Newswise — Rockville, Md. -- The journal Investigative Ophthalmology & Visual Science (IOVS) is commemorating the 25th anniversary of the development of optical coherence tomography (OCT) with the release of a special issue of more than 70 papers from authors on five continents.

“It is now evident that OCT has transformed the practice of retina and glaucoma clinicians,” said guest editor David Huang, MD, PhD, of Oregon Health and Science University (OHSU). “This is also a time when two new exciting trends in OCT have taken off: OCT angiography and intraoperative OCT.”

“At this quarter century mark, it is appropriate to take stock of this burgeoning technology,” said guest editor James Fujimoto, PhD, at the Massachusetts Institute of Technology (MIT).

The special issue covers a wide range of topics, including OCT technology and methods, cornea/anterior, retina, age-related macular degeneration, diabetic retinopathy and glaucoma – making the issue of interest to basic researchers and clinicians alike.

Anchoring the issue are seven invited review articles from pioneering research groups in their respective fields:

“The development, commercialization and impact of Optical Coherence Tomography,” by researchers in the lab of James Fujimoto, PhD, MIT

“Key developments for partial coherence biometry and optical coherence tomography in the human eye made in Vienna,” by researchers in the labs of Adolf F. Fercher, PhD, Christoph K. Hitzenberger, PhD, and Wolfgang Drexler, PhD, of the Medical University of Vienna, Austria

“Clinical Utility of OCT in Glaucoma,” by researchers in the lab of Joel Schuman, MD, of New York University

“Optical Coherence Tomography and the Development of Anti-Angiogenic Therapies in Neovascular Age-related Macular Degeneration,” by Philip J Rosenfeld, MD, PhD, at the University of Miami

“Optical Coherence Tomography Angiography,” by researchers in the lab of David Huang, MD, PhD, OHSU

“Optical coherence tomography for retinal surgery: perioperative analysis to real-time four-dimensional image-guided surgery,” by researchers in the labs of Joseph Izatt, PhD, and Cynthia Toth, MD, at Duke University

“A review of adaptive optics optical coherence tomography: technical advances, scientific applications, and the future,” by researchers in the labs of Donald Miller, PhD, of Indiana University, and John Werner, PhD, of the University of California, Davis


The ARVO peer-reviewed open access journal Investigative Ophthalmology & Visual Science (IOVS) publishes results from original hypothesis-based clinical and laboratory research studies, as well as Reviews, Perspectives and Special Issues. IOVS ranks No. 1 among 58 ophthalmology journals for number of citations and its 2015 Impact Factor places it at No. 6. The journal is online-only ( and articles are published daily. ARVO, an organization of nearly 12,000 researchers from over 75 countries, advances research worldwide into understanding the visual system and preventing, treating and curing its disorders. In addition to IOVS, ARVO publishes the Journal of Vision and Translational Vision Science & Technology.