Feature Channels: AIDS and HIV

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Released: 15-Dec-2020 10:10 AM EST
University of Maryland School of Medicine Institute of Human Virology’s Shyam Kottilil, MBBS, PhD Receives Top Award from National Physician’s Group
Institute of Human Virology at the University of Maryland School of Medicine

Shyam Kottilil, MBBS, PhD, professor of medicine at the University of Maryland School of Medicine (UMSOM), and Director of UMSOM’s Institute of Human Virology (IHV) Division of Clinical Care and Research, has been awarded Mastership in the American College of Physicians (ACP), the national organization of internists.

Released: 11-Dec-2020 11:00 AM EST
Scientists at Texas Biomed aim to test therapeutic effects of CBD/THC against HIV-induced neurological disorder
Texas Biomedical Research Institute

The National Institutes of Health (NIH) awarded Professor Mahesh Mohan, D.V.M., Ph.D., and collaborators more than $3.5 million over five years to investigate the effects of cannabinoids on Human Immunodeficiency Virus (HIV) associated neurocognitive disorder (HAND). This research project aims to evaluate whether delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) alone or in combination can potentially alter DNA methylation, which is a biological process that can create a change in the expression of certain genes.

Newswise: Research News Tip Sheet: Story Ideas From Johns Hopkins Medicine
Released: 8-Dec-2020 11:00 AM EST
Research News Tip Sheet: Story Ideas From Johns Hopkins Medicine
Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.

Released: 2-Dec-2020 3:50 PM EST
Tip Sheet: Celebrate holidays safely, COVID-19 vaccines, challenges in HIV vaccine trials — and new insights on evolution
Fred Hutchinson Cancer Research Center

SEATTLE – Dec. 2, 2020 – Below are summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.If you’re following the American Society of Hematology’s annual meeting (virtual, Dec. 5-8), see our media tip sheet highlighting Fred Hutch presentations and activities, including those by current ASH president Dr.

Newswise: To Meet HIV World Health Goals, TB Treatment Must be Maintained During COVID-19 Response
Released: 1-Dec-2020 12:55 PM EST
To Meet HIV World Health Goals, TB Treatment Must be Maintained During COVID-19 Response
American Thoracic Society (ATS)

This World AIDS Day, the Forum of International Respiratory Societies (FIRS), of which the ATS is a founding member, is calling on governments, health advocates and non-government organizations to strengthen their response to AIDS and tuberculosis, and to ensure that TB services are maintained throughout their response to COVID-19.

Released: 30-Nov-2020 1:45 PM EST
UC San Diego Selected to Lead International HIV/AIDS Clinical Trials Unit
University of California San Diego Health

University of California San Diego has been selected by the NIH to lead and administer an international seven-year, $28-million grant for HIV/AIDS clinical trials.

Released: 30-Nov-2020 1:35 PM EST
NIH Re-Funds ACTG for the Next Seven Years
University of California, Los Angeles (UCLA), Health Sciences

The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, has been re-funded for the next seven years by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and collaborating NIH Institutes.

Newswise: Arnhold Institute for Global Health to Host Mount Sinai World AIDS Day
Released: 24-Nov-2020 9:00 AM EST
Arnhold Institute for Global Health to Host Mount Sinai World AIDS Day
Mount Sinai Health System

The Arnhold Institute for Global Health at the Icahn School of Medicine Mount Sinai will host a virtual event on World AIDS Day.

Newswise: 249281_web.jpg
Released: 23-Nov-2020 12:50 PM EST
Growing risks of STIs in over-45s
University of Chichester

OVER-45s are at a higher risk of contracting STIs than ever before because of society's unwillingness to talk about middle-aged and older people having sex, a new report has found.

16-Nov-2020 2:45 PM EST
January 2021 highlights from AJPH
American Public Health Association (APHA)

Highlights from January 2021 issue of AJPH. Better use of HIV prevention funds could substantially cut new infections; Study explores link between natural disasters, onset of headaches, digestive and back problems; Backpack medicine a promising way to reach people who are homeless during COVID-19; Successful contact tracing programs require a sustainable workforce

Newswise: Faculty Receives Grant to Examine the Effect of HIV on Children’s Epigenetic Patterns
Released: 18-Nov-2020 2:30 PM EST
Faculty Receives Grant to Examine the Effect of HIV on Children’s Epigenetic Patterns
Rutgers School of Public Health

Rutgers School of Public Health instructor, Stephanie Shiau, has been awarded a Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health R21 grant to examine the effect of HIV infection and/or exposure during pregnancy on epigenetic patterns in children.

