Feature Channels: AIDS and HIV

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Newswise: Common HIV drugs increase a type of immunity in the gut
Released: 22-Sep-2020 4:05 PM EDT
Common HIV drugs increase a type of immunity in the gut
University of Washington School of Medicine and UW Medicine

In this research, the investigators studied the effect of TDF/FTC in patients who were using the drug to prevent HIV, and in the absence of active HIV infection. The researchers observed patients over the past five years and also included data from two earlier studies.

Newswise: $111 Million NIH Grant Awarded to Prevent and Treat HIV-Associated Cancers
Released: 22-Sep-2020 11:00 AM EDT
$111 Million NIH Grant Awarded to Prevent and Treat HIV-Associated Cancers
Albert Einstein College of Medicine

The widespread use of antiretroviral therapy to suppress the HIV virus has helped tens of millions of people with HIV live healthier, longer lives—but an unfortunate consequence of people living longer with HIV is an increased risk of cancer. For 25 years, the AIDS Malignancy Consortium (AMC) has led national and international efforts to prevent and treat of HIV-related cancers. Now, Montefiore Health System and Albert Einstein College of Medicine have received a five-year, $111 million grant from the National Cancer Institute (NCI) to lead this research consortium.

Released: 17-Sep-2020 10:00 AM EDT
Medical mistrust grounded in structural and systemic racism affects HIV care for Black women in the US South
Wolters Kluwer Health: Lippincott

For Black women in the southern United States, mistrust of the health care system that is grounded in structural and systemic racism is a key factor affecting participation in HIV prevention and treatment services, reports a study in the September/October issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.

8-Sep-2020 3:00 PM EDT
State Laws Key to HIV Prevention Efforts
University of Pennsylvania School of Nursing

HIV prevention remains a public health priority in the United States. Pre-exposure prophylaxis (PrEP) is a drug regimen recommended for individuals who have engaged in behaviors that place them at elevated risk for HIV. When used consistently, daily oral PrEP has been shown to reduce HIV transmission by 99 percent. However, despite increases in PrEP awareness and uptake over the past several years, data show that four of five people who could benefit from PrEP did not access the medication in 2018.

Newswise: The BEAT-HIV Martin Delaney Collaboratory Issues 
Recommendations on Measuring Persistent HIV Reservoirs in Cure-directed Clinical Trials
7-Sep-2020 9:10 AM EDT
The BEAT-HIV Martin Delaney Collaboratory Issues Recommendations on Measuring Persistent HIV Reservoirs in Cure-directed Clinical Trials
Wistar Institute

Wistar scientists and top HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy (BEAT-HIV Collaboratory) compiled the first comprehensive set of recommendations on how to best measure the size of persistent HIV reservoirs during cure-directed clinical studies.

Newswise: Surgical Team Performs San Diego's First HIV Donor to HIV Recipient Liver Transplant
Released: 3-Sep-2020 1:35 PM EDT
Surgical Team Performs San Diego's First HIV Donor to HIV Recipient Liver Transplant
University of California San Diego Health

UC San Diego Health is the first hospital in San Diego and only health care system in Southern California to transplant a liver from a donor with Human Immunodeficiency Virus (HIV) into an HIV-positive recipient. The surgery is part of a national clinical trial.

Newswise: UTSW Performs First HIV-Positive-To-HIV-Positive Organ Transplant in Texas
Released: 2-Sep-2020 3:10 PM EDT
UTSW Performs First HIV-Positive-To-HIV-Positive Organ Transplant in Texas
UT Southwestern Medical Center

DALLAS, Sept. 2, 2020 – Less than three weeks after getting on an organ transplant list for HIV-positive patients, John Welch got the call. A liver was available from a deceased donor, and it was an excellent match.

Released: 31-Aug-2020 9:00 AM EDT
UM School of Medicine’s Institute of Human Virology Recruits Top HIV/AIDS Epidemiologist Shenghan Lai Along with Team of Researchers
Institute of Human Virology at the University of Maryland School of Medicine

IHV announced today that Shenghan Lai, MD, MPH and Hong Lai, PhD, MPH, in addition to three staff members, and two more to add, have joined the Institute of Human Virology. The faculty began their positions on April 1 with Professor and Associate Professor academic appointments in the UMSOM’s Department of Epidemiology & Public Health.

