief Patient Experience Officer at Smilow Cancer Hospital

Tara Sanft, M.D., associate professor of Medicine (Medical Oncology) and Director of the Smilow Cancer Hospital (SCH) Survivorship Clinic, has been appointed the inaugural Chief Patient Experience Officer at Yale Cancer Center (YCC) and SCH at Yale N...

– Yale Cancer Center

Ping-Chih Ho Appointed Associate Member of Ludwig Institute for Cancer Research

Ludwig Cancer Research congratulates Ping-Chih Ho on his appointment as Associate Member at the Lausanne Branch of the Ludwig Institute for Cancer Research.

– Ludwig Cancer Research

University of Colorado Cancer Center named National Pancreas Foundation Center of Excellence

Due in part to advanced surgical techniques, more effective medicines, and a multidisciplinary approach to treating the disease, University of Colorado Cancer Center is able to operate on 30+ percent of pancreatic cancer patients, nearly double the n...

– University of Colorado Cancer Center

John Theurer Cancer Center Announces Appointment of Five New Physicians

Five new physicians have joined the medical staff at John Theurer Cancer Center at Hackensack University Cancer Center in New Jersey:

– Hackensack Meridian Health

Media registration open for ENDO 2020

Members of the media can now register to cover the latest advances in hormone health and science at ENDO 2020. The Endocrine Society’s annual meeting will be held March 28-31, 2020 in San Francisco, Calif.

– Endocrine Society

Cancer Researcher Receives OU’s First National Institutes of Health MERIT (R37) Award

The quest to conquer cancer is motivating a team of researchers at the University of Oklahoma to develop a 3D scanner capable of guiding the radiation treatment, dispensing just the right amount of radiation to just the precise location, making real-...

– University of Oklahoma, Gallogly College of Engineering






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