The harder your brain works at your job, the less likely you may be to have memory and thinking problems later in life, according to a new study published in the April 17, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
“Are the risk factors for early onset Alzheimer’s the same as late onset?” asks Domenico Praticò, MD, the Scott Richards North Star Foundation Chair for Alzheimer’s Research, Professor in the Departments of Pharmacology and Microbiology, and Director of the Alzheimer’s Center at Temple (ACT), at the Lewis Katz School of Medicine at Temple University (LKSOM)
Caring for someone with dementia or Alzheimer’s disease is challenging. In addition to the financial and physical demands, many caregivers are unprepared for the stress of trying to effectively communicate with a loved one who may be prone to agitation, verbal aggression, and hallucinations.
A changing climate may be linked to growing death and disability from stroke in regions around the world, according to a study published in the April 10, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Racial discrimination experienced during midlife is associated with Alzheimer’s disease pathology, according to a new study from researchers at Wake Forest University School of Medicine and the University of Georgia. The findings appear online today in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.
In findings published in Cell Reports, senior author Jerold Chun, M.D., Ph.D., and team also discovered that the biological instructions within these vesicles differed significantly in postmortem brain samples donated from patients suffering from Alzheimer’s disease.
Proteins known as oligomeric chaperones help suppress the formation of misshaped proteins that cause a variety of degenerative and neurodegenerative diseases, such as Alzheimer’s, Huntington’s, and Parkinson’s. In a new study, UT Southwestern Medical Center researchers identified a key feature necessary for one of these oligomeric chaperones, known as DNAJB8, to assemble from disparate parts and showed that the parts alone can reshape misfolded proteins. The findings, published in Structure, could lead to better ways to diagnose and treat these conditions.
Researchers from the Perelman School of Medicine at the University of Pennsylvania will present data on the latest research across the full spectrum of Neurology – including a link between head injury and suicide, potential traumatic brain injury biomarkers, a promising new drug to treat multiple sclerosis – at the American Academy of Neurology (AAN) Annual Meeting from April 13-18 in Denver, Colorado. Follow us on Twitter @PennMedicine and @PennMDForum for updates.
A research team led by Dr. Kim Yun Kyung from the Brain Science Institute at the Korea Institute of Science and Technology (KIST), in collaboration with Professor Chang Young-Tae's team from Pohang University of Science and Technology, has announced the development of a next-generation neuron labeling technology called NeuM.
A new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood to the brain. The work is being presented this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society.
Earlier menopause combined with higher risk of cardiovascular disease is linked to an increased risk of thinking and memory problems later, according to a new study published in the April 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. In this study, earlier menopause is defined as occurring before age 49.
Scientists at Washington University School of Medicine in St. Louis have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer’s disease plaques and the LILRB4 receptor on microglia cells (purple) activates them to clean up damaging plaques (blue) in the brain.
A new study recently published in Nature Structural and Molecular Biology uses leading-edge cryo-electron microscopy imaging technology to determine whether differences exist between the protein structures in those with Alzheimer’s disease and those with both Alzheimer’s disease and Down syndrome.
Expert shares insight on how to support this new generation of caregivers
A gene therapy developed by researchers at UT Southwestern Medical Center for a rare disease called giant axonal neuropathy (GAN) was well tolerated in pediatric patients and showed clear benefits, a new study reports. Findings from the phase one clinical trial, published in the New England Journal of Medicine, could offer hope for patients with this rare condition and a host of other neurological diseases.
Just as you can’t make an omelet without breaking eggs, scientists at Albert Einstein College of Medicine have found that you can’t make long-term memories without DNA damage and brain inflammation. Their surprising findings were published online today in the journal Nature.
A new study found higher levels of neurodegeneration in rats that consumed reused deep fried cooking oils and their offspring compared to rats on a normal diet.
A new study published in JAMA Neurology found human brains are getting bigger. The increased size may lead to a brain reserve, potentially reducing the risk of dementia.
New research conducted in mice offers insights into what’s going on at the molecular level that could cause people with diabetes to develop Alzheimer’s disease.
Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer’s and other diseases.
According to new research at Case Western Reserve University, connecting with friends is key to limiting social isolation—something researchers believe could also reduce Alzheimer’s, dementia
Dementia stands as one of the most significant global health challenges of the 21st century, with over 50 million individuals worldwide currently affected, a number projected to triple by 2050, reaching 152 million, due to global population aging.
A collaborative effort between Israeli and Italian researchers has led to the development of a new treatment strategy targeting the early-stage aggregation of A-beta before the formation of toxic oligomers.
University of Delaware researchers are studying how the brain controls movement and how motor skills are learned in health and disease.
