A new study by researchers at Children’s Hospital of Philadelphia (CHOP) has demonstrated that IgA acts as a “tuner” that regulates the number of microbes the body sees every day, restraining the systemic immune response to these commensal microbes and limiting the development of systemic immune dysregulation.
A global phase 3 clinical trial that included Ann & Robert H. Lurie Children’s Hospital of Chicago found that a year-long immunotherapy through a skin patch safely desensitized toddlers with peanut allergy, lowering the risk of a severe allergic reaction from accidental exposure. Results of this randomized, double-blind, placebo-controlled trial for children 1-3 years of age, funded by DBV Technologies, were published in the New England Journal of Medicine.
Food allergies pose a significant health risk, resulting in numerous hospitalizations every year, as even trace amounts of allergens can trigger severe reactions. Cross-contamination of food products can happen easily in the production process, so it’s important to have reliable methods of testing for allergens. A new study conducted at the University of Illinois explores the application of near-infrared (NIR) spectroscopy to detect three types of allergens in quinoa flour. The researchers say the method is fast, easy, non-invasive, inexpensive, and highly accurate.
Skin cancer is the most prevalent form of cancer in the United States, with over 5 million cases diagnosed annually. The Centers for Disease Control and Prevention reports that melanoma alone accounts for more than 8,000 deaths each year. Thankfully, skin cancer is highly preventable, making it crucial to prioritize protection. Below are some of the latest headlines in the Dermatology channel.
Experts from Indiana University are available to comment on trending topics for the week of May 8, including the Writer's Guild of America strike, the ongoing investigation into the leak of classified military documents on Discord, and the role of climate change in an early allergy season.
The immune system has a biological telecommunications system — small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.
Upon an arrival to the emergency department for abdominal pain of unknown cause, most non-pregnant adult patients receive a CT scan with IV contrast to diagnose the source of the pain. However, IV contrast can be a risk in patients with severe kidney disease or at risk for an allergic reaction from the dye. When scans are performed without IV contrast, though, they are usually less accurate, which can lead to misdiagnosis.
Researcher will discuss the study which involved a sleeping aid known as suvorexant that is already approved by the Food and Drug Administration (FDA) for insomnia, hints at the potential of sleep medications to slow or stop the progression of Alzheimer’s disease.
According to a new Finnish study, greenness around the home in early childhood does not seem to protect children from atopic eczema. Instead, the proximity of coniferous, mixed forests and agricultural areas was associated with elevated risk of eczema. The effect was seen especially in children who were born in the spring.
The key to understanding allergies may lie in genetic and environmental triggers as well as a person’s lifestyle. A Penn State Health physician discusses what causes seasonal allergies and how to alleviate the symptoms.
May is Asthma and Allergy Awareness Month. Experts from the American College of Allergy, Asthma & Immunology caution that pollen season is starting earlier and lasting longer than in past decades.
Penn State College of Medicine researchers have found Black and Hispanic patients with severe allergies are less likely to get a common treatment, allergen immunotherapy, compared to white patients.
A new survey of allergists/immunologists from the American College of Allergy, Asthma and Immunology shows that diagnosing, treating and managing hereditary angioedema can be challenging for patients and healthcare providers - including patients in rural areas. An article about the survey is published in Annals of Allergy, Asthma and Immunology, ACAAI’s scientific journal.
For more than 20 years, Loyola Medicine's Gottlieb Memorial Hospital has provided the Chicago area with updated allergy counts every weekday during allergy season.
In an analysis of over 65,000 infants from Japan, children exposed to pet cats or indoor dogs during fetal development or early infancy tended to have fewer food allergies compared to other children.
Rising temperatures and higher CO₂ levels are fueling longer and more intense pollen seasons, negatively impacting the health of those with allergies. A medical expert and public health scientist both offer strategies to fight back.
Along with UNC colleagues Scott Commins, MD, PhD, and Michael Croglio, MD, McGill was one of the first to describe the condition in gastroenterology patients. McGill has now published a national clinical practice update in the journal Clinical Gastroenterology and Hepatology of the American Gastroenterological Association.
The American Gastroenterological Association (AGA) has released new clinical guidance to help physicians and patients identify if unexplained digestive symptoms are due to alpha-gal syndrome, a food allergy that is caused by lone star tick bites.
Spring has arrived. The new season is bringing budding trees and blossoming flowers, along with runny and stuffy noses, sneezes and itchy, watery eyes.