Newswise:Video Embedded beating-hiv-and-covid-19-may-depend-on-tweaking-vaccine-molecules
VIDEO
Released: 27-Aug-2020 3:45 PM EDT
Beating HIV and COVID-19 may depend on tweaking vaccine molecules
La Jolla Institute for Immunology

In a new Immunity study, researchers at La Jolla Institute for Immunology (LJI) show that one way to improve the body's immune response to vaccines is to factor in antigen valency. Valency refers to the number of antibody binding sites on an antigen.

Released: 21-Aug-2020 1:05 PM EDT
Long-acting, Injectable Drug Could Strengthen Efforts to Prevent, Treat HIV
University of Utah Health

Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects.

11-Aug-2020 8:00 AM EDT
American Chemical Society Fall 2020 Virtual Meeting Press Conference Schedule
American Chemical Society (ACS)

Watch live and recorded press conferences at https://www.acs.org/content/acs/en/pressroom/news-room/press-conferences.html. Press conferences will be held Monday, Aug. 17 through Thursday, Aug. 20, 2020

Newswise: Cryo-EM study yields new clues to chicken pox infection
Released: 18-Aug-2020 3:20 PM EDT
Cryo-EM study yields new clues to chicken pox infection
SLAC National Accelerator Laboratory

Stanford and SLAC scientists studying the varicella zoster virus found that an antibody that blocks infection doesn’t work exactly as they’d thought.

10-Aug-2020 3:25 PM EDT
MS Drug May be Used to Inhibit HIV Infection and Reduce Latent Reservoir
George Washington University

A multiple sclerosis drug may be used to block HIV infection and reduce the latent reservoir, according to research published in PLOS Pathogens by a team at the RGeorge Washington University.

Newswise: Penn State College of Medicine study explores the association of malaria, HIV with anemia during pregnancy
Released: 12-Aug-2020 3:50 PM EDT
Penn State College of Medicine study explores the association of malaria, HIV with anemia during pregnancy
Penn State College of Medicine

Pregnant women from sub-Saharan Africa with malaria and human immunodeficiency virus (HIV) have a higher prevalence of anemia than pregnant women without infections according to Penn State College of Medicine researchers. The findings may have implications for reducing the risk of death in pregnant women and preventing low birth weights and neurocognitive impairment in their children as a result of anemia.

Newswise: Short-Term Use of HIV-Prevention Medication Protects At-Risk Men on Vacation
Released: 12-Aug-2020 1:05 PM EDT
Short-Term Use of HIV-Prevention Medication Protects At-Risk Men on Vacation
Health Sciences at the University of Pittsburgh

Men at particular risk for HIV are very likely to consistently take prevention medication during vacations when their odds of contracting the virus are higher, according to a new study.

Released: 11-Aug-2020 6:50 PM EDT
Protein uses two antiviral strategies to ward off infections
eLife

To protect humans against infection, a protein called MARCH8 tags the vesicular stomatitis virus (VSV) for destruction while it merely holds HIV hostage, a new study in eLife shows.

Newswise: Coming of Age: Emerging Health Preference Research Based on Established Scientific Standards
Released: 10-Aug-2020 6:35 AM EDT
Coming of Age: Emerging Health Preference Research Based on Established Scientific Standards
ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health, the official journal of ISPOR, announced today the publication of a series of articles focused on recent developments in the field of health preference research.

