Acid-sensing Ion Channels Are Required for Exercise-induced Muscle Pain

Newswise — Article title: ASICs are required for immediate exercise-induced muscle pain and are downregulated in sensory neurons by exercise training

Authors: Tahsin Khataei, Anne Marie S. Harding, Mahyar Janahmadi, Maram El-Geneidy, Hamid Agha-Alinejad, Hamid Rajabi, Peter M. Snyder, Kathleen A. Sluka, Christopher J. Benson

From the authors: “We found that acid-sensing ion channels (ASICs) are required for immediate exercise-induced muscle pain (IEIP). Moreover, exercise training prevented IEIP and was correlated with downregulation of ASICs in sensory neurons.” 

This study is highlighted as one of August’s "best of the best" as part of the American Physiological Society's APSselect program.