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Newswise Special Wire
Tuesday, March 31, 2020

Public edition |

Newswise Cancer Research Wire for 31-Mar-2020

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Cancer Research

Cancer treatment with immune checkpoint inhibitors may lead to thyroid dysfunction

Thyroid dysfunction following cancer treatment with new treatments called immune checkpoint inhibitors is more common than previously thought, according to research that was accepted for presentation at ENDO 2020, the Endocrine Society’s annual mee...

– Endocrine Society

Journal of the Endocrine Society, Apr/May-2020; ENDO 2020, Mar-2020

Embargo expired on 31-Mar-2020 at 12:00 ET

Survey finds physicians struggle to communicate positive prognosis to thyroid cancer patients

Despite excellent prognosis with most thyroid cancers, many newly diagnosed patients have cancer-related worry, and physicians vary in their responses to patients' worry, according to new research accepted for presentation at ENDO 2020, the Endocrine...

– Endocrine Society

Journal of the Endocrine Society, Apr/May-2020; ENDO 2020, Mar-2020

Embargo expired on 31-Mar-2020 at 12:00 ET

New therapeutic strategies proposed for some lung and kidney cancers

New therapeutic strategies proposed for some lung and kidney cancers. Study shows cancers with high levels of the SLC7A11 gene may respond to glucose transporter inhibitor treatment.

– University of Texas M. D. Anderson Cancer Center

Nature Cell Biology

Embargo expired on 30-Mar-2020 at 11:00 ET

New blood test can detect wide range of cancers, now available to at risk individuals in clinical study at Dana-Farber

In a study involving thousands of participants, a new blood test detected more than 50 types of cancer as well as their location within the body with a high degree of accuracy, according to an international team of researchers led by Dana-Farber Canc...

– Dana-Farber Cancer Institute

Annals of Oncology

Embargo expired on 30-Mar-2020 at 19:00 ET

The pros and cons of radiotherapy: will it work for you?

Women undergoing radiotherapy for many cancers are more likely than men to be cured, but the side effects are more brutal, according to one of Australia’s most experienced radiation oncology medical physicists.

– University of South Australia

Critical Reviews in Oncology/Hematology

Moffitt Researchers Identify Novel Therapeutic Targets in Cutaneous Squamous Cell Carcinoma

Researchers at Moffitt Cancer Center want to devise better therapeutic strategies for patients with cutaneous squamous cell carcinoma (cuSCC) by improving their understanding of how the disease develops. In a new article published online ahead of pri...

– Moffitt Cancer Center

Cancer Research, March-2020

Experiments in Mice And Human Cells Shed Light On Best Way to Deliver Nanoparticle Therapy For Cancer

Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors passively — allowing the nanoparticles to diffuse into tumors and become held in place, or activel...

– Johns Hopkins Medicine

Science Advances; 5R25GM109441, P30 CA006973

Androgen receptor stops tumor growth in the most common form of breast cancer

Researchers say they have found a viable new therapeutic strategy for estrogen receptor-positive (ER+) breast cancer, even cancers that are resistant to current standard of care treatments. Their new preclinical study was accepted for presentation at...

– Endocrine Society

Journal of the Endocrine Society, Apr/May-2020

How Should Radiation Oncologists Manage Prostate Cancer Patients During the COVID-19 Pandemic?

An international team issues recommendations for managing prostate cancer patients during the COVID-19 pandemic

– Michigan Medicine - University of Michigan

Advances in Radiation Oncology

Experimental medication to prevent heart disease may treat chemo-resistant ovarian cancer

University of Colorado Cancer Center group shows CPT1A may be necessary for ovarian cancer spread, chemo-resistance. Moves toward clinical trial of CPT1A inhibitor, etomoxir, against chemo-resistant ovarian cancer.

– University of Colorado Cancer Center

Molecular Cancer Research; American Cancer Society, 16-184-56; National Institutes of Health, R00CA194318; Department of Defense, OC170228; American Cancer Society, RSG-16-256-01-TBE...

When Prostate Cancer Recurs, Adding Hormone Therapy to Radiation May Harm Men with Low PSA Levels

A secondary analysis of the Radiation Therapy Oncology Group (RTOG) 9601 phase 3 randomized clinical trial finds the benefit of hormone therapy varies depending on a patient’s PSA level.

– Michigan Medicine - University of Michigan

JAMA Oncology

Moffitt Researchers Discover Novel Role of Specific Histone Deacetylase in Non-Small Cell Lung Cancer

Researchers at Moffitt Cancer Center are trying to identify alternative strategies to treat non-small cell lung cancer. (NSCLC) In a new article published online in Scientific Reports, they highlight how targeting the histone deacetylase HDAC11 may b...

– Moffitt Cancer Center

Scientific Reports, March-2020

Those Living in Rural Areas, Uninsured or on Medicaid Less Likely to Receive Recommended Lung Cancer Treatment

Keck Medicine of USC study reveals that non-small cell lung cancer patients with pathologic N1 disease were less likely to receive chemotherapy if they lived in rural areas or were on Medicaid or uninsured.

– Keck Medicine of USC

The Annals of Thoracic Surgery

Breast Cancer Screening Costs High, Benefits Uncertain, for Women in 40s

There are substantial costs associated with breast cancer screenings for U.S. women in their 40s, a new Yale Cancer Center-led study finds, and these costs vary widely by region.

– Yale Cancer Center

JAMA Internal Medicine

Combination creates powerful central memory T cells for cellular therapy

MD Anderson researchers find that treating T cells with panobinostat and IL-21 re-programs them to a powerful central memory T cell type that persists longer.

– University of Texas M. D. Anderson Cancer Center

Cancer Immunology Research

Study: Despite failures, chemo still promising against dangerous childhood brain cancer, DIPG

Chemotherapy has been so unsuccessful against DIPG that researchers have questioned whether chemotherapy drugs are even able to reach the cancer. University of Colorado Cancer Center study shows, "... medicine does reach DIPG tissue in good quantitie...

– University of Colorado Cancer Center

Neuro-Oncology Advances

Supercomputer Helps Benchmark Cancer Immunotherapy Tool

With an estimated 1.7 million new cases and 600,000 deaths during 2017 in the U.S. alone, cancer remains a critical healthcare challenge. Researchers used the Comet supercomputer at the San Diego Supercomputer Center (SDSC) to evaluate their new mole...

– University of California San Diego

BMC Molecular and Cell Biology, Sep-2019; 1R21CA209941-01

Cancer Experts and Features

How Errors in Divvying Up Chromosomes Lead to Defects in Cells

During the fundamental process of mitosis, a type of cell division, dividing cells sometimes make errors while divvying up chromosomes. Understanding how this happens may help researchers develop targeted therapies for a variety of diseases, includin...

Expert Available

– NIH, National Institute of General Medical Sciences (NIGMS)

DP2GM119177; R01GM134132; R01GM079373; P01GM105537; R35GM130365

Cancer Announcements

Phoenix Dermatologist & Oncologist Honored for Providing Collaborative Care to Patient with Rare Cancer

American Academy of Dermatology recognizes Drs. Lindsay Ackerman and Craig Reeder with national “Patient Care Hero” awards

– American Academy of Dermatology

Dr. Mehra Golshan Appointed Deputy Chief Medical Officer for Surgical Services at Smilow Cancer Hospital and Yale Cancer Center

Mehra Golshan, M.D., M.B.A., F.A.C.S., has been appointed the inaugural Deputy Chief Medical Officer for Surgical Services at Smilow Cancer Hospital and Yale Cancer Center, Professor of Surgery at Yale School of Medicine, and Interim Director of the ...

– Yale Cancer Center





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