A new report in JAMA Internal Medicine demonstrates how incorporating blood tests for HIV into standard COVID-19 screening in the emergency department allowed UChicago Medicine to maintain HIV screening volume during the pandemic.
From the very beginning of the AIDS epidemic in 1981, nurses have been at the forefront of patient care, advocacy, and research. But even in the age of antiretroviral therapy and pre-exposure prophylaxis, many challenges remain in reducing the impact of HIV and AIDS, according to the special May/June issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.
Stigma and discrimination, such as homophobia and racism, impede engagement in HIV prevention and use of biomedical tools for treatment in both HIV-negative and HIV-positive gay and bisexual men, according to a Rutgers study.
Cisgender sexual minority men and transgender women are aware of pre-exposure prophylaxis (PrEP), a daily pill for HIV-negative people to prevent HIV infection, but few are currently taking it, according to researchers at Rutgers.
The study, published in the journal AIDS and Behavior, surveyed 202 young sexual minority men and transgender women – two high-priority populations for HIV prevention – to better understand why some were more likely than others to be taking PrEP.
The lab of Rahima Benhabbour, PhD, has received a $3.74 million grant over five years from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH). The grant will fund the creation of an injectable that will provide long-acting protection for women against sexually transmitted pathogens and prevent pregnancy, but is also removable.
The Global Virus Network (GVN), a coalition of the world’s leading medical virology research centers working together to prevent illness and death from viral disease, today announced the election of eight distinguished global leaders to its Board of Directors.
The Global Virus Network, the world’s leading coalition of virologists combatting current and emerging pandemic viral threats and viral causes of disease through international collaborative research response, mourns the passing of its good friend and fellow GVN Board of Directors member, John Martin, PhD.
A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule.
The Institute of Human Virology at the University of Maryland School of Medicine mourns the passing of John Martin, PhD., a leader in supporting access to life-saving anti-HIV medications that although still under patent were made widely and affordably available to millions infected with HIV.
UNC School of Medicine scientists found that HIV boosts a key process in human cells to fuel its replication. They also found that the diabetes drug metformin inhibits that process and thereby suppresses HIV replication in these cells in cell lines and animal models.
Dr. Robert C. Gallo, the Homer and Martha Gudelsky Distinguished Professor in Medicine, director and co-founder of the Institute of Human Virology (IHV) at the University of Maryland School of Medicine, and the co-Founder and International Scientific Advisor of the Global Virus Network, presented “From T Cells and Human Retroviruses to the SARS-CoV-2 Pandemic and Innate Immunity” as the 2021 David Packard Award Lecturer at the Uniformed Services University of the Health Sciences (USU), Monday, March 22.
The proof-of-concept AMP studies demonstrated that a broadly neutralizing antibody (bnAb) called VRC01 was effective at preventing the acquisition of HIV strains to the 30% of strains that were sensitive to the bnAb. This finding was seen both in Sub-Saharan Africa and the U.S. and South America. VRCO1 did not prevent the acquisition of HIV to strains that were resistant to the bNAb.
A study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that just under 20 percent of HIV-uninfected patients visiting Baltimore sexual health clinics were aware of pre-exposure prophylaxis medication (PrEP), a daily regimen that decreases a person’s risk of contracting HIV from sex by more than 90 percent.
Home delivery of HIV medicines in South Africa significantly increased viral suppression compared to those who received clinical care, according to a study by researchers at the University of Washington School of Medicine.
The study was conducted with Amazon.com guidance during COVID-19 restrictions in South Africa.
The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, will present four oral and 20 scientific spotlight sessions at the Conference on Retroviruses and Opportunistic Infections (CROI 2021) held virtually, March 6-10.
April 2021 highlights from AJPH Issue includes COVID-19-related articles around deaths linked to unemployment, higher than reported death toll in Florida and crowdfunding campaigns spreading misinformation
In 2019, the U.S. rolled out a new initiative aimed at ending the HIV epidemic by the year 2030. In a new analysis published in The Lancet, Carlos Rodriguez-Diaz, an Associate Professor at the George Washington University, suggests that initiative will fail unless the U.S. addresses the rising rates of HIV infection in Latinx sexual and gender minority populations.
Using venom from the Conus nux, a sea snail, a first-of-its-kind study suggests these conotoxins could potentially treat malaria. The study provides important leads toward the development of new and cost-effective anti-adhesion or blockade-therapy drugs aimed at counteracting the pathology of severe malaria. Similarly, mitigation of emerging diseases like COVID-19 also could benefit from conotoxins as potential inhibitors of protein-protein interactions as treatment. Venom peptides from cone snails has the potential to treat myriad diseases using blockage therapies.
The AIDS Clinical Trials Group has added rapid infusion, intramuscular injection, an inhalant, and an oral agent to its ACTIV-2 phase 2 and 3 evaluations of multiple investigational agents for treating early, symptomatic COVID-19 in a single trial for outpatient treatment.
Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE.
SEATTLE —Feb. 4, 2021 —Below are summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.We are looking forward to the Transplantation & Cellular Therapy Meetings, to be held online Feb. 8-12. Read highlights of Fred Hutch research to be presented, including on COVID-19 and cancer and new insights on treating graft-vs.
