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Newswise Special Wire
Tuesday, April 28, 2020

Public edition | newswise.com

Newswise Cancer Research Wire for 28-Apr-2020
 

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.


Cancer Research


Study finds no overall survival benefit, but improved quality of life with talazoparib in advanced BRCA-mutated breast cancer

New data from the Phase III EMBRACA trial led by researchers at The University of Texas MD Anderson Cancer Center found the PARP inhibitor talazoparib did not demonstrate a statistically significant overall survival (OS) benefit for patients with met...

– University of Texas M. D. Anderson Cancer Center

New England Journal of Medicine

Embargo expired on 27-Apr-2020 at 00:05 ET


MD Anderson and Ipsen advance new therapy with potential benefit for underserved patients with lung and ovarian cancer

MD Anderson and Ipsen have advanced a new targeted therapy into clinical trials for certain patients with lung and ovarian cancers. Details are being presented at the AACR Annual Meeting.

– University of Texas M. D. Anderson Cancer Center

AACR Annual Meeting

Embargo expired on 27-Apr-2020 at 00:05 ET


Immune system changes occur early in development of multiple myeloma, study finds

Long before multiple myeloma becomes a malignant disease, the collection of immune system cells and signal carriers amid the tumor cells undergoes dramatic shifts, with alterations in both the number and type of immune cells, researchers at Dana-Farb...

– Dana-Farber Cancer Institute

Nature Cancer

Embargo expired on 27-Apr-2020 at 11:00 ET


Superior Progression-Free Survival Associated with Continuous Targeted Therapy Combination for BRAF-mutated Melanoma

Results from a randomized phase 2 clinical trial examining the targeted therapy drugs dabrafenib and tremetinib in both continuous and intermittent treatment of patients with BRAF-mutated melanoma show continuous dosing yields superior progression fr...

– Rutgers Cancer Institute of New Jersey

AACR Annual Meeting, Apr-2020

Embargo expired on 27-Apr-2020 at 00:05 ET


Study Shows Immunotherapy Prior to Surgery May Help Destroy High-Risk Breast Cancer

A new study led by Yale Cancer Center (YCC) researchers shows women with high-risk HER2-negative breast cancer treated before surgery with immunotherapy, plus a PARP inhibitor with chemotherapy, have a higher rate of complete eradication of cancer fr...

– Yale Cancer Center

AACR Annual Meeting, April 2020

Embargo expired on 27-Apr-2020 at 07:00 ET


New targeted agent produces considerable responses in trial with patients with uterine serous carcinoma

The DNA repair-blocking drug adavosertib shrinks tumors in nearly one-third of patients in clinical trial. Data will be shared virtually at the Society for Gynecologic Oncology (SGO) Annual Meeting on Women’s Cancer.

– Dana-Farber Cancer Institute

Society for Gynecologic Oncology (SGO) Annual Meeting

Embargo expired on 23-Apr-2020 at 20:00 ET


Hazardous Drug Spills Put Cancer Nurses at Risk

While lifesaving to cancer patients, chemotherapy drugs can be hazardous for the health care workers who handle them, especially during a spill. Inconsistent use of personal protective equipment when cleaning up a spill and problems with closed-sy...

– Michigan Medicine - University of Michigan

Clinical Journal of Oncology Nursing


Insights into Why Loud Noise is Bad for Your Health

Two new mouse studies provide new insight into how noise exposure can lead to high blood pressure and cancer-related DNA damage.

– Federation of American Societies for Experimental Biology (FASEB)

Experimental Biology 2020


CBD Shows Promise for Fighting Aggressive Brain Cancer

Findings from a new study examining human and canine brain cancer cells suggest that cannabidiol could be a useful therapy for a difficult-to-treat brain cancer. Cannabidiol, or CBD, is a non-psychoactive chemical compound derived from marijuana.

– Federation of American Societies for Experimental Biology (FASEB)

Experimental Biology 2020


Blood Test Offers Early Warning of Chemotherapy-Related Heart Problems

Scientists have identified a collection of biomarkers that together signal that a person’s cancer treatment may be harming their heart.

– Federation of American Societies for Experimental Biology (FASEB)

Experimental Biology 2020


Immunotherapy Before Surgery Could Advance Care of an Aggressive Form of Skin Cancer

In what is believed to be a first-of-its-kind study to evaluate the safety of a type of immunotherapy before surgery in patients with an aggressive form of skin cancer, researchers report that the treatment eliminated pathologic evidence of cancer in...