Released: 7-Aug-2020 8:05 PM EDT
Penn Medicine-Led Research Suggests Greater Access to Specific HIV and Tuberculosis Medications is Needed Worldwide
Perelman School of Medicine at the University of Pennsylvania

A specific combination of HIV and TB treatments, difficult to obtain in certain parts of the world, decreased mortality risk for patients with HIV and multidrug-resistant TB

Newswise: New Sugar-based Signature Identifies T Cells Where HIV Hides and Persists Despite Antiretroviral Therapy
Released: 7-Aug-2020 10:30 AM EDT
New Sugar-based Signature Identifies T Cells Where HIV Hides and Persists Despite Antiretroviral Therapy
Wistar Institute

Wistar scientists may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

Released: 4-Aug-2020 11:55 AM EDT
ACTG Announces Launch of Novel Clinical Trial Testing Multiple Therapeutics to Treat COVID-19
University of California, Los Angeles (UCLA), Health Sciences

The AIDS Clinical Trials Group (ACTG) has initiated the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial. ACTIV-2 includes both phase 2 and phase 3 evaluations of multiple promising investigational agents for treating early COVID-19 in a single trial.

Newswise: Caught in the act – microscopy reveals key detail in retrovirus replication
Released: 29-Jul-2020 8:35 AM EDT
Caught in the act – microscopy reveals key detail in retrovirus replication
Penn State College of Medicine

A protein that is critical for retrovirus replication may select viral genetic material for packaging within the nuclei of host cells, rather than in the cytoplasm, as was previously believed.

Newswise: Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Released: 23-Jul-2020 11:00 AM EDT
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.

Newswise: Pioneering method reveals dynamic structure in HIV
Released: 16-Jul-2020 3:15 PM EDT
Pioneering method reveals dynamic structure in HIV
University of Utah

The method reveals that the lattice, which forms the major structural component of the human immunodeficiency virus (HIV), is dynamic. The discovery of a diffusing lattice made from Gag and GagPol proteins, long considered to be completely static, opens up potential new therapies. The method can be applied to biomedical structure.

Newswise: Faculty Receive Grant to Explore the Impact of COVID-19 on People Living with HIV
Released: 16-Jul-2020 1:25 PM EDT
Faculty Receive Grant to Explore the Impact of COVID-19 on People Living with HIV
Rutgers School of Public Health

Rutgers faculty receive grant to study how the current pandemic impacts people living with HIV, who may be at heightened risk for severe illness from COVID-19 compared to the general population.

Released: 16-Jul-2020 6:05 AM EDT
HIV Alone Not a Risk Factor for Cavities in Children
Rutgers University-New Brunswick

Recent studies indicate HIV infection heightens the risk of dental cavities – but a Rutgers researcher has found evidence that the risk of cavities comes not from HIV itself but from a weakened immune system, which could be caused by other diseases.

Released: 13-Jul-2020 9:05 PM EDT
Medicine and Education Lag in the Delivery of Services to Enhance Health of Sexually Active Adolescent Gay-Identified Men
Rutgers University-New Brunswick

Young gay sexual minority men – especially Black and Latino youth – have their first sexual experiences at younger ages, emphasizing a need for comprehensive and inclusive sex education, according to Rutgers researchers.

Released: 10-Jul-2020 1:00 PM EDT
Health, Bioethics Experts and Advocates Publish Guidance for Research on HIV, Co-infections in Pregnancy
University of North Carolina School of Medicine

The PHASES Working Group, co-led by researchers at UNC-Chapel Hill, Georgetown, and Johns Hopkins, launched ethics guidance at hivpregnancyethics.org, in a project dedicated to ending the evidence gap for pregnant women around HIV and co-infections.

8-Jul-2020 4:55 PM EDT
New $3.7M grant to support research exploring mysterious link between cancer, HIV/AIDS
Case Western Reserve University

Research has found that those living with HIV have a higher risk for certain kinds of cancers—such as lung cancer. Now, with a new five-year, $3.7 million grant from the National Cancer Institute, researchers from Case Western Reserve University hope to find out why.

Released: 8-Jul-2020 4:30 PM EDT
Nurses and Midwives Take the Lead in Providing HIV Services in Eastern and Southern Africa
Wolters Kluwer Health: Lippincott

“Nurse-initiated and managed antiretroviral therapy” (NIMART) is an innovative approach to making effective medications more accessible to people living with HIV (PLWH) in low-resource countries. A new study identifies challenges and opportunities to promoting nurse- and midwife-led HIV services in eastern and southern Africa, reports the July/August issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.