Researchers at Washington University School of Medicine in St. Louis have identified a potential way to eradicate the latent HIV infection that lies dormant inside infected immune cells. Studying human immune cells, the researchers showed that such cells have a natural alarm system that detects the activity of a specific HIV protein. Rather than attack the virus based on appearance, this strategy is to attack the virus based on what it is doing — vital activities that are required for the virus to exist.
New research out of the University at Albany and the AIDS Institute at the New York State Department of Health found that through the middle of 2020, people diagnosed with HIV infection were significantly more likely to contract, be hospitalized with and die from COVID-19.
Shyam Kottilil, MBBS, PhD, professor of medicine at the University of Maryland School of Medicine (UMSOM), and Director of UMSOM’s Institute of Human Virology (IHV) Division of Clinical Care and Research, has been awarded Mastership in the American College of Physicians (ACP), the national organization of internists.
The National Institutes of Health (NIH) awarded Professor Mahesh Mohan, D.V.M., Ph.D., and collaborators more than $3.5 million over five years to investigate the effects of cannabinoids on Human Immunodeficiency Virus (HIV) associated neurocognitive disorder (HAND). This research project aims to evaluate whether delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) alone or in combination can potentially alter DNA methylation, which is a biological process that can create a change in the expression of certain genes.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
SEATTLE – Dec. 2, 2020 – Below are summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.If you’re following the American Society of Hematology’s annual meeting (virtual, Dec. 5-8), see our media tip sheet highlighting Fred Hutch presentations and activities, including those by current ASH president Dr.
This World AIDS Day, the Forum of International Respiratory Societies (FIRS), of which the ATS is a founding member, is calling on governments, health advocates and non-government organizations to strengthen their response to AIDS and tuberculosis, and to ensure that TB services are maintained throughout their response to COVID-19.
The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, has been re-funded for the next seven years by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and collaborating NIH Institutes.
Highlights from January 2021 issue of AJPH. Better use of HIV prevention funds could substantially cut new infections; Study explores link between natural disasters, onset of headaches, digestive and back problems; Backpack medicine a promising way to reach people who are homeless during COVID-19; Successful contact tracing programs require a sustainable workforce
Rutgers School of Public Health instructor, Stephanie Shiau, has been awarded a Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health R21 grant to examine the effect of HIV infection and/or exposure during pregnancy on epigenetic patterns in children.
Study finds that in a diverse, global patient population, a minimal monitoring (MINMON) approach to hepatitis C treatment was safe and achieved comparable sustained virologic response (SVR) to current standard of care.
A team of scientists from Albert Einstein College of Medicine has received a five-year, $4.9 million grant from the National Institutes of Health (NIH) to establish a research center to investigate HIV- and human papillomavirus (HPV)-related cancers in Africa.
Robert C. Gallo, MD, the Homer & Martha Gudelsky Distinguished Professor in Medicine at the University of Maryland School of Medicine (UMSOM) and Co-Founder & Director of the UMSOM’s Institute of Human Virology (IHV), announced today that a team of leading scientists in human immunology, virology and stem cell biology, led by Lishan Su, PhD joined IHV on October 1 with academic appointments in the UMSOM Department of Pharmacology. As part of the Maryland E-Nnovation Initiative Fund (MEIF) to recruit top research faculty and a donation to IHV from the Charles Gordon Estate, Dr. Su has been named the Charles Gordon Smith Endowed Professor for HIV Research. Dr. Su will also head IHV’s Division of Virology, Pathogenesis and Cancer.
Researchers at Louisiana State University Health Sciences Center in New Orleans honed in on one population particularly at risk during the pandemic: people living with HIV with at-risk alcohol use. They surveyed 80 people living with HIV in Louisiana during that state’s stay-at-home order, recruiting participants from the ongoing longitudinal Aging in Louisiana: Immunosenescence, HIV and Socioenvironmental Factors-Exercise (ALIVE-Ex) study.
Untreated HIV infection is linked with epigenetic changes suggesting rapid aging. A new study by UCLA researchers shows that antiretroviral therapy given over two years was unable to completely restore age-appropriate epigenetic patterns, leaving patients more susceptible to aging-related illnesses.
Cultural taboos may leave Muslim American adolescents uninformed about romantic relationships and sex, placing them at risk of HIV and other sexually transmitted infections (STIs). A sex education program designed specifically for Muslim teens – with a foundation in Islamic morals and values – is reported in the November/December issue of The Journal of the Association of Nurses in AIDS Care (JANAC). The official journal of the Association of Nurses in AIDS Care, JANAC is published in the Lippincott portfolio by Wolters Kluwer.
Researchers with the Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have secured $4 million in funding from the National Institutes of Health (NIH)/National Cancer Institute (NCI) to establish an HIV-associated Malignancy Research Center focused on lung cancer in East Africa.
Accomplishing a feat that had been a pipe dream for decades, scientists at University of Utah Health and University of Virginia have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome). Doing so has provided up-close access to the virus—which is otherwise obstructed from view deep within the cell—and enabled identification of essential components that HIV needs to replicate within its human host. The research publishes in the journal, Cell.
In a new study, infectious disease researchers show that HIV viremia isn’t always nonadherence to medication or resistance to the drugs. Instead, the patients are victims of what the scientists have dubbed “repliclones” – large clones of HIV-infected cells that produce infectious virus particles.
The Chicago Center for HIV Elimination, housed at the University of Chicago, has been awarded $5 million over two years through the National Institute of Health’s (NIH) RADx Underserved Populations program to support a COVID-19 testing project to engage two disenfranchised populations.