Feature Channels: Alzheimer's and Dementia

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Released: 19-May-2022 2:20 PM EDT
How cranberries could improve memory and ward off dementia
University of East Anglia

Adding cranberries to your diet could help improve memory and brain function, and lower ‘bad’ cholesterol – according to new research from the University of East Anglia (UK).

12-May-2022 4:00 PM EDT
Risk Factors for Dementia May Vary with Age
American Academy of Neurology (AAN)

Which vascular risk factors are associated with the risk of developing dementia may vary with age. A new study shows that among people around age 55, the risk of developing dementia over the next 10 years was increased in those with diabetes and high blood pressure. For people around 65 years old, the risk was higher in those with heart disease, and for those in their 70s, diabetes and stroke. For 80-year-olds, the risk of developing dementia was increased in those with diabetes and a history of stroke, while taking blood pressure medications decreased the risk. The study is published in the May 18, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 17-May-2022 1:45 PM EDT
Stress could make us more likable, and other Behavioral Science news tips
Newswise

Here are some of the latest articles added to the Behavioral Science channel on Newswise.

Released: 13-May-2022 7:00 AM EDT
Factors Predicting Engagement of Older Adults With a Coach-Supported eHealth Intervention Promoting Lifestyle Change and Associations Between Engagement and Changes in Cardiovascular and Dementia Risk: Secondary Analysis of an 18-Month Multinational
Journal of Medical Internet Research

Background: Digital health interventions could help to prevent age-related diseases, but little is known about how older adults engage with such interventions, especially in the long term, or whether engagement is associated with cha...

Released: 12-May-2022 10:35 AM EDT
Dementia: Combination of “feelings” and measurements suggest Alzheimer’s in the early stage
DZNE -- German Center for Neurodegenerative Diseases

Subjective memory disorders in conjunction with conspicuous levels of beta-amyloid proteins in the cerebrospinal fluid are a strong indication of developing Alzheimer’s disease.

9-May-2022 8:05 AM EDT
Study Finds Increased Risk of Dementia After Hospitalization for Major TBI
American Academy of Neurology (AAN)

People who have been hospitalized for a major traumatic brain injury (TBI) may have a higher risk of developing dementia when compared to people who do not have a TBI, according to a new study published in the May 11, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 9-May-2022 3:10 PM EDT
Quantifying Cognitive Decline in Dogs Could Help Humans With Alzheimer’s Disease
North Carolina State University

A suite of complimentary tests can quantify changes in dogs suspected of suffering from cognitive decline. The approach could benefit dogs and serve as a model for evaluating cognitive decline progression in – and treatments for – humans with Alzheimer’s disease.

Released: 9-May-2022 3:00 PM EDT
Factors Predicting Engagement of Older Adults With a Coach-Supported eHealth Intervention Promoting Lifestyle Change and Associations Between Engagement and Changes in Cardiovascular and Dementia Risk: Secondary Analysis of an 18-Month Multinational
Journal of Medical Internet Research

Background: Digital health interventions could help to prevent age-related diseases, but little is known about how older adults engage with such interventions, especially in the long term, or whether engagement is associated with cha...

Released: 6-May-2022 9:50 AM EDT
‘Stressed’ cells offer clues to eliminating build-up of toxic proteins in dementia
University of Cambridge

It’s often said that a little stress can be good for you. Now scientists have shown that the same may be true for cells, uncovering a newly-discovered mechanism that might help prevent the build-up of tangles of proteins commonly seen in dementia.

Newswise: Cedars-Sinai Experts to Present New Research and Discuss Advances in Care for Older Adults
Released: 5-May-2022 11:50 AM EDT
Cedars-Sinai Experts to Present New Research and Discuss Advances in Care for Older Adults
Cedars-Sinai

Cedars-Sinai geriatrics experts will present their latest advances in research and care in person at the annual scientific meeting of the American Geriatrics Society (AGS) in Orlando May 12-14, sharing innovations to improve both the quality of patient care and quality of life for older adults.

