Among Indigenous, rural non-industrial populations inhabiting the tropical forests of lowland Bolivia, researchers report, there appears to be an optimal balance between levels of food consumption and exercise that maximizes healthy brain aging and reduces the risk of disease.
Global pharmaceutical company Takeda has agreed to exclusively license a group of small molecules that target tau – a protein in which misfolding and aggregation are believed to be a cause of Alzheimer’s disease.
UNC School of Medicine scientists demonstrated that stimulating a brain region called Supramammilary nucleus (SuM) located in the hypothalamus effectively enhanced adult-born neurons in the otherwise impaired Alzheimer’s brains of mice.
New research from the UC Davis School of Medicine shows high blood pressure in early adulthood is associated with worse brain health in late life — especially for men. The results suggest that treating hypertension in young and middle-aged adults may help prevent dementia and Alzheimer’s disease.
People with Alzheimer’s disease develop defects in cognitive functions like memory as well as problems with noncognitive functions that can lead to anxiety and depression.
In an analysis of published clinical trials, investigators found that phototherapy—or exposure to sessions of bright light—may be a promising non-pharmacological intervention for lessening symptoms of dementia.
A 5-year, $41 million study will help researchers better understand the biological pathways underlying Alzheimer’s disease and ultimately create more personalized patient care through the development of a blood test for multiple pathways implicated in the disease – enabling earlier and less-invasive diagnosis.
Following a Mediterranean-based ketogenic diet may decrease the risk of Alzheimer’s disease, according to a new study from scientists at Wake Forest University School of Medicine.
Getting sick often may impact how quickly the brain ages and increase the risk of dementia or other forms of cognitive decline.
Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging.
New research at the University of Massachusetts Amherst zeroes in on the root cause of adverse health effects from disruption of the body’s circadian rhythms, which typically occurs from jet lag and rotating work shifts.
Harrington Discovery Institute Center for Brain Health Medicines at University Hospitals and the Alzheimer's Drug Discovery Foundation (ADDF) announce a joint request for proposal for the 2023 ADDF-Harrington Scholar Award. The ADDF-Harrington Scholar Award is designed to accelerate the translation of innovative research that could treat, prevent, slow, or reverse Alzheimer's disease or related dementias.
A roundup of the latest medical discoveries and faculty news happening at Cedars-Sinai in March 2023.
Researchers at Boston University, USA report that the flow of cerebrospinal fluid in the brain is linked to waking brain activity.
Once adults reach age 65, the threshold age for the onset of Alzheimer’s disease, the extent of their genetic risk may outweigh age as a predictor of whether they will develop the fatal brain disorder, a new study suggests.
A study from the UC Davis School of Medicine has identified a gene-enzyme interaction that appears to play a key role in how the brain forms memories. The findings provide insights into how PDE inhibitor medications may help diseases like Alzheimer’s. The research was published in Science Signaling.
From septic shock to sticker shock. Keep up with this ever-growing, changing sector. Below are some of the latest stories on healthcare on Newswise.
Alzheimer's disease affects people of all ethnic groups. Armed with $41 million in new federal funding, Mayo Clinic researchers and colleagues from 13 other institutions around the country are pursuing three multiethnic projects to identify targets for treatment.
For the first time, researchers have developed a form of the omega-3 fatty acid docosahexaenoic acid (DHA) that is capable of crossing into the eye’s retina to ward off visual declines related to Alzheimer’s disease, diabetes and other disorders.
A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases. The study, published in Nature Communications, offers key insights that could help identify new treatments for patients.
People who have low bone density may have an increased risk of developing dementia compared to people who have higher bone density, according to a study published in the March 22, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that low bone density causes dementia. It only shows an association.
Depression in Alzheimer's has different risk factors than depression in older adults without the disease, finds a major new study in the Journal of Alzheimer’s Disease. The University of Bristol-led research looked at over 2,000 people with the disease to explain why current anti-depressants are ineffective for people living with depression in Alzheimer’s.
Researchers from the Uniformed Services University (USU) have shed light on a fatal neurodegenerative disease that has long afflicted the native Chamorro people living on Guam – a unique and mystifying disorder that has baffled scientists for decades.
University of Delaware associate professor Matthew Cohen offers 11 signs and symptoms that might suggest a health condition, such as dementia, that affects thinking. Cohen is associate director of the Delaware Center for Cognitive Aging Research.
Walking is a complex task that is most commonly performed while completing other tasks like talking, reading signs, or making decisions.
UC San Diego researchers use a DNA designer drug to restore key protein levels in motor neurons, delaying paralysis in a mouse model of ALS.
It started with a hunt for lab space and ended with a collaboration born out of what the researchers call a “cosmic coincidence.”