16-Nov-2020 12:00 PM EST
ACTG Presents Data Showing Minimal Monitoring Approach to Hepatitis C Treatment is Safe and Successful at AASLD’s 2020 Liver Meeting
University of California, Los Angeles (UCLA), Health Sciences

Study finds that in a diverse, global patient population, a minimal monitoring (MINMON) approach to hepatitis C treatment was safe and achieved comparable sustained virologic response (SVR) to current standard of care.

Newswise: Albert Einstein College of Medicine Researchers Receive $5 Million NIH Grant to Study HIV and HPV Cancers in Africa
Released: 13-Nov-2020 11:55 AM EST
Albert Einstein College of Medicine Researchers Receive $5 Million NIH Grant to Study HIV and HPV Cancers in Africa
Albert Einstein College of Medicine

A team of scientists from Albert Einstein College of Medicine has received a five-year, $4.9 million grant from the National Institutes of Health (NIH) to establish a research center to investigate HIV- and human papillomavirus (HPV)-related cancers in Africa.

Released: 12-Nov-2020 9:00 AM EST
Leading Human Immunology and Infectious Disease Experts to Join UM School of Medicine’s Institute of Human Virology
Institute of Human Virology at the University of Maryland School of Medicine

Robert C. Gallo, MD, the Homer & Martha Gudelsky Distinguished Professor in Medicine at the University of Maryland School of Medicine (UMSOM) and Co-Founder & Director of the UMSOM’s Institute of Human Virology (IHV), announced today that a team of leading scientists in human immunology, virology and stem cell biology, led by Lishan Su, PhD joined IHV on October 1 with academic appointments in the UMSOM Department of Pharmacology. As part of the Maryland E-Nnovation Initiative Fund (MEIF) to recruit top research faculty and a donation to IHV from the Charles Gordon Estate, Dr. Su has been named the Charles Gordon Smith Endowed Professor for HIV Research. Dr. Su will also head IHV’s Division of Virology, Pathogenesis and Cancer.

6-Nov-2020 7:00 AM EST
Alcohol Use Increases among People Living with HIV during Stay-at-home Order
American Physiological Society (APS)

Researchers at Louisiana State University Health Sciences Center in New Orleans honed in on one population particularly at risk during the pandemic: people living with HIV with at-risk alcohol use. They surveyed 80 people living with HIV in Louisiana during that state’s stay-at-home order, recruiting participants from the ongoing longitudinal Aging in Louisiana: Immunosenescence, HIV and Socioenvironmental Factors-Exercise (ALIVE-Ex) study.

Newswise: Dean to Receive Hyacinth Award for HIV Work to End HIV/AIDS Epidemic
Released: 22-Oct-2020 11:40 AM EDT
Dean to Receive Hyacinth Award for HIV Work to End HIV/AIDS Epidemic
Rutgers School of Public Health

Rutgers School of Public Health dean, Perry N. Halkitis, will receive the Hyacinth Award, from the Hyacinth Foundation.

20-Oct-2020 6:05 PM EDT
Antiretroviral therapy can’t completely stop accelerated cell aging seen in HIV
University of California, Los Angeles (UCLA), Health Sciences

Untreated HIV infection is linked with epigenetic changes suggesting rapid aging. A new study by UCLA researchers shows that antiretroviral therapy given over two years was unable to completely restore age-appropriate epigenetic patterns, leaving patients more susceptible to aging-related illnesses.

Released: 19-Oct-2020 9:00 AM EDT
Unique program aims to educate Muslim teens on HIV prevention
Wolters Kluwer Health: Lippincott

Cultural taboos may leave Muslim American adolescents uninformed about romantic relationships and sex, placing them at risk of HIV and other sexually transmitted infections (STIs). A sex education program designed specifically for Muslim teens – with a foundation in Islamic morals and values – is reported in the November/December issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.

Released: 15-Oct-2020 11:20 AM EDT
Johns Hopkins Bloomberg School of Public Health Appoints David Celentano as New Bloomberg Centennial Professor
Johns Hopkins Bloomberg School of Public Health

Johns Hopkins Bloomberg School of Public Health has appointed David Celentano, ScD, MHS, as a Bloomberg Centennial Professor.

