Feature Channels: Alzheimer's and Dementia

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Newswise: McWilliams School of Biomedical Informatics researchers awarded $6.4M NIH grant to develop deep learning model systems to understand mechanisms of Alzheimer’s disease
Released: 18-Oct-2023 3:05 PM EDT
McWilliams School of Biomedical Informatics researchers awarded $6.4M NIH grant to develop deep learning model systems to understand mechanisms of Alzheimer’s disease
University of Texas Health Science Center at Houston

A five-year, $6.4 million grant to develop an integrated, multiscale artificial intelligence (AI) approach to study genetic factors associated with Alzheimer’s disease has been awarded to UTHealth Houston by the National Institute on Aging, part of the National Institutes of Health.

Newswise:Video Embedded after-50-years-of-pioneering-research-in-rural-louisiana-study-pivots-from-heart-to-brain
VIDEO
Released: 18-Oct-2023 8:00 AM EDT
After 50 years of pioneering research in rural Louisiana, study pivots from heart to brain
Tulane University

A study spent 50 years tracking the health of a rural Louisiana town's children into adulthood and found that heart disease starts in childhood. Now the study hopes decades of heart research can unlock the origins of dementia.

16-Oct-2023 8:00 AM EDT
Adults With ADHD Are at Increased Risk for Developing Dementia
Institute for Health, Health Care Policy and Aging Research at Rutgers University

Michal Schnaider Beeri and team analyzed data from 100,000 people to determine if ADHD in adults leads to higher risk of dementia.

13-Oct-2023 8:05 AM EDT
Dementia’s financial & family impact: New study shows outsize toll
Michigan Medicine - University of Michigan

Most people think of dementia as something that affects a person’s brain. But a new study shows just how much damage it does to a person’s wallet and bank account too – as well as the higher demands it places on their family members -- compared with people of the same age in similar health but without dementia.

9-Oct-2023 11:00 AM EDT
Human Brain Cell Atlas Offers Unprecedented Look at Neuropsychiatric Disorders
University of California San Diego

In a large, multi-institutional effort led by University of California San Diego, researchers have analyzed more than a million human brain cells and revealed links between specific types of cells and various common neuropsychiatric disorders.

Newswise: Insights on disparities in dementia from the UK Biobank study
Released: 11-Oct-2023 5:05 PM EDT
Insights on disparities in dementia from the UK Biobank study
Impact Journals LLC

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 18, entitled, “Pathways explaining racial/ethnic and socio-economic disparities in dementia incidence: the UK Biobank study.”

10-Oct-2023 11:05 AM EDT
New Study Finds Link Between Subjective and Objective Memory Decline
American Academy of Neurology (AAN)

Among people who report memory and thinking problems, some show no signs of a problem on standard tests, while others have subtle declines on their tests. A new study shows that people who have subtle problems with these tests may have an increased risk of developing mild cognitive impairment, which can be a precursor to dementia. The study is published in the October 11, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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This news release is embargoed until 9-Oct-2023 5:00 PM EDT Released to reporters: 3-Oct-2023 2:00 PM EDT

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Newswise: Michal Schnaider Beeri Appointed Jacqueline Krieger Klein Endowed Director’s Chair
In Neurodegeneration Research
Released: 6-Oct-2023 10:05 AM EDT
Michal Schnaider Beeri Appointed Jacqueline Krieger Klein Endowed Director’s Chair In Neurodegeneration Research
Rutgers University-New Brunswick

The Board of Governors named Michal Schnaider Beeri, a global leader in Alzheimer’s disease clinical research and director of the Herbert and Jacqueline Krieger Klein Alzheimer’s and Dementia Clinical Research and Treatment Center, as its Endowed Chair in Neurodegenerative Research.

Newswise: Corewell Health neuroscientist leads research to tackle disparate growth of Alzheimer’s among Black Americans
Released: 5-Oct-2023 8:05 PM EDT
Corewell Health neuroscientist leads research to tackle disparate growth of Alzheimer’s among Black Americans
Corewell Health

To address the growing disparity and identify multi-level risk factors impacting the higher prevalence of Alzheimer’s disease among middle-aged and older Black adults, Corewell Health neuroscientist Stewart Graham, Ph.D., in collaboration with researchers from Hampton University, Johns Hopkins and Clemson are spearheading a first-of-its-kind, five-year, $4.8 million research project.