– Johns Hopkins Medicine

Journal of Clinical Oncology; R01 CA142779


Medicaid expansion led to more insurance coverage and a higher rate of mammograms in seven states

In states that chose to expand Medicaid under the Affordable Care Act (ACA), lower-income women now have access to mammograms at a higher rate than in states that did not expand Medicaid coverage.

– American College of Surgeons (ACS)

Journal of the American College of Surgeons


Game theory suggests more efficient cancer therapy

Cornell mathematicians are using game theory to model how this competition could be leveraged, so cancer treatment – which also takes a toll on the patient’s body – might be administered more sparingly, with maximized effect.

– Cornell University

Proceedings of the Royal Society B: Biological Sciences


Boosting the immune system's appetite for cancer

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission.

– UT Southwestern Medical Center

Nature Communications


Uptake of Lung Cancer Screening May Depend on Making Testing Fast and Convenient

Value in Health announced today the publication of new research showing that uptake of lung cancer screening may depend on making testing fast and convenient.

– ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health, Apr-2020


Series of Rare Right-Colon Twists Highlights Need for Doctor Vigilance with New, Targeted Anti-Cancer Drugs

Study: with smaller clinical trials, it may be up to doctors to notice rare drug side effects

– University of Colorado Cancer Center

Frontiers in Oncology; University of Colorado Lung Cancer Specialized Program of Research Excellence P50CA058187; University of Colorado Cancer Center Thoracic Oncology Research Initiative...


Helping the heart heal itself

UT Southwestern Medical Center scientists have discovered a protein that works with others during development to put the brakes on cell division in the heart, they report today in Nature.

– UT Southwestern Medical Center

Nature


New heart attack testing protocol expedites treatment in ER

A new protocol using highly sensitive blood tests to determine whether someone is having a heart attack

– UT Southwestern Medical Center

JAMA Open


How cancer cells don their invisibility cloaks

Immunotherapy drugs that target a protein called programmed death ligand 1 (PD-L1) on the surface of cancer cells have quickly become a mainstay to treat many forms of cancer, often with dramatic results.

– UT Southwestern Medical Center

Nature Cancer


AI may help brain cancer patients avoid biopsy

Brain cancer patients in the coming years may not need to go under the knife to help doctors determine the best treatment for their tumors.

– UT Southwestern Medical Center

Neuro-Oncology


Research News Tip Sheet: Story Ideas From Johns Hopkins

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas ...

– Johns Hopkins Medicine

Circulation; Obstetrics and Gynecology; Patient Education and Counseling; npg Breast Cancer


New American Academy of Dermatology Survey Finds Most Americans Know Sun Protection Is Important, Yet Many Aren’t Protecting Themselves

As more Americans head outdoors for warmer weather and fresh air amid “shelter-in-place” measures, dermatologists from the American Academy of Dermatology have an important reminder: practice safe sun. Skin cancer is one of the most preventable t...

– American Academy of Dermatology


Cancer Experts and Features


American Academy of Dermatology Statement on the Dangers of Ultraviolet Exposure

There is no evidence to support the recent speculation that traditional ultraviolet exposure is an effective treatment for COVID-19. This misinformation may encourage the public to seek UV radiation from the sun and tanning beds, inherently increasin...

– American Academy of Dermatology


GW Dermatology Experts Available to Speak During Skin Cancer Awareness Month

– George Washington University


Cancer Announcements


Ronald Chen elected as Fellow to American Society of Clinical Oncology

Ronald Chen, MD, MPH, has been named a Fellow of the American Society of Clinical Oncology (FASCO) in honor of his extraordinary volunteer service, dedication and commitment to ASCO.

– University of Kansas Cancer Center


ASCO Award Recognizes Outstanding Contributions of Dr. Andrew Chapman in the Field of Geriatric Oncology

Chapman established one of the first multidisciplinary centers in the country specializing in treatment of senior adults with cancer

– Thomas Jefferson University


Researchers receive $2.8 million grant to develop blood-based test for liver transplant candidate selection

Researchers from the UCLA Jonsson Comprehensive Cancer Center received a $2.8 million, five-year grant from the National Cancer Institute to help develop a blood-based test to improve the selection and prioritization for patients with liver cancer wh...

– University of California, Los Angeles (UCLA), Health Sciences


Dana-Farber Cancer Institute faculty recognized as 2020 ASCO leaders in cancer research and care

The American Society of Clinical Oncology (ASCO) recognized four Dana-Farber Cancer Institute researchers as winners of ASCO's Special Awards, the Society’s highest honors. The recipients of these awards have worked to transform cancer care around...

– Dana-Farber Cancer Institute

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