28-Apr-2022 3:50 PM EDT
Higher Antioxidant Levels Linked to Lower Dementia Risk
American Academy of Neurology (AAN)

People with higher levels of antioxidants in their blood may be less likely to develop dementia, according to a study published in the May 4, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 4-May-2022 12:40 PM EDT
Hearing and vision impairment linked to serious cognitive impairment in older adults
University of Toronto

A new nationally representative study published online in the Journal of Alzheimer’s Disease Reports found hearing impairment and vision impairment to be independently associated with cognitive impairment.

29-Apr-2022 7:05 PM EDT
Study of Promising Alzheimer’s Marker in Blood Prompts Warning About Brain-Boosting Supplements
University of California San Diego

Elevated levels of an enzyme called PHGDH in the blood of older adults could be an early warning sign of Alzheimer’s disease. Research led by UC San Diego has consistently found high levels of PHGDH expression in brain tissue and blood samples of older adults with different stages of the disease.

Released: 2-May-2022 3:45 PM EDT
阿尔茨海默病的新计算模型
Mayo Clinic

妙佑医疗国际(Mayo Clinic) 研究人员提出了一种新的计算模型,用于在阿尔茨海默病症状与脑解剖结构之间建立起映射关系。该模型是通过将机器学习技术应用于患者大脑成像数据而开发的。这个模型利用大脑的完整功能,而不是特定的大脑区域或网络来解释脑解剖结构与心理过程之间的关系。研究结果已发表在《自然通讯》杂志上。

Released: 2-May-2022 3:25 PM EDT
اقتراح نموذج محوسب جديد لداء الزهايمر
Mayo Clinic

مدينة روتشستر، ولاية مينيسوتا- اقترح باحثو مايو كلينك نموذجًا جديدًا لرسم خرائط أعراض داء الزهايمر في تشريح الدماغ. وتم تطوير هذا النموذج عبر إجراء التعلم الآلي على بيانات تصوير دماغ المرضى، حيث يستخدم الوظيفة الكاملة للدماغ بدلًا من استخدام مناطق أو شبكات دماغية محددة لشرح العلاقة بين تشريح الدماغ ومعالجة الدماغ للعمليات. وتم نشر النتائج في نيتشر كوميونيكيشنز.

Released: 2-May-2022 3:20 PM EDT
Novo modelo computacional proposto para a doença de Alzheimer
Mayo Clinic

Pesquisadores da Mayo Clinic propuseram um novo modelo para mapear os sintomas da doença de Alzheimer na anatomia do cérebro. Esse modelo foi desenvolvido aplicando o processo de aprendizagem de uma máquina a dados de imagens de cérebros de pacientes.

Released: 2-May-2022 3:10 PM EDT
Proposición de modelo computacional para la enfermedad de Alzheimer
Mayo Clinic

Los investigadores de Mayo Clinic propusieron un nuevo modelo para hacer un mapa de los síntomas de la enfermedad de Alzheimer en la anatomía cerebral. El modelo se creó mediante la aplicación de aprendizaje automático a los datos de imágenes cerebrales de los pacientes.

Newswise: Scientists Detail Brain Dynamics Implicated in Neurological Conditions
Released: 2-May-2022 10:05 AM EDT
Scientists Detail Brain Dynamics Implicated in Neurological Conditions
University of North Carolina School of Medicine

This research in mice provides evidence for how dynamics in the default mode network of the brain are altered by activating the locus coeruleus region – a small nucleus in the brainstem that releases norepinephrine. It also suggests new targets for treatment to restore DMN function.

Newswise: 'Eye-Catching' Smartphone App Could Make It Easy to Screen for Neurological Disease at Home
Released: 29-Apr-2022 1:45 PM EDT
'Eye-Catching' Smartphone App Could Make It Easy to Screen for Neurological Disease at Home
University of California San Diego

UC San Diego researchers developed a smartphone app that could allow people to screen for Alzheimer's disease, ADHD and other neurological diseases and disorders—by recording closeups of their eye. The app uses a smartphone's built-in near-infrared camera and selfie camera to track how a person's pupil changes in size. These pupil measurements could be used to assess a person's cognitive condition.