Newswise: Study Maps Brain Wave Disruptions Affecting Memory Recall
Released: 5-Oct-2023 2:50 PM EDT
Study Maps Brain Wave Disruptions Affecting Memory Recall
UT Southwestern Medical Center

The brain circuitry that is disrupted in Alzheimer’s disease appears to influence memory through a type of brain wave known as theta oscillation, a team led by UT Southwestern Medical Center researchers report. The findings, published in Nature Communications, could help researchers design and evaluate new treatments for Alzheimer’s, a condition that affects millions of people around the globe and has no cure.

Newswise: Cerebral amyloid angiopathy, seizures, and epilepsy: Dr. Brin Freund
Released: 4-Oct-2023 2:05 PM EDT
Cerebral amyloid angiopathy, seizures, and epilepsy: Dr. Brin Freund
International League Against Epilepsy

Sixty percent of patients with dementia on autopsy studies have cerebral amyloid angiopathy (CAA) pathology. This episode discusses the relationship between CAA and epilepsy through the lens of a recent publication. Dr. Alina Ivaniuk talks with Dr. Brin Freund.

Released: 3-Oct-2023 6:05 AM EDT
Researchers find a cause of Parkinson’s disease
University of Copenhagen, Faculty of Health and Medical Sciences

Until recently, our understanding of Parkinson's disease has been quite limited, which has been apparent in the limited treatment options and management of this debilitating condition.

Released: 3-Oct-2023 6:05 AM EDT
Study indicates possible link between chronic stress and Alzheimer’s disease
Karolinska Institute

Researchers from Karolinska Institutet have published a study in Alzheimer's Research & Therapy that addresses possible associations between chronic stress, mild cognitive impairment and Alzheimer’s disease.

Released: 3-Oct-2023 6:05 AM EDT
New $81M NIH grant will help U.S. answer urgent need for better dementia care
Michigan Medicine - University of Michigan

Fueled by new five-year funding expected to total $81 million from the NIH’s National Institute on Aging, a multi-institution team will work to improve understanding of the health care workforce that cares for people with dementia, through surveys and other methods that will produce data for clinicians, researchers, policymakers and others to use.

Released: 2-Oct-2023 12:00 PM EDT
Rutgers Receives $4.2 Million to Develop Center for Alzheimer’s and Dementia Research in Asian and Pacific Americans
Institute for Health, Health Care Policy and Aging Research at Rutgers University

The Resource Center for Alzheimer’s and Dementia Research in Asian and Pacific Americans will work to advance behavioral, social and economic research related to Alzheimer’s disease and other dementias especially in older Asian and Pacific Americans.

Newswise: Study Links Sleep Duration with Brain Volume in Older Hispanic Adults
Released: 29-Sep-2023 12:05 PM EDT
Study Links Sleep Duration with Brain Volume in Older Hispanic Adults
University of Miami Health System, Miller School of Medicine

The work of principal investigator Alberto Ramos, M.D., M.S., underscores the importance of sleep studies for a group that has an elevated risk for Alzheimer’s disease.

Released: 27-Sep-2023 12:50 PM EDT
Stay informed on women's health issues in the Women's Health channel
Newswise

Below are some of the latest headlines in the Women's Health channel on Newswise.

Newswise: Do cyanobacteria make the neurotoxin β-N-methylamino-L-alanine (BMAA)?
Released: 23-Sep-2023 10:30 AM EDT
Do cyanobacteria make the neurotoxin β-N-methylamino-L-alanine (BMAA)?
Chinese Academy of Sciences

The cyanobacterial origin of β-N-methylamino-L-alanine (BMAA), an environmental neurotoxin, remains controversial. With a carefully designed genetic system as a control, we found no evidence for the production of BMAA by cyanobacteria from lab cultures or bloom samples.

Newswise: Phototherapy of Alzheimer’s disease during sleep
Released: 22-Sep-2023 3:25 PM EDT
Phototherapy of Alzheimer’s disease during sleep
Higher Education Press

It is well known that sleep is the best medication. However, it is still unknown why the brain recovers better in sleep and whether these processes can be controlled.

