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Newswise Special Wire
Tuesday, March 24, 2020

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Newswise Cancer Research Wire for 24-Mar-2020

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Cancer Research

3D Genetic Structure in Blood Cancer Important Beyond DNA Code Changes

Children with aggressive blood cancers have differences — not just in the DNA code of their blood cells — but also in the heavily twisted protein superstructure that controls access to genes.

– NYU Langone Health

Nature Genetics; P01 CA229086, R01 CA228135, R01 CA216421, R01 CA202025, R01 CA133379, R01 CA149655, R01 CA194923, R01 CA188293

Embargo expired on 23-Mar-2020 at 12:00 ET

Study sheds light on fatty acid’s role in “chemobrain” and multiple sclerosis

A study led by The University of Texas MD Anderson Cancer Center has found that myelin is surprisingly dynamic, a discovery that has implications for treatment of multiple sclerosis and a type of myelin damage caused by some chemotherapy drugs, often...

– University of Texas M. D. Anderson Cancer Center

Journal of Clinical Investigation

Embargo expired on 23-Mar-2020 at 16:00 ET

CAR Macrophages Go Beyond T Cells to Fight Solid Tumors

Penn Medicine research shows genetically engineering macrophages – an immune cell that eats invaders in the body – could be the key to unlocking cellular therapies that effectively target solid tumors

– Perelman School of Medicine at the University of Pennsylvania

Nature Biotechnology

Embargo expired on 23-Mar-2020 at 12:00 ET

JNCCN: How to Manage Cancer Care during COVID-19 Pandemic

Experts from Seattle Cancer Care Alliance share lessons learned from early experiences treating people with cancer during COVID-19 outbreak via free online article in JNCCN—Journal of the National Comprehensive Cancer Network

– National Comprehensive Cancer Network® (NCCN®)

Embargo expired on 18-Mar-2020 at 08:05 ET

Rutgers Cancer Institute of New Jersey Research Shows Autophagy Impacts Stress Response Pathways Promoting Survival in Laboratory Models

Research from investigators at Rutgers Cancer Institute of New Jersey shows that a cellular process known as autophagy promotes survival in mouse models by suppressing oxidative stress and a tumor suppressor known as p53.

– Rutgers Cancer Institute of New Jersey

Genes & Development, Mar-2020

Embargo expired on 18-Mar-2020 at 17:00 ET

OncoMX Knowledgebase Enables Research of Cancer Biomarkers and Related Evidence

Researchers at the George Washington University published a new knowledgebase and web portal, OncoMX, which will improve the exploration and research of cancer biomarkers in the context of related evidence.

– George Washington University

JCO Clinical Cancer Informatics, March-2020

April Edition of SLAS Discovery Now Accessible

April’s edition of SLAS Discovery features the cover article, “Maximizing the Value of Cancer Drug Screening in Multicellular Tumor Spheroid Cultures: A Case Study in Five Head and Neck Squamous Cell Carcinoma Cell Lines.”


SLAS Discovery

UCI team demonstrates ability to supercharge cells with mitochondrial transplantation

Irvine, Calif., March 23, 2020 – Researchers at the University of California, Irvine have shown that they can give cells a short-term boost of energy through mitochondrial transplantation. The team’s study, published today in the Journal of the A...

– University of California, Irvine

Journal of the American Heart Association, Mar-2020

Cancer Patients Over 65, on Multiple Medicines, Are at Higher Risk of Hospitalization

Older patients with prostate, breast, or lung cancer are more likely to be hospitalized after chemotherapy if they take more than five other medicines.

– Thomas Jefferson University

Journal of Geriatric Oncology

Immunotherapy using ‘young cells’ offers promising option against cancer

A new study from Washington University School of Medicine in St. Louis suggests that the age of certain immune cells used in immunotherapy plays a role in how effective it is. These cells — natural killer (NK) cells — appear to be more effective ...

– Washington University in St. Louis

Developmental Cell

E-cigarette users had substances linked to bladder cancer in urine

In the review published in the journal European Urology Oncology, researchers compiled the results of 22 different studies that analyzed the urine of people who used e-cigarettes or other tobacco products, including cigarettes, to check for evidence ...

– University of North Carolina Health Care System

European Urology Oncology, March-2020

Pembrolizumab shows promise for some advanced, hard-to-treat rare cancers

Pembrolizumab shows promise for some advanced, hard-to-treat rare cancers. Open-label Phase II study at MD Anderson reports on four cancer types.

– University of Texas M. D. Anderson Cancer Center

Journal for ImmunoTherapy of Cancer

Webinars with patients-survey: 73% with chronic illnesses feel more COVID-19 risk

As the global pandemic continues and its impact increasingly disrupts daily life in the U.S., a new ongoing survey launched this week reveals specific concerns about the novel coronavirus among people living with chronic illnesses, who feel these con...

– Health Perspectives Group

Cancer Experts and Features

Coming Home to Fight Cancer

For Erika Maestas, MD, the journey to UNM Cancer Center is a journey home. Maestas grew up in Albuquerque, while her parents hailed from rural northern New Mexico. She likes that the UNM Cancer Center’s cutting edge research into cancer treatments ...

– University of New Mexico Comprehensive Cancer Center

How Will COVID-19 Impact My Upcoming Surgery?

If you or a loved one just had a scheduled cardiac or thoracic operation postponed because of the coronavirus (COVID-19) pandemic, you are not alone.

– The Society of Thoracic Surgeons

COVID-19 recommendations for patients receiving anti-cancer immunotherapies

Could medicines that activate the immune system protect against COVID-19 infection?

– University of Colorado Cancer Center

AACI Urges Immediate Implementation of Defense Production Act

The Association of American Cancer Institutes calls for the immediate implementation of the Defense Production Act to marshal American manufacturing to confront the COVID-19 emergency.

– Association of American Cancer Institutes (AACI)

Cancer Researcher Offers Tips for How to Manage Stress During COVID-19 Pandemic

– Indiana University

Cancer Announcements

National Comprehensive Cancer Network Announces Addition of UCLA Jonsson Comprehensive Cancer Center and UT Southwestern Simmons Comprehensive Cancer Center

National Comprehensive Cancer Network (NCCN) announces addition of UCLA Jonsson Comprehensive Cancer Center and UT Southwestern Simmons Comprehensive Cancer Center to not-for-profit alliance of leading cancer centers responsible for creating and up...

– National Comprehensive Cancer Network® (NCCN®)

Embargo expired on 24-Mar-2020 at 08:35 ET

PECASE Honoree James Olzmann Investigates the Secrets of Lipid Droplets

Lipid droplets, membrane-bound packages of lipids, have been one of our cells’ least studied components. But recently, more scientists have begun probing the mysteries that surround them and finding fascinating results. James Olzmann, Ph.D., discus...

– NIH, National Institute of General Medical Sciences (NIGMS)






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