Released: 29-Apr-2022 11:05 AM EDT
Insulin Spray Improved Gait, Cognitive Function in Patients with and Without Type 2 Diabetes, Clinical Trial Shows
Beth Israel Deaconess Medical Center

Scientists have assessed the long-term effects of intranasal insulin on cognition and on gait in people with and without type 2 diabetes mellitus.

Newswise: Tufts University Researchers Discover New Function Performed by Nearly Half of Brain Cells
28-Apr-2022 8:45 AM EDT
Tufts University Researchers Discover New Function Performed by Nearly Half of Brain Cells
Tufts University

Researchers at Tufts University School of Medicine have discovered a previously unknown function performed by a type of cell that comprises nearly half of all cells in the brain. The scientists say this discovery in mice of a new function by cells known as astrocytes opens a whole new direction for neuroscience research that might one day lead to treatments for many disorders ranging from epilepsy to Alzheimer’s to traumatic brain injury.

Released: 27-Apr-2022 5:05 PM EDT
New research identifies blood biomarker for predicting dementia before symptoms develop
National University of Ireland, Galway (NUI Galway)

New research from NUI Galway and Boston University has identified a blood biomarker that could help identify people with the earliest signs of dementia, even before the onset of symptoms.

Released: 27-Apr-2022 3:00 PM EDT
6G and Artificial Intelligence Technologies for Dementia Care: Literature Review and Practical Analysis
Journal of Medical Internet Research

Background: The dementia epidemic is progressing fast. As the world’s older population keeps skyrocketing, the traditional incompetent, time-consuming, and laborious interventions are becoming increasingly insufficient to address d...

Released: 27-Apr-2022 1:35 PM EDT
New data shows burden of dementia symptoms just as high in community population as nursing home residents
Regenstrief Institute

New data shows that the symptoms suffered by people with advanced Alzheimer’s disease and related dementias who live in the community occur at a strikingly similar rate to those of dementia patients in a nursing home.

Released: 26-Apr-2022 3:05 PM EDT
MSU research could lead to new Alzheimer’s treatments
Michigan State University

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology. The researchers revealed a new way that nature can inhibit or switch off important proteins known as intramembrane proteases — pronounced “pro tea aces” — which the team reported April 26th in the journal eLife.

Newswise: NIH awards Joseph Mikels $2.6 million to research motivation and health
Released: 26-Apr-2022 2:55 PM EDT
NIH awards Joseph Mikels $2.6 million to research motivation and health
DePaul University

Tapping into positive emotions and social connections may be key to motivating older adults to exercise. DePaul University psychology professor Joseph Mikels has been awarded a $2.6 million grant from the National Institutes of Health to continue his work on emotion, aging and decision-making throughout the life span.

Released: 26-Apr-2022 1:55 PM EDT
Talk therapy may alleviate depression and improve quality of life for people with dementia
University College London

Feelings of anxiety and depression are common in people living with dementia and mild cognitive impairment, but the best way to treat these symptoms is currently unknown, as medicines often used to treat these symptoms may not be effective for people with dementia and may cause side effects.

Newswise: Albert Einstein College of Medicine Receives $4.2 Million NIH Grant to Discover Novel Markers of Early Alzheimer’s Disease
Released: 26-Apr-2022 10:00 AM EDT
Albert Einstein College of Medicine Receives $4.2 Million NIH Grant to Discover Novel Markers of Early Alzheimer’s Disease
Albert Einstein College of Medicine

Diagnosing Alzheimer's disease can be a complex and time-consuming process, requiring evaluations ranging from brain scans to cognitive and lab tests to reviews of medical history and symptoms. Simpler and faster ways to diagnose the disease are urgently needed. Researchers at Albert Einstein College of Medicine have been awarded a five-year, $4.2 million National Institutes of Health (NIH) grant to detect behavioral markers for Alzheimer’s that are present early in the course of the disease, before it can be clinically diagnosed. Results could help scientists identify people at risk for Alzheimer’s and related problems, such as falls, and lead to new preventive strategies.