Newswise: Researchers Connect Alzheimer’s-Associated Genetic Variants with Brain Cell Function
Released: 22-Sep-2023 8:05 AM EDT
Researchers Connect Alzheimer’s-Associated Genetic Variants with Brain Cell Function
University of North Carolina School of Medicine

Led by scientists at UNC-Chapel Hill and UC-San Francisco, research reveals new non-coding genetic variants associated with Alzheimer’s disease functioning in microglia – brain cells already implicated in the progression of this often-fatal neurodegenerative condition.

Newswise: How do toxic proteins accumulate in Alzheimer’s and other diseases?
Released: 21-Sep-2023 12:05 PM EDT
How do toxic proteins accumulate in Alzheimer’s and other diseases?
Washington University in St. Louis

The normal brain protein tau sometimes gets knotted up into tangles and turns toxic, injuring brain tissue and causing tauopathies, a group of brain diseases characterized by problems with learning, memory and movement.

Released: 21-Sep-2023 9:30 AM EDT
World Alzheimer’s Month 2023: Shining a Light on Alzheimer's – Domenico Praticò
Alzheimer's Center at Temple University Lewis Katz School of Medicine

Since 2012, September has been celebrated as World Alzheimer’s Month. Back then, and only eleven years ago, an average of 2 out of 3 people had little understanding of Alzheimer's disease and associated dementias.

Released: 21-Sep-2023 8:05 AM EDT
UCLA Health Tip Sheet September 2023
University of California, Los Angeles (UCLA), Health Sciences

Below is a brief roundup of news and story ideas from the experts at UCLA Health. For more information on these stories or for help on other stories, please contact us at [email protected].

Newswise: FAU Receives $1.3 Million Grant for Alzheimer’s Outreach in Broward County
Released: 20-Sep-2023 8:30 AM EDT
FAU Receives $1.3 Million Grant for Alzheimer’s Outreach in Broward County
Florida Atlantic University

The three-year, $1.3 million grant from the Administration for Community Living’s Alzheimer’s Disease Program Initiative will support a groundbreaking project designed to advance health equity and improve quality of life for individuals living with or at high risk for Alzheimer’s disease and related dementias and their family caregivers.

Released: 19-Sep-2023 8:05 AM EDT
Cholesterol and Inflammation Demonstrate Alzheimer’s Link
Alzheimer's Center at Temple University Lewis Katz School of Medicine

A recent study shows that a protein called ABCA7 plays a functional role as a potential biological link between cholesterol and inflammation in Alzheimer’s disease. The new work was published online August 25 in the journal Cells.

Newswise: UTSW study challenges classic tenet of memory research
Released: 18-Sep-2023 11:05 AM EDT
UTSW study challenges classic tenet of memory research
UT Southwestern Medical Center

Connections among one set of activated neurons in rat brains grew stronger while memories were being formed, but those in another weakened, UT Southwestern Medical Center researchers discovered.

Newswise: FAU Receives $750,000 Philanthropic Grant for Alzheimer’s Disease
Released: 18-Sep-2023 8:30 AM EDT
FAU Receives $750,000 Philanthropic Grant for Alzheimer’s Disease
Florida Atlantic University

A $750,000 philanthropic grant from the Carl Angus DeSantis Foundation will help FAU develop partnerships and programs that will establish best practice for coordinated care and research for Alzheimer’s disease and related dementias.

Released: 18-Sep-2023 4:00 AM EDT
Alerta para los expertos: avances en el tratamiento para el alzhéimer mediante un enfoque integral
Mayo Clinic

El lecanemab ha llamado la atención en todo el mundo por ser el medicamento aprobado recientemente para la enfermedad de Alzheimer y el primer tratamiento aprobado por la FDA para el alzhéimer en más de 20 años.

Released: 18-Sep-2023 4:00 AM EDT
Alerta do especialista: o avanço no tratamento do Alzheimer por meio de uma abordagem abrangente
Mayo Clinic

O lecanemabe recebeu atenção mundial depois de ter sido o medicamento mais recente aprovado para a doença de Alzheimer e o primeiro tratamento aprovado para Alzheimer pela Administração de Alimentos e Medicamentos (Food and Drug Administration, FDA) dos EUA em mais de 20 anos.