Eating a traditional Mediterranean-type diet – rich in foods such as seafood, fruit, and nuts – may help reduce the risk of dementia by almost a quarter, a new study has revealed.
The risk of death rises among older adults with Alzheimer's or other dementias in the months following exposure to a hurricane, a new University of Michigan study shows.
Keck Medicine of USC has launched a clinical trial to study the effect of a novel hormone replacement therapy on postmenopausal cardiovascular disease and cognitive decline.
Scientists from the Trinity Biomedical Sciences Institute (TBSI) have shed new light on ageing processes in the brain. By linking the increased presence of specialised immune cells to conditions such as Alzheimer’s disease and traumatic brain injury for the first time, they have unearthed a possible new target for therapies aimed at treating age-related neurological diseases.
People who eat diets rich in green leafy vegetables as well as other vegetables, fruits, whole grains, olive oil, beans, nuts and fish may have fewer amyloid plaques and tau tangles in their brain—signs of Alzheimer’s disease—than people who do not consume such diets, according to a study published in the March 8, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
In 2020, the first year of the COVID-19 pandemic, dementia was the dominant risk factor for the disease among residents of Swedish nursing homes.
In a large study of diverse adults in California, individuals with newly diagnosed atrial fibrillation, or an irregular heart rhythm, had a modestly elevated risk of developing dementia.
Dementia in India may be higher than previous estimates have suggested and could be more in line with prevalence rates for countries such as the United States and the United Kingdom, according to a new collaborative study by researchers from the University of Surrey, University of Southern California, University of Michigan, and All India Institute of Medical Sciences.
Scientific evidence shows how the cognitive decline in Alzheimer’s disease (AD) is caused by the buildup of amyloid beta proteins, which promote synaptic malfunction.
In Alzheimer’s and related neurodegenerative diseases, the brain protein tau is closely linked to brain damage and cognitive decline. A new study from researchers at Washington University School of Medicine in St. Louis indicates that T cells play a key role in tau-related neurodegeneration, a finding that suggests new treatment strategies for Alzheimer’s and related diseases.
Adding to the growing body of evidence on sleep disturbances and cognitive impairment, new research finds significant links between three measures of sleep disturbance and the risk for developing dementia over a 10-year period.
Reducing the methylation of a key messenger RNA can promote migration of macrophages into the brain and ameliorate symptoms of Alzheimer’s disease in a mouse model, according to a new study publishing March 7th in the open access journal PLOS Biology by Rui Zhang of Air Force Medical University in Xian, Shaanxi, China. The results illuminate one pathway for entrance of peripheral immune cells into the brain, and may provide a new target for treatment of Alzheimer’s disease.
Cedars-Sinai investigators have produced the most extensive analysis to date of changes in the retina—a layer of tissue at the back of the eye where visual information originates—and how those retinal changes correspond to brain and cognitive changes in Alzheimer’s disease patients.
Researchers at Chalmers University of Technology in Sweden have developed a method for predicting fall accidents and cognitive illnesses such as Alzheimer’s disease by reading a person’s walking pattern with the aid of a radar sensor.
Three faculty from the Perelman School of Medicine at the University of Pennsylvania have been named 2023 Hastings Center Fellows. Emily Largent, PhD, RN, Peter Reese, MD, PhD, and Dominic Sisti, PhD, are among 12 new Fellows joining an elected group of over 200.
Researchers at the University of Calgary’s Hotchkiss Brain Institute in Canada and the University of Exeter in the UK explored the relationship between vitamin D supplementation and dementia in more than 12,388 participants of the US National Alzheimer's Coordinating Center, who had a mean age of 71 and were dementia-free when they signed up.
Cleveland: A self-administered screening tool, developed by Cleveland Clinic researchers, can effectively and efficiently assess cognition issues in older adults.
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A new technique that targets and breaks apart certain proteins — rather than just interfering with them — may offer a pathway toward treatment of Alzheimer's disease. Researchers reporting in ACS Central Science have designed a compound that breaks down a protein closely associated with the disease.
According to new research from Wake Forest University School of Medicine, people who experience discrimination during their lifetimes have an increased risk of dementia. The study appears in the February issue of Alzheimer’s & Dementia, the journal of the Alzheimer’s Association.
New research that followed female participants for two decades has found that seven healthy habits and lifestyle factors may play a role in lowering the risk of dementia. The preliminary study released today, February 27, 2023, will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023.
Black people are receiving medications for dementia less often than white people, according to a preliminary study released today, February 26, 2023, that will be presented at the American Academy of Neurology’s 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023.
Northwestern Medicine scientists have discovered two ways to preserve diseased upper motor neurons that would normally be destroyed in ALS, based on a study in mice. Upper motor neurons initiate movement, and they degenerate in ALS.
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