A four-year phase 2 clinical trial demonstrated that a peanut allergy treatment called sublingual immunotherapy, or SLIT, is effective and safe, while offering durable desensitization to peanuts in peanut-allergic children.
Millions of people in the U.S. report having a metal allergy, and current estimates state that 10 percent of Americans will receive a medical implant during their lifetime.
Psoriasis and eczema affect men and women differently, with women needing to take extra precautions when considering treatments if they’re planning for pregnancy.
New research shows that as wildfires are increasing in frequency, intensity and extent, and affecting air quality across the U.S., they are having a detrimental effect on people with and without skin conditions.
Many people keen to reduce their meat consumption are turning to substitutes made of legumes packed with protein, vitamins, and fiber. But allergies to legumes like soy or peanuts are both common and dangerous.
It's sleep awareness week, according to the National Sleep Foundation. It’s important to understand how sleep deprivation can impact your health. Most people recognize that if they don’t get enough sleep, their mood and memory will suffer the next day.
Parents of children with allergies and asthma often face an added layer of concern about summer camp as they wonder how they will keep their kids safe from allergy and asthma flares, while allowing them to have great summer fun.
It’s almost that dreaded time of year, when spring and summer allergies can make life miserable for many. Ashley Agan, M.D., Assistant Professor in the Department of Otolaryngology – Head and Neck Surgery at UT Southwestern Medical Center, said steps can be taken to control symptoms and prevent infections.
عزيزتي مايو كلينيك: أنا جدة لثلاثة أحفاد رائعين. حفيدي الأكبر يعاني من عدم تحمل اللاكتوز. وفي الفترة الأخيرة، تم تشخيص حفيدي الأصغر بحساسية الفول السوداني. ما الفرق بين عدم تحمل الطعام وحساسية الطعام؟
الإجابة: تختلف الحياة على مائدة العشاء لآلاف الأشخاص في الولايات المتحدة المصابين بأحد أنواع حساسية الطعام. تظهر الدراسات الحديثة أن ما يقرب من 5% من الأطفال دون سن الخامسة، و3% من البالغين يعانون من أنواع حساسية الطعام. يتراوح انتشار حساسية الطعام في جميع أنحاء العالم من 1.1% إلى 10.8%.
ESTIMADA MAYO CLINIC: Sou avó de três netos maravilhosos. Meu neto mais velho é intolerante à lactose. Recentemente, meu neto mais novo foi diagnosticado com alergia a amendoim. Qual é a diferença entre intolerância e alergia alimentar?
RESPOSTA: A rotina à mesa de jantar é diferente para milhares de pessoas nos Estados Unidos que têm alguma alergia alimentar.
Soy abuela de tres grandiosos nietos. Mi nieto mayor tiene intolerancia a la lactosa. Hace poco, a mi nieto menor le diagnosticaron alergia al cacahuate (maní). ¿Cuál es la diferencia entre la intolerancia y la alergia alimentaria?
Papers on the use of AI in physiologically based pharmacokinetic modeling, how mild allergic airway responses may increase cardiovascular risk, and how single-cell transcriptomes can show dose-dependent disruption of hepatic zonation by TCDD are featured in lastest issue of Toxicological Sciences.
A faculty member of Chulalongkorn University’s Faculty of Science has researched and developed high-protein, gluten-free pasta noodles for gluten-intolerant health-lovers.
Mount Sinai researchers have been awarded $12 million over five years by the National Institutes of Health to create a center to elucidate novel causes of, and contributing factors to, food allergies and atopic dermatitis. The Systems Biology of Early Atopy (SunBEAm) Analysis and Bioinformatics Center intends to develop a better understanding of allergy development. The center will apply systems biology to identify early-life markers of risk for food allergies and atopic dermatitis (also known as eczema), as well as biological pathways underlying these common conditions, through the profiling and analysis of longitudinal multi-omics data from a multi-center pre-birth cohort of 2,500 children.
Spring allergy symptoms will start to appear soon in parts of the country. Many allergists advise their patients to set a reminder for Valentine’s Day to start taking allergy medications.
Boiling peanuts for up to 12 hours could help overcome children’s allergic reactions according to the results of a clinical trial at Flinders University and SAHMRI which found up to 80% of children with peanut allergy became desensitised to eating peanuts.
A special article in Annals of Allergy, Asthma and Immunology reports on the findings of a roundtable discussion that focused on challenges that people with skin of color with atopic dermatitis and food allergy often experience based on their skin type, their comfort level with health care providers, where they live, and many other sociodemographic factors.