Released: 18-Sep-2023 4:00 AM EDT
تنبيه من خبير: تطوير خيار علاجي للتعامل مع مرض الزهايمر من خلال نهج شامل
Mayo Clinic

مدينة روتشستر، ولاية مينيسوتا — حظى دواء ليكانيماب باهتمام عالمي كأحدث خيار علاجي معتمد للتعامل مع داء الزهايمر وأول دواء معتمد من إدارة الغذاء والدواء الأمريكية منذ أكثر من 20 عامًا. دونانيماب، هو دواء آخر من نفس الفئة في طور المراجعة للحصول على الاعتماد نفسه. ويتوقع أن يُعتمد خلال هذا العام. يقول فيجاي رامانان، دكتور في الطب، حاصل على دكتوراه اختصاصي الأعصاب السلوكي في مايو كلينك في مدينة روتشستر، بولاية مينيسوتا أنه من المهم النظر إلى هذه الخيارات الجديدة كجزء محتمل من خطة علاجية شاملة.

Newswise: Optogenetic stimulation of astrocytes against Alzheimer's disease
Released: 18-Sep-2023 3:05 AM EDT
Optogenetic stimulation of astrocytes against Alzheimer's disease
Scientific Project Lomonosov

Scientists at Peter the Great St. Petersburg Polytechnic University demonstrated that optogenetic stimulation of hippocampal astrocytes can have a positive effect on the course of the Alzheimer's disease. At the very least, it worked in a mouse model of the disease.

Newswise: Devastating causes of childhood dementia revealed
Released: 18-Sep-2023 12:05 AM EDT
Devastating causes of childhood dementia revealed
University of Adelaide

It is a heartbreaking condition that robs children of their ability to walk, talk and recognise their loved ones and now the latest research has revealed the true impact of childhood dementia globally.

Newswise: Emily Rogalski joins UChicago to lead new center for healthy brain aging, Alzheimer's and related diseases
Released: 13-Sep-2023 8:05 AM EDT
Emily Rogalski joins UChicago to lead new center for healthy brain aging, Alzheimer's and related diseases
University of Chicago Medical Center

The new University of Chicago Healthy Aging & Alzheimer's Research Care (HAARC) Center will focus on building deep multidisciplinary expertise and bridging the gap between scientific disciplines to accelerate breakthroughs in cognitive resilience.

Newswise: Using Focused Ultrasound to Treat Alzheimer’s and Parkinson’s
Released: 12-Sep-2023 1:05 PM EDT
Using Focused Ultrasound to Treat Alzheimer’s and Parkinson’s
Columbia University School of Engineering and Applied Science

Using gene therapy to treat many neurologic diseases, such as Alzheimer’s and Parkinson’s, has long been a long-sought goal of researchers, but the blood-brain barrier has proven very difficult to cross.

   
Newswise: Researchers Create a New Window on Leading Genetic Cause of Alzheimer’s
Released: 12-Sep-2023 10:00 AM EDT
Researchers Create a New Window on Leading Genetic Cause of Alzheimer’s
Pacific Northwest National Laboratory

Scientists have opened a new view into the workings of the brain and central nervous system, detecting a diverse set of important molecules known as lipoproteins. The most common protein on the particles is apolipoprotein E; one form of APOE puts people at higher risk of Alzheimer’s disease.

Released: 12-Sep-2023 8:45 AM EDT
New Anti-amyloid Drugs are Providing Hope for People with Alzheimer’s Disease – Now What?
American Neurological Association (ANA)

Newly approved anti-amyloid therapies that slow Alzheimer’s disease progression offer new hope for people with the disorder.

Newswise: $50 million gift to expand health sciences research at Virginia Tech
Released: 12-Sep-2023 7:05 AM EDT
$50 million gift to expand health sciences research at Virginia Tech
Virginia Tech

The Richmond, Virginia-based Red Gates Foundation recently committed $50 million to the Fralin Biomedical Research Institute at VTC to accelerate health sciences research at Virginia Tech. The gift is among the largest ever made to the university.

Newswise: McWilliams School of Biomedical Informatics researchers awarded $3.4M NIH grant to understand link between chronic health conditions and Alzheimer's disease
Released: 8-Sep-2023 12:00 PM EDT
McWilliams School of Biomedical Informatics researchers awarded $3.4M NIH grant to understand link between chronic health conditions and Alzheimer's disease
University of Texas Health Science Center at Houston

A three-year, $3.4 million grant to investigate how Alzheimer’s disease is connected to multiple chronic diseases has been awarded to UTHealth Houston researchers by the National Institute on Aging, part of the National Institutes of Health.