For the first time, researchers at the University of Minnesota Twin Cities showed that non-invasive brain stimulation can change a specific brain mechanism that is directly related to human behavior.
“While our research does not prove that veterans who experienced these injuries will develop Alzheimer’s disease, it raises the possibility that they may be on a pathway leading to dementia,” said Dr. Ge Li, the paper's first author and an associate professor of psychiatry and behavioral sciences at UW Medicine.
Chula Medicine has designed an anti-choke mug with calculated angle, amount, and time of water flow from the mug to the patient’s lips hoping to reduce choking that may lead to lung infection, bring peace of mind to caregivers, and make it safer for patients who will have a better quality of life.
Middle-age veterans who experienced concussions due to blasts from explosive devices may have biomarkers in their spinal fluid similar to people who develop Alzheimer’s disease, according to a new study published in the March 13, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Gait impairments often are prevalent in the early stages of cognitive decline. Researchers quantitatively compared straight walking and curved walking – a more natural yet complex activity – in healthy older adults and adults with mild cognitive impairment (MCI). A depth camera detected and tracked 25 joints of body movement and signals were processed to extract 50 gait markers. Intriguingly, curved walking illuminated notable disparities between the study groups.
Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer’s disease, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
Dementia may be three times more common among people with essential tremor, a movement disorder that causes involuntary shaking, than the general population, according to research released today, March 6, 2024. The study will be presented at the American Academy of Neurology’s 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online.
New Cleveland Clinic-led research points to sildenafil (Viagra) as a potential treatment for Alzheimer’s disease. The study provides evidence from computational models, insurance claims data and observations from brain cells in Alzheimer’s patients. Sildenafil is the main component of drugs used to treat erectile dysfunction (Viagra) and pulmonary arterial hypertension (Revatio).
Four University of Michigan research teams have made the bracket of 64 teams for STAT Madness, a virtual tournament of science. They were picked for their groundbreaking work on brain cancer, heart transplant, dementia care and deadly fungal infections published in 2023.
Alzheimer’s disease and Type 2 diabetes are part of a family of amyloid diseases that are characterized by having proteins that cluster together. University of Washington researchers have demonstrated more similarities between the two diseases.
Continuous, unobtrusive sensors and related monitoring devices are installed in older drivers’ vehicles to detect changes in highly complex activities over time. A driver facing camera, forward facing camera, and telematics unit provide video in real-time to enable researchers to analyze abnormal driving such as getting lost, reaction time and braking patterns as well as travel patterns such as miles driven, miles during the night and daytime, and driving in severe weather. Detecting changes in behavior could generate early warning signs of possible changes in cognition.
Researchers at Washington University School of Medicine in St. Louis have found that brain cell activity during sleep is responsible for propelling fluid into, through and out of the brain, cleaning it of debris.
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. The study, published in the February 28 online issue of Communications Medicine, addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk. Unlike previous studies that focused on diagnosing dementia, this research delves into predicting patient prognosis, shedding light on mortality risks and contributing factors in various kinds of dementia.
UC Santa Barbara researchers and collaborators in Colombia, Brazil and Germany are progressing toward an understanding of mechanisms that underlie Alzheimer’s disease, in particular an early-onset, genetic form that has afflicted generations of an extended family in Colombia.
As we get older, we may start to notice it takes us longer to find the right words. This can lead to concerns about cognitive decline and dementia.
The impact of abdominal fat on brain health and cognition is generally more pronounced in middle-aged men at high risk of Alzheimer’s disease as opposed to women, according to researchers at Rutgers Health.
Two new studies from the University of Chicago investigate the roles of the gut microbiome and estrogen in the differing rates of Alzheimer’s disease among women and men.
Neuroscientist Emily Rogalski, PhD, is a principal investigator on a grant from the NIH to support a clinical trial of a telehealth intervention for primary progressive aphasia (PPA).
A new UCLA Health study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer’s disease including restoring neural pathways, preventing brain matter decline and reversing aging and inflammation-associated biomarkers – improvements not seen in a group who received standard memory training exercises.
People with higher exposure to traffic-related air pollution were more likely to have high amounts of amyloid plaques in their brains associated with Alzheimer’s disease after death, according to a study published in the February 21, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Stay informed! These are the latest research articles on "Long COVID" from the Coronavirus News Source on Newswise.
Researchers at West Virginia University have identified a set of diagnostic metabolic biomarkers that can help them develop artificial intelligence tools to detect Alzheimer’s disease in its early stages, as well as determine risk factors and treatment interventions.
A team led by scientists at the Case Western Reserve University School of Medicine has identified a new therapeutic approach for combating neurodegenerative diseases.
Rutgers study led by undergrads and gap-year students breaks ground in the field of neuroscience and suggests experimental medication could treat dementia.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right