Released: 9-Oct-2020 10:05 AM EDT
CWRU and UH Researchers Secure $4 Million in NCI Funding to Investigate Relationships between HIV and Lung Cancer in East Africa
Case Western Reserve University

Researchers with the Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have secured $4 million in funding from the National Institutes of Health (NIH)/National Cancer Institute (NCI) to establish an HIV-associated Malignancy Research Center focused on lung cancer in East Africa.

Newswise: HIV Up Close: Unprecedented View of Virus Reveals Essential Steps for Causing AIDS
4-Oct-2020 8:00 PM EDT
HIV Up Close: Unprecedented View of Virus Reveals Essential Steps for Causing AIDS
University of Utah Health

Accomplishing a feat that had been a pipe dream for decades, scientists at University of Utah Health and University of Virginia have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome). Doing so has provided up-close access to the virus—which is otherwise obstructed from view deep within the cell—and enabled identification of essential components that HIV needs to replicate within its human host. The research publishes in the journal, Cell.

Newswise: ‘Repliclones’ Fuel Perplexing Persistence of HIV in the Blood of Some Patients on Medication
1-Oct-2020 10:45 AM EDT
‘Repliclones’ Fuel Perplexing Persistence of HIV in the Blood of Some Patients on Medication
Health Sciences at the University of Pittsburgh

In a new study, infectious disease researchers show that HIV viremia isn’t always nonadherence to medication or resistance to the drugs. Instead, the patients are victims of what the scientists have dubbed “repliclones” – large clones of HIV-infected cells that produce infectious virus particles.

Newswise: IL-21 protein a key part of immune response to central nervous system infections
Released: 5-Oct-2020 2:10 PM EDT
IL-21 protein a key part of immune response to central nervous system infections
Penn State College of Medicine

Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system.

Released: 2-Oct-2020 2:35 PM EDT
Chicago Center for HIV Elimination awarded $5 million for community COVID-19 testing and prevention
University of Chicago Medical Center

The Chicago Center for HIV Elimination, housed at the University of Chicago, has been awarded $5 million over two years through the National Institute of Health’s (NIH) RADx Underserved Populations program to support a COVID-19 testing project to engage two disenfranchised populations.

Newswise: Study Explores Link Between Methamphetamine Use And Risky Sexual Behavior
Released: 30-Sep-2020 9:00 AM EDT
Study Explores Link Between Methamphetamine Use And Risky Sexual Behavior
Johns Hopkins Medicine

Recreational use of the illicit drug methamphetamine has long been associated with increases in overall impatient and risky behavior. Now, a new study by Johns Hopkins Medicine researchers affirms that meth use increases not only sexual desire but also, specifically and measurably, the risk of casual sex without a condom for those who have an increase in sexual desire.

Newswise: HIV Drugs Could Prevent Diabetes, Study Suggests
Released: 23-Sep-2020 10:30 AM EDT
HIV Drugs Could Prevent Diabetes, Study Suggests
University of Virginia Health System

Patients taking drugs called NRTIs to treat HIV and hepatitis B had a 33% lower risk of developing diabetes.

Newswise: Common HIV drugs increase a type of immunity in the gut
Released: 22-Sep-2020 4:05 PM EDT
Common HIV drugs increase a type of immunity in the gut
University of Washington School of Medicine and UW Medicine

In this research, the investigators studied the effect of TDF/FTC in patients who were using the drug to prevent HIV, and in the absence of active HIV infection. The researchers observed patients over the past five years and also included data from two earlier studies.

Newswise: $111 Million NIH Grant Awarded to Prevent and Treat HIV-Associated Cancers
Released: 22-Sep-2020 11:00 AM EDT
$111 Million NIH Grant Awarded to Prevent and Treat HIV-Associated Cancers
Albert Einstein College of Medicine

The widespread use of antiretroviral therapy to suppress the HIV virus has helped tens of millions of people with HIV live healthier, longer lives—but an unfortunate consequence of people living longer with HIV is an increased risk of cancer. For 25 years, the AIDS Malignancy Consortium (AMC) has led national and international efforts to prevent and treat of HIV-related cancers. Now, Montefiore Health System and Albert Einstein College of Medicine have received a five-year, $111 million grant from the National Cancer Institute (NCI) to lead this research consortium.