Newswise: Specialized T cells in the brain slow progression of Alzheimer’s disease
Released: 7-Sep-2023 12:05 PM EDT
Specialized T cells in the brain slow progression of Alzheimer’s disease
St. Jude Children's Research Hospital

Scientists at St. Jude Children’s Research Hospital found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer’s disease.

Released: 7-Sep-2023 11:05 AM EDT
Are antipsychotic drugs being appropriately prescribed to homebound patients with dementia?
Wiley

New research published in the Journal of the American Geriatrics Society indicates that antipsychotics are likely overprescribed and used inappropriately among patients with Alzheimer’s disease and related dementias (ADRD) receiving home health care, and such use is linked to worse patient outcomes.

Newswise: SMU professor wins $1.8M NIH award to study how our bodies may work to repair damaged components in cells
Released: 7-Sep-2023 9:55 AM EDT
SMU professor wins $1.8M NIH award to study how our bodies may work to repair damaged components in cells
Southern Methodist University

SMU biology professor Zhihao Wu has received a $1.8 million, 5-year Maximizing Investigators' Research Award (MIRA) from the National Institutes of Health to determine if different quality control pathways in our bodies might be working together to repair damaged components in cells.

Newswise: Gene Discovery Nets FAU Researchers U.S. Patent for Molecular Approach to Treat Addiction
Released: 7-Sep-2023 8:30 AM EDT
Gene Discovery Nets FAU Researchers U.S. Patent for Molecular Approach to Treat Addiction
Florida Atlantic University

Researchers have received a U.S. patent for a novel method to identify therapeutic agents to treat addiction. The invention, related to the fields of pharmacology, medicine, neurology and psychiatry, targets the protein MBLAC1, which the Blakely lab identified as the mammalian form of a gene the group first identified in worms as a modifier of signaling by the neurotransmitter dopamine.

Newswise: IU researchers identify new gene mutation that alters Alzheimer’s disease risk
Released: 6-Sep-2023 11:05 AM EDT
IU researchers identify new gene mutation that alters Alzheimer’s disease risk
Indiana University

A groundbreaking study led by experts from Indiana University School of Medicine has shed new light on the genetic underpinnings of Alzheimer's disease.

Released: 6-Sep-2023 11:05 AM EDT
New Columbia Nursing study on AI tool for detecting Alzheimer’s and related dementias shows promising results
Columbia University School of Nursing

A new Columbia Nursing study analyzes the performance of ADscreen, a computerized speech processing algorithm that is being developed to support clinicians in detecting and monitoring the progression of Alzheimer's disease and related dementias early.

Newswise: Timothy Huang awarded $2.6M to solve Alzheimer’s disease puzzle
Released: 6-Sep-2023 5:00 AM EDT
Timothy Huang awarded $2.6M to solve Alzheimer’s disease puzzle
Sanford Burnham Prebys

With the help of a new grant from the National Institutes of Health for more than $2.6 million, Assistant Professor Timothy Huang, Ph.D., will continue his research on the role of the brain’s immune cells on the risk of developing Alzheimer’s disease.

Newswise: Phase I Clinical Trial Shows Treatment Designed to Clear Senescent Cells in Alzheimer’s Disease Is Safe
Released: 5-Sep-2023 3:00 PM EDT
Phase I Clinical Trial Shows Treatment Designed to Clear Senescent Cells in Alzheimer’s Disease Is Safe
Wake Forest University School of Medicine

Scientists at Wake Forest University School of Medicine are reporting results from a Phase I trial in an area of promising research for Alzheimer's disease—cellular senescence.

Released: 1-Sep-2023 8:00 AM EDT
Blood biomarker shows “great promise” predicting progression to Alzheimer’s disease in at-risk population
Wayne State University Division of Research

Neuroscience researchers at Wayne State University published a review article that confirms the usefulness of neurofilament light (NfL) blood levels to predict the likelihood and rate of progression of neurodegeneration in Alzheimer’s disease.

Newswise: Statewide project to provide care and support to people living with dementia and their care partners
Released: 30-Aug-2023 7:30 AM EDT
Statewide project to provide care and support to people living with dementia and their care partners
Indiana University

An Indiana University School of Medicine statewide project in collaboration with Indiana University Health was recently funded to support people living with dementia as well as their family care partners find more support and resources, thanks to a new $686,000 grant from the National Institute on Aging IMPACT Collaboratory.



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