Newswise: When it Comes to Preventing Alzheimer’s, Women and Men are Not Created Equal
22-Apr-2022 5:00 PM EDT
When it Comes to Preventing Alzheimer’s, Women and Men are Not Created Equal
Florida Atlantic University

A study is the first to examine if sex significantly affects cognitive outcomes in people who follow individually-tailored, multi-domain clinical interventions. The study also determined whether change in risk of developing cardiovascular disease (CVD) and Alzheimer’s disease (AD), along with blood markers of AD risk, also were affected by sex. Results showed that while care in an Alzheimer's Prevention Clinic setting is equally effective at improving cognitive function in both women and men, the personally-tailored interventions used by the researchers led to greater improvements in women compared to men across AD and CVD disease risk scales, as well blood biomarkers of risk such as blood sugar, LDL cholesterol, and the diabetes test HbA1C. Findings are important because women are disproportionately affected by AD and population-attributable risk models suggest that managing risk factors can prevent up to one-third of dementia cases.

20-Apr-2022 4:05 PM EDT
Race of People Given Alzheimer’s Blood Tests May Affect Interpretation of Results
Washington University in St. Louis

Three of four blood tests used to identify people in early stages of Alzheimer’s disease perform differently in Black individuals compared to white individuals, according to a new study from Washington University School of Medicine in St. Louis. Such differences may put Black patients at risk of misdiagnosis.

Released: 20-Apr-2022 5:05 PM EDT
Single-cell DNA sequencing offers a new angle on the causes of Alzheimer’s disease
Boston Children's Hospital

Alzheimer’s disease is marked by a loss of functional neurons in the brain.

Released: 20-Apr-2022 4:55 PM EDT
Genetic changes differed, increased in people with Alzheimer’s disease
Brigham and Women’s Hospital

Inside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer’s disease, these errors — known as somatic mutations — may build up at a faster rate.

14-Apr-2022 5:00 PM EDT
Faster Accumulation of Cardiovascular Risk Factors Linked to Increased Dementia Risk
American Academy of Neurology (AAN)

Cardiovascular disease risk factors, like high blood pressure, diabetes, obesity and smoking, are believed to play key roles in the likelihood of developing cognitive decline, dementia, and Alzheimer’s disease. A new study suggests that people who accumulate these risk factors over time, at a faster pace, have an increased risk of developing Alzheimer’s disease dementia or vascular dementia, compared to people whose risk factors remain stable throughout life. The research is published in the April 20, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Released: 20-Apr-2022 11:00 AM EDT
Einstein Aging Study Receives $32 Million Grant to Study Alzheimer’s Disease
Albert Einstein College of Medicine

To help address the rising tide of Alzheimer’s disease nationwide, researchers at Albert Einstein College of Medicine in collaboration with faculty at Pennsylvania State University and other institutions, have received a five-year, $32 million grant from the National Institutes of Health (NIH) to support the ongoing Einstein Aging Study (EAS), which focuses on both normal aging and the special challenges of Alzheimer’s disease, and other dementias. EAS was established at Einstein in 1980 and has been continuously funded by the NIH.

Released: 20-Apr-2022 2:30 AM EDT
Interferon drives cognitive impairment in Alzheimer’s disease model
Baylor College of Medicine

Alzheimer’s disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities.

Released: 19-Apr-2022 6:05 PM EDT
COVID-19 pneumonia increases dementia risk
University of Missouri, Columbia

Study examined nearly 10,500 patients hospitalized with COVID-19 pneumonia

Released: 19-Apr-2022 4:45 PM EDT
Mayo researchers, collaborators affirm useful blood biomarker for group of brain disorders in new study
Mayo Clinic

A test of protein in the blood gets further support as a biomarker for patients diagnosed with frontotemporal dementia (FTD), a group of brain disorders with few treatment options. These disorders are characterized by changes in behavior, cognition, language or movement.

Released: 11-Apr-2022 12:55 PM EDT
Study Identifies Therapeutic Target for Alzheimer’s Disease, Revealing Strategy for Preventing or Slowing Disease Progression
Case Western Reserve University

A new study from Case Western Reserve University suggests a key protein molecule plays a major role in the accumulation of brain cholesterol, triggering the development of Alzheimer’s and supporting the use of peptide inhibitors as a therapeutic treatment target. The study found that mice, when treated with the peptide inhibitor, demonstrated 50% restored memory function, based on testing such as navigating mazes.