Released: 6-Jul-2020 1:45 PM EDT
UAlbany Establishes Center for HIV Research to Address Epidemic
University at Albany, State University of New York

The new Center for Collaborative HIV Research in Practice and Policy at the University at Albany will address the public health and social justice challenges of persons placed at risk for, or living with, HIV and related diseases.

Newswise: School HPV vaccine policies could result in higher vaccination rates, reduction in cancers
Released: 29-Jun-2020 7:35 PM EDT
School HPV vaccine policies could result in higher vaccination rates, reduction in cancers
University of California, Los Angeles (UCLA), Health Sciences

A UCLA-led study has found that in 2 of 3 states and jurisdictions with policies that require students entering school to receive the human papillomavirus vaccine, vaccination rates among 13-to-17-year-olds were significantly higher than in surrounding states without such policies.

Released: 29-Jun-2020 9:30 AM EDT
Mount Sinai Researchers Find That COVID-19 Patients with HIV Did Not Experience Poorer Outcomes
Mount Sinai Health System

Patients with HIV who were hospitalized with COVID-19 did not experience poorer outcomes compared to a similar comparison group of patients.

Newswise: AACN Honors ‘5B’ Nurses Who Transformed Care for Patients With AIDS
Released: 25-Jun-2020 11:50 AM EDT
AACN Honors ‘5B’ Nurses Who Transformed Care for Patients With AIDS
American Association of Critical-Care Nurses (AACN)

Nurses Alison Moëd and Cliff Morrison will receive AACN Pioneering Spirit Awards for their efforts to transform treatment for patients with AIDS in the early 1980s. Together, they created the San Francisco Model, a patient-centered approach that improved the care for their patients and countless others around the world.

19-Jun-2020 3:25 PM EDT
New drug candidate reawakens sleeping HIV in hopes of functional cure
Sanford Burnham Prebys Medical Discovery Institute

Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a next-generation drug called Ciapavir (SBI-0953294) that is effective at reactivating dormant human immunodeficiency virus (HIV). The research, published in Cell Reports Medicine, aims to create a functional HIV cure by activating and then eliminating all pockets of dormant HIV—an approach called “shock and kill.”

Released: 22-Jun-2020 5:50 PM EDT
ACTG Studies at AIDS 2020: Virtual
University of California, Los Angeles (UCLA), Health Sciences

Topics include the efficacy and safety of third-line treatment regimens in resource-limited settings, viral rebound rates after treatment interruption of modern ART, and whether a standardized frailty score can improve clinicians’ ability to estimate cardiovascular risk among older people with HIV.

Newswise: Satya Dandekar honored with prestigious NIH MERIT award for HIV research
Released: 22-Jun-2020 4:55 PM EDT
Satya Dandekar honored with prestigious NIH MERIT award for HIV research
UC Davis Health

Satya Dandekar, professor of microbiology and chairperson of the Department of Medical Microbiology and Immunology at UC Davis, honored by Prestigious NIH MERIT award for her illustrious journey in HIV research.

Newswise: UCLA receives nearly $14 million from NIH to investigate gene therapy to combat HIV
Released: 15-Jun-2020 5:10 PM EDT
UCLA receives nearly $14 million from NIH to investigate gene therapy to combat HIV
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers and colleagues have received a $13.65 million grant from the National Institutes of Health to investigate and further develop an immunotherapy known as CAR T, which uses genetically modified stem cells to target and destroy HIV.

Newswise: History of insightful HIV research inspires neutron scattering approach to studying COVID-19
Released: 12-Jun-2020 5:45 PM EDT
History of insightful HIV research inspires neutron scattering approach to studying COVID-19
Oak Ridge National Laboratory

What began as novel investigations into HIV, abruptly pivoted to the novel coronavirus as it began to spread across the globe. Now, ORNL researchers are using neutrons to learn more about the SARS-CoV-2 protease—a protein enzyme that enables the virus to replicate within the human body. Insights on the protein structure and its behaviors will be used to create more accurate models for simulations in aims of finding drug inhibitors to block the virus’s ability to reproduce.