Released: 17-Sep-2020 10:00 AM EDT
Medical mistrust grounded in structural and systemic racism affects HIV care for Black women in the US South
Wolters Kluwer Health: Lippincott

For Black women in the southern United States, mistrust of the health care system that is grounded in structural and systemic racism is a key factor affecting participation in HIV prevention and treatment services, reports a study in the September/October issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.

8-Sep-2020 3:00 PM EDT
State Laws Key to HIV Prevention Efforts
University of Pennsylvania School of Nursing

HIV prevention remains a public health priority in the United States. Pre-exposure prophylaxis (PrEP) is a drug regimen recommended for individuals who have engaged in behaviors that place them at elevated risk for HIV. When used consistently, daily oral PrEP has been shown to reduce HIV transmission by 99 percent. However, despite increases in PrEP awareness and uptake over the past several years, data show that four of five people who could benefit from PrEP did not access the medication in 2018.

Newswise: The BEAT-HIV Martin Delaney Collaboratory Issues 
Recommendations on Measuring Persistent HIV Reservoirs in Cure-directed Clinical Trials
7-Sep-2020 9:10 AM EDT
The BEAT-HIV Martin Delaney Collaboratory Issues Recommendations on Measuring Persistent HIV Reservoirs in Cure-directed Clinical Trials
Wistar Institute

Wistar scientists and top HIV researchers from the BEAT-HIV Martin Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy (BEAT-HIV Collaboratory) compiled the first comprehensive set of recommendations on how to best measure the size of persistent HIV reservoirs during cure-directed clinical studies.

Newswise: Surgical Team Performs San Diego's First HIV Donor to HIV Recipient Liver Transplant
Released: 3-Sep-2020 1:35 PM EDT
Surgical Team Performs San Diego's First HIV Donor to HIV Recipient Liver Transplant
University of California San Diego Health

UC San Diego Health is the first hospital in San Diego and only health care system in Southern California to transplant a liver from a donor with Human Immunodeficiency Virus (HIV) into an HIV-positive recipient. The surgery is part of a national clinical trial.

Newswise: UTSW Performs First HIV-Positive-To-HIV-Positive Organ Transplant in Texas
Released: 2-Sep-2020 3:10 PM EDT
UTSW Performs First HIV-Positive-To-HIV-Positive Organ Transplant in Texas
UT Southwestern Medical Center

DALLAS, Sept. 2, 2020 – Less than three weeks after getting on an organ transplant list for HIV-positive patients, John Welch got the call. A liver was available from a deceased donor, and it was an excellent match.

Released: 31-Aug-2020 9:00 AM EDT
UM School of Medicine’s Institute of Human Virology Recruits Top HIV/AIDS Epidemiologist Shenghan Lai Along with Team of Researchers
Institute of Human Virology at the University of Maryland School of Medicine

IHV announced today that Shenghan Lai, MD, MPH and Hong Lai, PhD, MPH, in addition to three staff members, and two more to add, have joined the Institute of Human Virology. The faculty began their positions on April 1 with Professor and Associate Professor academic appointments in the UMSOM’s Department of Epidemiology & Public Health.

Newswise:Video Embedded beating-hiv-and-covid-19-may-depend-on-tweaking-vaccine-molecules
VIDEO
Released: 27-Aug-2020 3:45 PM EDT
Beating HIV and COVID-19 may depend on tweaking vaccine molecules
La Jolla Institute for Immunology

In a new Immunity study, researchers at La Jolla Institute for Immunology (LJI) show that one way to improve the body's immune response to vaccines is to factor in antigen valency. Valency refers to the number of antibody binding sites on an antigen.

Released: 21-Aug-2020 1:05 PM EDT
Long-acting, Injectable Drug Could Strengthen Efforts to Prevent, Treat HIV
University of Utah Health

Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects.

11-Aug-2020 8:00 AM EDT
American Chemical Society Fall 2020 Virtual Meeting Press Conference Schedule
American Chemical Society (ACS)

Watch live and recorded press conferences at https://www.acs.org/content/acs/en/pressroom/news-room/press-conferences.html. Press conferences will be held Monday, Aug. 17 through Thursday, Aug. 20, 2020

Newswise: Cryo-EM study yields new clues to chicken pox infection
Released: 18-Aug-2020 3:20 PM EDT
Cryo-EM study yields new clues to chicken pox infection
SLAC National Accelerator Laboratory

Stanford and SLAC scientists studying the varicella zoster virus found that an antibody that blocks infection doesn’t work exactly as they’d thought.

