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Newswise Special Wire
Tuesday, April 7, 2020

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Newswise Cancer Research Wire for 07-Apr-2020

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Cancer Research

Pancreatic cancer blocked by disrupting cellular pH balance

Scientists at Sanford Burnham Prebys have found a new way to kill pancreatic cancer cells by disrupting their pH equilibrium. The study, published in Cancer Discovery, reports how depleting an ion transport protein lowers the pH to a point that compr...

– Sanford Burnham Prebys Medical Discovery Institute

W81XWH-17-10316; 15-20-25-COMM; R01DK099551; CA030199; T30FT0953; Cancer Discovery

Embargo expired on 07-Apr-2020 at 08:00 ET

Inherited mutation can predispose children to a type of brain tumor

Collaboration co-led by researchers at St. Jude Children’s Research Hospital discovers a novel predisposition gene in pediatric medulloblastoma.

– St. Jude Children's Research Hospital

Nature, Apr. 2020

Embargo expired on 01-Apr-2020 at 11:00 ET

NUS researchers uncover hereditary mutation that drives aggressive head and neck, and lung cancers in Asian population

New research from the Cancer Science Institute of Singapore at the National University of Singapore revealed a genetic variant in a gene called MET that is responsible for more aggressive growth of head and neck, and lung cancers in Asian populations...

– National University of Singapore

Nature Communications

Fiber consumption linked to lower breast cancer risk

Consuming a diet high in fiber was linked with a reduced incidence of breast cancer in an analysis of all relevant prospective studies. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society

– Wiley


To divide or not to divide? The mother cell may decide

Researchers at CU Boulder have found that it’s the mother cell that determines if its daughter cells will divide. The finding, explained in a new study out today in Science, sheds new light on the cell cycle using modern imaging technologies, and c...

– University of Colorado Boulder


Hybrid microscope creates digital biopsies

Bioengineers have combined standard microscopy, infrared light, and artificial intelligence to assemble digital biopsies that identify important molecular characteristics of cancer biopsy samples.

– National Institute of Biomedical Imaging and Bioengineering

PNAS, Feb-2020; R01EB009745

A direct protein-to-protein binding couples cell survival to cell proliferation

The regulators of apoptosis watch over cell replication and the decision to enter the cell cycle. Researchers now show a direct link between the protein MCL1 — a member of the BCL2 protein family known as the gatekeepers of apoptosis — and the ce...

– University of Alabama at Birmingham

GM117391 ; NS048039; Cell Death & Disease

Roswell Park Reports Extended Survival Among Breast Cancer Survivors Who Exercise Regularly

New research from Roswell Park Comprehensive Cancer Center, published in the Journal of the National Cancer Institute, shows that following those guidelines can improve clinical outcomes for patients with high-risk breast cancer, or breast cancer tha...

– Roswell Park Comprehensive Cancer Center

Journal of the National Cancer Institute; R01CA116395; R01CA139426; P30CA016056; UG1CA189974; CA180888; CA180819; CA180863; CA180858; CA180828...

Mechanical Engineers Develop Tumor Model that More Closely Mimics the Body

In research recently published in Acta Biomaterialia, a team of mechanical engineers at Rensselaer Polytechnic Institute demonstrated a new technique for creating an in vitro model for studying tumors that is more complex and, therefore, closer to wh...

– Rensselaer Polytechnic Institute (RPI)

Acta Biomaterialia

Colorado study overturns ‘snapshot’ model of cell cycle in use since 1974

Live, single-cell imaging shows that cells continuously integrate the influence of growth factors, not just during G1 phase of cell cycle, as previously thought.

– University of Colorado Cancer Center


Genetics Researchers Find Easy Way to Improve Cancer Outcomes

By mining a vast trove of genetic data,researchers at the University of Virginia School of Medicine are enhancing doctors’ ability to treat cancer, predict patient outcomes and determine which treatments will work best for individual patients. The...

– University of Virginia Health System

Genome Medicine; R01 CA166054; R01 1094 CA60499; 32 GM007267; AHA 18PRE33990261

Significant global investment could save 11 million children

Spending $20 million per year for 30 years would yield a 3-to-1 productivity gain of almost $2 trillion to the global economy according to St. Jude Global director and Lancet Oncology Commission co-chair.

– St. Jude Children's Research Hospital


Targeting a transporter to treat SHH medulloblastoma

Scientists at St. Jude Children’s Research Hospital have identified a novel target for a type of pediatric brain tumor.

– St. Jude Children's Research Hospital

Cancer Research, Published Jan. 16, 2020

Tip Sheet: Tracking COVID-19, protein design, TB vaccines, a new brain map and more

Summaries of recent Fred Hutch research findings with links for additional background and media contacts.

– Fred Hutchinson Cancer Research Center

Increasing Muscle Size and Strength, Exergames and Older Adults and Treadmills and Cancer Care from Medicine & Science in Sports & Science

If you're looking for health and fitness story ideas, view these research highlights from ACSM’s flagship research journal Medicine & Science in Sports & Exercise®.

– American College of Sports Medicine (ACSM)

Cancer Experts and Features

Angiotensin Hormone’s Protective Effects Could Improve Cancer Treatment

– American Physiological Society (APS)

American Journal of Physiology- Heart and Circulatory Physiology

Rutgers Cancer Institute Offers Clinical Trial Examining Potential Treatment for COVID-19

Rutgers Cancer Institute of New Jersey, a National Cancer Institute-designated Comprehensive Cancer Center, is offering a clinical trial as a potential treatment for patients diagnosed with the coronavirus (COVID-19). The trial, which is not limited ...

– Rutgers Cancer Institute of New Jersey

New mental health challenges for cancer patients during COVID-19

Benjamin Brewer, PsyD, is a University of Colorado Cancer Center investigator and health psychologist at the UCHealth University of Colorado Hospital Bone Marrow Transplant Program. Here CU Cancer Center talks with Dr. Brewer about his patients’ ne...

Expert Available

– University of Colorado Cancer Center

CANCER AND COVID-19: Moffitt Cancer Center Experts & Resources

– Moffitt Cancer Center

Cancer Announcements

Alleviating Confusion around Pain Management Recommendations

New information from NCCN, ASCO, ASH, CDC, FDA, and others seeks to provide clear guidance on how to optimally manage cancer-related pain without exacerbating the ongoing opioid crisis—published jointly in the Journal of the National Comprehensive ...

– National Comprehensive Cancer Network® (NCCN®)

JNCCN—Journal of the National Comprehensive Cancer Network

Roswell Park’s Dr. Pawel Kalinski to Lead $14.5M NCI-Funded Immunotherapy Effort

A team led by Pawel Kalinski, MD, PhD, of Roswell Park Comprehensive Cancer Center has earned a five-year, $14.54 million award from the National Cancer Institute (NCI) to expand a promising immunotherapy platform. Funded through the NCI’s Program ...

– Roswell Park Comprehensive Cancer Center

Cancer Center Receives Additional $5 Million in Funding from State of Kansas to Support Ongoing Research

The University of Kansas Cancer Center will receive an additional $5 million from the state budget for the KU Cancer Center Research Fund.

– University of Kansas Cancer Center





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