Released: 6-Apr-2022 2:05 PM EDT
Firearm retailers and law enforcement show support for providing safe storage options
University of Colorado Anschutz Medical Campus

A new study discloses that firearm retailers and law enforcement agencies support providing firearm storage to their community.

Released: 5-Apr-2022 3:55 PM EDT
The latest news on clinical trials is here on Newswise
Newswise

Here are some of the latest articles that have been added to the Clinical Trials channel on Newswise.

25-Mar-2022 9:00 AM EDT
Vitamin K Shows Evidence of Brain Benefits in Rats
Federation of American Societies for Experimental Biology (FASEB)

In a new study conducted in rats, scientists report evidence that vitamin K could help protect against aging-related cognitive declines associated with Alzheimer’s disease and other forms of dementia.

Released: 5-Apr-2022 10:20 AM EDT
Late-Onset Alcohol Abuse Can Be a Presenting Symptom of Dementia, Researchers Find
Mount Sinai Health System

Clinical awareness of connection between alcohol and dementia is paramount to providing the best patient care management

Released: 4-Apr-2022 6:05 PM EDT
Funded through an NIH R21 grant, NAU scientists combine PMI and Ecoss expertise to explore the role of gut microbiota in Alzheimer’s disease
Northern Arizona University

Funded through a $418,000 R21 grant from the National Institutes of Health’s National Institute on Aging, assistant professor Emily Cope, associate professor Greg Caporaso and professor Egbert Schwartz recently began working together on “Development of in vivo quantitative stable isotope probing to quantify microbiome dynamics in Alzheimer’s disease.”

Newswise: Hope Builds for New Therapeutics to Reverse or Prevent Alzheimer’s
25-Mar-2022 7:55 AM EDT
Hope Builds for New Therapeutics to Reverse or Prevent Alzheimer’s
American Physiological Society (APS)

A new study from the University of Mississippi Medical Center in Jackson finds that (Aβ) accumulation in AD is associated with reduced blood flow to the brain, known as cerebral hypoperfusion.

Released: 1-Apr-2022 4:25 PM EDT
Combination of biomarkers can identify common cognitive disease
University of Gothenburg

In recent years, subcortical small-vessel disease has become an increasingly common cognitive diagnosis.

Released: 1-Apr-2022 12:05 PM EDT
Half of older adults now die with a dementia diagnosis, up sharply
Michigan Medicine - University of Michigan

Nearly half of all older adults now die with a diagnosis of dementia listed on their medical record, up 36% from two decades ago, a new study shows. But that sharp rise may have more to do with better public awareness, more detailed medical records and Medicare billing practices than an actual rise in the condition, the researchers say.

28-Mar-2022 3:05 PM EDT
Preliminary Study: Drug May Be Safe in Those with Mild Cognitive Impairment, Mild Dementia
American Academy of Neurology (AAN)

A small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Alzheimer’s disease suggests it is safe and may be associated with improvements in executive function, thinking and memory skills. The study is released today, March 31, 2022, and will be presented at the American Academy of Neurology’s 74th Annual Meeting being held in person in Seattle, April 2 to 7, 2022 and virtually, April 24 to 26, 2022. The drug, called SAGE-718, is also in clinical trials for the treatment of cognitive impairment associated with Parkinson’s disease and Huntington’s disease.

Released: 31-Mar-2022 2:35 PM EDT
Researchers Develop Scoring Tool to Measure Severity of Delirium
Beth Israel Deaconess Medical Center

Scientists have developed a novel measure of delirium severity that could help improve patient-centered care for delirium.

Newswise: Cedars-Sinai Neurologists Participate in American Academy of Neurology Conference
Released: 30-Mar-2022 5:05 PM EDT
Cedars-Sinai Neurologists Participate in American Academy of Neurology Conference
Cedars-Sinai

Cedars-Sinai neurology experts are available to discuss the latest advances in research and clinical care for patients with disorders of the nervous system ahead of the 74th annual meeting of the American Academy of Neurology (AAN), happening April 2-7.


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