10-Aug-2020 3:25 PM EDT
MS Drug May be Used to Inhibit HIV Infection and Reduce Latent Reservoir
George Washington University

A multiple sclerosis drug may be used to block HIV infection and reduce the latent reservoir, according to research published in PLOS Pathogens by a team at the RGeorge Washington University.

Newswise: Penn State College of Medicine study explores the association of malaria, HIV with anemia during pregnancy
Released: 12-Aug-2020 3:50 PM EDT
Penn State College of Medicine study explores the association of malaria, HIV with anemia during pregnancy
Penn State College of Medicine

Pregnant women from sub-Saharan Africa with malaria and human immunodeficiency virus (HIV) have a higher prevalence of anemia than pregnant women without infections according to Penn State College of Medicine researchers. The findings may have implications for reducing the risk of death in pregnant women and preventing low birth weights and neurocognitive impairment in their children as a result of anemia.

Newswise: Short-Term Use of HIV-Prevention Medication Protects At-Risk Men on Vacation
Released: 12-Aug-2020 1:05 PM EDT
Short-Term Use of HIV-Prevention Medication Protects At-Risk Men on Vacation
Health Sciences at the University of Pittsburgh

Men at particular risk for HIV are very likely to consistently take prevention medication during vacations when their odds of contracting the virus are higher, according to a new study.

Released: 11-Aug-2020 6:50 PM EDT
Protein uses two antiviral strategies to ward off infections
eLife

To protect humans against infection, a protein called MARCH8 tags the vesicular stomatitis virus (VSV) for destruction while it merely holds HIV hostage, a new study in eLife shows.

Newswise: Coming of Age: Emerging Health Preference Research Based on Established Scientific Standards
Released: 10-Aug-2020 6:35 AM EDT
Coming of Age: Emerging Health Preference Research Based on Established Scientific Standards
ISPOR—The Professional Society for Health Economics and Outcomes Research

Value in Health, the official journal of ISPOR, announced today the publication of a series of articles focused on recent developments in the field of health preference research.

Released: 7-Aug-2020 8:05 PM EDT
Penn Medicine-Led Research Suggests Greater Access to Specific HIV and Tuberculosis Medications is Needed Worldwide
Perelman School of Medicine at the University of Pennsylvania

A specific combination of HIV and TB treatments, difficult to obtain in certain parts of the world, decreased mortality risk for patients with HIV and multidrug-resistant TB

Newswise: New Sugar-based Signature Identifies T Cells Where HIV Hides and Persists Despite Antiretroviral Therapy
Released: 7-Aug-2020 10:30 AM EDT
New Sugar-based Signature Identifies T Cells Where HIV Hides and Persists Despite Antiretroviral Therapy
Wistar Institute

Wistar scientists may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

Released: 4-Aug-2020 11:55 AM EDT
ACTG Announces Launch of Novel Clinical Trial Testing Multiple Therapeutics to Treat COVID-19
University of California, Los Angeles (UCLA), Health Sciences

The AIDS Clinical Trials Group (ACTG) has initiated the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial. ACTIV-2 includes both phase 2 and phase 3 evaluations of multiple promising investigational agents for treating early COVID-19 in a single trial.

Newswise: Caught in the act – microscopy reveals key detail in retrovirus replication
Released: 29-Jul-2020 8:35 AM EDT
Caught in the act – microscopy reveals key detail in retrovirus replication
Penn State College of Medicine

A protein that is critical for retrovirus replication may select viral genetic material for packaging within the nuclei of host cells, rather than in the cytoplasm, as was previously believed.

Newswise: Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Released: 23-Jul-2020 11:00 AM EDT
Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Johns Hopkins Medicine

During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.

Newswise: Pioneering method reveals dynamic structure in HIV
Released: 16-Jul-2020 3:15 PM EDT
Pioneering method reveals dynamic structure in HIV
University of Utah

The method reveals that the lattice, which forms the major structural component of the human immunodeficiency virus (HIV), is dynamic. The discovery of a diffusing lattice made from Gag and GagPol proteins, long considered to be completely static, opens up potential new therapies. The method can be applied to biomedical structure.


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