Released: 1-Jun-2020 8:05 AM EDT
COVID-19 in People Living with HIV
Rutgers University-New Brunswick

Rutgers expert explains why COVID-19 pandemic poses additional difficulties, risks to people with HIV

Newswise:Video Embedded covid-19-a-wake-up-call-for-the-need-for-new-antiviral-weapons
VIDEO
Released: 26-May-2020 3:00 PM EDT
COVID-19: A wake-up call for the need for new antiviral weapons
Morgridge Institute for Research

Even after heroic medical and societal efforts finally break the back of the current COVID-19 pandemic, the global sigh of relief may not last long. The chilling reality is that viral threats are growing more common. And they’re getting deadlier.

19-May-2020 1:45 PM EDT
Combining Multiple Measures of Alcohol Use Helps Clarify Risky Drinking in People with HIV
Research Society on Alcoholism

Researchers and clinicians can better understand the health risks facing people with HIV through comprehensive measures of alcohol use, including objective biomarkers, according to a new study in Alcoholism: Clinical and Experimental Research. Frequent or heavy alcohol use in people with HIV can affect HIV disease progression and comorbidities. Alcohol use disorder is a barrier to effectively managing HIV and contributes in multiple ways to poor health outcomes. These effects are not well understood, however, owing in part to the limitations of self-report tools (questionnaires) for measuring alcohol use. Researchers at Louisiana State University and Tulane University correlated self-reported alcohol use, measured by multiple questionnaires, with a biomarker of alcohol consumption in people with HIV. This study explores the implications of this multi-faceted approach for understanding the alcohol use of people with HIV and the related risk factors.

Released: 7-May-2020 6:30 PM EDT
Dearth of Medical Resources in Africa for COVID-19 Reminiscent of Early HIV/AIDS Pandemic
Georgetown University Medical Center

Global health scholars have issued a clarion call about the needless loss of life expected because of a foreseeable prospect of “slow and inadequate access to supplies” to control COVID-19 in sub-Saharan Africa. They say what is unfolding now is similar to when lifesaving diagnostics and treatments came to the region long after they were available elsewhere.

Newswise: Research News Tip Sheet: Story Ideas From Johns Hopkins
Released: 30-Apr-2020 8:00 AM EDT
Research News Tip Sheet: Story Ideas From Johns Hopkins
Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.

Newswise: New University of Kentucky study could change what we know about platelets
Released: 29-Apr-2020 9:00 AM EDT
New University of Kentucky study could change what we know about platelets
University of Kentucky

The $6.6 million study will focus on how platelets function when they form clots in blood vessels and when they sense circulating pathogens, like viruses.

Newswise: Potential new HIV treatment could mean once-a-year injection
AUDIO
Released: 27-Apr-2020 12:55 PM EDT
Potential new HIV treatment could mean once-a-year injection
University of Nebraska Medical Center (UNMC)

The advance has the potential to eliminate complications that arise from missing doses of life-saving medicines, according to the study published today in Nature Materials, a leading peer-reviewed biomedical research journal.

Released: 20-Apr-2020 3:45 PM EDT
Africa in the path of COVID-19
Columbia University, Mailman School of Public Health

In a New England Journal of Medicine "Perspective" published today, Wafaa El-Sadr, MD, MPH, global director of ICAP at Columbia University Mailman School of Public Health, and Jessica Justman, MD, ICAP's senior technical director, and associate professor of epidemiology, urge a coordinated global effort in the face of the COVID-19 pandemic, with "countries around the world [taking] concrete steps to assist Africa in staying ahead of the curve, even as they confront their own epidemics."

Released: 7-Apr-2020 9:50 AM EDT
Depressive Disorders Are ‘Under Recognized and Under Treated’ in People with HIV/AIDS
Wolters Kluwer Health: Lippincott

People living with HIV/AIDS are at increased risk of depressive disorders. But all too often, these conditions go unrecognized or untreated, suggests a literature review in the May/June issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.


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